IL47411A - 1-(2-( -naphthyloxy)-ethyl)-3-methyl-pyrazolone-(5),process for its preparation and antithrombotic compositions containing it - Google Patents
1-(2-( -naphthyloxy)-ethyl)-3-methyl-pyrazolone-(5),process for its preparation and antithrombotic compositions containing itInfo
- Publication number
- IL47411A IL47411A IL7547411A IL4741175A IL47411A IL 47411 A IL47411 A IL 47411A IL 7547411 A IL7547411 A IL 7547411A IL 4741175 A IL4741175 A IL 4741175A IL 47411 A IL47411 A IL 47411A
- Authority
- IL
- Israel
- Prior art keywords
- naphthyloxy
- pyrazolone
- ethyl
- methyl
- preparation
- Prior art date
Links
- 230000002785 anti-thrombosis Effects 0.000 title abstract 2
- 239000003146 anticoagulant agent Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 2-beta-naphthoxyethyl halide Chemical class 0.000 abstract 1
- BORMNCXGATVZMD-UHFFFAOYSA-N 2-naphthalen-2-yloxyethylhydrazine Chemical compound C1=CC=CC2=CC(OCCNN)=CC=C21 BORMNCXGATVZMD-UHFFFAOYSA-N 0.000 abstract 1
- WGVHNCAJPFIFCR-UHFFFAOYSA-N 5-methyl-1,2-dihydropyrazol-3-one Chemical compound CC1=CC(O)=NN1 WGVHNCAJPFIFCR-UHFFFAOYSA-N 0.000 abstract 1
- INCLABAHEPQBCG-UHFFFAOYSA-N 5-methyl-2-(2-naphthalen-2-yloxyethyl)-1h-pyrazol-3-one Chemical compound N1C(C)=CC(=O)N1CCOC1=CC=C(C=CC=C2)C2=C1 INCLABAHEPQBCG-UHFFFAOYSA-N 0.000 abstract 1
- WOFAGNLBCJWEOE-UHFFFAOYSA-N Benzyl acetoacetate Chemical compound CC(=O)CC(=O)OCC1=CC=CC=C1 WOFAGNLBCJWEOE-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000003385 sodium Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000002537 thrombolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2427272A DE2427272C3 (de) | 1974-06-06 | 1974-06-06 | 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL47411A0 IL47411A0 (en) | 1975-08-31 |
| IL47411A true IL47411A (en) | 1979-07-25 |
Family
ID=5917444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL7547411A IL47411A (en) | 1974-06-06 | 1975-06-03 | 1-(2-( -naphthyloxy)-ethyl)-3-methyl-pyrazolone-(5),process for its preparation and antithrombotic compositions containing it |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US4053621A (is") |
| JP (1) | JPS5840544B2 (is") |
| AR (3) | AR207176A1 (is") |
| AT (1) | AT342584B (is") |
| BE (1) | BE829850A (is") |
| BG (3) | BG23005A3 (is") |
| CA (1) | CA1051001A (is") |
| CH (3) | CH612673A5 (is") |
| CS (1) | CS193513B2 (is") |
| DD (1) | DD123886A5 (is") |
| DE (1) | DE2427272C3 (is") |
| DK (1) | DK134753C (is") |
| EG (1) | EG11950A (is") |
| ES (2) | ES454281A1 (is") |
| FI (1) | FI57586C (is") |
| FR (1) | FR2273535A1 (is") |
| GB (1) | GB1454733A (is") |
| HK (1) | HK26877A (is") |
| HU (1) | HU169651B (is") |
| IE (1) | IE41256B1 (is") |
| IL (1) | IL47411A (is") |
| KE (1) | KE2991A (is") |
| LU (1) | LU72645A1 (is") |
| NL (1) | NL181803C (is") |
| NO (1) | NO141757C (is") |
| PH (2) | PH12446A (is") |
| PL (3) | PL96609B1 (is") |
| RO (3) | RO73053A (is") |
| SE (1) | SE414766B (is") |
| SU (3) | SU544373A3 (is") |
