NZ187909A - 3-(indol-4-yloxy)-1-substitutedaminopropan-2-ols and pharmaceutical compositions - Google Patents

3-(indol-4-yloxy)-1-substitutedaminopropan-2-ols and pharmaceutical compositions

Info

Publication number
NZ187909A
NZ187909A NZ187909A NZ18790978A NZ187909A NZ 187909 A NZ187909 A NZ 187909A NZ 187909 A NZ187909 A NZ 187909A NZ 18790978 A NZ18790978 A NZ 18790978A NZ 187909 A NZ187909 A NZ 187909A
Authority
NZ
New Zealand
Prior art keywords
substitutedaminopropan
ols
indol
yloxy
pharmaceutical compositions
Prior art date
Application number
NZ187909A
Inventor
R Berthold
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH907777A external-priority patent/CH632246A5/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of NZ187909A publication Critical patent/NZ187909A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
NZ187909A 1977-07-21 1978-07-19 3-(indol-4-yloxy)-1-substitutedaminopropan-2-ols and pharmaceutical compositions NZ187909A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH907377 1977-07-21
CH906577 1977-07-21
CH907777A CH632246A5 (en) 1977-07-21 1977-07-21 Process for preparing novel 3-aminopropoxyindoles
CH907077 1977-07-21

Publications (1)

Publication Number Publication Date
NZ187909A true NZ187909A (en) 1981-04-24

Family

ID=27429188

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ187909A NZ187909A (en) 1977-07-21 1978-07-19 3-(indol-4-yloxy)-1-substitutedaminopropan-2-ols and pharmaceutical compositions

Country Status (18)

Country Link
JP (1) JPS5422364A (en)
AU (1) AU523105B2 (en)
BE (1) BE869133A (en)
CA (1) CA1098909A (en)
DE (1) DE2830211A1 (en)
DK (1) DK312878A (en)
ES (1) ES471863A1 (en)
FI (1) FI782229A (en)
FR (1) FR2398058A1 (en)
GB (1) GB2001971B (en)
IE (1) IE47131B1 (en)
IL (1) IL55170A (en)
IT (1) IT1105092B (en)
NL (1) NL7807626A (en)
NZ (1) NZ187909A (en)
PT (1) PT68317A (en)
SE (1) SE435374B (en)
SU (1) SU843740A3 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905877A1 (en) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
EP0025111B1 (en) * 1979-08-10 1984-07-25 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE3029980A1 (en) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim INDOLDER DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3030047A1 (en) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3131146A1 (en) * 1981-08-06 1983-02-24 Boehringer Mannheim Gmbh, 6800 Mannheim NEW HETEROARYLOXYPROPANOLAMINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
AU726659B2 (en) 1996-04-09 2000-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
ATE215369T1 (en) * 1996-09-05 2002-04-15 Lilly Co Eli CARBAZOLE ANALOGUES AS SELECTIVE BETA3-ADRENERGIC AGONISTS
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
WO2001036412A1 (en) * 1999-11-15 2001-05-25 Eli Lilly And Company Process for the preparation of aryloxy propanolamines
KR20190017795A (en) 2016-05-13 2019-02-20 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 Adrenergic receptor modulating compounds and methods for their use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1547056A (en) * 1966-12-13 1968-11-22 Sandoz Sa Indole derivatives and their preparation
FR2019185A1 (en) * 1968-09-30 1970-06-26 Sandoz Sa 4-(2-hydroxy-3-amino-propoxy)-indole-2-carboxy- - lic acids and esters and 2-hydroxymethylindoles as beta
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
US4076829A (en) * 1974-11-16 1978-02-28 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2508251C2 (en) * 1975-02-26 1983-12-29 Boehringer Mannheim Gmbh, 6800 Mannheim Derivatives of indole, processes for their preparation and medicaments containing them
DE2633839A1 (en) * 1975-08-07 1977-02-24 Sandoz Ag NEW 4-AMINOPROPOXYINDOLDE DERIVATIVES, THEIR PRODUCTION AND USE
DE2635209C2 (en) * 1975-08-15 1983-01-27 Sandoz-Patent-GmbH, 7850 Lörrach 4- (2-Benzoyloxy-3-tert-butylamino-propoxy) -2-methylindole, its (S) -enantiomer, their acid addition salts, processes for their preparation and medicaments containing these compounds

Also Published As

Publication number Publication date
FR2398058A1 (en) 1979-02-16
IE781448L (en) 1979-01-21
IL55170A0 (en) 1978-09-29
GB2001971A (en) 1979-02-14
AU523105B2 (en) 1982-07-15
CA1098909A (en) 1981-04-07
IL55170A (en) 1982-07-30
NL7807626A (en) 1979-01-23
SE435374B (en) 1984-09-24
DK312878A (en) 1979-01-22
ES471863A1 (en) 1979-10-01
SE7807753L (en) 1979-01-22
DE2830211A1 (en) 1979-02-01
IT1105092B (en) 1985-10-28
GB2001971B (en) 1982-02-10
BE869133A (en) 1979-01-19
AU3818278A (en) 1980-01-24
IT7850299A0 (en) 1978-07-14
FI782229A (en) 1979-01-22
IE47131B1 (en) 1983-12-28
PT68317A (en) 1978-08-01
FR2398058B1 (en) 1982-08-06
JPS5422364A (en) 1979-02-20
SU843740A3 (en) 1981-06-30

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