IL70488A - 7(2-(difluoromethylthio)-acetylamino)-7-methoxy-3-tetrazolyl-thiomethyl-1-dethia-1-oxacephalosporins,processes for the preparation thereof and pharmaceutical and veterinary compositions containing the same - Google Patents
7(2-(difluoromethylthio)-acetylamino)-7-methoxy-3-tetrazolyl-thiomethyl-1-dethia-1-oxacephalosporins,processes for the preparation thereof and pharmaceutical and veterinary compositions containing the sameInfo
- Publication number
- IL70488A IL70488A IL70488A IL7048883A IL70488A IL 70488 A IL70488 A IL 70488A IL 70488 A IL70488 A IL 70488A IL 7048883 A IL7048883 A IL 7048883A IL 70488 A IL70488 A IL 70488A
- Authority
- IL
- Israel
- Prior art keywords
- oxacephalosporins
- dethia
- difluoromethylthio
- thiomethyl
- acetylamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57234472A JPS59139385A (ja) | 1982-12-23 | 1982-12-23 | フルオロメチルチオオキサセフアロスポリン |
Publications (2)
Publication Number | Publication Date |
---|---|
IL70488A0 IL70488A0 (en) | 1984-03-30 |
IL70488A true IL70488A (en) | 1988-03-31 |
Family
ID=16971542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL70488A IL70488A (en) | 1982-12-23 | 1983-12-20 | 7(2-(difluoromethylthio)-acetylamino)-7-methoxy-3-tetrazolyl-thiomethyl-1-dethia-1-oxacephalosporins,processes for the preparation thereof and pharmaceutical and veterinary compositions containing the same |
Country Status (26)
Country | Link |
---|---|
US (1) | US4532233A (pt) |
JP (1) | JPS59139385A (pt) |
KR (1) | KR890000095B1 (pt) |
AT (1) | AT383807B (pt) |
AU (1) | AU558547B2 (pt) |
BE (1) | BE898541A (pt) |
CA (1) | CA1236099A (pt) |
CH (1) | CH656619A5 (pt) |
DE (1) | DE3345989A1 (pt) |
DK (1) | DK159447C (pt) |
ES (6) | ES527595A0 (pt) |
FI (1) | FI74016C (pt) |
FR (1) | FR2538391B1 (pt) |
GB (1) | GB2132198B (pt) |
HK (1) | HK89988A (pt) |
HU (1) | HU189014B (pt) |
IE (1) | IE56401B1 (pt) |
IL (1) | IL70488A (pt) |
IT (1) | IT1160238B (pt) |
NL (1) | NL192740C (pt) |
NO (1) | NO167740C (pt) |
NZ (1) | NZ206413A (pt) |
PH (1) | PH19352A (pt) |
PT (1) | PT77831B (pt) |
SE (2) | SE461527B (pt) |
ZA (1) | ZA838920B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6045514A (ja) * | 1983-08-22 | 1985-03-12 | Shionogi & Co Ltd | 安定な抗菌性凍結乾燥製剤 |
JP2004168775A (ja) * | 2002-11-08 | 2004-06-17 | Orchid Chemicals & Pharmaceuticals Ltd | オキサセファロスポリンの改良合成法 |
CN101440098B (zh) * | 2004-02-20 | 2011-07-13 | 盐野义制药株式会社 | 氧头孢烯晶体 |
JP2009530268A (ja) * | 2006-03-15 | 2009-08-27 | カルテージア, エッセ ア エッセ ディ エマヌエーラ ミリアヴァッカ エ コンパニーア | (1−オキサ−又は1−チア−)3−セフェム誘導体及び関連する中間体の調製方法 |
CN102952149B (zh) * | 2012-11-09 | 2015-06-24 | 浙江新和成股份有限公司 | 一种氟氧头孢中间体的一锅合成法 |
KR101314500B1 (ko) * | 2012-12-28 | 2013-10-07 | 제일약품주식회사 | 안정성이 개선된 옥사세펨 제제 및 그 제조방법 |
CN103524534B (zh) * | 2013-09-02 | 2016-08-17 | 上海龙翔生物医药开发有限公司 | 氟氧头孢钠的制备方法 |
CN104327100B (zh) * | 2014-09-30 | 2016-09-28 | 华北制药河北华民药业有限责任公司 | 高纯度氟氧头孢钠制备工艺 |
CN105399755B (zh) * | 2015-11-03 | 2018-05-11 | 浙江永宁药业股份有限公司 | 一种氟氧头孢酸的合成方法 |