| YU (3) | YU141575A (is") |
| ZA (1) | ZA753644B (is") |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8201321A (nl) * | 1981-04-07 | 1982-11-01 | Bayer Ag | Werkwijze voor de behandeling van metastase en de groei van tumorcellen. |
| US4539206A (en) * | 1981-05-06 | 1985-09-03 | Alcusal Incorporated Pty. Ltd. | Topical compositions containing copper (II) complexes of 3,5-dioxo-pyrazolidine derivatives and methods of combatting inflammation with them |
| US4540707A (en) * | 1983-01-28 | 1985-09-10 | Bayer Aktiengesellschaft | Nafazatrom as a lipoxygenase inhibitor |
| DK143684A (da) * | 1983-03-12 | 1984-09-13 | Bayer Ag | Anvendelse af pyrazolonderivater som lipoxygenasehaemmer ved terapi af isaer ischaemi og hjerterytmeforstyrrelser |
| USRE35801E (en) * | 1985-05-20 | 1998-05-19 | Mitsubishi Chemical Corporation | Prophylactic and therapeutic composition for circulatory disorders and method of treatment |
| DK169672B1 (da) * | 1985-05-20 | 1995-01-09 | Mitsubishi Chem Ind | Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3147276A (en) * | 1964-09-01 | Pyrazolones | ||
| US2476987A (en) * | 1949-07-26 | S-acyloxy pyrazqles and method foe | ||
| US2376380A (en) * | 1945-05-22 | Preparation of amino pyrazolones | ||
| US2476986A (en) * | 1949-07-26 | Elmobe louis martin | ||
| GB599919A (en) | 1944-12-11 | 1948-03-24 | Kodak Ltd | Improvements in the manufacture of aminopyrazolones and their use as colour couplers |
| GB636988A (en) * | 1947-12-24 | 1950-05-10 | Gevaert Photo Producten Naamlo | Improvements in and relating to the production of colour photographic images |
| US2511231A (en) * | 1949-03-26 | 1950-06-13 | Eastman Kodak Co | 1-cyanophenyl-3-acylamino-5-pyrazolone couplers for color photography |
| US2600788A (en) * | 1949-06-07 | 1952-06-17 | Eastman Kodak Co | Halogen-substituted pyrazolone couplers for color photography |
| CA519436A (en) * | 1949-08-22 | 1955-12-13 | Gysin Hans | Carbamic acid esters as well as pest combatting agents and a method of making the same |
| US2672417A (en) * | 1949-12-31 | 1954-03-16 | Gevaert Photo Prod Nv | Production of color photographic images |
| GB779703A (en) | 1953-07-06 | 1957-07-24 | Hoechst Ag | Pyrazolone compounds and a process for making them |
| US2848446A (en) * | 1954-02-23 | 1958-08-19 | Saul & Co | Azo dyestuffs |
| US3014916A (en) * | 1959-01-22 | 1961-12-26 | May & Baker Ltd | Pyrazole derivatives |
| GB935538A (en) * | 1959-04-06 | 1963-08-28 | Stop Motion Devices Corp | Stop-motion head for use on knitting machines |
| GB961037A (en) | 1960-08-23 | 1964-06-17 | Smith & Nephew | Pyrazolones and processes for their preparation |
| NL279140A (is") * | 1961-05-31 | |||
| US3190888A (en) * | 1963-08-22 | 1965-06-22 | American Home Prod | Aryloxyalkylpyrazole |
| DE1670529C3 (de) * | 1966-07-13 | 1974-01-10 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Substituierte s-Triazine |
