IL55170A - Indole derivatives,their production and pharmaceutical compositions containing them - Google Patents

Indole derivatives,their production and pharmaceutical compositions containing them

Info

Publication number
IL55170A
IL55170A IL55170A IL5517078A IL55170A IL 55170 A IL55170 A IL 55170A IL 55170 A IL55170 A IL 55170A IL 5517078 A IL5517078 A IL 5517078A IL 55170 A IL55170 A IL 55170A
Authority
IL
Israel
Prior art keywords
production
pharmaceutical compositions
compositions containing
indole derivatives
indole
Prior art date
Application number
IL55170A
Other languages
English (en)
Other versions
IL55170A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH907777A external-priority patent/CH632246A5/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL55170A0 publication Critical patent/IL55170A0/xx
Publication of IL55170A publication Critical patent/IL55170A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL55170A 1977-07-21 1978-07-19 Indole derivatives,their production and pharmaceutical compositions containing them IL55170A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH907377 1977-07-21
CH907777A CH632246A5 (en) 1977-07-21 1977-07-21 Process for preparing novel 3-aminopropoxyindoles
CH907077 1977-07-21
CH906577 1977-07-21

Publications (2)

Publication Number Publication Date
IL55170A0 IL55170A0 (en) 1978-09-29
IL55170A true IL55170A (en) 1982-07-30

Family

ID=27429188

Family Applications (1)

Application Number Title Priority Date Filing Date
IL55170A IL55170A (en) 1977-07-21 1978-07-19 Indole derivatives,their production and pharmaceutical compositions containing them

Country Status (18)

Country Link
JP (1) JPS5422364A (fr)
AU (1) AU523105B2 (fr)
BE (1) BE869133A (fr)
CA (1) CA1098909A (fr)
DE (1) DE2830211A1 (fr)
DK (1) DK312878A (fr)
ES (1) ES471863A1 (fr)
FI (1) FI782229A (fr)
FR (1) FR2398058A1 (fr)
GB (1) GB2001971B (fr)
IE (1) IE47131B1 (fr)
IL (1) IL55170A (fr)
IT (1) IT1105092B (fr)
NL (1) NL7807626A (fr)
NZ (1) NZ187909A (fr)
PT (1) PT68317A (fr)
SE (1) SE435374B (fr)
SU (1) SU843740A3 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905877A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3068678D1 (en) * 1979-08-10 1984-08-30 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE3029980A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Indolderivate und verfahren zu ihrer herstellung
DE3030047A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3131146A1 (de) * 1981-08-06 1983-02-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
EA002984B1 (ru) * 1996-04-09 2002-12-26 Эн Пи Эс Фармасьютикалз, Инк. Кальцилитические соединения, фармацевтические композиции и способ скрининга кальцилитических соединений
ATE215369T1 (de) * 1996-09-05 2002-04-15 Lilly Co Eli Carbazolanaloge als selektive beta3-adrenergische agonisten
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
AU1580001A (en) * 1999-11-15 2001-05-30 Eli Lilly And Company Process for the preparation of aryloxy propanolamines
KR20190017795A (ko) * 2016-05-13 2019-02-20 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 아드레날린 수용체 조절 화합물 및 이의 사용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1547056A (fr) * 1966-12-13 1968-11-22 Sandoz Sa Dérivés de l'indole et leur préparation
FR2019185A1 (en) * 1968-09-30 1970-06-26 Sandoz Sa 4-(2-hydroxy-3-amino-propoxy)-indole-2-carboxy- - lic acids and esters and 2-hydroxymethylindoles as beta
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
US4076829A (en) * 1974-11-16 1978-02-28 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2508251C2 (de) * 1975-02-26 1983-12-29 Boehringer Mannheim Gmbh, 6800 Mannheim Derivate des Indols, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
DE2633839A1 (de) * 1975-08-07 1977-02-24 Sandoz Ag Neue 4-aminopropoxyindolderivate, ihre herstellung und verwendung
DE2635209C2 (de) * 1975-08-15 1983-01-27 Sandoz-Patent-GmbH, 7850 Lörrach 4-(2-Benzoyloxy-3-tert.butylamino-propoxy)-2-methylindol, dessen (S)-Enantiomeres, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Heilmittel

Also Published As

Publication number Publication date
FR2398058A1 (fr) 1979-02-16
BE869133A (fr) 1979-01-19
IE47131B1 (en) 1983-12-28
SE435374B (sv) 1984-09-24
IL55170A0 (en) 1978-09-29
IT1105092B (it) 1985-10-28
DK312878A (da) 1979-01-22
FI782229A (fi) 1979-01-22
PT68317A (fr) 1978-08-01
NZ187909A (en) 1981-04-24
GB2001971B (en) 1982-02-10
SU843740A3 (ru) 1981-06-30
GB2001971A (en) 1979-02-14
IE781448L (en) 1979-01-21
SE7807753L (sv) 1979-01-22
JPS5422364A (en) 1979-02-20
DE2830211A1 (de) 1979-02-01
IT7850299A0 (it) 1978-07-14
CA1098909A (fr) 1981-04-07
AU3818278A (en) 1980-01-24
ES471863A1 (es) 1979-10-01
NL7807626A (nl) 1979-01-23
FR2398058B1 (fr) 1982-08-06
AU523105B2 (en) 1982-07-15

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