CN105801601B (zh) * | 2016-04-02 | 2018-01-26 | 丽珠医药集团股份有限公司 | 一种氟氧头孢钠合成方法 |
CN108424418A (zh) * | 2017-02-15 | 2018-08-21 | 山东致纯医药科技有限公司 | 一种氟氧头孢钠杂质 |
KR102115644B1 (ko) * | 2017-09-13 | 2020-05-27 | 주식회사 동도물산 | 7α-알콕시옥사세펨 중간체의 제조방법 |
CN110028522A (zh) * | 2019-04-22 | 2019-07-19 | 山西千岫制药有限公司 | 一种氟氧头孢母核的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5419990A (en) * | 1977-07-14 | 1979-02-15 | Shionogi & Co Ltd | Dihydrotriazinylthioxacephalosporin |
JPS5690088A (en) * | 1979-11-02 | 1981-07-21 | Meiji Seika Kaisha Ltd | Novel cephalosporin analog compound |
JPS56103185A (en) * | 1980-01-22 | 1981-08-18 | Shionogi & Co Ltd | Malonamidoxa-dethia-cephem compound |
-
1982
- 1982-12-23 JP JP57234472A patent/JPS59139385A/ja active Granted
-
1983
- 1983-11-28 ES ES527595A patent/ES527595A0/es active Granted
- 1983-11-28 NZ NZ206413A patent/NZ206413A/en unknown
- 1983-11-30 ZA ZA838920A patent/ZA838920B/xx unknown
- 1983-12-06 AU AU22113/83A patent/AU558547B2/en not_active Expired
- 1983-12-13 GB GB08333186A patent/GB2132198B/en not_active Expired
- 1983-12-14 IE IE2951/83A patent/IE56401B1/en not_active IP Right Cessation
- 1983-12-15 PT PT77831A patent/PT77831B/pt unknown
- 1983-12-16 FR FR8320221A patent/FR2538391B1/fr not_active Expired
- 1983-12-19 FI FI834682A patent/FI74016C/fi not_active IP Right Cessation
- 1983-12-20 CA CA000443807A patent/CA1236099A/en not_active Expired
- 1983-12-20 DE DE3345989A patent/DE3345989A1/de active Granted
- 1983-12-20 IL IL70488A patent/IL70488A/xx not_active IP Right Cessation
- 1983-12-21 NO NO834729A patent/NO167740C/no unknown
- 1983-12-21 AT AT0446883A patent/AT383807B/de not_active IP Right Cessation
- 1983-12-21 SE SE8307079A patent/SE461527B/sv not_active IP Right Cessation
- 1983-12-21 DK DK589583A patent/DK159447C/da not_active IP Right Cessation
- 1983-12-22 IT IT68343/83A patent/IT1160238B/it active
- 1983-12-22 HU HU834424A patent/HU189014B/hu unknown
- 1983-12-22 PH PH30022A patent/PH19352A/en unknown
- 1983-12-22 BE BE0/212107A patent/BE898541A/fr not_active IP Right Cessation
- 1983-12-22 US US06/564,553 patent/US4532233A/en not_active Expired - Lifetime
- 1983-12-22 NL NL8304409A patent/NL192740C/nl not_active IP Right Cessation
- 1983-12-23 KR KR1019830006137A patent/KR890000095B1/ko not_active IP Right Cessation
- 1983-12-23 CH CH6917/83A patent/CH656619A5/de not_active IP Right Cessation
-
1984
- 1984-07-13 ES ES534291A patent/ES8703458A1/es not_active Expired
- 1984-07-13 ES ES534289A patent/ES534289A0/es active Granted
- 1984-07-13 ES ES534290A patent/ES534290A0/es active Granted
- 1984-07-13 ES ES534288A patent/ES534288A0/es active Granted
-
1986
- 1986-07-01 ES ES556846A patent/ES8708227A1/es not_active Expired
-
1988
- 1988-05-30 SE SE8802008A patent/SE470132B/sv not_active IP Right Cessation
- 1988-11-03 HK HK899/88A patent/HK89988A/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |