RU2727641C2 - Способ получения (-)-амброксида, продукт реакции, содержащий (-)-амброксид, и его применение - Google Patents

Способ получения (-)-амброксида, продукт реакции, содержащий (-)-амброксид, и его применение Download PDF

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RU2727641C2
RU2727641C2 RU2017134449A RU2017134449A RU2727641C2 RU 2727641 C2 RU2727641 C2 RU 2727641C2 RU 2017134449 A RU2017134449 A RU 2017134449A RU 2017134449 A RU2017134449 A RU 2017134449A RU 2727641 C2 RU2727641 C2 RU 2727641C2
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shc
ambroxide
seq
hac
product
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RU2017134449A
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RU2017134449A (ru
RU2017134449A3 (enExample
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Эрик ЭЙХГОРН
Борис ШИЛЛИНГ
Денис ВАЛЕР
Лорэн ФУРАЖ
Эстер ЛОШЭР
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Живодан Са
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/50—Perfumes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
RU2017134449A 2015-04-24 2016-04-22 Способ получения (-)-амброксида, продукт реакции, содержащий (-)-амброксид, и его применение RU2727641C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1507207.7A GB201507207D0 (en) 2015-04-24 2015-04-24 Enzymes and applications thereof
GB1507207.7 2015-04-24
PCT/EP2016/058987 WO2016170099A1 (en) 2015-04-24 2016-04-22 Enzymes and applications thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2020123094A Division RU2836734C1 (ru) 2015-04-24 2016-04-22 Ферменты и их применение

Publications (3)

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RU2017134449A RU2017134449A (ru) 2019-05-24
RU2017134449A3 RU2017134449A3 (enExample) 2019-05-24
RU2727641C2 true RU2727641C2 (ru) 2020-07-22

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RU2017134449A RU2727641C2 (ru) 2015-04-24 2016-04-22 Способ получения (-)-амброксида, продукт реакции, содержащий (-)-амброксид, и его применение

Country Status (12)

Country Link
US (5) US10472655B2 (enExample)
EP (2) EP3760716A1 (enExample)
JP (4) JP6616426B2 (enExample)
CN (3) CN107567500A (enExample)
CO (1) CO2017010807A2 (enExample)
ES (1) ES2838691T3 (enExample)
GB (1) GB201507207D0 (enExample)
IL (5) IL315274A (enExample)
MX (3) MX394537B (enExample)
RU (1) RU2727641C2 (enExample)
SG (2) SG11201707963YA (enExample)
WO (1) WO2016170099A1 (enExample)

Families Citing this family (20)

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GB201507170D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Process
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201618090D0 (en) 2016-10-26 2016-12-07 Givaudan Sa Product
WO2018157021A1 (en) * 2017-02-24 2018-08-30 International Flavors & Fragrances Inc. Squalene hopene cyclase and use thereof for producing ambroxan
US11136611B2 (en) 2017-02-24 2021-10-05 Basf Se Method for the preparation of (3E,7E)-homofarnesic acid or (3E,7E)-homofarnesic acid ester
EP3476822A1 (en) 2017-10-31 2019-05-01 Givaudan SA Process of making organic compounds
JP2019170350A (ja) * 2018-03-30 2019-10-10 国立大学法人千葉大学 スクアレン消費酵素のスクリーニング方法及びスクアレン−ホペン環化酵素
BR112021009807A2 (pt) * 2018-11-20 2021-08-17 Unilever Ip Holdings B.V. composição detergente, método de tratamento de um substrato de tecido e uso de uma enzima isomerase
GB201902646D0 (en) * 2019-02-27 2019-04-10 Givaudan Sa Process
CN110577961B (zh) * 2019-09-23 2021-05-04 安徽师范大学 一种热稳定性苹果酸脱氢酶基因的构建方法、编码蛋白及其应用
GB201917688D0 (en) 2019-12-04 2020-01-15 Givaudan Sa SHC enzymes and enzyme variants
GB201917694D0 (en) 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process
GB202005468D0 (en) 2020-04-15 2020-05-27 Givaudan Sa Enzyme-media process
GB202011823D0 (en) * 2020-07-30 2020-09-16 Givaudan Sa Method
ES3037793T3 (en) * 2020-09-02 2025-10-06 Int Flavors & Fragrances Inc Squalene hopene cyclase derivatives and use thereof for producing ambrox
MX2024011115A (es) 2022-03-17 2024-09-18 Givaudan Sa Enzimas escualeno-hopeno-ciclasa (shc) y variantes de enzimas.
US20250368978A1 (en) 2022-06-15 2025-12-04 International Flavors & Fragrances Inc. Squalene hopene cyclase variants for producing sclareolide
WO2024112870A1 (en) * 2022-11-23 2024-05-30 Conagen Inc. Conversion of homofarnesol to ambroxide
WO2024256472A2 (en) 2023-06-12 2024-12-19 Firmenich Sa Preparation of terpenoid compounds
CN118995880A (zh) * 2024-09-05 2024-11-22 北京国科星联科技有限公司 一种检测唾液酸的方法

