IL71243A - 1,3-dihydro-3,3-disubstituted-6-methylfuro(3,4-c)pyridin-7-ol derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1,3-dihydro-3,3-disubstituted-6-methylfuro(3,4-c)pyridin-7-ol derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL71243A
IL71243A IL71243A IL7124384A IL71243A IL 71243 A IL71243 A IL 71243A IL 71243 A IL71243 A IL 71243A IL 7124384 A IL7124384 A IL 7124384A IL 71243 A IL71243 A IL 71243A
Authority
IL
Israel
Prior art keywords
methylfuro
disubstituted
pyridin
dihydro
derivatives
Prior art date
Application number
IL71243A
Other languages
English (en)
Other versions
IL71243A0 (en
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838327815A external-priority patent/GB8327815D0/en
Application filed by Scras filed Critical Scras
Publication of IL71243A0 publication Critical patent/IL71243A0/xx
Publication of IL71243A publication Critical patent/IL71243A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL71243A 1983-04-05 1984-03-14 1,3-dihydro-3,3-disubstituted-6-methylfuro(3,4-c)pyridin-7-ol derivatives,their preparation and pharmaceutical compositions containing them IL71243A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8309165 1983-04-05
GB838327815A GB8327815D0 (en) 1983-10-18 1983-10-18 Furo-(3 4-c)-pyridine derivatives

Publications (2)

Publication Number Publication Date
IL71243A0 IL71243A0 (en) 1984-06-29
IL71243A true IL71243A (en) 1987-12-20

Family

ID=26285725

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71243A IL71243A (en) 1983-04-05 1984-03-14 1,3-dihydro-3,3-disubstituted-6-methylfuro(3,4-c)pyridin-7-ol derivatives,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country Link
US (1) US4581363A (fr)
JP (1) JPS59193888A (fr)
KR (1) KR900005518B1 (fr)
AU (1) AU582113B2 (fr)
CA (1) CA1257269A (fr)
CH (1) CH660191A5 (fr)
DE (1) DE3412885C2 (fr)
DK (1) DK157931C (fr)
DZ (1) DZ629A1 (fr)
EG (1) EG18150A (fr)
ES (1) ES531285A0 (fr)
FI (1) FI76804C (fr)
FR (2) FR2543829B1 (fr)
GR (1) GR79577B (fr)
HK (1) HK11187A (fr)
IE (1) IE57424B1 (fr)
IL (1) IL71243A (fr)
IN (1) IN160104B (fr)
IT (1) IT1173770B (fr)
LU (1) LU85262A1 (fr)
MA (1) MA20084A1 (fr)
MX (1) MX167397B (fr)
MY (1) MY8600664A (fr)
NL (1) NL190328C (fr)
NO (1) NO161802C (fr)
NZ (1) NZ207552A (fr)
OA (1) OA07699A (fr)
PT (1) PT78361B (fr)
SE (1) SE458362B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3990349T1 (de) * 1988-04-06 1990-04-26 Scras Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
EP1169322B8 (fr) 1999-03-08 2006-09-13 Medicure Inc. Analogues de pyridoxal destines aux troubles provoques par une carence en vitamine b6
AU5840200A (en) 1999-07-13 2001-01-30 Medicure Inc. Treatment of diabetes and related pathologies
EP1872797A3 (fr) 1999-08-24 2008-04-02 Medicure International Inc. Traitement des pathologies cardiovasculaires et associées
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
WO2001064692A1 (fr) 2000-02-29 2001-09-07 Medicure International Inc. Phosphonates et malonates cardioprotecteurs
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US6897228B2 (en) * 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
ATE364595T1 (de) 2000-07-07 2007-07-15 Medicure Int Inc Pyridoxin- und pyridoxalanaloga als cardiovasculäre therapeutika
US20040121988A1 (en) * 2001-03-28 2004-06-24 Medicure International Inc. Treatment of cerebrovascular disease
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
JP2008505126A (ja) * 2004-07-07 2008-02-21 メディキュア インターナショナル インコーポレイテッド 血小板凝集薬を用いる併用療法
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
CA2585165A1 (fr) * 2004-10-28 2006-05-18 Medicure International Inc. Analogues de pyridoxine a double activite anti-plaquettes et anti-coagulantes
CA2632090A1 (fr) * 2005-11-28 2007-05-31 Medicure International Inc. Dosage selectionne pour le traitement de pathologies cardiovasculaires et apparentees

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
GB2008582B (en) * 1977-11-25 1982-04-28 Scras Pyridine derivative
IN156817B (fr) * 1981-02-10 1985-11-09 Scras