| GB1190914A (en) | 1966-09-26 | 1970-05-06 | Agfa Gevaert Nv | 2-Pyrazolin-5-Ones and the use thereof as Colour Couplers |
| FR1558513A (is") * | 1968-01-04 | 1969-02-28 | ||
| GB1247688A (en) | 1968-02-26 | 1971-09-29 | Agfa Gevaert | Monomeric and polymeric 2-pyrazoline-5-one colour couplers |
| JPS4818858B1 (is") * | 1969-04-07 | 1973-06-08 | ||
| FR2068413A1 (en) | 1969-10-22 | 1971-08-27 | Synthelabo | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives |
| US3615506A (en) * | 1970-02-09 | 1971-10-26 | Eastman Kodak Co | Silver halide emulsions containing 3-cyclicamino-5-pyrazolone color couplers |
| US3694456A (en) * | 1970-05-08 | 1972-09-26 | Takeda Chemical Industries Ltd | 1-disubstituted aminopyrazoles |
| FR2101060B1 (is") * | 1970-08-14 | 1974-02-01 | Roussel Uclaf | |
| JPS5417772B1 (is") * | 1970-12-04 | 1979-07-03 | ||
| JPS548689B1 (is") * | 1970-12-04 | 1979-04-18 | ||
| DE2319281A1 (de) * | 1973-04-17 | 1974-11-07 | Bayer Ag | Diuretisches und antihypertensives mittel |
| AR207445A1 (es) * | 1973-04-17 | 1976-10-08 | Bayer Ag | Procedimiento de preparacion de nuevos derivados de pirazolonas-(5)-1-substituidas |
| DE2319278C2 (de) | 1973-04-17 | 1986-02-20 | Bayer Ag, 5090 Leverkusen | Pharmazeutisches Mittel |
-
1974
- 1974-06-06 DE DE2427272A patent/DE2427272C3/de not_active Expired
-
1975
- 1975-01-01 AR AR261806A patent/AR207176A1/es active
- 1975-01-01 AR AR261807A patent/AR207177A1/es active
- 1975-01-01 AR AR259115A patent/AR207044A1/es active
- 1975-04-05 RO RO7591324A patent/RO73053A/ro unknown
- 1975-05-06 GB GB1897075A patent/GB1454733A/en not_active Expired
- 1975-05-23 NO NO751846A patent/NO141757C/no unknown
- 1975-05-24 EG EG75308A patent/EG11950A/xx active
- 1975-05-26 BG BG030937A patent/BG23005A3/xx unknown
- 1975-05-26 BG BG030936A patent/BG24410A3/xx unknown
- 1975-05-28 SU SU2138693A patent/SU544373A3/ru active
- 1975-06-02 US US05/582,773 patent/US4053621A/en not_active Expired - Lifetime
- 1975-06-02 BG BG030159A patent/BG23899A3/xx unknown
- 1975-06-02 YU YU01415/75A patent/YU141575A/xx unknown
- 1975-06-03 IL IL7547411A patent/IL47411A/xx unknown
- 1975-06-03 PH PH17223A patent/PH12446A/en unknown
- 1975-06-04 LU LU72645A patent/LU72645A1/xx unknown
- 1975-06-04 CH CH137079A patent/CH612673A5/xx not_active IP Right Cessation
- 1975-06-04 DK DK253475A patent/DK134753C/da not_active IP Right Cessation
- 1975-06-04 CH CH136979A patent/CH612672A5/xx not_active IP Right Cessation
- 1975-06-04 AT AT424875A patent/AT342584B/de not_active IP Right Cessation
- 1975-06-04 PL PL1975193711A patent/PL96609B1/pl unknown
- 1975-06-04 BE BE157016A patent/BE829850A/xx not_active IP Right Cessation
- 1975-06-04 CH CH720675A patent/CH611889A5/xx not_active IP Right Cessation
- 1975-06-04 FI FI751654A patent/FI57586C/fi not_active IP Right Cessation
- 1975-06-04 JP JP50066633A patent/JPS5840544B2/ja not_active Expired
- 1975-06-04 PL PL1975193710A patent/PL96608B1/pl unknown
- 1975-06-04 DD DD186449A patent/DD123886A5/xx unknown
