|
JPS5899471A
(ja)
*
|
1981-12-07 |
1983-06-13 |
Tanabe Seiyaku Co Ltd |
ベンゾチアゼピン誘導体の新規製造法
|
|
US4940704A
(en)
*
|
1989-08-16 |
1990-07-10 |
Hoechst-Roussel Pharmaceutical Inc. |
Pyrido[3,4-b][1,4]benzoxazepines
|
|
DK0419861T3
(da)
*
|
1989-08-29 |
1996-03-04 |
Boehringer Ingelheim Pharma |
Anvendelse af dibenz(b,f) (1,4)oxazepin (og thiazepin)-11(10H)-oner og -thioner til fremstilling af farmaceutisk præparat til forebyggelse eller behandling af AIDS
|
|
GB9021813D0
(en)
*
|
1990-10-08 |
1990-11-21 |
Ici Plc |
Tricyclic heterocycles
|
|
US5212169A
(en)
*
|
1991-10-31 |
1993-05-18 |
G. D. Searle & Co. |
Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
|
|
US5304644A
(en)
*
|
1992-04-15 |
1994-04-19 |
G. D. Searle & Co. |
1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
|
|
US5449673A
(en)
*
|
1992-08-13 |
1995-09-12 |
G. D. Searle & Co. |
10,11-dihydro-10-(3-substituted-1-oxo-2-propyl, propenyl or propynyl)dibenz[b,f][1,4] oxazepine prostaglandin antagonists
|
|
US5395932A
(en)
*
|
1993-04-30 |
1995-03-07 |
G. D. Searle & Co. |
2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
|
|
US5354746A
(en)
*
|
1993-06-01 |
1994-10-11 |
G. D. Searle & Co. |
Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
|
|
US5461047A
(en)
*
|
1993-06-16 |
1995-10-24 |
G. D. Searle & Co. |
2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
|
|
US5354747A
(en)
*
|
1993-06-16 |
1994-10-11 |
G. D. Searle & Co. |
2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
|
|
US5420270A
(en)
*
|
1993-10-07 |
1995-05-30 |
G. D. Searle & Co. |
Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
|
|
US5424424A
(en)
*
|
1993-10-07 |
1995-06-13 |
G. D. Searle & Co. |
Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
|
|
US5488046A
(en)
*
|
1993-11-03 |
1996-01-30 |
G. D. Searle & Co. |
Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
|
|
US5441950A
(en)
*
|
1994-06-09 |
1995-08-15 |
G. D. Searle & Co. |
Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use
|
|
US5449675A
(en)
*
|
1994-06-09 |
1995-09-12 |
G. D. Searle & Co. |
Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use
|
|
US5698551A
(en)
*
|
1995-04-07 |
1997-12-16 |
Novo Nordisk A/S |
Heterocyclic compounds
|
|
AR040778A1
(es)
|
2002-08-06 |
2005-04-20 |
Glaxo Group Ltd |
Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
|
|
DE10242488A1
(de)
*
|
2002-09-13 |
2004-03-25 |
Bayer Ag |
Dibenzoxazeptine
|
|
GB0525662D0
(en)
|
2005-12-16 |
2006-01-25 |
Glaxo Group Ltd |
Immunoglobulins
|
|
TW201029662A
(en)
|
2008-12-19 |
2010-08-16 |
Glaxo Group Ltd |
Novel antigen binding proteins
|
|
WO2010115786A1
(en)
|
2009-04-01 |
2010-10-14 |
Glaxo Group Limited |
Anti-il-23 immunoglobulins
|
|
CA2787070A1
(en)
|
2010-01-28 |
2011-08-04 |
Ian Kirby |
Cd127 binding proteins
|
|
CN102834413A
(zh)
|
2010-02-09 |
2012-12-19 |
葛兰素集团有限公司 |
代谢障碍的治疗
|
|
UA108227C2
(xx)
|
2010-03-03 |
2015-04-10 |
|
Антигензв'язуючий білок
|
|
AR081556A1
(es)
|
2010-06-03 |
2012-10-03 |
Glaxo Group Ltd |
Proteinas de union al antigeno humanizadas
|
|
CN103201290B
(zh)
|
2010-06-14 |
2016-09-28 |
莱克拉生物医学股份公司 |
S100a4抗体及其治疗用途
|
|
MX351887B
(es)
|
2010-11-23 |
2017-11-01 |
Glaxo Group Ltd |
Proteinas de union a antigeno para oncostatina m (osm).
