PL1664050T3 - Neuroprotekcyjne związki bicykliczne i zawierające je kompozycje farmaceutyczne - Google Patents
Neuroprotekcyjne związki bicykliczne i zawierające je kompozycje farmaceutyczneInfo
- Publication number
- PL1664050T3 PL1664050T3 PL04782733T PL04782733T PL1664050T3 PL 1664050 T3 PL1664050 T3 PL 1664050T3 PL 04782733 T PL04782733 T PL 04782733T PL 04782733 T PL04782733 T PL 04782733T PL 1664050 T3 PL1664050 T3 PL 1664050T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- bicyclic compounds
- neuroprotective
- neuroprotective bicyclic
- Prior art date
Links
- 125000002619 bicyclic group Chemical group 0.000 title 1
- 230000000324 neuroprotective effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49995603P | 2003-09-03 | 2003-09-03 | |
| EP04782733.2A EP1664050B1 (en) | 2003-09-03 | 2004-08-31 | Neuroprotective bicyclic compounds and pharmaceutical compositions containing them |
| PCT/US2004/028308 WO2005023815A2 (en) | 2003-09-03 | 2004-08-31 | Neuroprotective bicyclic compounds and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1664050T3 true PL1664050T3 (pl) | 2016-08-31 |
Family
ID=34272894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04782733T PL1664050T3 (pl) | 2003-09-03 | 2004-08-31 | Neuroprotekcyjne związki bicykliczne i zawierające je kompozycje farmaceutyczne |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8067425B2 (pl) |
| EP (1) | EP1664050B1 (pl) |
| JP (1) | JP4842817B2 (pl) |
| DK (1) | DK1664050T3 (pl) |
| ES (1) | ES2564803T3 (pl) |
| HU (1) | HUE028528T2 (pl) |
| PL (1) | PL1664050T3 (pl) |
| SI (1) | SI1664050T1 (pl) |
| WO (1) | WO2005023815A2 (pl) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100553636C (zh) | 2000-08-04 | 2009-10-28 | Dmi生物科学公司 | 二酮基哌嗪和包含它们的组合物的使用方法 |
| JP2006523213A (ja) * | 2003-03-20 | 2006-10-12 | ニューレン ファーマシューティカルズ リミテッド | 神経保護大環状化合物及びそれらの使用方法 |
| KR20120091266A (ko) * | 2003-05-15 | 2012-08-17 | 디엠아이 바이오사이언시스, 인크 | Ｔ-세포 매개성 질환의 치료 방법 |
| WO2008063311A2 (en) * | 2006-10-11 | 2008-05-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
| US8519127B2 (en) * | 2003-09-03 | 2013-08-27 | Mike John Bickerdike | Cyclic glycyl-2-allyl proline and its use in treatment of peripheral neuropathy |
| US8791117B2 (en) * | 2003-09-03 | 2014-07-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| US9891219B2 (en) * | 2008-10-10 | 2018-02-13 | Mayo Foundation For Medical Education And Research | Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive |
| US7928233B2 (en) * | 2009-02-10 | 2011-04-19 | Hoffmann-La Roche Inc. | Spiroindolinone pyridine derivatives |
| WO2012033792A2 (en) | 2010-09-07 | 2012-03-15 | Dmi Acquisition Corp. | Treatment of diseases |
| MX362164B (es) | 2011-10-10 | 2019-01-07 | Ampio Pharmaceuticals Inc | Tratamiento de enfermedad de articulacion degenerativa. |
| BR112014007657A2 (pt) | 2011-10-10 | 2017-04-11 | Ampio Pharmaceuticals Inc | dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação |
| SG11201400283RA (en) | 2011-10-28 | 2014-03-28 | Ampio Pharmaceuticals Inc | Treatment of rhinitis |
| CA2900335C (en) * | 2012-10-22 | 2021-10-26 | City Of Hope | Synthetic analogs of epipolythiodioxopiperazines and uses thereof |
