IL236131A0 - Camsylate salt - Google Patents

Camsylate salt

Info

Publication number
IL236131A0
IL236131A0 IL236131A IL23613114A IL236131A0 IL 236131 A0 IL236131 A0 IL 236131A0 IL 236131 A IL236131 A IL 236131A IL 23613114 A IL23613114 A IL 23613114A IL 236131 A0 IL236131 A0 IL 236131A0
Authority
IL
Israel
Prior art keywords
camsylate salt
camsylate
salt
Prior art date
Application number
IL236131A
Other languages
English (en)
Hebrew (he)
Original Assignee
Astrazeneca Ab
Bohlin Martin Hans
Stewart Craig Robert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Bohlin Martin Hans, Stewart Craig Robert filed Critical Astrazeneca Ab
Publication of IL236131A0 publication Critical patent/IL236131A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL236131A 2012-06-21 2014-12-08 Camsylate salt IL236131A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261662592P 2012-06-21 2012-06-21
PCT/GB2013/051606 WO2013190302A1 (en) 2012-06-21 2013-06-20 Camsylate salt

Publications (1)

Publication Number Publication Date
IL236131A0 true IL236131A0 (en) 2015-02-01

Family

ID=48746084

Family Applications (1)

Application Number Title Priority Date Filing Date
IL236131A IL236131A0 (en) 2012-06-21 2014-12-08 Camsylate salt

Country Status (42)

Country Link
US (1) US10548882B2 (en:Method)
EP (2) EP3064494A1 (en:Method)
JP (2) JP2015520221A (en:Method)
KR (1) KR102123708B1 (en:Method)
CN (2) CN106279102A (en:Method)
AP (2) AP2014008137A0 (en:Method)
AR (2) AR091495A1 (en:Method)
AU (2) AU2013279109B2 (en:Method)
BR (2) BR112014031531B1 (en:Method)
CA (1) CA2875589C (en:Method)
CL (1) CL2014003374A1 (en:Method)
CO (1) CO7151486A2 (en:Method)
CR (2) CR20140571A (en:Method)
CY (1) CY1119505T1 (en:Method)
DK (1) DK2864316T3 (en:Method)
DO (1) DOP2014000268A (en:Method)
EC (1) ECSP14032215A (en:Method)
ES (1) ES2618939T3 (en:Method)
HR (1) HRP20170359T1 (en:Method)
HU (1) HUE033376T2 (en:Method)
IL (1) IL236131A0 (en:Method)
IN (1) IN2014DN10088A (en:Method)
LT (1) LT2864316T (en:Method)
MA (2) MA39259B1 (en:Method)
ME (1) ME02633B (en:Method)
MX (1) MX354214B (en:Method)
NI (1) NI201400146A (en:Method)
NZ (2) NZ727045A (en:Method)
PE (1) PE20150670A1 (en:Method)
PH (2) PH12014502803B1 (en:Method)
PL (1) PL2864316T3 (en:Method)
PT (1) PT2864316T (en:Method)
RS (1) RS55815B1 (en:Method)
RU (1) RU2638175C2 (en:Method)
SG (1) SG11201407934UA (en:Method)
SI (1) SI2864316T1 (en:Method)
SM (1) SMT201700142T1 (en:Method)
TN (1) TN2014000491A1 (en:Method)
TW (2) TWI588140B (en:Method)
UA (1) UA114196C2 (en:Method)
WO (1) WO2013190302A1 (en:Method)
ZA (1) ZA201500408B (en:Method)

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US8415483B2 (en) 2010-12-22 2013-04-09 Astrazeneca Ab Compounds and their use as BACE inhibitors
US9650336B2 (en) 2011-10-10 2017-05-16 Astrazeneca Ab Mono-fluoro beta-secretase inhibitors
US9000182B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab 2H-imidazol-4-amine compounds and their use as BACE inhibitors
US9000184B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-naphthalene-1′,2″-imidazol compounds and their use as BACE inhibitors
US9000183B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-indene-1′,2″-imidazol compounds and their use as BACE inhibitors
US9000185B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cycloalkyl ether compounds and their use as BACE inhibitors
AR102202A1 (es) 2014-10-07 2017-02-08 Astrazeneca Ab Compuestos de oxazol y su uso como inhibidores de bace de oxazol
JP6546410B2 (ja) * 2015-02-23 2019-07-17 ローム株式会社 電力供給装置、acアダプタ、acチャージャ、電子機器および電力供給システム
CN109195630A (zh) * 2016-03-15 2019-01-11 阿斯利康(瑞典)有限公司 用于治疗与淀粉样蛋白β累积相关的病症的BACE抑制剂和抗体或抗原结合片段的组合
TW201740944A (zh) 2016-03-15 2017-12-01 美國禮來大藥廠 組合療法
CA3131753A1 (en) 2019-03-14 2020-09-17 Astrazeneca Ab Lanabecestat for weight loss

