IL214833A - Nuclear reprogramming material - Google Patents
Nuclear reprogramming materialInfo
- Publication number
- IL214833A IL214833A IL214833A IL21483311A IL214833A IL 214833 A IL214833 A IL 214833A IL 214833 A IL214833 A IL 214833A IL 21483311 A IL21483311 A IL 21483311A IL 214833 A IL214833 A IL 214833A
- Authority
- IL
- Israel
- Prior art keywords
- nuclear reprogramming
- reprogramming substance
- substance
- nuclear
- reprogramming
- Prior art date
Links
- 230000008672 reprogramming Effects 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20885309P | 2009-02-27 | 2009-02-27 | |
| US27612309P | 2009-09-08 | 2009-09-08 | |
| PCT/JP2010/053024 WO2010098419A1 (en) | 2009-02-27 | 2010-02-19 | Novel nuclear reprogramming substance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL214833A0 IL214833A0 (en) | 2011-11-30 |
| IL214833A true IL214833A (en) | 2016-07-31 |
Family
ID=42665623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL214833A IL214833A (en) | 2009-02-27 | 2011-08-25 | Nuclear reprogramming material |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8951801B2 (OSRAM) |
| EP (2) | EP2607476B1 (OSRAM) |
| JP (1) | JP5553289B2 (OSRAM) |
| KR (1) | KR101764100B1 (OSRAM) |
| CN (1) | CN102388136B (OSRAM) |
| CA (1) | CA2753845C (OSRAM) |
| IL (1) | IL214833A (OSRAM) |
| SG (1) | SG173876A1 (OSRAM) |
| WO (1) | WO2010098419A1 (OSRAM) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010098419A1 (en) | 2009-02-27 | 2010-09-02 | Kyoto University | Novel nuclear reprogramming substance |
| CA2789749C (en) * | 2010-02-16 | 2018-09-04 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| WO2012074106A1 (ja) | 2010-12-03 | 2012-06-07 | 国立大学法人京都大学 | 多能性幹細胞からの好酸球の製造方法 |
| EP2647699B1 (en) * | 2010-12-03 | 2020-04-01 | Kyoto University | Efficient method for establishing induced pluripotent stem cells |
| EP2695894B1 (en) | 2011-04-08 | 2017-11-01 | Osaka University | Modified laminin and use thereof |
| WO2012141181A1 (ja) * | 2011-04-11 | 2012-10-18 | 国立大学法人京都大学 | 核初期化物質 |
| KR101334404B1 (ko) * | 2011-04-28 | 2013-12-12 | 포항공과대학교 산학협력단 | 배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법 |
| KR101791926B1 (ko) | 2011-07-25 | 2017-11-20 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도 만능 줄기 세포 스크리닝 방법 |
| US20140248698A1 (en) | 2011-10-21 | 2014-09-04 | Arkray, Inc. | Method for culturing pluripotency-maintained singly dispersed cells by means of laminar flow |
| EP2784153B1 (en) | 2011-11-25 | 2018-01-03 | Kyoto University | Method for culturing pluripotent stem cell |
| EP2852671B1 (en) * | 2012-05-21 | 2018-08-22 | The Regents of the University of California | Generation of human ips cells by a synthetic self- replicative rna |
| US20160002599A1 (en) | 2013-02-08 | 2016-01-07 | Kyoto University | Production methods for megakaryocytes and platelets |