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SU1498767A1 (ru) * 1987-06-04 1989-08-07 Институт Химии Ан Мсср Способ получени ( @ ) 3 @ ,6,6,9 @ -тетраметилпергидронафто [2,1-в]фурана
US5616737A (en) * 1995-07-06 1997-04-01 Basf Aktiengesellschaft Stereoselective preparation of (-) 3a,6,6,9a-tetramethyl-perhydronaphtho[2,1-b]furan
JP2009060799A (ja) * 2007-09-04 2009-03-26 Kao Corp （−）−アンブロキサンの製造方法
EP2438182A2 (de) * 2009-06-05 2012-04-11 Basf Se Biokatalytische herstellung von ambroxan
US8507564B2 (en) * 2005-08-04 2013-08-13 Shiseido Co., Ltd. Method for selecting perfume ingredient, method for formulating fragrance, and preference-enhancing agent
US20130273619A1 (en) * 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
US8932839B2 (en) * 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein

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SU1498767A1 (ru) * 1987-06-04 1989-08-07 Институт Химии Ан Мсср Способ получени ( @ ) 3 @ ,6,6,9 @ -тетраметилпергидронафто [2,1-в]фурана
US5616737A (en) * 1995-07-06 1997-04-01 Basf Aktiengesellschaft Stereoselective preparation of (-) 3a,6,6,9a-tetramethyl-perhydronaphtho[2,1-b]furan
US8507564B2 (en) * 2005-08-04 2013-08-13 Shiseido Co., Ltd. Method for selecting perfume ingredient, method for formulating fragrance, and preference-enhancing agent
JP2009060799A (ja) * 2007-09-04 2009-03-26 Kao Corp （−）−アンブロキサンの製造方法
EP2438182A2 (de) * 2009-06-05 2012-04-11 Basf Se Biokatalytische herstellung von ambroxan
US8932839B2 (en) * 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
US20130273619A1 (en) * 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol

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RU2017134449A (ru) 2019-05-24
CN107567500A (zh) 2018-01-09
IL286785B (en) 2022-10-01
JP2023015116A (ja) 2023-01-31
EP3760716A1 (en) 2021-01-06
JP7213167B2 (ja) 2023-01-26
US10472655B2 (en) 2019-11-12
CN114438147A (zh) 2022-05-06
MX394537B (es) 2025-03-24
ES2838691T3 (es) 2021-07-02
IL296713A (en) 2022-11-01
IL296713B1 (en) 2024-10-01
EP3286308A1 (en) 2018-02-28
WO2016170099A1 (en) 2016-10-27
IL296713B2 (en) 2025-02-01
IL286785A (en) 2021-10-31
US20180148751A1 (en) 2018-05-31
US11021722B2 (en) 2021-06-01
CO2017010807A2 (es) 2018-03-20
MX2017013098A (es) 2018-01-26
IL254938B (en) 2020-08-31
IL286785B2 (en) 2023-02-01
JP2025032090A (ja) 2025-03-11
US20210254112A1 (en) 2021-08-19
US20230220431A1 (en) 2023-07-13
US11466299B2 (en) 2022-10-11
BR112017022322A2 (pt) 2018-07-17
US20200040369A1 (en) 2020-02-06
CN121065287A (zh) 2025-12-05
JP6616426B2 (ja) 2019-12-04
GB201507207D0 (en) 2015-06-10
RU2017134449A3 (enExample) 2019-05-24
IL315274A (en) 2024-10-01
JP2020048560A (ja) 2020-04-02
JP2018513691A (ja) 2018-05-31
EP3286308B1 (en) 2020-10-07
US20240368647A1 (en) 2024-11-07
IL276291B (en) 2021-10-31
IL254938A0 (en) 2017-12-31
JP7603041B2 (ja) 2024-12-19
SG11201707963YA (en) 2017-11-29
MX2022003908A (es) 2022-04-19
SG10202104954XA (en) 2021-06-29
US12071645B2 (en) 2024-08-27
IL276291A (en) 2020-09-30
MX2022008508A (es) 2022-08-08

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