IL66890A - 7-bromo-5-(2-halophenyl)-1h-2,3-dihydro-1,4-benzodiazepines,their manufacture and pharmaceutical compositions containing them - Google Patents
7-bromo-5-(2-halophenyl)-1h-2,3-dihydro-1,4-benzodiazepines,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL66890A IL66890A IL66890A IL6689082A IL66890A IL 66890 A IL66890 A IL 66890A IL 66890 A IL66890 A IL 66890A IL 6689082 A IL6689082 A IL 6689082A IL 66890 A IL66890 A IL 66890A
- Authority
- IL
- Israel
- Prior art keywords
- halophenyl
- benzodiazepines
- dihydro
- bromo
- manufacture
- Prior art date
Links
- 229940049706 benzodiazepine Drugs 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000002539 anti-aggressive effect Effects 0.000 abstract 1
- 125000004069 aziridinyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 230000001003 psychopharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
- C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813138769 DE3138769A1 (de) | 1981-09-30 | 1981-09-30 | 7-brom-5-(2-halogenphenyl)-1h-2,3-dihydro-1,4- benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL66890A0 IL66890A0 (en) | 1982-12-31 |
| IL66890A true IL66890A (en) | 1985-11-29 |
Family
ID=6142952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL66890A IL66890A (en) | 1981-09-30 | 1982-09-29 | 7-bromo-5-(2-halophenyl)-1h-2,3-dihydro-1,4-benzodiazepines,their manufacture and pharmaceutical compositions containing them |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4505908A (cs) |
| EP (1) | EP0075855B1 (cs) |
| JP (1) | JPS5867678A (cs) |
| AT (1) | ATE17123T1 (cs) |
| AU (1) | AU553689B2 (cs) |
| CA (1) | CA1196635A (cs) |
| DD (1) | DD203907A5 (cs) |
| DE (2) | DE3138769A1 (cs) |
| DK (1) | DK156065C (cs) |
| ES (1) | ES8306126A1 (cs) |
| FI (1) | FI68047C (cs) |
| GR (1) | GR77652B (cs) |
| HU (1) | HU189179B (cs) |
| IE (1) | IE53937B1 (cs) |
| IL (1) | IL66890A (cs) |
| NO (1) | NO157698C (cs) |
| NZ (1) | NZ202036A (cs) |
| PH (1) | PH18102A (cs) |
| PT (1) | PT75553B (cs) |
| ZA (1) | ZA827140B (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3221402A1 (de) * | 1982-06-05 | 1983-12-08 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 5-phenyl-1,4-benzodiazepine enthaltende analgetisch wirksame pharmazeutische zubereitungen |
| US6818607B1 (en) | 1999-08-27 | 2004-11-16 | Procter & Gamble Company | Bleach boosting components, compositions and laundry methods |
| MXPA02002129A (es) * | 1999-08-27 | 2002-09-18 | Procter & Gamble | Componentes de formulacion de accion rapida, composiciones y metodos para lavanderia que los emplean. |
| US6821935B1 (en) | 1999-08-27 | 2004-11-23 | Procter & Gamble Company | Color safe laundry methods employing zwitterionic formulation components |
| US6903060B1 (en) | 1999-08-27 | 2005-06-07 | Procter & Gamble Company | Stable formulation components, compositions and laundry methods employing same |
| US7109156B1 (en) | 1999-08-27 | 2006-09-19 | Procter & Gamble Company | Controlled availability of formulation components, compositions and laundry methods employing same |
| ES2265966T3 (es) * | 1999-08-27 | 2007-03-01 | THE PROCTER & GAMBLE COMPANY | Componentes, composiciones y metodos de lavado de ropa que refuerzan el blanqueador. |