| US9738861B2 (en) | 2013-03-06 | 2017-08-22 | Kyoto University | Culture system for pluripotent stem cells and method for subculturing pluripotent stem cells |
| US10519421B2 (en) | 2013-03-21 | 2019-12-31 | Kyoto University | Induction of motor neurons from pluripotent stem cells |
| JP6473686B2 (ja) | 2013-03-25 | 2019-02-20 | 公益財団法人神戸医療産業都市推進機構 | 細胞の選別方法 |
| JP6461787B2 (ja) | 2013-04-12 | 2019-01-30 | 国立大学法人京都大学 | 肺胞上皮前駆細胞の誘導方法 |
| EP2998391B1 (en) | 2013-05-14 | 2020-02-19 | Kyoto University | Efficient myocardial cell induction method |
| KR101870174B1 (ko) | 2013-05-31 | 2018-06-22 | 아이하트 재팬 가부시키가이샤 | 하이드로겔을 포함하는 적층화된 세포 시트 |
| MX2015017036A (es) | 2013-06-11 | 2016-07-21 | Univ Kyoto | Metodo para producir celulas progenitoras renales y farmaco que comprende las mismas. |
| US10557120B2 (en) | 2013-07-26 | 2020-02-11 | Kyoto Prefectural Public University Corporation | Osteoblast and method for preparing same |
| EP3031905A4 (en) | 2013-08-07 | 2017-04-26 | Kyoto University | Method for producing pancreatic hormone-producing cell |
| CN121136933A (zh) | 2013-09-05 | 2025-12-16 | 国立大学法人京都大学 | 由多能干细胞制造产多巴胺神经前体细胞的方法、产多巴胺神经前体细胞、帕金森病治疗剂和试剂盒 |
| EP3064577B1 (en) | 2013-11-01 | 2020-09-09 | Kyoto University | Novel chondrocyte induction method |
| EP3929302A1 (en) | 2014-07-14 | 2021-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method for identifying epitope on protein |
| CN107075484B (zh) | 2014-07-18 | 2022-01-28 | 国立大学法人京都大学 | 从多能性干细胞诱导细胞免疫治疗用t细胞的方法 |
| US10711249B2 (en) | 2014-12-26 | 2020-07-14 | Kyoto University | Method for inducing hepatocytes |
| EP3081638A1 (en) | 2015-04-16 | 2016-10-19 | Kyoto University | Method for producing pseudo-islets |
| WO2017059241A1 (en) | 2015-10-02 | 2017-04-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Lentiviral protein delivery system for rna-guided genome editing |
| AU2017248985B2 (en) | 2016-04-15 | 2023-01-12 | Kyoto University | Method for inducing antigen specific CD8 positive T cells |
| CN109072198B (zh) | 2016-04-22 | 2022-08-26 | 国立大学法人京都大学 | 产多巴胺神经祖细胞的制备方法 |
| KR102537361B1 (ko) | 2016-12-27 | 2023-05-26 | 스미또모 가가꾸 가부시키가이샤 | 인공 다능성 줄기 세포의 평가 방법 및 선발 방법, 그리고 인공 다능성 줄기 세포의 제조 방법 |
| CN110199017A (zh) | 2017-01-20 | 2019-09-03 | 国立大学法人京都大学 | CD8α+β+细胞毒性T细胞的制备方法 |
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| JP7171055B2 (ja) | 2017-03-14 | 2022-11-15 | 国立大学法人京都大学 | 多能性幹細胞からヘルパーｔ細胞を製造する方法 |
| JP7161775B2 (ja) | 2017-05-25 | 2022-10-27 | 国立大学法人京都大学 | 中間中胚葉細胞から腎前駆細胞への分化誘導方法、および多能性幹細胞から腎前駆細胞への分化誘導方法 |
| CN111164209A (zh) | 2017-06-19 | 2020-05-15 | 公益财团法人神户医疗产业都市推进机构 | 多能干细胞的分化能力的预测方法和用于该预测方法的试剂 |
| JP7140400B2 (ja) | 2017-10-17 | 2022-09-21 | 国立大学法人京都大学 | 多能性幹細胞から人工神経筋接合部を得る方法 |
| WO2020013315A1 (ja) | 2018-07-13 | 2020-01-16 | 国立大学法人京都大学 | γδＴ細胞の製造方法 |
| JP7285015B2 (ja) | 2018-07-19 | 2023-06-01 | 国立大学法人京都大学 | 多能性幹細胞由来の板状軟骨およびその製造方法 |
| EP3828262A4 (en) | 2018-07-23 | 2022-03-30 | Kyoto University | Novel renal progenitor cell marker and method for concentrating renal progenitor cells using same |