|
|
EP2691411B1
(de)
|
2011-03-29 |
2020-02-26 |
GlaxoSmithKline LLC |
Puffersystem zur proteinreinigung
|
|
BR112013025866A2
(pt)
|
2011-04-07 |
2016-12-20 |
Glaxosmithkline Llc |
formulações com viscosidade reduzida
|
|
EP2714737A1
(de)
|
2011-05-27 |
2014-04-09 |
Glaxo Group Limited |
Bcma (cd269/tnfrsf17)-bindende proteine
|
|
IN2014KN02952A
(de)
|
2012-07-05 |
2015-05-08 |
Glaxo Group Ltd |
|
|
HK1206073A1
(en)
|
2012-07-24 |
2015-12-31 |
药品循环有限责任公司 |
Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
|
|
BR122017017921A2
(pt)
|
2012-07-27 |
2019-09-10 |
Aragon Pharmaceuticals, Inc. |
métodos e sistema para determinar a resistência à terapia de receptor de androgênio
|
|
AU2014229282B2
(en)
|
2013-03-15 |
2017-02-02 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Low concentration antibody formulations
|
|
EP4371996A3
(de)
|
2013-03-15 |
2024-08-14 |
GlaxoSmithKline Intellectual Property Development Limited |
Verfahren zur aufreinigung von antikörpern
|
|
WO2014141149A1
(en)
|
2013-03-15 |
2014-09-18 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Formulations with reduced viscosity
|
|
US20160312179A1
(en)
|
2013-03-15 |
2016-10-27 |
Glaxosmithkline Intellechtual Property (No.2) Limited |
Use of tricarboxylic acid (tca) intermediates to control ammonia generation in cell culture
|
|
RS60538B1
(sr)
|
2013-03-15 |
2020-08-31 |
Glaxosmithkline Ip Dev Ltd |
Anti-lag-3 vezujući proteini
|
|
TWI694836B
(zh)
|
2014-05-16 |
2020-06-01 |
英商葛蘭素史克智慧財產管理有限公司 |
抗體調配物
|
|
WO2015200790A2
(en)
|
2014-06-26 |
2015-12-30 |
Yale University |
Compositions and methods to regulate renalase in the treatment of diseases and disorders
|
|
WO2016059602A2
(en)
|
2014-10-16 |
2016-04-21 |
Glaxo Group Limited |
Methods of treating cancer and related compositions
|
|
MA41414A
(fr)
|
2015-01-28 |
2017-12-05 |
Centre Nat Rech Scient |
Protéines de liaison agonistes d' icos
|
|
AU2016303550B2
(en)
|
2015-08-04 |
2019-06-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
EP3331917A1
(de)
|
2015-08-04 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationsbehandlungen sowie verwendungen und verfahren davon
|
|
WO2017021911A1
(en)
|
2015-08-04 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
BR112018002520A2
(pt)
|
2015-08-06 |
2018-09-18 |
Glaxosmithkline Ip Dev Ltd |
Agonistas de tlr4 e composições dos mesmos e seuuso no tratamento de câncer
|
|
WO2017021912A1
(en)
|
2015-08-06 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combined tlrs modulators with anti ox40 antibodies
|
|
TW201716084A
(zh)
|
2015-08-06 |
2017-05-16 |
葛蘭素史克智慧財產發展有限公司 |
組合物及其用途與治療
|
|
EP3331919A1
(de)
|
2015-08-07 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationstherapie mit anti-ctla-4-antikörpern
|
|
RU2760582C2
(ru)
|
2015-09-02 |
2021-11-29 |
Иммутеп С.А.С. |
Анти-LAG-3 антитела
|
|
ES2913208T3
(es)
|
2015-12-01 |
2022-06-01 |
Glaxosmithkline Ip Dev Ltd |
Tratamientos de combinación y usos y métodos de los mismos
|
|
EP3494140A1
