IL296713B2 - Enzymes and their applications - Google Patents

Enzymes and their applications

Info

Publication number
IL296713B2
IL296713B2 IL296713A IL29671322A IL296713B2 IL 296713 B2 IL296713 B2 IL 296713B2 IL 296713 A IL296713 A IL 296713A IL 29671322 A IL29671322 A IL 29671322A IL 296713 B2 IL296713 B2 IL 296713B2
Authority
IL
Israel
Prior art keywords
seq
shc
ambrox
homofarnesol
hac
Prior art date
Application number
IL296713A
Other languages
English (en)
Hebrew (he)
Other versions
IL296713A (en
IL296713B1 (en
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53488772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL296713(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of IL296713A publication Critical patent/IL296713A/en
Publication of IL296713B1 publication Critical patent/IL296713B1/en
Publication of IL296713B2 publication Critical patent/IL296713B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/50Perfumes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/04Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y504/00Intramolecular transferases (5.4)
    • C12Y504/99Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017Squalene--hopene cyclase (5.4.99.17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IL296713A 2015-04-24 2016-04-22 Enzymes and their applications IL296713B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1507207.7A GB201507207D0 (en) 2015-04-24 2015-04-24 Enzymes and applications thereof
PCT/EP2016/058987 WO2016170099A1 (en) 2015-04-24 2016-04-22 Enzymes and applications thereof

Publications (3)

Publication Number Publication Date
IL296713A IL296713A (en) 2022-11-01
IL296713B1 IL296713B1 (en) 2024-10-01
IL296713B2 true IL296713B2 (en) 2025-02-01

Family

ID=53488772

Family Applications (5)

Application Number Title Priority Date Filing Date
IL296713A IL296713B2 (en) 2015-04-24 2016-04-22 Enzymes and their applications
IL315274A IL315274A (en) 2015-04-24 2016-04-22 Enzymes and applications thereof
IL254938A IL254938B (en) 2015-04-24 2017-10-09 Enzymes and their applications
IL276291A IL276291B (en) 2015-04-24 2020-07-26 Enzymes and their applications
IL286785A IL286785B2 (en) 2015-04-24 2021-09-29 Enzymes and applications thereof

Family Applications After (4)

Application Number Title Priority Date Filing Date
IL315274A IL315274A (en) 2015-04-24 2016-04-22 Enzymes and applications thereof
IL254938A IL254938B (en) 2015-04-24 2017-10-09 Enzymes and their applications
IL276291A IL276291B (en) 2015-04-24 2020-07-26 Enzymes and their applications
IL286785A IL286785B2 (en) 2015-04-24 2021-09-29 Enzymes and applications thereof

Country Status (12)

