IL158139A0 - Stabilized formulations of phosphatidyl serine - Google Patents

Stabilized formulations of phosphatidyl serine

Info

Publication number
IL158139A0
IL158139A0 IL15813903A IL15813903A IL158139A0 IL 158139 A0 IL158139 A0 IL 158139A0 IL 15813903 A IL15813903 A IL 15813903A IL 15813903 A IL15813903 A IL 15813903A IL 158139 A0 IL158139 A0 IL 158139A0
Authority
IL
Israel
Prior art keywords
phosphatidyl serine
stabilized formulations
formulations
stabilized
phosphatidyl
Prior art date
Application number
IL15813903A
Other languages
English (en)
Original Assignee
Enzymotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enzymotec Ltd filed Critical Enzymotec Ltd
Priority to IL15813903A priority Critical patent/IL158139A0/xx
Priority to CNA2004800348781A priority patent/CN1897919A/zh
Priority to US10/572,782 priority patent/US8324187B2/en
Priority to KR1020127005527A priority patent/KR20120039752A/ko
Priority to BRPI0414721-9A priority patent/BRPI0414721A/pt
Priority to JP2006527572A priority patent/JP5077841B2/ja
Priority to AU2004273700A priority patent/AU2004273700C1/en
Priority to HK06113400.1A priority patent/HK1092703B/en
Priority to PCT/IL2004/000895 priority patent/WO2005027822A2/en
Priority to KR1020067005677A priority patent/KR101226787B1/ko
Priority to EP04770566A priority patent/EP1663157B1/en
Priority to CN201110043969.3A priority patent/CN102160651B/zh
Priority to CA2540170A priority patent/CA2540170C/en
Priority to ES04770566T priority patent/ES2399049T3/es
Publication of IL158139A0 publication Critical patent/IL158139A0/xx
Priority to IL174420A priority patent/IL174420A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
IL15813903A 2003-09-25 2003-09-25 Stabilized formulations of phosphatidyl serine IL158139A0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IL15813903A IL158139A0 (en) 2003-09-25 2003-09-25 Stabilized formulations of phosphatidyl serine
HK06113400.1A HK1092703B (en) 2003-09-25 2004-09-26 Stabilized formulations of phosphatidylserine
PCT/IL2004/000895 WO2005027822A2 (en) 2003-09-25 2004-09-26 Stabilized formulations of phosphatidylserine
KR1020127005527A KR20120039752A (ko) 2003-09-25 2004-09-26 포스파티딜세린의 안정화된 제제
BRPI0414721-9A BRPI0414721A (pt) 2003-09-25 2004-09-26 formulações estabilizadas de fosfatidilserina
JP2006527572A JP5077841B2 (ja) 2003-09-25 2004-09-26 ホスファチジルセリンの安定化された配合物
AU2004273700A AU2004273700C1 (en) 2003-09-25 2004-09-26 Stabilized formulations of phosphatidylserine
CNA2004800348781A CN1897919A (zh) 2003-09-25 2004-09-26 稳定的磷脂酰丝氨酸制剂
US10/572,782 US8324187B2 (en) 2003-09-25 2004-09-26 Stabilized formulations of phosphatidylserine
KR1020067005677A KR101226787B1 (ko) 2003-09-25 2004-09-26 포스파티딜세린의 안정화된 제제
EP04770566A EP1663157B1 (en) 2003-09-25 2004-09-26 Stabilized formulations of phosphatidylserine
CN201110043969.3A CN102160651B (zh) 2003-09-25 2004-09-26 稳定的磷脂酰丝氨酸制剂
CA2540170A CA2540170C (en) 2003-09-25 2004-09-26 Stabilized formulations of phosphatidylserine
ES04770566T ES2399049T3 (es) 2003-09-25 2004-09-26 Formulaciones estabilizadas de fosfatidilserina
IL174420A IL174420A (en) 2003-09-25 2006-03-20 Phosphatidylsarin preparations are stabilized

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15813903A IL158139A0 (en) 2003-09-25 2003-09-25 Stabilized formulations of phosphatidyl serine

Publications (1)

Publication Number Publication Date
IL158139A0 true IL158139A0 (en) 2004-09-27

Family

ID=34073789

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15813903A IL158139A0 (en) 2003-09-25 2003-09-25 Stabilized formulations of phosphatidyl serine
IL174420A IL174420A (en) 2003-09-25 2006-03-20 Phosphatidylsarin preparations are stabilized

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL174420A IL174420A (en) 2003-09-25 2006-03-20 Phosphatidylsarin preparations are stabilized

Country Status (11)

Country Link
US (1) US8324187B2 (enExample)
EP (1) EP1663157B1 (enExample)
JP (1) JP5077841B2 (enExample)
KR (2) KR101226787B1 (enExample)
CN (1) CN1897919A (enExample)
AU (1) AU2004273700C1 (enExample)
BR (1) BRPI0414721A (enExample)
CA (1) CA2540170C (enExample)
ES (1) ES2399049T3 (enExample)
IL (2) IL158139A0 (enExample)
WO (1) WO2005027822A2 (enExample)