| US6825160B1 (en) | 1999-08-27 | 2004-11-30 | Procter & Gamble Company | Color safe laundry methods employing cationic formulation components |
| EP1206516A1 (en) | 1999-08-27 | 2002-05-22 | The Procter & Gamble Company | Stability enhancing formulation components, compositions and laundry methods employing same |
| US7169744B2 (en) * | 2002-06-06 | 2007-01-30 | Procter & Gamble Company | Organic catalyst with enhanced solubility |
| US7557076B2 (en) | 2002-06-06 | 2009-07-07 | The Procter & Gamble Company | Organic catalyst with enhanced enzyme compatibility |
| US20050113246A1 (en) * | 2003-11-06 | 2005-05-26 | The Procter & Gamble Company | Process of producing an organic catalyst |
| AR051659A1 (es) * | 2005-06-17 | 2007-01-31 | Procter & Gamble | Una composicion que comprende un catalizador organico con compatibilidada enzimatica mejorada |
| US9700443B2 (en) | 2015-06-12 | 2017-07-11 | Abbott Cardiovascular Systems Inc. | Methods for attaching a radiopaque marker to a scaffold |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2520937C3 (de) * | 1975-05-10 | 1978-10-12 | Kali-Chemie Ag, 3000 Hannover | 7-Brom-1 -methyl^-alkoxymethyl-S-(2-halogenphenyl)-lH-23-dihydro-l,4benzodiazepinderivate, deren Säureadditionssalze und pharmazeutische Präparate |
| DE2221558C2 (de) * | 1972-05-03 | 1982-12-02 | Kali-Chemie Ag, 3000 Hannover | 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4244869A (en) * | 1972-05-03 | 1981-01-13 | Kali-Chemie A.G. | Benzodiazepine derivatives and process of making them |
| DE2353160C2 (de) * | 1973-05-02 | 1986-07-17 | Kali-Chemie Ag, 3000 Hannover | 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine, ihre Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel |
-
1981
- 1981-09-30 DE DE19813138769 patent/DE3138769A1/de not_active Withdrawn
-
1982
- 1982-09-14 PT PT75553A patent/PT75553B/pt not_active IP Right Cessation
- 1982-09-17 ES ES515774A patent/ES8306126A1/es not_active Expired
- 1982-09-22 DE DE8282108758T patent/DE3268156D1/de not_active Expired
- 1982-09-22 AT AT82108758T patent/ATE17123T1/de not_active IP Right Cessation
- 1982-09-22 EP EP82108758A patent/EP0075855B1/de not_active Expired
- 1982-09-23 US US06/422,297 patent/US4505908A/en not_active Expired - Fee Related
- 1982-09-27 HU HU823099A patent/HU189179B/hu not_active IP Right Cessation
- 1982-09-27 DD DD82243528A patent/DD203907A5/de not_active IP Right Cessation
- 1982-09-28 GR GR69376A patent/GR77652B/el unknown
- 1982-09-28 NO NO823265A patent/NO157698C/no unknown
- 1982-09-28 JP JP57167729A patent/JPS5867678A/ja active Granted
- 1982-09-28 CA CA000412319A patent/CA1196635A/en not_active Expired
- 1982-09-29 AU AU88838/82A patent/AU553689B2/en not_active Ceased
- 1982-09-29 DK DK431782A patent/DK156065C/da not_active IP Right Cessation
- 1982-09-29 IE IE2362/82A patent/IE53937B1/en not_active IP Right Cessation
- 1982-09-29 PH PH27925A patent/PH18102A/en unknown
- 1982-09-29 ZA ZA827140A patent/ZA827140B/xx unknown
- 1982-09-29 NZ NZ202036A patent/NZ202036A/en unknown
- 1982-09-29 FI FI823338A patent/FI68047C/fi not_active IP Right Cessation
- 1982-09-29 IL IL66890A patent/IL66890A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT75553B (en) | 1984-12-12 |
| CA1196635A (en) | 1985-11-12 |
| NO157698C (no) | 1988-05-04 |
| EP0075855A2 (de) | 1983-04-06 |