Also Published As

Publication number Publication date
NO841322L (no) 1984-10-08
IT1173770B (it) 1987-06-24
ES8601998A1 (es) 1985-11-01
PT78361A (en) 1984-05-01
IT8420396A0 (it) 1984-04-05
SE458362B (sv) 1989-03-20
IE840826L (en) 1984-10-05
DK157931C (da) 1990-08-27
DK178084D0 (da) 1984-04-04
LU85262A1 (fr) 1984-10-24
US4581363A (en) 1986-04-08
FR2543956B1 (fr) 1986-07-04
IL71243A0 (en) 1984-06-29
KR840008651A (ko) 1984-12-17
CH660191A5 (fr) 1987-03-31
ES531285A0 (es) 1985-11-01
IN160104B (fr) 1987-06-27
NL190328C (nl) 1994-01-17
NL190328B (nl) 1993-08-16
FR2543829B1 (fr) 1986-11-21
JPS59193888A (ja) 1984-11-02
MX167397B (es) 1993-03-22
FR2543829A1 (fr) 1984-10-12
MY8600664A (en) 1986-12-31
FI841273A0 (fi) 1984-03-30
DK178084A (da) 1984-10-06
SE8401841L (sv) 1984-10-06
JPH0556353B2 (fr) 1993-08-19
HK11187A (en) 1987-02-13
DK157931B (da) 1990-03-05
FI76804C (fi) 1988-12-12
NO161802B (no) 1989-06-19
IE57424B1 (en) 1992-09-09
FR2543956A1 (fr) 1984-10-12
KR900005518B1 (ko) 1990-07-30
CA1257269A (fr) 1989-07-11
MA20084A1 (fr) 1984-12-31
AU2640184A (en) 1984-10-11
NZ207552A (en) 1986-05-09
DZ629A1 (fr) 2004-09-13
SE8401841D0 (sv) 1984-04-03
FI841273A (fi) 1984-10-06
GR79577B (fr) 1984-10-30
OA07699A (fr) 1985-08-30
AU582113B2 (en) 1989-03-16
DE3412885C2 (de) 1990-10-04
NL8401013A (nl) 1984-11-01
EG18150A (en) 1992-08-30
FI76804B (fi) 1988-08-31
PT78361B (en) 1986-05-28
DE3412885A1 (de) 1984-10-11
NO161802C (no) 1989-09-27

Similar Documents

Publication Publication Date Title
IL71243A (en) 1,3-dihydro-3,3-disubstituted-6-methylfuro(3,4-c)pyridin-7-ol derivatives,their preparation and pharmaceutical compositions containing them
IL64759A0 (en) Furo-(3,4-c)pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL73706A0 (en) 2,2'-iminobisethanol derivatives,their preparation and pharmaceutical compositions containing them
IL76405A0 (en) 1,3-diacyl-2-oxyindole derivatives,their preparation and pharmaceutical compositions containing them
ZA848130B (en) New 6-vinyl-furo-(3,4-c)-pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL70756A (en) 3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL72151A0 (en) Tetrahydropyridazinone derivatives,their preparation and pharmaceutical compositions containing them
IL71633A (en) Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL71481A (en) Substituted 3h-indeno(1,2-c)-pyridazin-3-one(thiones),their preparation and pharmaceutical compositions containing them
IL70755A (en) 3-amino-4-cyano-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
ZA848826B (en) Milbemycin 5-carbonate derivatives,their preparations and compositions containing them
IL73222A0 (en) Benzenesulfonyl-lactam derivatives,their preparation and pharmaceutical compositions containing them
IL67155A (en) Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL72070A0 (en) 2-sulfamoylbenzo c(b)thiophene derivatives,their preparation and pharmaceutical compositions containing them
IL68496A0 (en) Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL73810A (en) 4,5,6,7-tetrahydrothiazolo-(5,4-c)pyridine derivatives,their preparation and pharmaceutical compositions containing them
EP0159652A3 (en) 4-phenylphthalazine derivatives, their preparation and pharmaceutical compositions containing them
DE3561808D1 (en) Phenylnonatetraenic-acid derivatives, their preparation and pharmaceutical compositions containing them
IL73278A0 (en) Pharmaceutical compositions containing 1,2-dithiolan derivatives,certain such derivatives and their preparation
IL73776A (en) N-phenyl-1h-tetrazole-5-carboxamide derivatives,their preparation and pharmaceutical compositions containing them
IL73231A0 (en) 1-acetylaminophenyl-2-amino-propanone derivatives,their preparation and pharmaceutical compositions containing them
IL62519A0 (en) Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL73429A (en) Tricyclic thiadiazinone derivatives,their preparation and pharmaceutical compositions containing them
IL76619A0 (en) Thieno-and furo(2,3-c)pyrrole derivatives,their preparation and pharmaceutical compositions containing them
GB2151226B (en) 2, 6-dioxopiperidine derivatives, their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees