IL22869A - A benzodiazepine derivative and process for the manufacture thereof - Google Patents

A benzodiazepine derivative and process for the manufacture thereof

Info

Publication number
IL22869A
IL22869A IL22869A IL2286965A IL22869A IL 22869 A IL22869 A IL 22869A IL 22869 A IL22869 A IL 22869A IL 2286965 A IL2286965 A IL 2286965A IL 22869 A IL22869 A IL 22869A
Authority
IL
Israel
Prior art keywords
acid
acid addition
process according
manufacture
addition salts
Prior art date
Application number
IL22869A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23348328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL22869(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL22869A publication Critical patent/IL22869A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Multicomponent Fibers (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Supply And Distribution Of Alternating Current (AREA)
IL22869A 1964-02-11 1965-01-29 A benzodiazepine derivative and process for the manufacture thereof IL22869A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US343941A US3299053A (en) 1964-02-11 1964-02-11 Novel 1-and/or 4-substituted alkyl 5-aromatic-3h-1, 4-benzodiazepines and benzodiazepine-2-ones

Publications (1)

Publication Number Publication Date
IL22869A true IL22869A (en) 1968-11-27

Family

ID=23348328

Family Applications (4)

Application Number Title Priority Date Filing Date
IL22869A IL22869A (en) 1964-02-11 1965-01-29 A benzodiazepine derivative and process for the manufacture thereof
IL22902A IL22902A (en) 1964-02-11 1965-02-03 Benzodiazepine derivatives and process for the manufacture thereof
IL22903A IL22903A (en) 1964-02-11 1965-02-03 Benzodiazepine derivatives and processes for the manufacture thereof
IL22935A IL22935A (en) 1964-02-11 1965-02-08 Benzodiazepine derivatives and process for the manufacture thereof

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL22902A IL22902A (en) 1964-02-11 1965-02-03 Benzodiazepine derivatives and process for the manufacture thereof
IL22903A IL22903A (en) 1964-02-11 1965-02-03 Benzodiazepine derivatives and processes for the manufacture thereof
IL22935A IL22935A (en) 1964-02-11 1965-02-08 Benzodiazepine derivatives and process for the manufacture thereof

Country Status (13)

Country Link
US (1) US3299053A (xx)
BE (4) BE659444A (xx)
BR (4) BR6567053D0 (xx)
CH (4) CH460793A (xx)
DE (4) DE1545933A1 (xx)
DK (3) DK118249B (xx)
ES (4) ES309168A1 (xx)
FR (6) FR4123M (xx)
GB (4) GB1077358A (xx)
IL (4) IL22869A (xx)
NL (4) NL6501578A (xx)
NO (3) NO117367B (xx)
SE (4) SE309597B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO120269B (xx) * 1965-11-02 1970-09-28 Hoffmann La Roche
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation
US3506404A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in blood
US3506403A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in fluids
US3609146A (en) * 1968-11-01 1971-09-28 Sandoz Ag Substituted benzodiazepinone derivatives
IL33961A (en) * 1969-03-13 1973-03-30 Sparamedica Ag Benzodiazepine aminoalkyl carboxylates,their preparation and pharmaceutical compositions containing them
US3691157A (en) * 1970-08-12 1972-09-12 Rodney Ian Fryer Preparation of 7-substituted-1-(2-diethylaminoethyl)-5-(2-halophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-ones
AT314541B (de) * 1970-10-19 1974-04-10 Sumitomo Chemical Co Verfahren zur Herstellung von neuen Benzodiazepinen und ihren Salzen
US3678038A (en) * 1971-04-01 1972-07-18 Hoffmann La Roche 1,4-benzodiazepin-5-ones and methods for the preparation thereof
US3856802A (en) * 1971-05-10 1974-12-24 Upjohn Co 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES
US3872089A (en) * 1971-05-14 1975-03-18 Hoffmann La Roche Substituted thienodiazepines
US4008223A (en) * 1971-12-09 1977-02-15 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
USRE31071E (en) * 1971-12-09 1982-11-02 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
US3859276A (en) * 1972-12-13 1975-01-07 Merck & Co Inc 7-chloro-1,3-dihydro-5-2-polyfluoroalkoxyphenyl)-2h-1,4-benzodiazepin-2-ones
GB1414370A (en) * 1973-08-24 1975-11-19 Grindstedvaerket As Benzodiazepines and their production
US4232016A (en) * 1974-12-20 1980-11-04 Merck Patent Gesellschaft Mit Beschraenkter Haftung 3-Fluorobenzodiazepines
US4246270A (en) * 1976-05-26 1981-01-20 E. I. Du Pont De Nemours And Company 3-Fluorobenzodiazepines and compositions and uses thereof
FI783743A (fi) * 1977-12-14 1979-06-15 Gerot Pharmazeutika Foerfarande foer framstaellning av 3-di-n-propyl-acetoxi-benzodiazepin-2-oner
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
KR20100017766A (ko) 2007-05-10 2010-02-16 에이엠알 테크놀로지, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤조-1,4-디아제핀 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 이의 용도
US20090258865A1 (en) * 2008-03-28 2009-10-15 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
PL3415139T3 (pl) 2011-06-14 2022-07-11 Neurelis, Inc. Podawanie benzodiazepiny

