IL285722B2 - Dosing regimen of anti-amyloid beta monoclonal antibody for the treatment of Alzheimer's disease - Google Patents

Dosing regimen of anti-amyloid beta monoclonal antibody for the treatment of Alzheimer's disease

Info

Publication number
IL285722B2
IL285722B2 IL285722A IL28572221A IL285722B2 IL 285722 B2 IL285722 B2 IL 285722B2 IL 285722 A IL285722 A IL 285722A IL 28572221 A IL28572221 A IL 28572221A IL 285722 B2 IL285722 B2 IL 285722B2
Authority
IL
Israel
Prior art keywords
antibody
dose
human patient
patient
body weight
Prior art date
Application number
IL285722A
Other languages
English (en)
Hebrew (he)
Other versions
IL285722B1 (en
IL285722A (en
Original Assignee
Biogen Int Neuroscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Int Neuroscience Gmbh filed Critical Biogen Int Neuroscience Gmbh
Publication of IL285722A publication Critical patent/IL285722A/en
Publication of IL285722B1 publication Critical patent/IL285722B1/en
Publication of IL285722B2 publication Critical patent/IL285722B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL285722A 2014-12-02 2015-12-02 Dosing regimen of anti-amyloid beta monoclonal antibody for the treatment of Alzheimer's disease IL285722B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462086674P 2014-12-02 2014-12-02
US201562111874P 2015-02-04 2015-02-04
US201562149133P 2015-04-17 2015-04-17
US201562195119P 2015-07-21 2015-07-21
PCT/IB2015/002465 WO2016087944A2 (en) 2014-12-02 2015-12-02 Method for treating alzheimer's disease

Publications (3)

Publication Number Publication Date
IL285722A IL285722A (en) 2021-09-30
IL285722B1 IL285722B1 (en) 2024-04-01
IL285722B2 true IL285722B2 (en) 2024-08-01

Family

ID=55358010

Family Applications (4)

Application Number Title Priority Date Filing Date
IL285722A IL285722B2 (en) 2014-12-02 2015-12-02 Dosing regimen of anti-amyloid beta monoclonal antibody for the treatment of Alzheimer's disease
IL311405A IL311405A (en) 2014-12-02 2015-12-02 Methods for treating Alzheimer's disease
IL324723A IL324723A (en) 2014-12-02 2015-12-02 Methods for treating alzheimer's disease
IL252433A IL252433B (en) 2014-12-02 2017-05-22 Methods for treating Alzheimer's disease

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL311405A IL311405A (en) 2014-12-02 2015-12-02 Methods for treating Alzheimer's disease
IL324723A IL324723A (en) 2014-12-02 2015-12-02 Methods for treating alzheimer's disease
IL252433A IL252433B (en) 2014-12-02 2017-05-22 Methods for treating Alzheimer's disease

Country Status (12)

Country Link
US (1) US10842871B2 (enExample)
EP (1) EP3227329A2 (enExample)
JP (5) JP2017537905A (enExample)
KR (3) KR20170088360A (enExample)
AU (3) AU2015356773B2 (enExample)
CA (1) CA2967897A1 (enExample)
EA (1) EA201791199A1 (enExample)
IL (4) IL285722B2 (enExample)
MA (1) MA41115A (enExample)
MX (2) MX385045B (enExample)
WO (1) WO2016087944A2 (enExample)
ZA (1) ZA202107358B (enExample)

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