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US7935365B2 (en) * 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
US20050130937A1 (en) 2003-10-22 2005-06-16 Enzymotec Ltd. Lipids containing omega-3 and omega-6 fatty acids
US8052992B2 (en) * 2003-10-22 2011-11-08 Enzymotec Ltd. Glycerophospholipids containing omega-3 and omega-6 fatty acids and their use in the treatment and improvement of cognitive functions
CA2611121C (en) 2005-05-31 2014-01-28 Arla Foods Amba Phosphatidylserine enriched milk fractions for the formulation of functional foods
HUE037129T2 (hu) * 2005-12-15 2018-08-28 Nestec Sa Kompozíciók és eljárások agyi funkció megõrzésére
US8877239B2 (en) * 2010-08-12 2014-11-04 Nutritional Therapeutics, Inc. Lipid supplements for maintaining health and treatment of acute and chronic disorders
DE102007042557A1 (de) 2007-09-07 2009-03-19 Membramed Gmbh Neuartige Formulierung von Phospholipiden
JP5432563B2 (ja) * 2009-03-31 2014-03-05 株式会社ファンケル ホスファチジルセリン含有カプセル及びカプセル充填用ホスファチジルセリン組成物
EP2464350B1 (en) * 2009-09-11 2016-08-24 Nestec S.A. Compositions and methods for enhancing cognitive and related functions in animals
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
WO2012143860A1 (en) * 2011-04-18 2012-10-26 Jian Guan Ameliorating cognitive decline
CN102908336B (zh) * 2011-08-05 2015-10-28 深圳市华正实业有限公司 磷脂酰丝氨酸的稳定制剂、其制备方法、应用和应用产物
ITPD20120021A1 (it) 2012-01-26 2013-07-27 Fidia Farmaceutici "nuove composizioni farmaceutiche contenenti fosfatidilserina e curcumina".
ITMI20121784A1 (it) * 2012-10-22 2014-04-23 Velleja Res Srl Composizioni galattogeniche a base di fosfatidilserina
US9101580B2 (en) * 2012-12-18 2015-08-11 Matthew Bennett Compositions and methods for treating traumatic brain injury
DK2769725T3 (en) * 2013-02-22 2016-08-22 Lipogen Ltd PREPARATIONS FOR USE AT relief of symptoms associated with premenstrual syndrome and premenstrual dysphoric disorder
EP3171706B2 (en) * 2014-07-25 2024-10-16 Frutarom Limited Nutritional compositions containing phosphatidylserine powder
CN104327114A (zh) * 2014-11-06 2015-02-04 江南大学 一种磷脂酰丝氨酸的制备方法
WO2017125816A1 (en) * 2016-01-21 2017-07-27 Enzymotec Ltd. Methods using phosphatidylserine powder
CN110283803B (zh) * 2016-06-02 2021-08-03 天津科技大学 一种磷脂酶d及其制备磷脂酸、磷脂酰丝氨酸的方法
CN107125752B (zh) * 2017-06-14 2020-06-30 安徽省芬格欣生物药业有限公司 一种增进记忆功能的磷脂酰丝氨酸口服液及制备方法
CN107034248A (zh) * 2017-06-19 2017-08-11 成都新柯力化工科技有限公司 一种连续高效酶转化合成食品用磷脂酰丝氨酸的方法
CN107722051B (zh) * 2017-08-24 2020-08-14 南通励成生物工程有限公司 制备磷脂酰丝氨酸盐的方法
GB201821049D0 (en) * 2018-12-21 2019-02-06 Ge Healthcare As Ultrasound contrast agent and methods for use therof
US20220249455A1 (en) * 2019-07-15 2022-08-11 R.P. Scherer Technologies, Llc Enteric proton pump inhibitor softgel capsule
CN110938090A (zh) * 2019-12-24 2020-03-31 南通励成生物工程有限公司 一种磷脂酰丝氨酸的纯化方法
CN112314949A (zh) * 2020-11-04 2021-02-05 上海欧睿生物科技有限公司 一种磷脂酰丝氨酸液体配制方法
KR102754261B1 (ko) * 2022-05-12 2025-01-10 주식회사 한국인삼공사 붕해성이 개선된 포스파티딜세린 함유 연질캡슐
WO2026014835A1 (ko) * 2024-07-12 2026-01-15 주식회사 아스트로젠 L-세린의 리포좀 제형 및 이의 제조 방법

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CN1306736C (zh) 2003-06-13 2007-03-21 松下电器产业株式会社 用于射频光学传输的系统和方法
US20050130937A1 (en) * 2003-10-22 2005-06-16 Enzymotec Ltd. Lipids containing omega-3 and omega-6 fatty acids
US7935365B2 (en) * 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
EP1898722B1 (en) * 2005-04-28 2013-04-10 Enzymotec Ltd. Polar lipid mixtures, their preparation and uses

Also Published As

Publication number Publication date
KR101226787B1 (ko) 2013-01-25
KR20060123100A (ko) 2006-12-01
AU2004273700C1 (en) 2010-03-11
US8324187B2 (en) 2012-12-04
ES2399049T3 (es) 2013-03-25
KR20120039752A (ko) 2012-04-25
EP1663157B1 (en) 2012-11-28
HK1092703A1 (en) 2007-02-16
AU2004273700A1 (en) 2005-03-31
WO2005027822A3 (en) 2005-10-06
JP2007506733A (ja) 2007-03-22
AU2004273700B2 (en) 2009-10-29
JP5077841B2 (ja) 2012-11-21
CA2540170C (en) 2012-02-21
CN102160651A (zh) 2011-08-24
CN1897919A (zh) 2007-01-17
BRPI0414721A (pt) 2006-11-21
US20070160659A1 (en) 2007-07-12
CA2540170A1 (en) 2005-03-31
IL174420A0 (en) 2006-08-01
WO2005027822A2 (en) 2005-03-31
EP1663157A2 (en) 2006-06-07
EP1663157A4 (en) 2010-02-24
IL174420A (en) 2015-02-26

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