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JP4273406B2 (ja) 2001-06-01 2009-06-03 小野薬品工業株式会社 アルドース還元酵素阻害剤を有効成分とする脱髄性疾患または脱髄を伴う疾患治療剤
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WO2009100169A1 (en) 2008-02-06 2009-08-13 Glaxo Group Limited Dual pharmacophores - pde4-muscarinic antagonistics
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US8450308B2 (en) 2008-08-19 2013-05-28 Vitae Pharmaceuticals, Inc. Inhibitors of beta-secretase
CA2736130C (en) 2008-09-11 2014-01-14 Amgen Inc. Spiro-tetracyclic ring compounds as beta-secretase modulators and methods of use
BRPI1009333B8 (pt) 2009-03-13 2021-05-25 Boehringer Ingelheim Int compostos inibidores de beta-secretase, seus usos, bem como composição farmacêutica
UY32750A (es) 2009-07-02 2011-01-31 Astrazeneca Ab Imidazoles sustituidos y uso de los mismos
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JP5828848B2 (ja) 2010-02-24 2015-12-09 ヴァイティー ファーマシューティカルズ,インコーポレイテッド ベータセクレターゼインヒビター
US20120065195A1 (en) 2010-03-31 2012-03-15 Clark Christopher T Compounds for treating neurodegenerative diseases
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WO2012040641A2 (en) 2010-09-24 2012-03-29 Array Biopharma Inc. Compounds for treating neurodegenerative diseases
AR083953A1 (es) 2010-11-22 2013-04-10 Array Biopharma Inc Compuestos para tratar enfermedades neurodegenerativas
US8415483B2 (en) * 2010-12-22 2013-04-09 Astrazeneca Ab Compounds and their use as BACE inhibitors
US9650336B2 (en) 2011-10-10 2017-05-16 Astrazeneca Ab Mono-fluoro beta-secretase inhibitors
US9000185B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cycloalkyl ether compounds and their use as BACE inhibitors
US9000184B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-naphthalene-1′,2″-imidazol compounds and their use as BACE inhibitors
US9000182B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab 2H-imidazol-4-amine compounds and their use as BACE inhibitors
US9000183B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-indene-1′,2″-imidazol compounds and their use as BACE inhibitors

Also Published As

Publication number Publication date
ES2618939T3 (es) 2017-06-22
PH12014502803A1 (en) 2015-02-23
MA37666B1 (fr) 2016-12-30
UA114196C2 (uk) 2017-05-10
KR20150023388A (ko) 2015-03-05
JP2015520221A (ja) 2015-07-16
RU2014148305A (ru) 2016-08-10
AR105176A2 (es) 2017-09-13
CL2014003374A1 (es) 2015-02-27
MX354214B (es) 2018-02-19
AP2017009693A0 (en) 2017-01-31
HK1206349A1 (en) 2016-01-08
KR102123708B1 (ko) 2020-06-16
JP2018104448A (ja) 2018-07-05
PE20150670A1 (es) 2015-06-03
DOP2014000268A (es) 2015-04-15
RU2638175C2 (ru) 2017-12-12
MX2014014709A (es) 2015-03-04
AU2013279109B2 (en) 2017-08-31
CN106279102A (zh) 2017-01-04
EP2864316A1 (en) 2015-04-29
PH12016500498A1 (en) 2017-04-10
ECSP14032215A (es) 2015-12-31
LT2864316T (lt) 2017-03-27
EP2864316B1 (en) 2016-12-14
TWI588140B (zh) 2017-06-21
SI2864316T1 (sl) 2017-04-26
WO2013190302A1 (en) 2013-12-27
CN104411697A (zh) 2015-03-11
MA39259B1 (fr) 2018-09-28
AU2013279109A1 (en) 2015-01-15
CA2875589A1 (en) 2013-12-27
DK2864316T3 (en) 2017-03-20
TW201730177A (zh) 2017-09-01
CO7151486A2 (es) 2014-12-29
ZA201500408B (en) 2016-10-26
PH12014502803B1 (en) 2015-02-23
JP6509393B2 (ja) 2019-05-08
BR122016014302B1 (pt) 2022-08-23
TWI639591B (zh) 2018-11-01
TW201406745A (zh) 2014-02-16
BR112014031531B1 (pt) 2022-08-02
HRP20170359T1 (hr) 2017-05-05
BR112014031531A2 (pt) 2017-06-27
NZ702742A (en) 2016-12-23
ME02633B (me) 2017-06-20
BR122016014302A2 (pt) 2019-08-27
AR091495A1 (es) 2015-02-11
CR20140571A (es) 2015-02-04
SG11201407934UA (en) 2015-01-29
MA39259A1 (fr) 2017-12-29
RS55815B1 (sr) 2017-08-31
AU2017254965A1 (en) 2017-11-23
US10548882B2 (en) 2020-02-04
MA37666A1 (fr) 2016-04-29
TN2014000491A1 (en) 2016-03-30
AU2017254965B2 (en) 2019-05-09
HUE033376T2 (en) 2017-11-28
CN104411697B (zh) 2016-08-10
AP2014008137A0 (en) 2014-12-31
CY1119505T1 (el) 2018-03-07
CR20160202A (es) 2016-07-26
EP3064494A1 (en) 2016-09-07
PT2864316T (pt) 2017-02-24
SMT201700142T1 (it) 2017-05-08
NI201400146A (es) 2016-09-21
CA2875589C (en) 2020-08-25
US20140031379A1 (en) 2014-01-30
IN2014DN10088A (en:Method) 2015-08-21
NZ727045A (en) 2018-06-29
PL2864316T3 (pl) 2017-09-29

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