| SG10201707619RA (en) | 2013-03-15 | 2017-10-30 | Ampio Pharmaceuticals Inc | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| LT3024463T (lt) | 2013-07-25 | 2020-07-10 | Neuren Pharmaceuticals Limited | Neuroapsauginiai bicikliniai junginiai ir jų panaudojimo būdai autizmo spektro sutrikimų ir neuroliginių vystymosi sutrikimų gydymui |
| EP3183240A4 (en) | 2014-08-18 | 2018-06-27 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| HK1246669A1 (zh) | 2015-06-22 | 2018-09-14 | Ampio Pharmaceuticals, Inc. | 人血清白蛋白低分子量组分在疾病治疗中的应用 |
| JP7381000B2 (ja) | 2016-05-26 | 2023-11-15 | 株式会社アミノアップ | 睡眠改善剤 |
| CN109952104B (zh) | 2016-09-15 | 2023-03-28 | 希望之城 | 二硫etp衍生物 |
| JP7321534B2 (ja) * | 2018-03-16 | 2023-08-07 | 脳科学香料株式会社 | 低酸素障害、虚血再灌流障害又は炎症の予防又は治療剤、移植用細胞保護剤、及び生体保存剤 |
| JP7699378B2 (ja) * | 2018-05-15 | 2025-06-27 | ハン ロイ トラン ロイド | 軽度の認知障害、抑うつ、および精神障害の治療のための治療薬組成物およびその使用方法 |
| CN115243688A (zh) | 2019-10-22 | 2022-10-25 | 诺仁制药有限公司 | 双环化合物和它们在治疗pitt hopkins综合征中的使用方法 |
| GEAP202316350A (en) * | 2021-02-12 | 2023-10-25 | Neuren Pharmaceuticals Ltd | Treatments of prader-willi syndrome |
| BE1032058B1 (nl) * | 2023-10-26 | 2025-10-02 | Rousselot Bv | Cyclische analoog van glycine-proline voor gebruik bij de preventie en/of behandeling van fibrose |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH469006A (de) * | 1965-07-07 | 1969-02-28 | Sandoz Ag | Verfahren zur Herstellung neuer synthetischer Alkaloide |
| EP0626174A3 (en) * | 1993-04-21 | 1996-01-03 | Takeda Chemical Industries Ltd | Method and composition for the prophylaxis and / or treatment of underactive organs. |
| US7202279B1 (en) * | 1998-02-11 | 2007-04-10 | Georgetown University | Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders |
| AU2002340465A1 (en) * | 2001-11-09 | 2003-05-19 | Neuronz Biosciences, Inc. | Cyclo(prolyl-glycine) and methods of use to treat neural disorders |
| WO2003041655A2 (en) * | 2001-11-13 | 2003-05-22 | Loi Tran | Therapeutic agent composition and method of use |
| US7232798B2 (en) * | 2001-11-13 | 2007-06-19 | Tran Loi H | Neuroprotection and neuroegenisis by administering cyclic prolyl glycine |
| JP2006523213A (ja) | 2003-03-20 | 2006-10-12 | ニューレン ファーマシューティカルズ リミテッド | 神経保護大環状化合物及びそれらの使用方法 |
-
2004
- 2004-08-31 DK DK04782733.2T patent/DK1664050T3/en active
- 2004-08-31 WO PCT/US2004/028308 patent/WO2005023815A2/en not_active Ceased
- 2004-08-31 SI SI200432303T patent/SI1664050T1/sl unknown
- 2004-08-31 PL PL04782733T patent/PL1664050T3/pl unknown
- 2004-08-31 US US10/570,395 patent/US8067425B2/en not_active Expired - Lifetime
- 2004-08-31 JP JP2006525396A patent/JP4842817B2/ja not_active Expired - Lifetime
- 2004-08-31 HU HUE04782733A patent/HUE028528T2/en unknown
- 2004-08-31 ES ES04782733.2T patent/ES2564803T3/es not_active Expired - Lifetime
- 2004-08-31 EP EP04782733.2A patent/EP1664050B1/en not_active Expired - Lifetime
-
2006
- 2006-04-07 US US11/399,974 patent/US7776876B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4842817B2 (ja) | 2011-12-21 |
| US8067425B2 (en) | 2011-11-29 |
| EP1664050A2 (en) | 2006-06-07 |
| JP2007504235A (ja) | 2007-03-01 |
| HUE028528T2 (en) | 2016-12-28 |
| DK1664050T3 (en) | 2016-03-07 |
| ES2564803T3 (es) | 2016-03-29 |
| WO2005023815A3 (en) | 2005-07-21 |
| US20060258663A1 (en) | 2006-11-16 |
| US7776876B2 (en) | 2010-08-17 |
| SI1664050T1 (sl) | 2016-04-29 |
| EP1664050B1 (en) | 2015-12-09 |
| US20070197511A1 (en) | 2007-08-23 |
| WO2005023815A2 (en) | 2005-03-17 |
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