Country Link
US (5) US10472655B2 (enExample)
EP (2) EP3286308B1 (enExample)
JP (4) JP6616426B2 (enExample)
CN (3) CN107567500A (enExample)
CO (1) CO2017010807A2 (enExample)
ES (1) ES2838691T3 (enExample)
GB (1) GB201507207D0 (enExample)
IL (5) IL296713B2 (enExample)
MX (3) MX394537B (enExample)
RU (1) RU2727641C2 (enExample)
SG (2) SG10202104954XA (enExample)
WO (1) WO2016170099A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201507170D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Process
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
CN110325646B (zh) * 2017-02-24 2024-02-09 巴斯夫欧洲公司 制备(3e,7e)-高法尼酸或(3e,7e)-高法尼酸酯的方法
WO2018157021A1 (en) * 2017-02-24 2018-08-30 International Flavors & Fragrances Inc. Squalene hopene cyclase and use thereof for producing ambroxan
EP3476822A1 (en) 2017-10-31 2019-05-01 Givaudan SA Process of making organic compounds
JP2019170350A (ja) * 2018-03-30 2019-10-10 国立大学法人千葉大学 スクアレン消費酵素のスクリーニング方法及びスクアレン−ホペン環化酵素
EP3884022B1 (en) * 2018-11-20 2024-06-12 Unilever Global Ip Limited Detergent composition
GB201902646D0 (en) * 2019-02-27 2019-04-10 Givaudan Sa Process
CN110577961B (zh) * 2019-09-23 2021-05-04 安徽师范大学 一种热稳定性苹果酸脱氢酶基因的构建方法、编码蛋白及其应用
GB201917694D0 (en) 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process
GB201917688D0 (en) * 2019-12-04 2020-01-15 Givaudan Sa SHC enzymes and enzyme variants
GB202005468D0 (en) 2020-04-15 2020-05-27 Givaudan Sa Enzyme-media process
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
CN116348602A (zh) * 2020-09-02 2023-06-27 国际香料和香精公司 角鲨烯何帕烯环化酶衍生物及其用于生产降龙涎香醚的用途
MX2024011115A (es) 2022-03-17 2024-09-18 Givaudan Sa Enzimas escualeno-hopeno-ciclasa (shc) y variantes de enzimas.
WO2023245039A1 (en) 2022-06-15 2023-12-21 International Flavors & Fragrances Inc. Squalene hopene cyclase variants for producing sclareolide
WO2024112870A1 (en) * 2022-11-23 2024-05-30 Conagen Inc. Conversion of homofarnesol to ambroxide
WO2024256472A2 (en) 2023-06-12 2024-12-19 Firmenich Sa Preparation of terpenoid compounds
CN118995880A (zh) * 2024-09-05 2024-11-22 北京国科星联科技有限公司 一种检测唾液酸的方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU910561A1 (ru) * 1980-08-19 1982-03-07 Всесоюзный научно-исследовательский институт синтетических и натуральных душистых веществ Способ получени смеси душистых веществ дитерпеноидного р да
JPS6133184A (ja) * 1984-07-24 1986-02-17 Takasago Corp l−アンブロツクスの製造方法
SU1498767A1 (ru) * 1987-06-04 1989-08-07 Институт Химии Ан Мсср Способ получени ( @ ) 3 @ ,6,6,9 @ -тетраметилпергидронафто [2,1-в]фурана
JPH05186452A (ja) * 1991-12-29 1993-07-27 Kuraray Co Ltd L−アンブロックスの製造方法
DE19524584A1 (de) * 1995-07-06 1997-01-09 Basf Ag Verfahren zur stereoselektiven Herstellung von (-)3a,6,6,9a-Tetramethyl-perhydronaphtho[2,1-b]furan
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
ATE302844T1 (de) * 2001-07-02 2005-09-15 Nordmark Arzneimittel Gmbh & C Verfahren zur aufreinigung eines enzyms und hiernach hergestelltes, aufgereinigtes enzym sowie verwendung des enzyms
AU2003302326A1 (en) 2002-12-02 2004-08-10 The Ohio State University Research Foundation Rapid detection of microorganisms
US20040265850A1 (en) 2002-12-02 2004-12-30 Hua Wang Rapid detection of microorganisms
CN1874749A (zh) 2003-11-04 2006-12-06 宝洁公司 包含残留谐香剂的芳香剂
CN100488940C (zh) * 2004-06-11 2009-05-20 湖南中烟工业有限责任公司 用于制备降龙涎醚或向卷烟烟气释放降龙涎醚的草酸酯及应用
US8507564B2 (en) * 2005-08-04 2013-08-13 Shiseido Co., Ltd. Method for selecting perfume ingredient, method for formulating fragrance, and preference-enhancing agent
JP5236233B2 (ja) 2007-09-04 2013-07-17 花王株式会社 (−)−アンブロキサンの製造方法
EP2438182B1 (de) * 2009-06-05 2018-10-10 Basf Se Biokatalytische herstellung von ambroxan
KR101752514B1 (ko) 2009-06-05 2017-06-29 바스프 에스이 소성 변형성 강성 폴리우레탄 발포체, 접착제 및 피복재를 함유하는 복합 부품
US8932839B2 (en) * 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
ES2925777T3 (es) 2010-11-17 2022-10-19 Basf Se Procedimiento para la ciclación biocatalítica de terpenos y mutantes de ciclasa que pueden usarse en el mismo
KR101251793B1 (ko) 2010-11-26 2013-04-08 현대자동차주식회사 차량내 운전자 실제 얼굴 인증 방법
JP2013132226A (ja) 2011-12-26 2013-07-08 Kao Corp (−)−3a,6,6,9a−テトラメチルドデカヒドロナフト[2,1−b]フランの製造方法
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
EP2838871B1 (de) * 2012-04-16 2016-08-10 Basf Se Verfahren zur herstellung von (3e, 7e)-homofarnesol
JP6429243B2 (ja) 2013-09-05 2018-11-28 国立大学法人 新潟大学 アンブレインの製造方法
GB201318886D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
GB201318894D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements in or relating to organic compounds
GB201507170D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Process
GB201507207D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
CN105037308B (zh) 2015-07-06 2017-06-06 四川中烟工业有限责任公司 一种制备降龙涎香醚的方法
WO2018157021A1 (en) 2017-02-24 2018-08-30 International Flavors & Fragrances Inc. Squalene hopene cyclase and use thereof for producing ambroxan

