IL166054A0 - Novel compounds pharmaceutical compositions containing same and methods of use for same - Google Patents

Novel compounds pharmaceutical compositions containing same and methods of use for same

Info

Publication number
IL166054A0
IL166054A0 IL16605403A IL16605403A IL166054A0 IL 166054 A0 IL166054 A0 IL 166054A0 IL 16605403 A IL16605403 A IL 16605403A IL 16605403 A IL16605403 A IL 16605403A IL 166054 A0 IL166054 A0 IL 166054A0
Authority
IL
Israel
Prior art keywords
same
methods
pharmaceutical compositions
compositions containing
novel compounds
Prior art date
Application number
IL16605403A
Other languages
English (en)
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of IL166054A0 publication Critical patent/IL166054A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
IL16605403A 2002-07-01 2003-07-01 Novel compounds pharmaceutical compositions containing same and methods of use for same IL166054A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39280902P 2002-07-01 2002-07-01
PCT/US2003/020960 WO2004006835A2 (en) 2002-07-01 2003-07-01 Novel compounds, pharmaceutical compositions containing same, and methods of use for same

Publications (1)

Publication Number Publication Date
IL166054A0 true IL166054A0 (en) 2006-01-15

Family

ID=30115535

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16605403A IL166054A0 (en) 2002-07-01 2003-07-01 Novel compounds pharmaceutical compositions containing same and methods of use for same

Country Status (15)

Country Link
US (1) US20060241177A1 (zh)
EP (1) EP1534263A4 (zh)
JP (1) JP2005533107A (zh)
KR (1) KR20050072670A (zh)
CN (2) CN100482219C (zh)
AU (1) AU2003248810B2 (zh)
BR (1) BRPI0312413A2 (zh)
CA (1) CA2491183A1 (zh)
EA (1) EA010484B1 (zh)
HK (1) HK1086485A1 (zh)
IL (1) IL166054A0 (zh)
MX (1) MXPA05000152A (zh)
SG (1) SG170620A1 (zh)
WO (1) WO2004006835A2 (zh)
ZA (1) ZA200500203B (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9018737D0 (en) * 1990-08-28 1990-10-10 Goodfellow John W Phosphetic patellar components
BR0307421A (pt) 2002-02-08 2004-12-28 Johns Kophkins University Scho Estimulação do cpt-1 como um freio para reduzir peso
SG149701A1 (en) * 2002-07-09 2009-02-27 Fasgen Llc Methods of treating microbial infections in humans and animals
CN101007796A (zh) * 2006-01-27 2007-08-01 北京摩力克科技有限公司 新型五元杂环化合物及其制备方法和医疗用途
CN101190904A (zh) * 2006-11-23 2008-06-04 中国人民解放军军事医学科学院毒物药物研究所 脂肪酸合成酶抑制剂及其制药用途
CN101820757A (zh) 2007-06-01 2010-09-01 普林斯顿大学托管委员会 通过调节宿主细胞代谢途径治疗病毒感染
WO2010118324A2 (en) 2009-04-09 2010-10-14 Nuclea Biotechnologies, LLC Antibodies against fatty acid synthase
FR2957078B1 (fr) * 2010-03-05 2012-05-04 Centre Nat Rech Scient Acides paraconiques comme activateurs de pigmentation
US8450350B2 (en) 2010-05-05 2013-05-28 Infinity Pharmaceuticals, Inc. Triazoles as inhibitors of fatty acid synthase
EP3159331A1 (en) 2010-05-05 2017-04-26 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
US20150099730A1 (en) * 2012-09-07 2015-04-09 Janssen Pharmaceutica, Nv Imidazolin-5-one derivative useful as fasn inhibitors for the treatment of cancer
CN103145662B (zh) * 2013-02-18 2014-07-16 深圳万和制药有限公司 N-取代的氨基丁内酯衍生物及其用途
CN103864731B (zh) * 2014-02-19 2016-01-20 成都中医药大学 含季碳手性中心的呋喃内酯环类化合物的合成方法
CN104530018B (zh) * 2014-12-12 2017-04-12 郑州大学 含α‑亚甲基‑γ‑丁内酯结构的吲哚类化合物、制备方法及其应用
AU2016215228A1 (en) * 2015-02-05 2017-08-10 Dermira Inc. Synthetic process for preparing 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate
KR102038971B1 (ko) * 2018-03-12 2019-11-26 주식회사 엔지켐생명과학 디아실글리세롤락톤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역증진제
KR20220159831A (ko) 2021-05-26 2022-12-05 울산과학기술원 미토콘드리아 표적화 뉴클레오펩티드 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496187A (en) * 1967-03-20 1970-02-17 American Home Prod N-(heterocyclyl)aconamides
US3472878A (en) * 1969-01-27 1969-10-14 American Home Prod N-(hydroxyaryl)aconamides
US4753871A (en) * 1986-12-12 1988-06-28 Eastman Kodak Company Cyan dye-forming couplers and photographic materials containing same
JPS63169848A (ja) * 1987-01-07 1988-07-13 Nec Corp デジタルデ−タ通信におけるデ−タ端末収容方式
JP2524760B2 (ja) * 1987-07-10 1996-08-14 テイカ株式会社 新規抗生物質
JPH04199148A (ja) * 1990-11-29 1992-07-20 Konica Corp ハロゲン化銀写真感光材料
JPH05246822A (ja) * 1992-03-07 1993-09-24 Nippon Paint Co Ltd 抗菌剤
JPH07112931A (ja) * 1993-08-27 1995-05-02 Nippon Paint Co Ltd エプスタイン−バーウイルス活性化抑制剤
ES2251002T3 (es) * 1995-11-17 2006-04-16 The Johns Hopkins University Inhibicion de sintasa de acido graso, como medio para reducir la masa adipocita.
KR20090031957A (ko) * 1999-11-12 2009-03-30 더 존스 홉킨스 유니버시티 세포내 말로닐 CoA의 수준을 증가시킴에 의한 암의 치료방법
JP2003528051A (ja) * 2000-02-16 2003-09-24 ザ ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン ニューロペプチドyレベルの減少によって誘導される体重減少

Also Published As

Publication number Publication date
SG170620A1 (en) 2011-05-30
HK1086485A1 (en) 2006-09-22
EA010484B1 (ru) 2008-10-30
KR20050072670A (ko) 2005-07-12
CA2491183A1 (en) 2004-01-22
CN1705478A (zh) 2005-12-07
EP1534263A2 (en) 2005-06-01
AU2003248810A1 (en) 2004-02-02
EA200500122A1 (ru) 2005-12-29
JP2005533107A (ja) 2005-11-04
EP1534263A4 (en) 2006-10-11
ZA200500203B (en) 2009-09-30
US20060241177A1 (en) 2006-10-26
WO2004006835A2 (en) 2004-01-22
AU2003248810B2 (en) 2009-08-20
BRPI0312413A2 (pt) 2016-08-02
CN100482219C (zh) 2009-04-29
CN101633650A (zh) 2010-01-27
WO2004006835A3 (en) 2004-07-22
MXPA05000152A (es) 2005-10-24

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