IL267070A - Antibodies against ox40 and their uses - Google Patents
Antibodies against ox40 and their usesInfo
- Publication number
- IL267070A IL267070A IL267070A IL26707019A IL267070A IL 267070 A IL267070 A IL 267070A IL 267070 A IL267070 A IL 267070A IL 26707019 A IL26707019 A IL 26707019A IL 267070 A IL267070 A IL 267070A
- Authority
- IL
- Israel
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3023—Lung
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434761P | 2016-12-15 | 2016-12-15 | |
| PCT/US2017/066680 WO2018112346A1 (en) | 2016-12-15 | 2017-12-15 | Anti-ox40 antibodies and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL267070A true IL267070A (en) | 2019-08-29 |
Family
ID=60937946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL267070A IL267070A (en) | 2016-12-15 | 2019-06-03 | Antibodies against ox40 and their uses |
Country Status (37)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2753493C2 (ru) * | 2016-12-15 | 2021-08-17 | Эббви Байотерапьютикс Инк. | Анти-ох40 антитела и их применение |
| BR112019025913A2 (pt) * | 2017-06-09 | 2020-06-30 | Glaxosmithkline Intellectual Property Development Limited | métodos para tratar câncer em um paciente em necesssidade do mesmo e para produzir um anticorpo, anticorpo anti-icos ou fragmento de ligação ao antígeno do mesmo e um anticorpo anti-ox40 ou fragmento de ligação ao antígeno do mesmo, uso de um anticorpo anti-icos ou porção de ligação ao antígeno do mesmo e um anticorpo anti-ox40 ou porção de ligação ao antígeno do mesmo na fabricação de um medicamento, polinucleotídeo que codifica um anticorpo, vetor, e, célula hospedeira. |
| US11242398B2 (en) * | 2017-08-01 | 2022-02-08 | Remd Biotherapeutics, Inc. | Anti-OX40 antibodies and methods of activating OX40 |
| CN110790837A (zh) * | 2018-08-02 | 2020-02-14 | 上海君实生物医药科技股份有限公司 | 抗btla抗体 |
| WO2020119789A1 (en) * | 2018-12-14 | 2020-06-18 | Wuxi Biologics (Shanghai) Co., Ltd. | Fully human antibodies against ox40, method for preparing the same, and use thereof |
| WO2020132857A1 (zh) * | 2018-12-25 | 2020-07-02 | 杭州翰思生物医药有限公司 | 抗ox40的单克隆抗体及其应用 |
| CN110172090B (zh) * | 2019-06-03 | 2020-04-03 | 中山标佳生物科技有限公司 | Cd134单克隆抗体及其制备方法和癌症治疗中的应用 |
| WO2021098851A1 (en) * | 2019-11-20 | 2021-05-27 | Eucure (Beijing) Biopharma Co., Ltd | Anti-ctla4/ox40 bispecific antibodies and uses thereof |
| MX2022007712A (es) | 2019-12-17 | 2022-09-26 | Amgen Inc | Agonista doble de interleucina-2/receptor de tnf para uso en terapia. |
| CN113045654A (zh) * | 2019-12-27 | 2021-06-29 | 南开大学 | 抗ox40抗体及其用途 |
| CN111303285B (zh) * | 2019-12-27 | 2023-06-02 | 百力司康生物医药(杭州)有限公司 | 靶向ox40的抗体及其制备方法和应用 |
| US20230139700A1 (en) * | 2020-03-23 | 2023-05-04 | Bio-Thera Solutions, Ltd. | Development and application of immune cell activator |
| PE20230682A1 (es) * | 2020-04-17 | 2023-04-21 | Hutchison Medipharma Ltd | Anticuerpo anti-ox40 y usos del mismo |
| TWI802923B (zh) * | 2020-06-30 | 2023-05-21 | 大陸商和鉑醫藥（上海）有限責任公司 | 標靶ｏｘ４０的抗體及其製備方法和應用 |
| WO2022020108A1 (en) * | 2020-07-23 | 2022-01-27 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof |
| CN111704671B (zh) * | 2020-08-19 | 2020-11-24 | 广东赛尔生物科技有限公司 | Ox40抗体及其在治疗癌症中的应用 |
| CN112442121A (zh) * | 2020-08-20 | 2021-03-05 | 山东兴瑞生物科技有限公司 | Ox40抗体、其编码基因、及抗体的制备方法和在增强人体免疫功能中的应用 |
| CN114106173A (zh) * | 2020-08-26 | 2022-03-01 | 上海泰槿生物技术有限公司 | 抗ox40抗体、其药物组合物及应用 |
| CN111763258B (zh) * | 2020-09-01 | 2020-12-29 | 北京百奥赛图基因生物技术有限公司 | 抗ox40抗体及其用途 |
| CN114515335A (zh) * | 2020-11-19 | 2022-05-20 | 百奥泰生物制药股份有限公司 | 抗ox40抗体在治疗肿瘤或癌症中的应用 |
| WO2022117572A2 (en) | 2020-12-02 | 2022-06-09 | Oncurious Nv | An ltbr agonist in combination therapy against cancer |
| KR20230137410A (ko) * | 2021-01-28 | 2023-10-04 | 아스트리아 테라퓨틱스, 인크. | 혈장 칼리크레인 항체 및 이의 용도 |
