IL44176A - Azetidine derivatives their preparation and their use in the synthesis of penicillanic and cephalosporanic acid derivatives - Google Patents

Azetidine derivatives their preparation and their use in the synthesis of penicillanic and cephalosporanic acid derivatives

Info

Publication number
IL44176A
IL44176A IL44176A IL4417674A IL44176A IL 44176 A IL44176 A IL 44176A IL 44176 A IL44176 A IL 44176A IL 4417674 A IL4417674 A IL 4417674A IL 44176 A IL44176 A IL 44176A
Authority
IL
Israel
Prior art keywords
group
acid
enyl
azetidin
phenylacetamido
Prior art date
Application number
IL44176A
Other languages
English (en)
Other versions
IL44176A0 (en
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of IL44176A0 publication Critical patent/IL44176A0/xx
Publication of IL44176A publication Critical patent/IL44176A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/08—Preparation by forming the ring or condensed ring systems
    • C07D501/10—Preparation by forming the ring or condensed ring systems from compounds containing the penicillin ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages
IL44176A 1973-02-09 1974-02-08 Azetidine derivatives their preparation and their use in the synthesis of penicillanic and cephalosporanic acid derivatives IL44176A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB657673A GB1465893A (en) 1973-02-09 1973-02-09 I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use

Publications (2)

Publication Number Publication Date
IL44176A0 IL44176A0 (en) 1974-05-16
IL44176A true IL44176A (en) 1977-04-29

Family

ID=9817015

Family Applications (1)

Application Number Title Priority Date Filing Date
IL44176A IL44176A (en) 1973-02-09 1974-02-08 Azetidine derivatives their preparation and their use in the synthesis of penicillanic and cephalosporanic acid derivatives

Country Status (30)

Country Link
US (2) US3966738A (hu)
JP (1) JPS5734836B2 (hu)
AR (1) AR204821A1 (hu)
AT (1) AT331399B (hu)
AU (1) AU6540874A (hu)
BE (1) BE810808A (hu)
BR (1) BR7400904D0 (hu)
CA (1) CA1042873A (hu)
CH (1) CH615675A5 (hu)
CS (1) CS189623B2 (hu)
DD (1) DD111580A5 (hu)
DE (1) DE2406165A1 (hu)
DK (1) DK153949C (hu)
ES (1) ES423051A1 (hu)
FI (1) FI63583C (hu)
FR (1) FR2260583B1 (hu)
GB (1) GB1465893A (hu)
HU (1) HU167925B (hu)
IE (1) IE38833B1 (hu)
IL (1) IL44176A (hu)
IN (1) IN139732B (hu)
IT (1) IT1055549B (hu)
LU (1) LU69361A1 (hu)
NL (1) NL181991C (hu)
NO (1) NO142815C (hu)
PH (1) PH9901A (hu)
RO (1) RO67307A (hu)
SE (1) SE417958B (hu)
YU (1) YU36723B (hu)
ZA (1) ZA74831B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1465893A (en) * 1973-02-09 1977-03-02 Gist Brocades Nv I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use
US4046761A (en) * 1974-02-08 1977-09-06 Gist-Brocades N.V. Process for preparing cephalosporin derivatives
US4159266A (en) * 1974-12-24 1979-06-26 Eli Lilly And Company Method of preparation of 3-methylenecephams
US4018761A (en) * 1975-02-19 1977-04-19 E. R. Squibb & Sons, Inc. Thio-β-lactam cephalosporins
GB1472864A (en) * 1975-04-05 1977-05-11 Farmaceutici Italia Method of preparing cephalosporins
IT1063088B (it) * 1976-06-01 1985-02-11 Dobfar Spa Derivati azetidinonici e procedimento per la preparazione di cefalosporine
US4322347A (en) * 1978-04-03 1982-03-30 Bristol-Myers Company 2-Carbamoyloxymethyl-penicillin derivatives
GB2045236A (en) * 1979-03-26 1980-10-29 Hoechst Uk Ltd Oxapenem derivatives
GB2099817B (en) * 1981-04-10 1985-05-15 Otsuka Kagaku Yakuhin Azetidinone derivatives and process for the preparation of the same
US6383773B2 (en) 1998-04-23 2002-05-07 Massachusetts Institute Of Technology Penicillin conversion

