ES8605819A1 - Procedimiento de preparacion de nuevos derivados nucleosidos. - Google Patents
Procedimiento de preparacion de nuevos derivados nucleosidos.Info
- Publication number
- ES8605819A1 ES8605819A1 ES547820A ES547820A ES8605819A1 ES 8605819 A1 ES8605819 A1 ES 8605819A1 ES 547820 A ES547820 A ES 547820A ES 547820 A ES547820 A ES 547820A ES 8605819 A1 ES8605819 A1 ES 8605819A1
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- nucleoside derivatives
- compounds
- formula
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS NUCLEOSIDOS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER DERIVADOS NUCLEOSIDOS DE FORMULA (I) DONDE R Y R SON IGUALES O DIFERENTES Y REPRESENTAN H O UN ACILO OPTATIVAMENTE SUSTITUIDO, ALCANOILO DE CADENA RECTA O RAMIFICADA OPTATIVAMENTE SUSTITUIDO, AROILO OPTATIVAMENTE SUSTITUIDO O HETEROAROILO OPTATIVAMENTE SUSTITUIDO; DONDE OPTATIVAMENTE SE PUEDEN EFECTUAR UNA DE LAS REACCIONES: A) ACILACION DE UN COMPUESTO DE FORMULA (I) CON UN COMPUESTO DE FORMULAS Y-CL O (IV); B) DESACILACION DEL COMPUESTO DE FORMULA (I) CON AMONIACO; Y C) INTRODUCIR UN GRUPO BLOQUEADOR EN EL COMPUESTO DE FORMULA (I). TIENEN UTILIDAD POR INHIBIR LA MULTIPLICACION VIRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU843821A HU192472B (en) | 1984-10-12 | 1984-10-12 | Process for preparing /e/-5-/2-bromo-vinyl/-uracyl derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8605819A1 true ES8605819A1 (es) | 1986-04-01 |
ES547820A0 ES547820A0 (es) | 1986-04-01 |
Family
ID=10965655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547820A Expired ES8605819A1 (es) | 1984-10-12 | 1985-10-11 | Procedimiento de preparacion de nuevos derivados nucleosidos. |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS61126097A (es) |
KR (1) | KR870001935B1 (es) |
AT (1) | ATA294685A (es) |
BE (1) | BE903381A (es) |
DD (1) | DD239595A5 (es) |
DE (1) | DE3536604A1 (es) |
DK (1) | DK465585A (es) |
ES (1) | ES8605819A1 (es) |
FI (1) | FI853969L (es) |
FR (1) | FR2571726A1 (es) |
GB (1) | GB2165539A (es) |
HU (1) | HU192472B (es) |
IL (1) | IL76661A0 (es) |
IT (1) | IT1186775B (es) |
NL (1) | NL8502794A (es) |
NO (1) | NO854041L (es) |
PL (1) | PL255741A1 (es) |
SE (1) | SE8504708L (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8912972D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Therapeutic nucleosides |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5136498A (ja) * | 1974-09-20 | 1976-03-27 | Tanabe Seiyaku Co | 2*2**anhidoroarabinofuranoshirurashirujudotainoseiho |
JPS5687599A (en) * | 1979-12-19 | 1981-07-16 | Yamasa Shoyu Co Ltd | E 55 22halogenovinyl arabinofuranosyluracil and its preparation |
NZ199764A (en) * | 1981-03-20 | 1984-08-24 | Beecham Group Plc | 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions |
-
1984
- 1984-10-12 HU HU843821A patent/HU192472B/hu not_active IP Right Cessation
-
1985
- 1985-10-07 BE BE1/011346A patent/BE903381A/fr not_active IP Right Cessation
- 1985-10-10 FR FR8515026A patent/FR2571726A1/fr not_active Withdrawn
- 1985-10-11 KR KR1019850007493A patent/KR870001935B1/ko active IP Right Grant
- 1985-10-11 IL IL76661A patent/IL76661A0/xx unknown
- 1985-10-11 GB GB08525152A patent/GB2165539A/en not_active Withdrawn
- 1985-10-11 NO NO854041A patent/NO854041L/no unknown
- 1985-10-11 IT IT22442/85A patent/IT1186775B/it active
- 1985-10-11 PL PL25574185A patent/PL255741A1/xx unknown
- 1985-10-11 AT AT852946A patent/ATA294685A/de not_active Application Discontinuation
- 1985-10-11 DK DK465585A patent/DK465585A/da not_active Application Discontinuation
- 1985-10-11 JP JP60226674A patent/JPS61126097A/ja active Pending
- 1985-10-11 FI FI853969A patent/FI853969L/fi not_active Application Discontinuation
- 1985-10-11 DD DD85281660A patent/DD239595A5/de unknown
- 1985-10-11 NL NL8502794A patent/NL8502794A/nl not_active Application Discontinuation
- 1985-10-11 ES ES547820A patent/ES8605819A1/es not_active Expired
- 1985-10-11 SE SE8504708A patent/SE8504708L/xx not_active Application Discontinuation
- 1985-10-14 DE DE19853536604 patent/DE3536604A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE3536604A1 (de) | 1986-04-17 |
GB8525152D0 (en) | 1985-11-13 |
HU192472B (en) | 1987-06-29 |
KR870001935B1 (ko) | 1987-10-22 |
NL8502794A (nl) | 1986-05-01 |
DD239595A5 (de) | 1986-10-01 |
SE8504708L (sv) | 1986-04-13 |
JPS61126097A (ja) | 1986-06-13 |
IT8522442A0 (it) | 1985-10-11 |
GB2165539A (en) | 1986-04-16 |
FI853969L (fi) | 1986-04-13 |
IT1186775B (it) | 1987-12-16 |
DK465585A (da) | 1986-04-13 |
BE903381A (fr) | 1986-04-07 |
FR2571726A1 (fr) | 1986-04-18 |
NO854041L (no) | 1986-04-14 |
SE8504708D0 (sv) | 1985-10-11 |
FI853969A0 (fi) | 1985-10-11 |
DK465585D0 (da) | 1985-10-11 |
IL76661A0 (en) | 1986-02-28 |
PL255741A1 (en) | 1986-08-12 |
KR860003270A (ko) | 1986-05-21 |
HUT38655A (en) | 1986-06-30 |
ES547820A0 (es) | 1986-04-01 |
ATA294685A (de) | 1987-03-15 |
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