- 1975-06-04 PL PL1975180895A patent/PL93913B1/pl unknown
- 1975-06-05 ZA ZA00753644A patent/ZA753644B/xx unknown
- 1975-06-05 CS CS753956A patent/CS193513B2/cs unknown
- 1975-06-05 IE IE1269/75A patent/IE41256B1/xx unknown
- 1975-06-05 RO RO7582444A patent/RO79056A/ro unknown
- 1975-06-05 RO RO7591325A patent/RO73054A/ro unknown
- 1975-06-05 SE SE7506435A patent/SE414766B/xx not_active IP Right Cessation
- 1975-06-06 CA CA228,726A patent/CA1051001A/en not_active Expired
- 1975-06-06 HU HUBA3276A patent/HU169651B/hu unknown
- 1975-06-06 NL NLAANVRAGE7506765,A patent/NL181803C/xx not_active IP Right Cessation
- 1975-06-06 FR FR7517765A patent/FR2273535A1/fr active Granted
- 1975-12-16 ES ES454281A patent/ES454281A1/es not_active Expired
-
1976
- 1976-03-12 SU SU762331906A patent/SU586839A3/ru active
- 1976-03-12 SU SU762331907A patent/SU588917A3/ru active
- 1976-10-19 PH PH19016A patent/PH14053A/en unknown
- 1976-12-16 ES ES454280A patent/ES454280A1/es not_active Expired
-
1977
- 1977-06-02 HK HK268/77A patent/HK26877A/xx unknown
-
1979
- 1979-09-11 KE KE2991A patent/KE2991A/xx unknown
-
1981
- 1981-07-08 YU YU01691/81A patent/YU169181A/xx unknown
- 1981-07-08 YU YU01692/81A patent/YU169281A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3460577D1 (en) | Sodium salt of ursodeoxycholic sulphate | |
| GB1503581A (en) | Process for the manufacture of 7-beta-amino-cephem-3-ol-4-carboxylic acid compounds | |
| SU586839A3 (ru) | Способ получени 1-/2-( -нафтилекси) -этил/-3-метилпиразолена-5 | |
| GB1409648A (en) | Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof | |
| GB1528713A (en) | N-(mercaptoacyl)-histidine | |
| GB1497729A (en) | Benzenesulphonyl ureas and process for their manufacture | |
| GB1334693A (en) | Acenaphthene derivatives | |
| GB1240817A (en) | Herbicidal agents | |
| GB1501438A (en) | Fused pyrimidine-4-(3h)-ones and preparation thereof | |
| GB1490169A (en) | N-vinyloxyethyl-alpha-methyl-beta-phenethylamines | |
| ES8401752A1 (es) | Procedimiento para la preparacion de tioalcanoil-carnitinas. | |
| GB1350333A (en) | Method of producing dimethylamino alcohols | |
| GB1305836A (is") | ||
| GB1510075A (en) | Acid addition salt of a substituted pyrido-dioxin derivative | |
| IE42035L (en) | Isoquinoline derivatives | |
| GB1527941A (en) | 1-(3-phenylpropyl)-4-(beta-alkoxyacryloyl)piperazine derivatives | |
| GB1526172A (en) | Antihypertensive compositions | |
| GB1439108A (en) | Thiono-thiolphosphoric acid esters and their use as insecticides and acaricides | |
| GB1366236A (en) | Fungicidal agents | |
| GB1499054A (en) | Stable chelocardin composition | |
| JPS52113979A (en) | Novel 3,4-dihydrocarbostyril derivatives and method preparing the same | |
| GB1438748A (en) | Thionothiol-phosphoric acid ester and its use as an insecti | |
| GB1500359A (en) | 4-aminopyrimidine derivatives | |
| ES364896A1 (es) | Un procedimiento para la preparacion de un agente para el control de los hongos | |
| GB1455682A (en) | Fungicidal agent |