IL251860A0 - Dithyroaryl histone deacetylase inhibitors and their use in therapy - Google Patents

Dithyroaryl histone deacetylase inhibitors and their use in therapy

Info

Publication number
IL251860A0
IL251860A0 IL251860A IL25186017A IL251860A0 IL 251860 A0 IL251860 A0 IL 251860A0 IL 251860 A IL251860 A IL 251860A IL 25186017 A IL25186017 A IL 25186017A IL 251860 A0 IL251860 A0 IL 251860A0
Authority
IL
Israel
Prior art keywords
diheteroaryl
therapy
histone deacetylase
deacetylase inhibitors
inhibitors
Prior art date
Application number
IL251860A
Other languages
English (en)
Hebrew (he)
Original Assignee
Karus Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karus Therapeutics Ltd filed Critical Karus Therapeutics Ltd
Publication of IL251860A0 publication Critical patent/IL251860A0/en

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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
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  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
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  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
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  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL251860A 2014-10-29 2017-04-23 Dithyroaryl histone deacetylase inhibitors and their use in therapy IL251860A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1419228.0A GB201419228D0 (en) 2014-10-29 2014-10-29 Compounds
PCT/GB2015/053260 WO2016067040A1 (en) 2014-10-29 2015-10-29 Diheteroaryl histone deacetylase inhibitors and their use in therapy

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EP (1) EP3212625A1 (cg-RX-API-DMAC7.html)
JP (1) JP2017532357A (cg-RX-API-DMAC7.html)
KR (1) KR20170081194A (cg-RX-API-DMAC7.html)
CN (1) CN107001340A (cg-RX-API-DMAC7.html)
AU (1) AU2015340305B2 (cg-RX-API-DMAC7.html)
BR (1) BR112017008794A2 (cg-RX-API-DMAC7.html)
CA (1) CA2966072A1 (cg-RX-API-DMAC7.html)
GB (1) GB201419228D0 (cg-RX-API-DMAC7.html)
IL (1) IL251860A0 (cg-RX-API-DMAC7.html)
MX (1) MX2017005422A (cg-RX-API-DMAC7.html)
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Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
NZ707366A (en) 2012-11-07 2018-11-30 Karus Therapeutics Ltd Novel histone deacetylase inhibitors and their use in therapy
NZ714283A (en) 2013-05-10 2020-04-24 Karus Therapeutics Ltd Novel histone deacetylase inhibitors
GB201419228D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
GB201419264D0 (en) 2014-10-29 2014-12-10 Karus Therapeutics Ltd Compounds
EP3230259B1 (en) 2014-12-08 2024-04-03 The Research Foundation for The State University of New York Anti-fungals targeting the synthesis of fungal shingolipids
US11414378B2 (en) 2017-06-16 2022-08-16 The Research Foundation For The State University Of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
JP2022538284A (ja) 2019-06-27 2022-09-01 ザ ジョージ ワシントン ユニバーシティ， ア コングレッショナリー チャータード ノット－フォー－プロフィット コーポレイション Ｈｄａｃ６活性化マクロファージ、その組成物および使用
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AU2015340305B2 (en) 2018-12-06
CN107001340A (zh) 2017-08-01
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EP3212625A1 (en) 2017-09-06
MX2017005422A (es) 2017-08-24
WO2016067040A1 (en) 2016-05-06
CA2966072A1 (en) 2016-05-06
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JP2017532357A (ja) 2017-11-02
BR112017008794A2 (pt) 2017-12-26

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