| WO2020116606A1 (ja) | 2018-12-06 | 2020-06-11 | キリンホールディングス株式会社 | Ｔ細胞又はｎｋ細胞の製造方法、ｔ細胞又はｎｋ細胞の培養用培地、ｔ細胞又はｎｋ細胞の培養方法、未分化ｔ細胞の未分化状態を維持する方法及びｔ細胞又はｎｋ細胞の増殖促進剤 |
| US12435311B2 (en) | 2018-12-21 | 2025-10-07 | The University Of Osaka | Lubricin-localized cartilage-like tissue, method for producing same and composition comprising same for treating articular cartilage damage |
| CN113226475A (zh) | 2018-12-26 | 2021-08-06 | 麒麟控股株式会社 | 改造tcr及其制造方法 |
| JP7692610B2 (ja) | 2019-02-26 | 2025-06-16 | 国立大学法人東北大学 | ｉＰＳ細胞を用いた骨芽細胞塊の作製法 |
| KR20220008894A (ko) | 2019-05-15 | 2022-01-21 | 아지노모토 가부시키가이샤 | 신경제세포 또는 각막 상피 세포의 순화 방법 |
| JPWO2020235319A1 (OSRAM) | 2019-05-20 | 2020-11-26 | ||
| JP7058431B2 (ja) | 2019-12-12 | 2022-04-22 | 国立大学法人千葉大学 | 巨核球および血小板を含む凍結乾燥製剤 |
| BR112022017216A2 (pt) | 2020-02-28 | 2022-10-11 | Takeda Pharmaceuticals Co | Método para produzir células exterminadoras naturais a partir de células-tronco pluripotentes |
| WO2021256522A1 (ja) | 2020-06-17 | 2021-12-23 | 国立大学法人京都大学 | キメラ抗原受容体発現免疫担当細胞 |
| US20230256024A1 (en) | 2020-07-13 | 2023-08-17 | Kyoto University | Skeletal muscle precursor cells and method for purifying same, composition for treating myogenic diseases, and method for producing cell group containing skeletal muscle precursor cells |
| EP4180514A4 (en) | 2020-07-20 | 2024-09-04 | Aichi Medical University | COMPOSITION FOR UNDIFFERENTIATED MAINTENANCE CULTURE OF PLURIPOTENT CELLS, MEDIUM FOR UNDIFFERENTIATED MAINTENANCE CULTURE OF PLURIPOTENT CELLS, METHOD FOR MAINTENANCE CULTURE IN UNDIFFERENTIATED STATE OF PLURIPOTENT CELLS, AND METHOD FOR PRODUCING PLURIPOTENT CELLS |
| JPWO2022039279A1 (OSRAM) | 2020-08-18 | 2022-02-24 | ||
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| WO2022255489A1 (ja) | 2021-06-04 | 2022-12-08 | キリンホールディングス株式会社 | 細胞組成物、細胞組成物の製造方法及び細胞組成物を含む医薬組成物 |
| WO2022259721A1 (ja) | 2021-06-10 | 2022-12-15 | 味の素株式会社 | 間葉系幹細胞の製造方法 |
| CA3222770A1 (en) | 2021-06-15 | 2022-12-22 | Takeda Pharmaceutical Company Limited | Method for producing natural killer cells from pluripotent stem cells |
| WO2023286834A1 (ja) | 2021-07-15 | 2023-01-19 | アステラス製薬株式会社 | 血管内皮増殖因子（ｖｅｇｆ）高発現ペリサイト様細胞 |
| WO2023286832A1 (ja) | 2021-07-15 | 2023-01-19 | アステラス製薬株式会社 | 血管内皮増殖因子（ｖｅｇｆ）高発現ペリサイト様細胞の製造方法 |
| EP4386083A4 (en) | 2021-08-11 | 2025-11-12 | Univ Kyoto | METHOD FOR PRODUCING RENAL INTERSTITIAL PROGENITOR CELLS, ERYTHROPOIETIN-PRODUCING CELLS AND METHOD FOR PRODUCING RENIIN-PRODUCING CELLS |
| CN118265792A (zh) | 2021-11-11 | 2024-06-28 | 希里欧斯株式会社 | 基因修饰多能干细胞、来自其的免疫活性细胞、它们的制造方法和它们的用途 |
| JPWO2023153464A1 (OSRAM) | 2022-02-09 | 2023-08-17 | ||
| WO2023210713A1 (ja) | 2022-04-27 | 2023-11-02 | 国立大学法人京都大学 | 心外膜細胞再生促進剤および心外膜細胞の再生促進方法 |
| US20250376727A1 (en) | 2022-06-10 | 2025-12-11 | Kyoto University | Detection method and detection reagent for undifferentiated pluripotent stem cells |
