IL291926B2 - FGFR2 inhibitors alone or in combination with immunostimulating agents in cancer treatment - Google Patents

FGFR2 inhibitors alone or in combination with immunostimulating agents in cancer treatment

Info

Publication number
IL291926B2
IL291926B2 IL291926A IL29192622A IL291926B2 IL 291926 B2 IL291926 B2 IL 291926B2 IL 291926 A IL291926 A IL 291926A IL 29192622 A IL29192622 A IL 29192622A IL 291926 B2 IL291926 B2 IL 291926B2
Authority
IL
Israel
Prior art keywords
fgfr2
antibody
iiib
cancer
iiib antibody
Prior art date
Application number
IL291926A
Other languages
English (en)
Hebrew (he)
Other versions
IL291926B1 (en
IL291926A (en
Original Assignee
Five Prime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics Inc filed Critical Five Prime Therapeutics Inc
Publication of IL291926A publication Critical patent/IL291926A/en
Publication of IL291926B1 publication Critical patent/IL291926B1/en
Publication of IL291926B2 publication Critical patent/IL291926B2/en

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
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IL291926A 2015-11-23 2016-11-22 FGFR2 inhibitors alone or in combination with immunostimulating agents in cancer treatment IL291926B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562258731P 2015-11-23 2015-11-23
US201662314174P 2016-03-28 2016-03-28
US201662379094P 2016-08-24 2016-08-24
PCT/US2016/063332 WO2017091577A1 (en) 2015-11-23 2016-11-22 Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment

Publications (3)

Publication Number Publication Date
IL291926A IL291926A (en) 2022-06-01
IL291926B1 IL291926B1 (en) 2024-02-01
IL291926B2 true IL291926B2 (en) 2024-06-01

Family

ID=57589165

Family Applications (2)

Application Number Title Priority Date Filing Date
IL291926A IL291926B2 (en) 2015-11-23 2016-11-22 FGFR2 inhibitors alone or in combination with immunostimulating agents in cancer treatment
IL259162A IL259162B (en) 2015-11-23 2018-05-06 Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL259162A IL259162B (en) 2015-11-23 2018-05-06 Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment

Country Status (14)

Country Link
US (4) US20170145103A1 (enExample)
EP (1) EP3380523A1 (enExample)
JP (3) JP7349787B2 (enExample)
KR (2) KR20250034528A (enExample)
CN (2) CN108368174B (enExample)
AU (2) AU2016359609B2 (enExample)
BR (1) BR112018010410A8 (enExample)
CA (1) CA3004794A1 (enExample)
IL (2) IL291926B2 (enExample)
MX (2) MX2018006181A (enExample)
RU (1) RU2745707C2 (enExample)
SG (2) SG10201913538VA (enExample)
TW (2) TWI791422B (enExample)
WO (2) WO2017091577A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS58719B1 (sr) 2013-08-01 2019-06-28 Five Prime Therapeutics Inc Nefukozilisana anti-fgfr2iiib antitela
US10478494B2 (en) 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
CN108368174B (zh) * 2015-11-23 2023-04-14 戊瑞治疗有限公司 用于癌症治疗的单独fgfr2抑制剂或与免疫刺激剂的组合
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KR20250034528A (ko) 2025-03-11
MX2018006181A (es) 2018-09-24
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