DK312878A - Fremgangsmaade til fremstilling af indolderivater - Google Patents

Fremgangsmaade til fremstilling af indolderivater

Info

Publication number
DK312878A
DK312878A DK312878A DK312878A DK312878A DK 312878 A DK312878 A DK 312878A DK 312878 A DK312878 A DK 312878A DK 312878 A DK312878 A DK 312878A DK 312878 A DK312878 A DK 312878A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
derivatives
content
content derivatives
Prior art date
Application number
DK312878A
Other languages
Danish (da)
English (en)
Inventor
R Berthold
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH907777A external-priority patent/CH632246A5/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK312878A publication Critical patent/DK312878A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK312878A 1977-07-21 1978-07-12 Fremgangsmaade til fremstilling af indolderivater DK312878A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH907077 1977-07-21
CH907377 1977-07-21
CH907777A CH632246A5 (en) 1977-07-21 1977-07-21 Process for preparing novel 3-aminopropoxyindoles
CH906577 1977-07-21

Publications (1)

Publication Number Publication Date
DK312878A true DK312878A (da) 1979-01-22

Family

ID=27429188

Family Applications (1)

Application Number Title Priority Date Filing Date
DK312878A DK312878A (da) 1977-07-21 1978-07-12 Fremgangsmaade til fremstilling af indolderivater

Country Status (18)

Country Link
JP (1) JPS5422364A (fr)
AU (1) AU523105B2 (fr)
BE (1) BE869133A (fr)
CA (1) CA1098909A (fr)
DE (1) DE2830211A1 (fr)
DK (1) DK312878A (fr)
ES (1) ES471863A1 (fr)
FI (1) FI782229A (fr)
FR (1) FR2398058A1 (fr)
GB (1) GB2001971B (fr)
IE (1) IE47131B1 (fr)
IL (1) IL55170A (fr)
IT (1) IT1105092B (fr)
NL (1) NL7807626A (fr)
NZ (1) NZ187909A (fr)
PT (1) PT68317A (fr)
SE (1) SE435374B (fr)
SU (1) SU843740A3 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK156392B (da) * 1979-08-10 1989-08-14 Sandoz Ag Analogifremgangsmaade til fremstilling af aminopropoxyindolderivater

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905877A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3030047A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3029980A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Indolderivate und verfahren zu ihrer herstellung
DE3131146A1 (de) * 1981-08-06 1983-02-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
SG99290A1 (en) * 1996-04-09 2003-10-27 Nps Pharma Inc Calcilytic compounds
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
ES2171839T3 (es) * 1996-09-05 2002-09-16 Lilly Co Eli Analogos de carbazol como agonistas adrenergicos selectivos de beta3.
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
AU1580001A (en) * 1999-11-15 2001-05-30 Eli Lilly And Company Process for the preparation of aryloxy propanolamines
BR112018073227A2 (pt) 2016-05-13 2019-02-19 The Board Of Trustees Of The Leland Stanford Junior University compostos moduladores do receptor adrenérgico e métodos de uso do mesmo

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1547056A (fr) * 1966-12-13 1968-11-22 Sandoz Sa Dérivés de l'indole et leur préparation
FR2019185A1 (en) * 1968-09-30 1970-06-26 Sandoz Sa 4-(2-hydroxy-3-amino-propoxy)-indole-2-carboxy- - lic acids and esters and 2-hydroxymethylindoles as beta
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
DE2508251C2 (de) * 1975-02-26 1983-12-29 Boehringer Mannheim Gmbh, 6800 Mannheim Derivate des Indols, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
US4076829A (en) * 1974-11-16 1978-02-28 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2633839A1 (de) * 1975-08-07 1977-02-24 Sandoz Ag Neue 4-aminopropoxyindolderivate, ihre herstellung und verwendung
DE2635209C2 (de) * 1975-08-15 1983-01-27 Sandoz-Patent-GmbH, 7850 Lörrach 4-(2-Benzoyloxy-3-tert.butylamino-propoxy)-2-methylindol, dessen (S)-Enantiomeres, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Heilmittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK156392B (da) * 1979-08-10 1989-08-14 Sandoz Ag Analogifremgangsmaade til fremstilling af aminopropoxyindolderivater

Also Published As

Publication number Publication date
FR2398058A1 (fr) 1979-02-16
SE7807753L (sv) 1979-01-22
PT68317A (fr) 1978-08-01
CA1098909A (fr) 1981-04-07
BE869133A (fr) 1979-01-19
ES471863A1 (es) 1979-10-01
AU523105B2 (en) 1982-07-15
IT7850299A0 (it) 1978-07-14
GB2001971B (en) 1982-02-10
IE781448L (en) 1979-01-21
NZ187909A (en) 1981-04-24
IL55170A (en) 1982-07-30
NL7807626A (nl) 1979-01-23
FR2398058B1 (fr) 1982-08-06
JPS5422364A (en) 1979-02-20
IT1105092B (it) 1985-10-28
IE47131B1 (en) 1983-12-28
IL55170A0 (en) 1978-09-29
DE2830211A1 (de) 1979-02-01
AU3818278A (en) 1980-01-24
SU843740A3 (ru) 1981-06-30
GB2001971A (en) 1979-02-14
FI782229A (fi) 1979-01-22
SE435374B (sv) 1984-09-24

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