IL192545A - Use of 2mg / cm2 / min dispersed citrate iron to make a drug for the treatment of soft tissue calcification and pharmaceutical preparations containing this citrate iron - Google Patents
Use of 2mg / cm2 / min dispersed citrate iron to make a drug for the treatment of soft tissue calcification and pharmaceutical preparations containing this citrate ironInfo
- Publication number
- IL192545A IL192545A IL192545A IL19254508A IL192545A IL 192545 A IL192545 A IL 192545A IL 192545 A IL192545 A IL 192545A IL 19254508 A IL19254508 A IL 19254508A IL 192545 A IL192545 A IL 192545A
- Authority
- IL
- Israel
- Prior art keywords
- ferric citrate
- medicament
- manufacture
- approximately
- pharmaceutical compositions
- Prior art date
Links
- 229960002413 ferric citrate Drugs 0.000 title 2
- NPFOYSMITVOQOS-UHFFFAOYSA-K iron(III) citrate Chemical compound [Fe+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NPFOYSMITVOQOS-UHFFFAOYSA-K 0.000 title 2
- 238000004090 dissolution Methods 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002037 soft tissue calcification Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76325306P | 2006-01-30 | 2006-01-30 | |
| PCT/US2006/032385 WO2007022435A2 (en) | 2005-08-18 | 2006-08-18 | Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same |
| PCT/US2007/002157 WO2007089577A2 (en) | 2006-01-30 | 2007-01-26 | Method of reversing, preventing, delaying or stabilizing soft tissue calcification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL192545A0 IL192545A0 (en) | 2009-08-03 |
| IL192545A true IL192545A (en) | 2015-08-31 |
Family
ID=39739742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL192545A IL192545A (en) | 2006-01-30 | 2008-06-30 | Use of 2mg / cm2 / min dispersed citrate iron to make a drug for the treatment of soft tissue calcification and pharmaceutical preparations containing this citrate iron |
| IL193099A IL193099A (en) | 2006-01-30 | 2008-07-28 | Use of ferric citrate-containing preparations in the preparation of chronic kidney disease drugs |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL193099A IL193099A (en) | 2006-01-30 | 2008-07-28 | Use of ferric citrate-containing preparations in the preparation of chronic kidney disease drugs |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US20090186939A1 (enExample) |
| EP (3) | EP1978808B1 (enExample) |
| JP (14) | JP2009525276A (enExample) |
| CN (4) | CN105055446B (enExample) |
| AU (2) | AU2007210090B2 (enExample) |
| CA (2) | CA2640974C (enExample) |
| DK (1) | DK1978807T3 (enExample) |
| ES (2) | ES2580127T3 (enExample) |
| HU (1) | HUE028029T2 (enExample) |
| IL (2) | IL192545A (enExample) |
| WO (2) | WO2007089577A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9328133B2 (en) | 2003-02-19 | 2016-05-03 | Panion & Bf Biotech Inc. | Ferric organic compounds, uses thereof and methods of making same |
| US9387191B2 (en) | 2009-07-21 | 2016-07-12 | Keryx Biopharmaceuticals, Inc. | Ferric citrate dosage forms |
| US9750715B2 (en) | 2006-01-30 | 2017-09-05 | Panion & Biotech Inc. | Method of reversing, preventing, delaying or stabilizing soft tissue calcification |
| US9757416B2 (en) | 2003-02-19 | 2017-09-12 | Panion & Bf Biotech Inc. | Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220144872A1 (en) * | 2003-02-19 | 2022-05-12 | Panion & Bf Biotech Inc. | Pharmaceutical-Grade Ferric Organic Compounds, Uses Thereof and Methods of Making Same |
| US7658952B2 (en) | 2007-10-11 | 2010-02-09 | Baxter International Inc. | Dialysis solutions containing pyrophosphates |
| CN102164596A (zh) | 2008-10-27 | 2011-08-24 | Sbi5-Ala生物技术股份有限公司 | 以5-氨基乙酰丙酸或其衍生物、或它们的盐作为有效成分的成人病的预防、改善剂 |
| US8178709B2 (en) * | 2009-07-21 | 2012-05-15 | Biolink Life Sciences, Inc. | Iron preparation suitable for pharmaceutical formulation and process for the preparation thereof |
| EP2594277A4 (en) * | 2010-07-07 | 2014-01-01 | Japan Tobacco Inc | TABLET WITH IRON CITRATE |
| JP2012112785A (ja) * | 2010-11-24 | 2012-06-14 | Tohoku Univ | 透析膜の評価方法 |