| CN115260312B (zh) * | 2021-04-30 | 2025-02-14 | 保诺科技（北京）有限公司 | 结合ox40的抗体或抗原结合片段 |
| CN118121694B (zh) * | 2022-12-01 | 2026-03-27 | 北京东方百泰生物科技股份有限公司 | 一种抗Siglec-15单克隆抗体的注射制剂 |
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| RU2753493C2 (ru) * | 2016-12-15 | 2021-08-17 | Эббви Байотерапьютикс Инк. | Анти-ох40 антитела и их применение |
-
2017
- 2017-12-15 RU RU2019121895A patent/RU2753493C2/ru active
- 2017-12-15 CA CA3045940A patent/CA3045940A1/en not_active Abandoned
- 2017-12-15 US US15/843,281 patent/US10556962B2/en active Active
- 2017-12-15 PL PL17826089T patent/PL3504242T3/pl unknown
- 2017-12-15 PE PE2019001249A patent/PE20191403A1/es unknown
- 2017-12-15 MY MYPI2019003403A patent/MY198059A/en unknown
- 2017-12-15 DK DK17826089.9T patent/DK3504242T3/da active
- 2017-12-15 KR KR1020197020437A patent/KR102341926B1/ko not_active Expired - Fee Related
- 2017-12-15 SG SG10201914126RA patent/SG10201914126RA/en unknown
- 2017-12-15 MA MA053184A patent/MA53184A/fr unknown
- 2017-12-15 AU AU2017377036A patent/AU2017377036B2/en not_active Ceased
- 2017-12-15 HR HRP20201259TT patent/HRP20201259T1/hr unknown
- 2017-12-15 HU HUE17826089A patent/HUE050399T2/hu unknown
- 2017-12-15 KR KR1020217041290A patent/KR20210157471A/ko not_active Withdrawn
- 2017-12-15 UA UAA201907981A patent/UA125041C2/uk unknown
- 2017-12-15 PT PT178260899T patent/PT3504242T/pt unknown
- 2017-12-15 ES ES17826089T patent/ES2813057T3/es active Active
- 2017-12-15 SM SM20200462T patent/SMT202000462T1/it unknown
- 2017-12-15 CN CN201780086610.XA patent/CN110573527A/zh active Pending
- 2017-12-15 EP EP17826089.9A patent/EP3504242B1/en active Active
- 2017-12-15 UY UY0001037523A patent/UY37523A/es not_active Application Discontinuation
- 2017-12-15 MX MX2019007121A patent/MX2019007121A/es unknown
- 2017-12-15 JP JP2019531934A patent/JP6772385B2/ja not_active Expired - Fee Related
- 2017-12-15 BR BR112019012328-8A patent/BR112019012328A2/pt not_active Application Discontinuation
- 2017-12-15 SI SI201730380T patent/SI3504242T1/sl unknown
- 2017-12-15 LT LTEP17826089.9T patent/LT3504242T/lt unknown
- 2017-12-15 AR ARP170103527A patent/AR110526A1/es unknown
- 2017-12-15 TW TW106144235A patent/TWI734879B/zh not_active IP Right Cessation
- 2017-12-15 WO PCT/US2017/066680 patent/WO2018112346A1/en not_active Ceased
- 2017-12-15 RS RS20200923A patent/RS60664B1/sr unknown
- 2017-12-15 EP EP20173858.0A patent/EP3725809A1/en not_active Withdrawn
- 2017-12-15 BR BR122020025629-0A patent/BR122020025629B1/pt active IP Right Grant
- 2017-12-15 CR CR20190330A patent/CR20190330A/es unknown
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2018
- 2018-02-28 US US15/908,221 patent/US10040864B2/en active Active
- 2018-08-06 US US16/056,042 patent/US20180346593A1/en not_active Abandoned
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2019
- 2019-06-03 IL IL267070A patent/IL267070A/en unknown
- 2019-06-13 DO DO2019000165A patent/DOP2019000165A/es unknown
- 2019-06-14 PH PH12019501357A patent/PH12019501357A1/en unknown
- 2019-06-14 CL CL2019001646A patent/CL2019001646A1/es unknown
- 2019-07-08 CO CONC2019/0007288A patent/CO2019007288A2/es unknown
- 2019-07-12 EC ECSENADI201950049A patent/ECSP19050049A/es unknown
- 2019-10-24 US US16/663,131 patent/US10604584B2/en active Active
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2020
- 2020-02-20 US US16/796,622 patent/US20200181282A1/en not_active Abandoned
- 2020-08-21 CY CY20201100785T patent/CY1123274T1/el unknown
- 2020-09-29 JP JP2020162944A patent/JP2021019603A/ja active Pending
- 2020-10-02 US US17/062,474 patent/US20210017289A1/en not_active Abandoned
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2021
- 2021-12-23 US US17/560,664 patent/US20220112304A1/en not_active Abandoned
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