IT1189208B - Derivati dell'indolo,loro preparazione e loro impiego come medicamenti - Google Patents

Derivati dell'indolo,loro preparazione e loro impiego come medicamenti

Info

Publication number
IT1189208B
IT1189208B IT8247582A IT4758282A IT1189208B IT 1189208 B IT1189208 B IT 1189208B IT 8247582 A IT8247582 A IT 8247582A IT 4758282 A IT4758282 A IT 4758282A IT 1189208 B IT1189208 B IT 1189208B
Authority
IT
Italy
Prior art keywords
medications
preparation
indole derivatives
indole
derivatives
Prior art date
Application number
IT8247582A
Other languages
English (en)
Inventor
Richard Berthold
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of IT1189208B publication Critical patent/IT1189208B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8247582A 1981-01-16 1982-01-15 Derivati dell'indolo,loro preparazione e loro impiego come medicamenti IT1189208B (it)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH27581 1981-01-16
CH47581 1981-01-26
CH84981 1981-02-09
CH85281 1981-02-09
CH84681 1981-02-09

Publications (1)

Publication Number Publication Date
IT1189208B true IT1189208B (it) 1988-01-28

Family

ID=27508797

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8247582A IT1189208B (it) 1981-01-16 1982-01-15 Derivati dell'indolo,loro preparazione e loro impiego come medicamenti

Country Status (10)

Country Link
US (1) US4460586A (it)
AU (1) AU7952682A (it)
DE (1) DE3200304A1 (it)
FR (1) FR2498188B1 (it)
GB (1) GB2091262B (it)
IL (1) IL64777A0 (it)
IT (1) IT1189208B (it)
NZ (1) NZ199489A (it)
SE (1) SE8200171L (it)
WO (1) WO1982002550A1 (it)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3310891A1 (de) * 1983-03-25 1984-09-27 Boehringer Mannheim Gmbh, 6800 Mannheim Neue indolinon-(2)-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
DE3423429A1 (de) * 1984-06-26 1986-01-02 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkylaminopropanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
GB2163150B (en) * 1984-07-19 1988-05-25 Sandoz Ltd 3-aminopropoxyaryl derivatives
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
DE3721260A1 (de) * 1987-06-27 1989-01-12 Beiersdorf Ag Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US4980351A (en) * 1987-11-04 1990-12-25 Warner-Lambert Company 3-aminopropoxyaryl derivatives having cardiotonic and antihypertensive use and compositions thereof
US4876257A (en) * 1988-03-03 1989-10-24 Ortho Pharmaceutical Corporation 6-Substituted purinyl piperazine derivatives useful as cardiotonic and antiarrhythmic agents
US4885300A (en) * 1988-03-03 1989-12-05 Ortho Pharmaceutical Corporation 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives
DE4002391A1 (de) * 1990-01-27 1991-08-01 Beiersdorf Ag Indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5215987A (en) * 1990-04-23 1993-06-01 Ortho Pharmaceutical Corporation Substituted benzhydryl 2-hydroxypropyl piperazine derivatives
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
TW205034B (it) * 1990-09-13 1993-05-01 Pola Kasei Kogyo Kk
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1129072A (en) * 1966-02-01 1968-10-02 Ici Ltd Benzofuran and indole derivatives
CH475981A (de) * 1966-12-13 1969-07-31 Sandoz Ag Verfahren zur Herstellung neuer Indol-Derivate
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
GB1410783A (en) * 1972-01-20 1975-10-22 Wyeth John & Brother Ltd N-substituted 4-amidopyridines tetrahydropyridines and piperidines
BE794333A (fr) * 1972-01-20 1973-07-19 Wyeth John & Brother Ltd Composes heterocycliques azotes therapeutiques
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
US4061641A (en) * 1973-10-10 1977-12-06 John Wyeth & Brother Limited Ureidopiperidino-ketoalkyl indoles
GB1543619A (en) * 1976-03-12 1979-04-04 Wyeth John & Brother Ltd Process for preparing 3-(heterocycloalkyl)-indole derivatives
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
FI782133A (fi) * 1977-07-08 1979-01-09 Ciba Geigy Ag Piperidino-propanoler och foerfarande foer deras framstaellning
DE2960178D1 (en) * 1978-06-06 1981-04-09 Hoechst Ag New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
DE2905876A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3068678D1 (en) * 1979-08-10 1984-08-30 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
CH647235A5 (de) * 1980-02-13 1985-01-15 Sandoz Ag 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung.
JPS56142262A (en) * 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative

Also Published As

Publication number Publication date
US4460586A (en) 1984-07-17
IL64777A0 (en) 1982-03-31
FR2498188A1 (fr) 1982-07-23
NZ199489A (en) 1985-11-08
GB2091262B (en) 1985-02-13
AU7952682A (en) 1982-07-22
WO1982002550A1 (en) 1982-08-05
SE8200171L (sv) 1982-07-17
GB2091262A (en) 1982-07-28
FR2498188B1 (fr) 1983-09-02
DE3200304A1 (de) 1982-08-26

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