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3109843A (en) * 1963-11-05 Process for preparing
US3121076A (en) * 1964-02-11 Benzodiazepinones and processes
US2461038A (en) * 1947-05-15 1949-02-08 Searle & Co Chemical compositions and the preparation thereof
US2532292A (en) * 1947-12-12 1950-12-05 Searle & Co Diarylmethyl ethers of amino alkanols
US2576106A (en) * 1948-07-13 1951-11-27 Searle & Co N-dicyclohexyl, dialkylaminoalkanamides
US2687414A (en) * 1948-11-26 1954-08-24 Searle & Co Method for producing aromatic aminoalkyl amines

Also Published As

Publication number Publication date
FR4123M (xx) 1966-04-25
ES309167A2 (es) 1965-10-01
BR6567055D0 (pt) 1973-08-02
FR1443116A (fr) 1966-06-24
FR4138M (xx) 1966-05-02
DK105984C (da) 1966-12-05
ES309168A1 (es) 1965-10-01
ES309169A1 (es) 1965-10-16
DK107032C (da) 1967-04-17
DE1545935A1 (de) 1969-12-11
BE659442A (xx) 1965-08-09
NL6501632A (xx) 1965-08-12
DE1545934A1 (de) 1970-10-22
BR6567054D0 (pt) 1973-08-14
NO117367B (xx) 1969-08-04
IL22902A (en) 1969-01-29
US3299053A (en) 1967-01-17
DE1545933A1 (de) 1969-12-18
BE659444A (xx) 1965-08-09
GB1077358A (en) 1967-07-26
IL22935A (en) 1969-11-30
ES309170A1 (es) 1965-07-16
FR4772M (xx) 1967-01-23
FR1455059A (fr) 1966-10-07
IL22903A (en) 1969-03-27
BR6567053D0 (pt) 1973-12-26
DE1545936A1 (de) 1969-12-18
GB1051795A (xx)
CH460030A (de) 1968-07-31
GB1052144A (xx)
GB1098242A (en) 1968-01-10
DE1545936B2 (de) 1975-09-18
NO119798B (xx) 1970-07-06
SE307953B (xx) 1969-01-27
BR6567051D0 (pt) 1973-08-14
SE321477B (xx) 1970-03-09
CH458372A (de) 1968-06-30
FR4609M (xx) 1966-11-21
CH460793A (de) 1968-08-15
NL6501579A (xx) 1965-08-12
BE659443A (xx) 1965-08-09
BE659445A (xx) 1965-08-09
SE307952B (xx) 1969-01-27
NO118273B (xx) 1969-12-08
NL6501578A (xx) 1965-08-12
SE309597B (xx) 1969-03-31
NL6501631A (xx) 1965-08-12
NL141781B (nl) 1974-04-16
DK118249B (da) 1970-07-27
CH467787A (de) 1969-01-31

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