| WO2012099139A1 (ja) * | 2011-01-18 | 2012-07-26 | 日本たばこ産業株式会社 | β酸化水酸化鉄を実質的に含まないクエン酸第二鉄 |
| PL3730136T3 (pl) * | 2012-06-21 | 2024-03-25 | Keryx Biopharmaceuticals, Inc. | Zastosowanie cytrynianu żelaza(iii) w leczeniu pacjentów z przewlekłą chorobą nerek |
| JP6348495B2 (ja) * | 2012-09-04 | 2018-06-27 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | シトレートに富むカルシウム・マグネシウム補助剤およびその使用 |
| AU2014341975A1 (en) * | 2013-11-04 | 2016-05-19 | Keryx Biopharmaceuticals, Inc. | Ferric citrate for reducing cardiac failure in chronic kidney disease patients |
| US10172882B2 (en) | 2014-06-22 | 2019-01-08 | Dexcel Pharma Technologies Ltd. | Pharmaceutical compositions comprising ferric citrate and methods for the production thereof |
| US20180222836A1 (en) * | 2015-08-05 | 2018-08-09 | Lupin Limited | Process for the Preparation of Pharmaceutical Grade Ferric Citrate |
| WO2018193648A1 (ja) * | 2017-04-18 | 2018-10-25 | 国立大学法人東北大学 | アルカリ性化剤による血液浄化 |
| JP7578234B2 (ja) * | 2017-04-18 | 2024-11-06 | 国立大学法人東北大学 | アルカリ性化剤による血液浄化 |
| JP7219898B2 (ja) * | 2017-04-18 | 2023-02-09 | 国立大学法人東北大学 | アルカリ性化剤による血液浄化 |
| IT201700085412A1 (it) * | 2017-07-26 | 2019-01-26 | Pharmanutra S P A | Composizione per uso nella prevenzione e nel trattamento di patologie dell'apparato cardiovascolare |
| IT201700089258A1 (it) | 2017-08-02 | 2019-02-02 | Pharmanutra S P A | Composizione per uso nella prevenzione e nel trattamento di carenza di ferro |
| KR102825650B1 (ko) | 2018-01-12 | 2025-06-26 | 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 | 체액 중의 암모니아 및 암모늄의 검출 및 정량화를 위한 시스템 및 방법 |
| US20210267959A1 (en) * | 2018-07-17 | 2021-09-02 | The Regents Of The University Of California | Methods of treating renal disease |
| EP3868371A4 (en) | 2018-10-17 | 2022-11-02 | Tohoku University | Novel pharmaceutical composition |
| KR20210076008A (ko) * | 2018-10-17 | 2021-06-23 | 교토후고리츠다이가쿠호진 | 당뇨병 신증에 있어서의 신장 섬유화 억제제 |
| CA3137691A1 (en) * | 2019-04-28 | 2020-11-05 | Tohoku University | Novel pharmaceutical composition |
| IT201900007311A1 (it) | 2019-05-27 | 2020-11-27 | Alesco Srl | Procedimento per la preparazione di una composizione comprendente acidi grassi cetilati |
| IT201900007326A1 (it) | 2019-05-27 | 2020-11-27 | Alesco Srl | Composizioni comprendenti acidi grassi cetilati e loro uso nel trattamento di artriti e stati infiammatori articolari |
| JP2024507417A (ja) * | 2021-02-24 | 2024-02-19 | モクシーテック リミテッド ライアビリティ カンパニー | イヌパルボウイルス感染を治療するための組成物および方法 |
| CN117999069A (zh) | 2021-05-27 | 2024-05-07 | 凯克斯生物制药公司 | 柠檬酸铁的儿科调配物 |
| KR102623739B1 (ko) * | 2022-07-28 | 2024-01-11 | 주식회사 페라메드 | 시트르산과 철을 포함하는 착화합물 및 그를 포함하는 식품 조성물 |
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| KR20080037083A (ko) | 2005-08-18 | 2008-04-29 | 글로보아시아 엘엘씨 | 약학용 등급의 유기 철 화합물, 그 용도 및 이의 제조 방법 |
| JP4692234B2 (ja) | 2005-11-10 | 2011-06-01 | ソニー株式会社 | 変調テーブル、変調装置および方法、プログラム、並びに記録媒体 |
| US7682811B2 (en) | 2006-01-27 | 2010-03-23 | University Of Massachusetts | Systems and methods for producing biofuels and related materials |
| CN105055446B (zh) | 2006-01-30 | 2022-06-03 | 宝龄富锦生技股份有限公司 | 逆转、防止、延迟或稳定软组织钙化的方法 |
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| JP5526466B2 (ja) | 2007-07-17 | 2014-06-18 | 株式会社大林組 | 耐火セグメントの製造方法 |
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| KR20140016438A (ko) | 2009-07-21 | 2014-02-07 | 케릭스 바이오파마슈티컬스 인코포레이티드 | 구연산철 투여형태 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9328133B2 (en) | 2003-02-19 | 2016-05-03 | Panion & Bf Biotech Inc. | Ferric organic compounds, uses thereof and methods of making same |
| US9757416B2 (en) | 2003-02-19 | 2017-09-12 | Panion & Bf Biotech Inc. | Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same |
| US9750715B2 (en) | 2006-01-30 | 2017-09-05 | Panion & Biotech Inc. | Method of reversing, preventing, delaying or stabilizing soft tissue calcification |
| US9387191B2 (en) | 2009-07-21 | 2016-07-12 | Keryx Biopharmaceuticals, Inc. | Ferric citrate dosage forms |
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