| WO2024248017A1 (ja) | 2023-05-29 | 2024-12-05 | 国立研究開発法人理化学研究所 | 心筋細胞を成熟させる方法及び成熟した心筋細胞の製造方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| EP1186667B1 (en) | 1999-05-18 | 2007-07-18 | Dnavec Research Inc. | Envelope gene-deficient virus vector of paramyxoviridae |
| US8048999B2 (en) * | 2005-12-13 | 2011-11-01 | Kyoto University | Nuclear reprogramming factor |
| EP2137296A2 (en) * | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| CN101932705A (zh) * | 2007-04-07 | 2010-12-29 | 怀特黑德生物医学研究所 | 体细胞重编程 |
| JP2010528622A (ja) * | 2007-05-30 | 2010-08-26 | ザ ジェネラル ホスピタル コーポレイション | 体細胞から多能性細胞を生成する方法 |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| CA2660123C (en) | 2007-10-31 | 2017-05-09 | Kyoto University | Nuclear reprogramming method |
| JPWO2010027062A1 (ja) | 2008-09-04 | 2012-02-02 | 独立行政法人理化学研究所 | Ｂ細胞由来ｉＰＳ細胞およびその用途 |
| WO2010027094A1 (ja) | 2008-09-08 | 2010-03-11 | 独立行政法人理化学研究所 | NKT細胞由来iPS細胞およびそれ由来のNKT細胞 |
| WO2010098419A1 (en) | 2009-02-27 | 2010-09-02 | Kyoto University | Novel nuclear reprogramming substance |
| CN101613717B (zh) | 2009-04-17 | 2012-01-11 | 中国科学院广州生物医药与健康研究院 | 用猪成纤维细胞生成诱导的多能性干细胞的方法 |
| CA2770412C (en) | 2009-08-07 | 2018-09-11 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| CA2789749C (en) | 2010-02-16 | 2018-09-04 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
-
2010
- 2010-02-19 WO PCT/JP2010/053024 patent/WO2010098419A1/en not_active Ceased
- 2010-02-19 CN CN201080011401.7A patent/CN102388136B/zh active Active
- 2010-02-19 JP JP2011536662A patent/JP5553289B2/ja active Active
- 2010-02-19 EP EP13158495.5A patent/EP2607476B1/en active Active
- 2010-02-19 SG SG2011061959A patent/SG173876A1/en unknown
- 2010-02-19 EP EP10746298A patent/EP2401372A4/en not_active Withdrawn
- 2010-02-19 CA CA2753845A patent/CA2753845C/en active Active
- 2010-02-19 US US13/203,735 patent/US8951801B2/en active Active
- 2010-02-19 KR KR1020117022584A patent/KR101764100B1/ko active Active
-
2011
- 2011-08-25 IL IL214833A patent/IL214833A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2753845A1 (en) | 2010-09-02 |
| IL214833A0 (en) | 2011-11-30 |
| CN102388136A (zh) | 2012-03-21 |
| JP2012518988A (ja) | 2012-08-23 |
| SG173876A1 (en) | 2011-09-29 |
| KR20120003867A (ko) | 2012-01-11 |
| EP2607476A1 (en) | 2013-06-26 |
| CA2753845C (en) | 2019-10-29 |
| WO2010098419A1 (en) | 2010-09-02 |
| EP2607476B1 (en) | 2015-04-08 |
| EP2401372A1 (en) | 2012-01-04 |
| CN102388136B (zh) | 2014-10-01 |
| US8951801B2 (en) | 2015-02-10 |
| US20120052583A1 (en) | 2012-03-01 |
| KR101764100B1 (ko) | 2017-08-02 |
| EP2401372A4 (en) | 2012-09-19 |
| JP5553289B2 (ja) | 2014-07-16 |
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Legal Events
| Date | Code | Title | Description |
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| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |