IL72642A - Circular dna plasmid for use as transformation vector - Google Patents

Circular dna plasmid for use as transformation vector

Info

Publication number
IL72642A
IL72642A IL72642A IL7264284A IL72642A IL 72642 A IL72642 A IL 72642A IL 72642 A IL72642 A IL 72642A IL 7264284 A IL7264284 A IL 7264284A IL 72642 A IL72642 A IL 72642A
Authority
IL
Israel
Prior art keywords
circular dna
transformation vector
dna plasmid
plasmid
transformation
Prior art date
Application number
IL72642A
Other languages
English (en)
Other versions
IL72642A0 (en
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL72642A0 publication Critical patent/IL72642A0/xx
Priority to IL99611A priority Critical patent/IL99611A0/xx
Publication of IL72642A publication Critical patent/IL72642A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL72642A 1983-08-10 1984-08-10 Circular dna plasmid for use as transformation vector IL72642A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL99611A IL99611A0 (en) 1983-08-10 1991-09-29 Dna plasmids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52196483A 1983-08-10 1983-08-10
US06/636,727 US4710473A (en) 1983-08-10 1984-08-06 DNA plasmids

Publications (2)

Publication Number Publication Date
IL72642A0 IL72642A0 (en) 1984-11-30
IL72642A true IL72642A (en) 1993-04-04

Family

ID=27060650

Family Applications (2)

Application Number Title Priority Date Filing Date
IL9961184A IL99611A (en) 1983-08-10 1984-08-10 Small stabilized ILOC .E plasmids
IL72642A IL72642A (en) 1983-08-10 1984-08-10 Circular dna plasmid for use as transformation vector

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL9961184A IL99611A (en) 1983-08-10 1984-08-10 Small stabilized ILOC .E plasmids

Country Status (7)

Country Link
US (2) US4710473A (de)
EP (1) EP0136490B1 (de)
JP (1) JPH0797991B2 (de)
CA (1) CA1312026C (de)
DE (1) DE3481716D1 (de)
IL (2) IL99611A (de)
WO (1) WO1985000829A1 (de)

