IL183634A - Polymer-von willebrand factor-conjugates - Google Patents

Polymer-von willebrand factor-conjugates

Info

Publication number
IL183634A
IL183634A IL183634A IL18363407A IL183634A IL 183634 A IL183634 A IL 183634A IL 183634 A IL183634 A IL 183634A IL 18363407 A IL18363407 A IL 18363407A IL 183634 A IL183634 A IL 183634A
Authority
IL
Israel
Prior art keywords
molecule
vwf
life
vivo half
proteinaceous
Prior art date
Application number
IL183634A
Other languages
English (en)
Other versions
IL183634A0 (en
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of IL183634A0 publication Critical patent/IL183634A0/en
Publication of IL183634A publication Critical patent/IL183634A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL183634A 2004-12-27 2007-06-04 Polymer-von willebrand factor-conjugates IL183634A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US63924404P 2004-12-27 2004-12-27
US66837805P 2005-04-04 2005-04-04
US67190105P 2005-04-15 2005-04-15
US68508605P 2005-05-26 2005-05-26
PCT/US2005/046879 WO2006071801A2 (en) 2004-12-27 2005-12-23 Polymer-von willebrand factor-conjugates

Publications (2)

Publication Number Publication Date
IL183634A0 IL183634A0 (en) 2007-09-20
IL183634A true IL183634A (en) 2012-02-29

Family

ID=36540284

Family Applications (1)

Application Number Title Priority Date Filing Date
IL183634A IL183634A (en) 2004-12-27 2007-06-04 Polymer-von willebrand factor-conjugates

Country Status (15)

Country Link
US (4) US7884075B2 (cg-RX-API-DMAC7.html)
EP (1) EP1835938B1 (cg-RX-API-DMAC7.html)
JP (2) JP5022231B2 (cg-RX-API-DMAC7.html)
KR (1) KR20070092754A (cg-RX-API-DMAC7.html)
CN (1) CN101163506B (cg-RX-API-DMAC7.html)
AU (1) AU2005322067B8 (cg-RX-API-DMAC7.html)
BR (1) BRPI0519562A2 (cg-RX-API-DMAC7.html)
CA (1) CA2591852A1 (cg-RX-API-DMAC7.html)
DK (1) DK1835938T3 (cg-RX-API-DMAC7.html)
ES (1) ES2434035T3 (cg-RX-API-DMAC7.html)
IL (1) IL183634A (cg-RX-API-DMAC7.html)
MX (1) MX2007007877A (cg-RX-API-DMAC7.html)
PL (1) PL1835938T3 (cg-RX-API-DMAC7.html)
PT (1) PT1835938E (cg-RX-API-DMAC7.html)
WO (1) WO2006071801A2 (cg-RX-API-DMAC7.html)

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US8357779B2 (en) 2013-01-22
CN101163506B (zh) 2012-09-26
HK1105276A1 (en) 2008-02-06
WO2006071801A2 (en) 2006-07-06
CA2591852A1 (en) 2006-07-06
AU2005322067B8 (en) 2012-07-26
US8835388B2 (en) 2014-09-16
US20130190242A1 (en) 2013-07-25
US20120135462A1 (en) 2012-05-31
IL183634A0 (en) 2007-09-20
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AU2005322067B2 (en) 2012-07-05
CN101163506A (zh) 2008-04-16
JP2008525491A (ja) 2008-07-17
PT1835938E (pt) 2013-11-06
US20110111455A1 (en) 2011-05-12
AU2005322067A1 (en) 2006-07-06
US20060160948A1 (en) 2006-07-20
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EP1835938A2 (en) 2007-09-26
US7884075B2 (en) 2011-02-08
BRPI0519562A2 (pt) 2009-01-27
ES2434035T3 (es) 2013-12-13
DK1835938T3 (da) 2013-11-04
WO2006071801A3 (en) 2007-08-16
PL1835938T3 (pl) 2014-01-31
JP2012126750A (ja) 2012-07-05

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