(de)
|
2016-08-04 |
2019-06-12 |
GlaxoSmithKline Intellectual Property Development Ltd |
Anti-icos- und anti-pd-1-antikörper-kombinationstherapie
|
|
GB201614627D0
(en)
|
2016-08-30 |
2016-10-12 |
Glaxosmithkline Ip Dev Ltd |
Antigen binding proteins
|
|
RU2759909C2
(ru)
|
2016-09-07 |
2021-11-18 |
Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Способы очистки антител
|
|
WO2018100535A1
(en)
|
2016-12-01 |
2018-06-07 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
EP3548069A1
(de)
|
2016-12-01 |
2019-10-09 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationstherapie
|
|
EP3582855A1
(de)
|
2017-02-15 |
2019-12-25 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationstherapie zur behandlung von krebs
|
|
JP2020522555A
(ja)
|
2017-06-09 |
2020-07-30 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
組み合わせ療法
|
|
EP3635010A1
(de)
|
2017-06-09 |
2020-04-15 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationstherapie mit icos-agonist und ox40-agonisten zur behandlung von krebs
|
|
CA3066007A1
(en)
|
2017-06-09 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy with icos agonist and ox40 agonist to treat cancer
|
|
EP3692066A2
(de)
|
2017-09-14 |
2020-08-12 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationsbehandlung von krebs
|
|
WO2019106605A1
(en)
|
2017-12-01 |
2019-06-06 |
Board Of Regents, The University Of Texas System |
Combination treatment for cancer
|
|
TW202000891A
(zh)
|
2018-03-07 |
2020-01-01 |
英商葛蘭素史克智慧財產發展有限公司 |
純化抗體之方法
|
|
TW202003555A
(zh)
|
2018-03-07 |
2020-01-16 |
英商葛蘭素史克智慧財產發展有限公司 |
用於純化重組多肽之方法
|
|
JP7572006B2
(ja)
|
2018-05-25 |
2024-10-23 |
テンプル ユニヴァーシティ - オブ ザ コモンウェルス システム オブ ハイアー エデュケーション |
抗アミロイドモノクローナル抗体を使用した細菌バイオフィルムの根絶
|
|
CA3101553A1
(en)
|
2018-05-31 |
2019-12-05 |
Glaxosmithkline Intellectual Property Development Limited |
Combination of a type ii protein arginine methyltransferase inhibitor and an icos binding protein to treat cancer
|
|
CA3101561A1
(en)
|
2018-05-31 |
2019-12-05 |
Glaxosmithkline Intellectual Property Development Limited |
Combined therapy with icos binding proteins and argininemethyltransferase inhibitors
|
|
WO2020030570A1
(en)
|
2018-08-06 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combinations of an ox40 antibody and a tlr4 modulator and uses thereof
|
|
WO2020030571A1
(en)
|
2018-08-06 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combinations of a pd-1 antibody and a tlr4 modulator and uses thereof
|
|
WO2020031087A1
(en)
|
2018-08-06 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
CN113038967B
(zh)
|
2018-09-06 |
2026-07-14 |
宾夕法尼亚大学理事会 |
人源化抗c5抗体及其用途
|
|
BR112021007517A2
(pt)
|
2018-10-22 |
2021-10-26 |
Glaxosmithkline Intellectual Property Development Limited |
Dosagem
|
|
CN113795512A
(zh)
|
2019-02-01 |
2021-12-14 |
葛兰素史克知识产权开发有限公司 |
包含贝兰他单抗莫福汀和抗ox4抗体的癌症组合治疗及其用途和方法
|
|
CA3143211A1
(en)
|
2019-06-26 |
2020-12-30 |
Glaxosmithkline Intellectual Property Development Limited |
