PT1576951E - Formulações para administração rectal de agentes com acção trombolitica - Google Patents

Formulações para administração rectal de agentes com acção trombolitica Download PDF

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Publication number
PT1576951E
PT1576951E PT03767381T PT03767381T PT1576951E PT 1576951 E PT1576951 E PT 1576951E PT 03767381 T PT03767381 T PT 03767381T PT 03767381 T PT03767381 T PT 03767381T PT 1576951 E PT1576951 E PT 1576951E
Authority
PT
Portugal
Prior art keywords
thrombolytically
formulations
active agents
rectal administration
rectal
Prior art date
Application number
PT03767381T
Other languages
English (en)
Inventor
Maria Acelia Marrero Miragaya
Ana Aguilera Barreto
Lisette Gonzalez Chavez
Eduardo Martinez Diaz
Beatriz Torrez Cabrera
Carelia Cosme Diaz
Milesa Y Josefina Sarmie Mayea
Luciano Francisco Hern Marrero
Beatriz Tamargo Santos
Original Assignee
Ct Ingenieria Genetica Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Ingenieria Genetica Biotech filed Critical Ct Ingenieria Genetica Biotech
Publication of PT1576951E publication Critical patent/PT1576951E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT03767381T 2002-12-27 2003-12-22 Formulações para administração rectal de agentes com acção trombolitica PT1576951E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20020336A CU23203A1 (es) 2002-12-27 2002-12-27 Formulaciones que contienen agentes de accion trombolitica para su administracion por via rectal

Publications (1)

Publication Number Publication Date
PT1576951E true PT1576951E (pt) 2009-01-09

Family

ID=40091670

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03767381T PT1576951E (pt) 2002-12-27 2003-12-22 Formulações para administração rectal de agentes com acção trombolitica

Country Status (19)

Country Link
US (1) US10213379B2 (pt)
EP (1) EP1576951B1 (pt)
JP (1) JP2006512374A (pt)
KR (1) KR100804013B1 (pt)
CN (1) CN100335128C (pt)
AR (1) AR042646A1 (pt)
AT (1) ATE409460T1 (pt)
AU (1) AU2003291916B2 (pt)
BR (1) BRPI0317780B8 (pt)
CA (1) CA2527572C (pt)
CU (1) CU23203A1 (pt)
DE (1) DE60323874D1 (pt)
DK (1) DK1576951T3 (pt)
ES (1) ES2315537T3 (pt)
MX (1) MXPA05007006A (pt)
MY (1) MY142241A (pt)
PT (1) PT1576951E (pt)
WO (1) WO2004058219A1 (pt)
ZA (1) ZA200505399B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660429B (zh) * 2005-01-10 2011-09-07 王振军 基质金属蛋白酶（mmp）抑制剂用于治疗痔的新用途
CN100364610C (zh) * 2005-12-12 2008-01-30 北京大学 提高蚓激酶口服吸收生物利用度的方法
CN102091326B (zh) * 2009-12-15 2013-04-03 上海凯茂生物医药有限公司 治疗因肛门皮下的静脉丛发生扩大或曲张所引发的痔类疾病的经皮给药制剂及制备方法
CN102552916B (zh) * 2010-12-09 2014-04-23 上海凯茂生物医药有限公司 水杨酸钠的新用途
EP3115037B1 (de) * 2015-07-08 2018-08-15 Dr. Falk Pharma Gmbh Pharmazeutische formulierung zur behandlung von entzündlichen veränderungen des enddarms

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3804600A1 (de) * 1988-02-13 1989-08-24 Basf Ag Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz
GB8808810D0 (en) * 1988-04-14 1988-05-18 Biopharm Clinical Research Ltd Heparin-containing formulations
US5098707A (en) * 1989-07-31 1992-03-24 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5885967A (en) * 1994-03-04 1999-03-23 Eli Lilly And Company Antithrombotic agents
US5720962A (en) * 1995-10-04 1998-02-24 Au Pharmaceuticals, Inc. Analgesic lotion for hemorrhoids and method of making such lotion
US5837688A (en) * 1996-11-27 1998-11-17 Gelfand; Mathew I. Use of thrombolytic reagents for prevention of vascular disease
WO1999017784A1 (en) * 1997-10-07 1999-04-15 Regents Of The University Of California Corporation Treating occlusive peripheral vascular disease and coronary disease with combinations of heparin and an adenoside a2 agonist, or with adenosine
AU7965000A (en) * 1999-09-27 2001-04-30 Jun-Suk Oh Use of analgesics as digestive and medicines for expectorating and transdermal therapeutic system using the same

Also Published As

Publication number Publication date
WO2004058219A1 (es) 2004-07-15
ATE409460T1 (de) 2008-10-15
US20070166298A1 (en) 2007-07-19
AU2003291916B2 (en) 2007-03-08
CA2527572A1 (en) 2004-07-15
CN100335128C (zh) 2007-09-05
US10213379B2 (en) 2019-02-26
AU2003291916A1 (en) 2004-07-22
JP2006512374A (ja) 2006-04-13
EP1576951A1 (en) 2005-09-21
CU23203A1 (es) 2007-05-18
AR042646A1 (es) 2005-06-29
BRPI0317780B8 (pt) 2021-05-25
EP1576951B1 (en) 2008-10-01
KR20050088219A (ko) 2005-09-02
DK1576951T3 (da) 2009-02-02
MY142241A (en) 2010-11-15
DE60323874D1 (de) 2008-11-13
BR0317780A (pt) 2005-11-22
CA2527572C (en) 2010-03-30
BRPI0317780B1 (pt) 2018-11-21
ZA200505399B (en) 2006-04-26
ES2315537T3 (es) 2009-04-01
CN1738602A (zh) 2006-02-22
MXPA05007006A (es) 2005-08-18
KR100804013B1 (ko) 2008-02-18

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