| FI823338A0 (fi) | 1982-09-29 |
| DE3138769A1 (de) | 1983-04-14 |
| PH18102A (en) | 1985-03-20 |
| ES515774A0 (es) | 1983-05-01 |
| DK156065C (da) | 1989-11-13 |
| DK431782A (da) | 1983-03-31 |
| FI68047C (fi) | 1985-07-10 |
| DD203907A5 (de) | 1983-11-09 |
| IE822362L (en) | 1983-03-30 |
| FI823338L (fi) | 1983-03-31 |
| DE3268156D1 (en) | 1986-02-06 |
| US4505908A (en) | 1985-03-19 |
| HU189179B (en) | 1986-06-30 |
| JPS5867678A (ja) | 1983-04-22 |
| ES8306126A1 (es) | 1983-05-01 |
| FI68047B (fi) | 1985-03-29 |
| NO823265L (no) | 1983-04-05 |
| IE53937B1 (en) | 1989-04-26 |
| GR77652B (cs) | 1984-09-25 |
| IL66890A0 (en) | 1982-12-31 |
| PT75553A (en) | 1982-10-01 |
| ATE17123T1 (de) | 1986-01-15 |
| DK156065B (da) | 1989-06-19 |
| ZA827140B (en) | 1983-07-27 |
| AU553689B2 (en) | 1986-07-24 |
| NZ202036A (en) | 1985-02-28 |
| AU8883882A (en) | 1983-04-14 |
| EP0075855A3 (en) | 1983-06-15 |
| EP0075855B1 (de) | 1985-12-27 |
| NO157698B (no) | 1988-01-25 |
| JPH0433791B2 (cs) | 1992-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL66890A (en) | 7-bromo-5-(2-halophenyl)-1h-2,3-dihydro-1,4-benzodiazepines,their manufacture and pharmaceutical compositions containing them | |
| EP0551963A3 (en) | Use of heterocyclic derivatives for the manufacture of medicaments | |
| NO303015B1 (no) | AnalogifremgangsmÕte for fremstilling av terapeutisk aktive 4-alkylimidazolderivater | |
| DE3576075D1 (de) | 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel. | |
| NZ217418A (en) | Tricyclic heterocyclic compounds and pharmaceutical compositions | |
| IL66835A (en) | 1,4-disubstituted(1,2,4)triazolo(4,3-alpha)quinazolin-5(4h)-one derivatives and their salts,their preparation and pharmaceutical compositions containing them | |
| DE58907706D1 (de) | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepine, ihre Herstellung und ihre Verwendung als Arzneimittel. | |
| ZA874385B (en) | Hydroxypyrazole derivatives,their preparation and their use against microorganism | |
| FI961246A0 (fi) | Radiofarmaseutika preparationer av radiojoderade bentsodiatsepinanaloger och deras anvaendning i diaknostik | |
| AU551901B2 (en) | Substituted thienobenzodiazepinones | |
| BE896635A (fr) | Compositions pharmaceutiques analgesiques contenant des 5-phenyl-1,4-benzodiazepines. | |
| JPS57192370A (en) | 5,6-dihydro-11-alkylene-morphanthridin-6-one, manufacture and medicine containing same | |
| ES8200890A1 (es) | Procedimiento para preparar benzodiazepinas | |
| IL95384A0 (en) | 1,3-oxazines,their preparation and pharmaceutical compositions containing them | |
| IL82419A (en) | 3-amino-dihydropyridines,their preparation and medicaments containing them | |
| PH17809A (en) | New delta-pyrroline thiolactam ethers and a process for their preparation | |
| ES8301991A1 (es) | Procedimiento para la preparacion de 7-(2,6-dibromo-4-metil-fenil)-2,3-dihidro-imidazo 1,2-a, imidazoles. | |
| SE8704331D0 (sv) | Condensed cyclic triazole derivatives | |
| FR2199991A1 (en) | Hydrophilic 1,4-benzodiazepin-2-one derivs - by reaction of benzodiazepinone and haloalkanoylalkanes and deprotection, with sedative, muscle-relaxant and anticonvulsive action | |
| IT1270689B (it) | "derivati benzossazinonici e benzotiazinonici e loro uso terapeutico" |