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VARFOLOMEEV, S. D. ET AL., MOLECULAR POLYMORPHISM OF HUMAN ENZYMES AS THE BASIS OF INDIVIDUAL SENSITIVITY TO DRUGS. SUPERCOMPUTER-ASSISTED MODELING AS A TOOL FOR ANALYSIS OF STRUCTURAL CHANGES AND ENZYMATIC ACTIVITY OF PROTEINS., 30 June 2016 (2016-06-30) *

Also Published As

Publication number Publication date
IL276291A (en) 2020-09-30
IL296713A (en) 2022-11-01
RU2727641C2 (ru) 2020-07-22
RU2017134449A (ru) 2019-05-24
SG10202104954XA (en) 2021-06-29
IL276291B (en) 2021-10-31
IL254938A0 (en) 2017-12-31
CN114438147A (zh) 2022-05-06
MX2022008508A (es) 2022-08-08
US20210254112A1 (en) 2021-08-19
CO2017010807A2 (es) 2018-03-20
IL286785B2 (en) 2023-02-01
JP7213167B2 (ja) 2023-01-26
JP2018513691A (ja) 2018-05-31
JP2025032090A (ja) 2025-03-11
CN107567500A (zh) 2018-01-09
WO2016170099A1 (en) 2016-10-27
EP3286308B1 (en) 2020-10-07
CN121065287A (zh) 2025-12-05
RU2017134449A3 (enExample) 2019-05-24
US11021722B2 (en) 2021-06-01
IL254938B (en) 2020-08-31
IL315274A (en) 2024-10-01
IL286785B (en) 2022-10-01
US20180148751A1 (en) 2018-05-31
MX394537B (es) 2025-03-24
EP3286308A1 (en) 2018-02-28
JP6616426B2 (ja) 2019-12-04
JP7603041B2 (ja) 2024-12-19
IL296713B1 (en) 2024-10-01
MX2022003908A (es) 2022-04-19
SG11201707963YA (en) 2017-11-29
JP2023015116A (ja) 2023-01-31
GB201507207D0 (en) 2015-06-10
JP2020048560A (ja) 2020-04-02
US11466299B2 (en) 2022-10-11
US20230220431A1 (en) 2023-07-13
BR112017022322A2 (pt) 2018-07-17
US20200040369A1 (en) 2020-02-06
US20240368647A1 (en) 2024-11-07
EP3760716A1 (en) 2021-01-06
US10472655B2 (en) 2019-11-12
MX2017013098A (es) 2018-01-26
ES2838691T3 (es) 2021-07-02
US12071645B2 (en) 2024-08-27
IL286785A (en) 2021-10-31

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