ES2007745A6 - Proceddimiento de preparacion de nuevos derivados triazoles ciclicos condensados. - Google Patents

Proceddimiento de preparacion de nuevos derivados triazoles ciclicos condensados.

Info

Publication number
ES2007745A6
ES2007745A6 ES8703167A ES8703167A ES2007745A6 ES 2007745 A6 ES2007745 A6 ES 2007745A6 ES 8703167 A ES8703167 A ES 8703167A ES 8703167 A ES8703167 A ES 8703167A ES 2007745 A6 ES2007745 A6 ES 2007745A6
Authority
ES
Spain
Prior art keywords
triazole derivatives
condensed cyclic
pharmaceutical compositions
cyclic triazole
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8703167A
Other languages
English (en)
Inventor
Jozsef Reiter
Endre Rivo
Klara Reiter
Marton Fekete
Frigyes Gorgenyi
Lujza Petocz
Istvan Gacsalyi
Frigyes Gyertyan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES2007745A6 publication Critical patent/ES2007745A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS TRIAZOLES CICLICOS CONDENSADOS. LA INVENCION SE RELACIONA CON UNA FAMILIA DE TRIAZOLES CICLICOS DE FORMULA GENERAL (I), EN LA QUE Q1 ES HIDROGENO, MORFOLINO O AMINO SUSTITUIDO, INCLUSO HETEROCICLICO. Q2 ES UN GRIPO ALQUILAMINO SUSTITUIDO, INCLUSO HETEROCICLICO, X E Y REPRESENTAN F 0O F H2, Y E Y Z REPRESENTAN METILENO O UN RADICAL AMINO SEC O TERCIARIO, CUYO PROCEDIMIENTO DE PREPARACION INCLUYE LA REACCION DE UN 5-AMINO TRIAZOL DE FORMULA GENERAL (II) CON UNA 3-CARBETOXI PIPERIDONA DE FORMULA GENERAL (III), HACIENDO REACCIONAR EL COMPUESTO ASI OBTENIDO CON REACTIVOS ISOCIONOS O HALOGENUROS DE ACIDO O DERIVADOS HALOGENADOS SEGUN EL CASO. LOS COMPUESTOS DESCRITOS POSEEN UTILES PROPIEDADES SEDANTES Y TRANQUILIZANTES Y PRODUCEN PARTICULARMENTE EFECTOS ESPASMOLITICOS, INHIBIDORES DE LA MOTALIDAD, POTENCIADORES DE LA NARCOSIS Y DE LA YOHIMBINA, ANESTESIADORESLOCALES Y ASIMISMO INHIBIDORES DE LA PTOSIS PRODUCIDA POR LA RESERPINA.
ES8703167A 1986-11-05 1987-11-05 Proceddimiento de preparacion de nuevos derivados triazoles ciclicos condensados. Expired ES2007745A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU864602A HU198484B (en) 1986-11-05 1986-11-05 Process for producing new condensed cyclic triazolo/1,5-a/pyrimidine derivatives

Publications (1)

Publication Number Publication Date
ES2007745A6 true ES2007745A6 (es) 1989-07-01

Family

ID=10968423

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8703167A Expired ES2007745A6 (es) 1986-11-05 1987-11-05 Proceddimiento de preparacion de nuevos derivados triazoles ciclicos condensados.

Country Status (23)

Country Link
US (1) US4831029A (es)
JP (1) JPH01258675A (es)
KR (1) KR880006242A (es)
CN (1) CN87107643A (es)
AU (1) AU8082087A (es)
BE (1) BE1002422A4 (es)
CS (1) CS788487A2 (es)
DD (1) DD273259A5 (es)
DE (1) DE3737610A1 (es)
DK (1) DK579587A (es)
ES (1) ES2007745A6 (es)
FI (1) FI874885A (es)
FR (1) FR2606017A1 (es)
GB (1) GB2197319A (es)
GR (1) GR871702B (es)
HU (1) HU198484B (es)
IL (1) IL84368A0 (es)
IT (1) IT1223346B (es)
NL (1) NL8702629A (es)
PL (1) PL268619A1 (es)
SE (1) SE8704331L (es)
YU (2) YU199887A (es)
ZA (1) ZA878312B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478825A (en) * 1991-02-22 1995-12-26 Egis Gyogyszergyar 5-(substituted amino)-1,2,4-triazolo (1,5-A) pyrimidine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444607A (en) * 1945-12-15 1948-07-06 Gen Aniline & Film Corp Stabilizers for photographic emulsions
DE1670375A1 (de) * 1966-08-12 1970-11-05 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des s-Triazolo-[1,5]-chinazolins
EP0181282A1 (de) * 1984-10-01 1986-05-14 Ciba-Geigy Ag Triazolochinazolinverbindungen

Also Published As

Publication number Publication date
HUT47574A (en) 1989-03-28
AU8082087A (en) 1988-05-12
CS788487A2 (en) 1989-11-14
ZA878312B (en) 1988-09-28
FR2606017A1 (fr) 1988-05-06
FI874885A0 (fi) 1987-11-04
DE3737610A1 (de) 1988-05-11
IL84368A0 (en) 1988-04-29
YU199888A (en) 1989-02-28
DK579587A (da) 1988-05-06
DK579587D0 (da) 1987-11-04
HU198484B (en) 1989-10-30
PL268619A1 (en) 1988-09-01
SE8704331D0 (sv) 1987-11-05
BE1002422A4 (fr) 1991-02-05
YU199887A (en) 1989-02-28
IT8722511A0 (it) 1987-11-04
DD273259A5 (de) 1989-11-08
FI874885A (fi) 1988-05-06
KR880006242A (ko) 1988-07-22
SE8704331L (sv) 1988-05-06
CN87107643A (zh) 1988-08-24
IT1223346B (it) 1990-09-19
GB8725997D0 (en) 1987-12-09
NL8702629A (nl) 1988-06-01
GR871702B (en) 1988-03-04
GB2197319A (en) 1988-05-18
US4831029A (en) 1989-05-16
JPH01258675A (ja) 1989-10-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402