Il1rap binding proteins
|
|
WO2021018941A1
(en)
|
2019-07-31 |
2021-02-04 |
Glaxosmithkline Intellectual Property Development Limited |
Methods of treating cancer
|
|
WO2021043961A1
(en)
|
2019-09-06 |
2021-03-11 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing regimen for the treatment of cancer with an anti icos agonistic antibody and chemotherapy
|
|
WO2021046293A1
(en)
|
2019-09-06 |
2021-03-11 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing regimen for the treatment of cancer with an anti icos agonistic antibody and tremelimumab
|
|
EP4096718A1
(de)
|
2020-01-28 |
2022-12-07 |
GlaxoSmithKline Intellectual Property Development Limited |
Kombinationsbehandlungen und verwendungen und verfahren dafür
|
|
GB202004371D0
(en)
|
2020-03-26 |
2020-05-13 |
Glaxosmithkline Ip Dev Ltd |
CAR constructs
|
|
WO2021209356A1
(en)
|
2020-04-14 |
2021-10-21 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
|
JP2023521228A
(ja)
|
2020-04-14 |
2023-05-23 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
癌の併用療法
|
|
AU2021256925A1
(en)
|
2020-04-14 |
2022-11-03 |
Ares Trading S.A. |
Combination treatment for cancer based upon an ICOS antibody and a PD-L1 antibody TGF-beta-receptor fusion protein
|
|
EP4255928A1
(de)
|
2020-12-02 |
2023-10-11 |
GlaxoSmithKline Intellectual Property Development Limited |
Il-7 bindende proteine und ihre verwendung in der medizinischen therapie
|
|
CN117377691A
(zh)
|
2021-03-19 |
2024-01-09 |
葛兰素史密斯克莱知识产权发展有限公司 |
靶向密蛋白3的嵌合抗原受体和治疗癌症的方法
|
|
WO2023041985A2
(en)
|
2021-09-15 |
2023-03-23 |
New York University In Abu Dhabicorporation |
Compositions that block activation of the sars-cov-2 replication and transcription complex (rtc) and methods of use thereof
|
|
WO2023227641A1
(en)
|
2022-05-27 |
2023-11-30 |
Glaxosmithkline Intellectual Property Development Limited |
Use of tnf-alpha binding proteins and il-7 binding proteins in medical treatment
|
|
WO2024097441A1
(en)
|
2022-11-02 |
2024-05-10 |
Kira Pharmaceuticals (Us) Llc |
Anti-c5 antibody fused to factor h for use in the treatment of complement-mediated diseases
|
|
US20260176337A1
(en)
|
2022-11-02 |
2026-06-25 |
Kira Pharmaceuticals (Us) Llc |
Anti-c5 antibody fused to factor h for use in the treatment of complement-mediated diseases
|
|
WO2024240162A1
(en)
|
2023-05-23 |
2024-11-28 |
Shanghai Allygen Biologics Co., Ltd. |
Pd-l1 and trop-2 targeting conjugates comprising effector molecules and uses thereof
|
|
CN122003435A
(zh)
|
2023-09-03 |
2026-05-08 |
科越医药(美国)有限责任公司 |
包含抗因子d部分的多特异性构建体
|
|
EP4774301A2
(de)
|
2023-09-08 |
2026-07-15 |
Mlab Biosciences, Inc. |
Bifunktionelle proteine und verwendungen davon
|
|
WO2025231454A1
(en)
|
2024-05-02 |
2025-11-06 |
Kira Pharmaceuticals (Us) Llc |
Anti-c5 antibody fused to factor h for use in the treatment of complement-mediated diseases
|
|
WO2026086936A1
(en)
|
2024-10-24 |
2026-04-30 |
Itabmed Co., Ltd. |
Uses of multispecific antigen binding proteins capable of binding cd19 and cd3
|