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725399A (en) * 1969-03-11 1973-04-03 Glaxo Lab Ltd METHOD OF PRODUCING 7{62 -ACYLAMIDO-3-METHYLCEPH-3-Em-4-CARBOXYLIC ACID ESTERS
US3853861A (en) * 1969-03-18 1974-12-10 Lilly Co Eli Cephalexin intermediate
GB1312233A (en) * 1969-12-05 1973-04-04 Glaxo Lab Ltd Cephalosporin compounds
US3843637A (en) * 1971-05-11 1974-10-22 Bristol Myers Co Process for rearranging 6-acylamidopenicillanic acid-1-oxides to 7-acyla mido-3-methyl-ceph-3-em-4-carboxylic acids
US3840556A (en) * 1971-05-28 1974-10-08 Lilly Co Eli Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby
US3720666A (en) * 1971-09-02 1973-03-13 American Home Prod 6-(substituted-4-oxouretidino-1-yl)penicillanic acids
US3736318A (en) * 1971-09-09 1973-05-29 American Home Prod 6-(2-substituted-3-phenyl-2h-isoindole-1-carboxamido)penicillanic acids
US3944545A (en) * 1972-05-10 1976-03-16 Eli Lilly And Company Process for preparing desacetoxycephalosporins
GB1431174A (en) * 1972-06-30 1976-04-07 Clin Midy Process for the conversion of a penicillin s-oxide into a corresponding desacetoxycephalosporin
JPS4988892A (hu) * 1972-12-28 1974-08-24
US3962277A (en) * 1973-02-09 1976-06-08 Gist-Brocades N.V. Acetidine derivatives
GB1465893A (en) * 1973-02-09 1977-03-02 Gist Brocades Nv I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use
US4008221A (en) * 1973-11-07 1977-02-15 Richardson-Merrell Inc. 6-[(2,4-Dioxo-1-pyrimidinyl)acylamino]penicillin derivatives
GB1483526A (en) * 1974-02-08 1977-08-24 Gist Brocades Nv Azetidine derivatives
CH602746A5 (hu) * 1974-03-12 1978-07-31 Hoffmann La Roche
DE2440268A1 (de) * 1974-08-22 1976-03-04 Bayer Ag Beta-lactamantibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4009160A (en) * 1974-11-12 1977-02-22 Pfizer Inc. Aminomethylarylmethylpenicillin derivatives
DE2457464A1 (de) * 1974-12-05 1976-06-10 Hoechst Ag Acylaminopenicillansaeuren und verfahren zu ihrer herstellung
US3953440A (en) * 1974-12-13 1976-04-27 Eli Lilly And Company Deacetoxycephalosporins via penicillin sulfoxide rearrangement
JPS5195090A (en) * 1975-02-14 1976-08-20 66 * dd22 * 33 hidorokishipiridajin 44 karubokishiamido * 22 * paraahidorokishifueniru * asetoamido * penishiransanno seiho

Also Published As

Publication number Publication date
SE417958B (sv) 1981-04-27
NL181991C (nl) 1988-06-16
PH9901A (en) 1976-06-08
DK153949C (da) 1989-02-06
AU6540874A (en) 1975-08-14
FR2260583B1 (hu) 1978-12-29
IE38833L (en) 1974-08-09
NO142815C (no) 1980-10-22
AR204821A1 (es) 1976-03-05
DD111580A5 (hu) 1975-02-20
YU33674A (en) 1982-06-18
NO740431L (no) 1974-08-12
ZA74831B (en) 1974-12-24
CA1042873A (en) 1978-11-21
ATA100774A (de) 1975-11-15
FR2260583A1 (hu) 1975-09-05
FI63583B (fi) 1983-03-31
BE810808A (fr) 1974-08-08
AT331399B (de) 1976-08-25
IL44176A0 (en) 1974-05-16
YU36723B (en) 1984-08-31
GB1465893A (en) 1977-03-02
NO142815B (no) 1980-07-14
DE2406165A1 (de) 1974-08-15
JPS49102669A (hu) 1974-09-27
RO67307A (ro) 1981-08-17
ES423051A1 (es) 1976-05-01
IT1055549B (it) 1982-01-11
FI63583C (fi) 1983-07-11
HU167925B (hu) 1976-01-28
DK153949B (da) 1988-09-26
CH615675A5 (hu) 1980-02-15
IE38833B1 (en) 1978-06-07
NL181991B (nl) 1987-07-16
CS189623B2 (en) 1979-04-30
JPS5734836B2 (hu) 1982-07-26
IN139732B (hu) 1976-07-24
LU69361A1 (hu) 1974-05-17
US4282145A (en) 1981-08-04
NL7401730A (hu) 1974-08-13
US3966738A (en) 1976-06-29
BR7400904D0 (pt) 1974-11-05

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