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KR850004274A (ko) * 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
US5126252A (en) * 1984-08-27 1992-06-30 Bio-Technology General Corp. Expressions vectors containing Lambda PL promoter and T1 T2 RNA termination sequence, plasmids containing the vectors, hosts containing the plasmids and relatedmethods
US5081020A (en) * 1984-08-27 1992-01-14 Bio-Technology General Corp. Expression vectors containing λPL promoter, T1 T2 rRNA termination sequence and origin of replication derived from a constitutive high copy number plasmid hosts and related methods
US5759816A (en) * 1984-08-27 1998-06-02 Bio-Technology General Corp. Expression vectors containing λPL promoter and T1 T2 rRNA termination sequence plasmids containing the vectors hosts containing the plasmids and related methods
JP2594535B2 (ja) * 1984-11-30 1997-03-26 サントリー株式会社 高発現ベクターおよびその利用
US4810643A (en) * 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
JPS63500636A (ja) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 多分化能性顆粒球コロニー刺激因子をコードするｄｎａ
US6004548A (en) 1985-08-23 1999-12-21 Amgen, Inc. Analogs of pluripotent granulocyte colony-stimulating factor
US5110731A (en) * 1985-08-26 1992-05-05 Amgen, Inc. System for biotin synthesis
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
US5240837A (en) * 1987-02-19 1993-08-31 The Upjohn Company CDNAS encoding somatotropin, expression vectors and hosts
JP2580303B2 (ja) * 1987-02-19 1997-02-12 ジ・アップジョン・カンパニー 異種蛋白をコ−ド付けするｃＤＮＡ類、発現ベクタ−類および宿主類
US5366081A (en) 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5472702A (en) * 1987-08-26 1995-12-05 United States Surgical Corporation Sterilization of growth factors
US5222978A (en) 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US4885252A (en) * 1987-09-08 1989-12-05 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans
US5599690A (en) * 1988-02-01 1997-02-04 Amgen Inc. Control of norleucine incorporation into recombinant proteins
US5714465A (en) * 1989-05-19 1998-02-03 Amgen Inc. Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor
AU648505B2 (en) 1989-05-19 1994-04-28 Amgen, Inc. Metalloproteinase inhibitor
US5359831A (en) 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
US5434135A (en) * 1990-08-02 1995-07-18 Indu Parikh Growth factor compositions, preparation and use
IL99100A0 (en) * 1990-08-13 1992-07-15 Lilly Co Eli Improved bacteriophage lambda pl promoters
AU8728691A (en) * 1990-09-28 1992-04-28 Amgen, Inc. Cloning cartridges and expression vectors in gram-negative bacteria
CA2057715A1 (en) * 1990-12-19 1992-06-20 Charles L. Hershberger Method for enhancing the structural stability of recombinant dna expression vectors
CA2059245C (en) * 1991-02-08 2004-07-06 Michael P. Chesterfield Method and apparatus for calendering and coating/filling sutures
US5395761A (en) * 1991-11-27 1995-03-07 Eli Lilly And Company Plasmid pHKY334, an expression vector for EK-BGH and host cells transformed therewith
IL107642A0 (en) * 1992-11-20 1994-02-27 Amgen Inc Progenitor b cell stimulating factor
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US6562596B1 (en) * 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor
US5574008A (en) 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
IL117175A (en) * 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US5904716A (en) * 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
US6369027B1 (en) 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin
US20030207827A1 (en) * 1995-12-22 2003-11-06 William J. Boyle Osteoprotegerin
US7632922B1 (en) * 1995-12-22 2009-12-15 Amgen, Inc. Osteoprotegerin
US20050147611A1 (en) * 1995-12-22 2005-07-07 Amgen Inc. Combination therapy for conditions leading to bone loss
HUP0001650A3 (en) * 1996-11-08 2001-09-28 Neose Technologies Inc Horsham Improved expression vectors
NZ335207A (en) 1996-11-15 2000-09-29 Genentech Inc Process to isolate recombinant human neurotrophin using hydrophobic chromatography resin
AU713473B2 (en) 1996-12-23 1999-12-02 Immunex Corporation Receptor activator of NF-kappa B, receptor is member of TNF receptor superfamily
KR100496063B1 (ko) * 1997-04-15 2005-06-21 산쿄 가부시키가이샤 신규단백질 및 그 제조방법
RO128635A2 (ro) 1997-04-16 2013-07-30 Amgen Inc. Anticorp sau fragment al acestuia care se leagă la opgbp şi utilizarea acestuia, utilizarea unei forme solubile de odar, şi metodă de identificare a unui compus care descreşte activitatea opgbp
US6316408B1 (en) * 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
US6265542B1 (en) 1997-10-24 2001-07-24 Genentech, Inc. Purification of molecules
ATE362374T1 (de) * 1999-09-03 2007-06-15 Amgen Inc Verfahren und zusammensetzungen zur prevention oder behandlung von krebs und von krebs assoziertem knochenverlust
US7223559B2 (en) * 2000-04-06 2007-05-29 Kyowa Hakko Kogyo Co., Ltd. Plasmids for chromosomal recombination of Escherichia coli
US6780405B1 (en) * 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
EP1315513B1 (de) * 2000-09-08 2011-03-09 Amylin Pharmaceuticals, Inc. "pseudo"-native chemische ligation
AU3944002A (en) 2000-11-03 2002-05-27 Genentech Inc Metabolic rate shifts in fermentations expressing recombinant proteins
EP1921088B1 (de) 2001-05-11 2014-10-08 Amgen Inc. Peptide und damit zusammenhängende an Tall-1 bindende Moleküle
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
EP1494714A4 (de) 2002-04-05 2008-03-05 Amgen Inc Humane anti-opgl-neutralisierende antikörper als selektive opgl-pfad-hemmer
US6919426B2 (en) 2002-09-19 2005-07-19 Amgen Inc. Peptides and related molecules that modulate nerve growth factor activity
CA2543484C (en) 2003-10-27 2014-02-04 Amgen Inc. Modulation of immune response to an immunogen with ctla-4 and tnfbp
ME00226B (me) 2004-07-15 2011-02-10 Medarex Llc Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
EP1960363B1 (de) * 2005-12-09 2014-01-22 Amgen, Inc. Verbindungen auf chinolonbasis mit prolylhydroxylasehemmender wirkung sowie zusammensetzungen und anwendungen davon
DE602007012412D1 (de) 2005-12-22 2011-03-24 Genentech Inc Rekombinante produktion heparinbindender proteine
WO2008008975A2 (en) 2006-07-14 2008-01-17 Genentech, Inc. Refolding of recombinant proteins
EP2097416B1 (de) * 2006-12-18 2012-09-12 Amgen, Inc Verbindungen auf azachinolonbasis mit prolyl-hydroxylase-hemmerwirkung, zusammensetzungen und ihre verwendung
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ES2442847T3 (es) * 2007-04-18 2014-02-13 Amgen, Inc Quinolonas y azaquinolonas que inhiben la prolil hidroxilasa
EP2155680B1 (de) * 2007-04-18 2013-12-04 Amgen, Inc Prolylhydroxylase hemmende indanonderivate
WO2008137084A2 (en) * 2007-05-04 2008-11-13 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
ES2389063T3 (es) * 2007-05-04 2012-10-22 Amgen, Inc Derivados de tienopiridina y tiazolopiridina que inhiben la actividad prolil hidroxilasa
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DE2759053A1 (de) * 1977-12-30 1979-07-12 Uhlin Verfahren zum herstellen von genprodukten von plasmid-dns
FI793884A (fi) * 1978-12-26 1980-06-27 Cetus Corp Stabila plasmider med stort kopieantal
US4374927A (en) * 1981-02-24 1983-02-22 The Board Of Trustees Of The Leland Stanford Jr. University Extrachromosomal regulation of expression
CA1198067A (en) * 1981-02-27 1985-12-17 David H. Gelfand Stable high copy number plasmids
EP0108132A1 (de) * 1982-05-06 1984-05-16 Applied Molecular Genetics Inc. Herstellung und expression von genen für urogastron und dessen polypeptidanalogen
CA1209501A (en) * 1982-09-16 1986-08-12 Nikos Panayotatos Expression vector
WO1984001150A1 (en) * 1982-09-16 1984-03-29 Amgen Avian growth hormones
DK410783D0 (da) * 1982-09-16 1983-09-09 Benzon A Salfred Fremgangsmade til stabilisering af plasmider
JPH0753111B2 (ja) * 1982-09-16 1995-06-07 ベンツォン ファーマ エイ／エス 条件非制御の複製挙動を持つプラスミド
NL8203716A (nl) * 1982-09-24 1984-04-16 Tno Dna en plasmiden.
GB8308236D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Dna vectors

Also Published As

Publication number Publication date
CA1312026C (en) 1992-12-29
US5674746A (en) 1997-10-07
IL99611A (en) 1994-01-25
EP0136490A2 (de) 1985-04-10
EP0136490A3 (en) 1985-10-09
JPH0797991B2 (ja) 1995-10-25
EP0136490B1 (de) 1990-03-21
WO1985000829A1 (en) 1985-02-28
DE3481716D1 (de) 1990-04-26
US4710473A (en) 1987-12-01
IL72642A0 (en) 1984-11-30
JPS60501988A (ja) 1985-11-21

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