IT1105092B - Derivati dell'indolo loro preparazione e loro applicazione quali medicamenti - Google Patents
Derivati dell'indolo loro preparazione e loro applicazione quali medicamentiInfo
- Publication number
- IT1105092B IT1105092B IT50299/78A IT5029978A IT1105092B IT 1105092 B IT1105092 B IT 1105092B IT 50299/78 A IT50299/78 A IT 50299/78A IT 5029978 A IT5029978 A IT 5029978A IT 1105092 B IT1105092 B IT 1105092B
- Authority
- IT
- Italy
- Prior art keywords
- indolation
- medications
- derivatives
- preparation
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH907377 | 1977-07-21 | ||
| CH907777A CH632246A5 (en) | 1977-07-21 | 1977-07-21 | Process for preparing novel 3-aminopropoxyindoles |
| CH907077 | 1977-07-21 | ||
| CH906577 | 1977-07-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7850299A0 IT7850299A0 (it) | 1978-07-14 |
| IT1105092B true IT1105092B (it) | 1985-10-28 |
Family
ID=27429188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT50299/78A IT1105092B (it) | 1977-07-21 | 1978-07-14 | Derivati dell'indolo loro preparazione e loro applicazione quali medicamenti |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5422364A (it) |
| AU (1) | AU523105B2 (it) |
| BE (1) | BE869133A (it) |
| CA (1) | CA1098909A (it) |
| DE (1) | DE2830211A1 (it) |
| DK (1) | DK312878A (it) |
| ES (1) | ES471863A1 (it) |
| FI (1) | FI782229A (it) |
| FR (1) | FR2398058A1 (it) |
| GB (1) | GB2001971B (it) |
| IE (1) | IE47131B1 (it) |
| IL (1) | IL55170A (it) |
| IT (1) | IT1105092B (it) |
| NL (1) | NL7807626A (it) |
| NZ (1) | NZ187909A (it) |
| PT (1) | PT68317A (it) |
| SE (1) | SE435374B (it) |
| SU (1) | SU843740A3 (it) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2905877A1 (de) * | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3068678D1 (en) * | 1979-08-10 | 1984-08-30 | Sandoz Ag | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
| DE3029980A1 (de) * | 1980-08-08 | 1982-03-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Indolderivate und verfahren zu ihrer herstellung |
| DE3030047A1 (de) * | 1980-08-08 | 1982-03-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3131146A1 (de) * | 1981-08-06 | 1983-02-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
| EA002984B1 (ru) * | 1996-04-09 | 2002-12-26 | Эн Пи Эс Фармасьютикалз, Инк. | Кальцилитические соединения, фармацевтические композиции и способ скрининга кальцилитических соединений |
| ATE215369T1 (de) * | 1996-09-05 | 2002-04-15 | Lilly Co Eli | Carbazolanaloge als selektive beta3-adrenergische agonisten |
| US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
| TW483881B (en) | 1996-12-03 | 2002-04-21 | Nps Pharma Inc | Calcilytic compounds |
| AU1580001A (en) * | 1999-11-15 | 2001-05-30 | Eli Lilly And Company | Process for the preparation of aryloxy propanolamines |
| KR20190017795A (ko) * | 2016-05-13 | 2019-02-20 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 | 아드레날린 수용체 조절 화합물 및 이의 사용 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1547056A (fr) * | 1966-12-13 | 1968-11-22 | Sandoz Sa | Dérivés de l'indole et leur préparation |
| FR2019185A1 (en) * | 1968-09-30 | 1970-06-26 | Sandoz Sa | 4-(2-hydroxy-3-amino-propoxy)-indole-2-carboxy- - lic acids and esters and 2-hydroxymethylindoles as beta |
| US3699123A (en) * | 1970-03-24 | 1972-10-17 | Sandoz Ltd | 4-(3-amino-2-hydroxy-propoxy) indole derivatives |
| US4076829A (en) * | 1974-11-16 | 1978-02-28 | Boehringer Mannheim Gmbh | Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases |
| DE2508251C2 (de) * | 1975-02-26 | 1983-12-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Derivate des Indols, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel |
| DE2633839A1 (de) * | 1975-08-07 | 1977-02-24 | Sandoz Ag | Neue 4-aminopropoxyindolderivate, ihre herstellung und verwendung |
| DE2635209C2 (de) * | 1975-08-15 | 1983-01-27 | Sandoz-Patent-GmbH, 7850 Lörrach | 4-(2-Benzoyloxy-3-tert.butylamino-propoxy)-2-methylindol, dessen (S)-Enantiomeres, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Heilmittel |
-
1978
- 1978-07-10 DE DE19782830211 patent/DE2830211A1/de not_active Ceased
- 1978-07-12 DK DK312878A patent/DK312878A/da not_active Application Discontinuation
- 1978-07-12 FI FI782229A patent/FI782229A/fi not_active Application Discontinuation
- 1978-07-12 SE SE7807753A patent/SE435374B/sv unknown
- 1978-07-14 IT IT50299/78A patent/IT1105092B/it active
- 1978-07-17 NL NL7807626A patent/NL7807626A/xx not_active Application Discontinuation
- 1978-07-19 GB GB7830345A patent/GB2001971B/en not_active Expired
- 1978-07-19 SU SU782639449A patent/SU843740A3/ru active
- 1978-07-19 BE BE189392A patent/BE869133A/xx not_active IP Right Cessation
- 1978-07-19 IE IE1448/78A patent/IE47131B1/en unknown
- 1978-07-19 PT PT68317A patent/PT68317A/pt unknown
- 1978-07-19 ES ES471863A patent/ES471863A1/es not_active Expired
- 1978-07-19 AU AU38182/78A patent/AU523105B2/en not_active Expired
- 1978-07-19 NZ NZ187909A patent/NZ187909A/xx unknown
- 1978-07-19 IL IL55170A patent/IL55170A/xx unknown
- 1978-07-20 JP JP8781878A patent/JPS5422364A/ja active Pending
- 1978-07-20 CA CA307,768A patent/CA1098909A/en not_active Expired
- 1978-07-21 FR FR7821679A patent/FR2398058A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2398058A1 (fr) | 1979-02-16 |
| BE869133A (fr) | 1979-01-19 |
| IE47131B1 (en) | 1983-12-28 |
| SE435374B (sv) | 1984-09-24 |
| IL55170A0 (en) | 1978-09-29 |
| DK312878A (da) | 1979-01-22 |
| FI782229A (fi) | 1979-01-22 |
| PT68317A (fr) | 1978-08-01 |
| NZ187909A (en) | 1981-04-24 |
| GB2001971B (en) | 1982-02-10 |
| SU843740A3 (ru) | 1981-06-30 |
| GB2001971A (en) | 1979-02-14 |
| IE781448L (en) | 1979-01-21 |
| SE7807753L (sv) | 1979-01-22 |
| JPS5422364A (en) | 1979-02-20 |
| IL55170A (en) | 1982-07-30 |
| DE2830211A1 (de) | 1979-02-01 |
| IT7850299A0 (it) | 1978-07-14 |
| CA1098909A (en) | 1981-04-07 |
| AU3818278A (en) | 1980-01-24 |
| ES471863A1 (es) | 1979-10-01 |
| NL7807626A (nl) | 1979-01-23 |
| FR2398058B1 (it) | 1982-08-06 |
| AU523105B2 (en) | 1982-07-15 |
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