IL152869A0 - Substituted triazolopyrimidines as anticancer agents - Google Patents

Substituted triazolopyrimidines as anticancer agents

Info

Publication number
IL152869A0
IL152869A0 IL15286901A IL15286901A IL152869A0 IL 152869 A0 IL152869 A0 IL 152869A0 IL 15286901 A IL15286901 A IL 15286901A IL 15286901 A IL15286901 A IL 15286901A IL 152869 A0 IL152869 A0 IL 152869A0
Authority
IL
Israel
Prior art keywords
anticancer agents
substituted triazolopyrimidines
triazolopyrimidines
substituted
anticancer
Prior art date
Application number
IL15286901A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of IL152869A0 publication Critical patent/IL152869A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL15286901A 2000-06-30 2001-06-28 Substituted triazolopyrimidines as anticancer agents IL152869A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21558500P 2000-06-30 2000-06-30
PCT/US2001/020672 WO2002002563A2 (fr) 2000-06-30 2001-06-28 Triazolopyrimidines substitues comme agents anticancereux

Publications (1)

Publication Number Publication Date
IL152869A0 true IL152869A0 (en) 2003-06-24

Family

ID=22803554

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15286901A IL152869A0 (en) 2000-06-30 2001-06-28 Substituted triazolopyrimidines as anticancer agents

Country Status (24)

Country Link
US (1) US7329663B2 (fr)
EP (1) EP1307200A2 (fr)
JP (1) JP2004502691A (fr)
KR (1) KR20030013475A (fr)
CN (1) CN1592624A (fr)
AR (1) AR034553A1 (fr)
AU (2) AU2001273062B2 (fr)
BG (1) BG107277A (fr)
BR (1) BR0112038A (fr)
CA (1) CA2413802A1 (fr)
CZ (1) CZ20024150A3 (fr)
EA (1) EA006483B1 (fr)
GE (1) GEP20053688B (fr)
HK (1) HK1052646A1 (fr)
HU (1) HUP0300798A3 (fr)
IL (1) IL152869A0 (fr)
IN (1) IN2003KO00001A (fr)
MX (1) MXPA02011913A (fr)
NO (1) NO20026195L (fr)
NZ (1) NZ523807A (fr)
PL (1) PL360027A1 (fr)
SK (1) SK18412002A3 (fr)
WO (1) WO2002002563A2 (fr)
ZA (1) ZA200300793B (fr)

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DE10121162A1 (de) * 2001-04-30 2002-10-31 Bayer Ag Triazolopyrimidine
DE10124208A1 (de) † 2001-05-18 2002-11-21 Bayer Ag Verwendung von Triazolopyrimidin-Derivaten als Mikrobizide
US20040162286A1 (en) * 2001-07-18 2004-08-19 Tormo I Blasco Jordi Substituted 6-(2-tolyl)-triazolopyrimidines as fungicides
IL163709A0 (en) * 2002-03-21 2005-12-18 Basf Ag Fungicidal triazolopyrimidines, methods for producing the same, use thereof for combating harmful fungiand agents containing said substances
WO2004011467A1 (fr) * 2002-07-29 2004-02-05 Hokko Chemical Industry Co., Ltd. Derives de triazolopyrimidine et fongicides utilises dans l'agriculture et l'horticulture
UA80304C2 (en) * 2002-11-07 2007-09-10 Basf Ag Substituted 6-(2-halogenphenyl)triazolopyrimidines
CN1768060A (zh) * 2003-03-31 2006-05-03 巴斯福股份公司 7－(链烯基氨基)三唑并嘧啶、其生产方法及其在防治有害真菌中的用途以及包含所述三唑并嘧啶的物质
DE10325133A1 (de) * 2003-06-04 2004-12-23 Bayer Cropscience Ag Triazolopyrimidine
EP1644003A1 (fr) * 2003-06-04 2006-04-12 Vernalis (Cambridge) Limited Triazolo ´1,5-a!pyrimidines et leur utilisation en medecine
DE10328171A1 (de) * 2003-06-24 2005-01-13 Bayer Cropscience Ag Triazolopyrimidine
DE10328173A1 (de) * 2003-06-24 2005-01-13 Bayer Cropscience Ag Triazolopyrimidine
DE10328481A1 (de) * 2003-06-25 2005-01-13 Bayer Ag Triazolopyrimidine
US7419982B2 (en) 2003-09-24 2008-09-02 Wyeth Holdings Corporation Crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-N-[(1S)-2,2,2-trifluoro-1-methylethyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine salts
ATE398452T1 (de) 2003-09-24 2008-07-15 Wyeth Corp 6-aryl-7-halo-imidazoä1,2-aüpyrimidine als mittel gegen krebs
PL1680425T3 (pl) 2003-09-24 2007-05-31 Wyeth Corp 6-[(podstawione)fenylo]triazolopirymidyny jako środki przeciwrakowe
EP1674454A4 (fr) * 2003-10-17 2006-12-27 Nippon Kayaku Kk Derive 2-amino- 1,2,4|triazolo 1,5-a|pyrimidine substitue et utilisation de ce derive
JP4606015B2 (ja) * 2003-11-25 2011-01-05 日本化薬株式会社 ［１，２，４］トリアゾロ［１，５−ａ］ピリミジン誘導体の新規医薬用途
MY179926A (en) 2003-12-08 2020-11-19 Wyeth Corp Process for the preparation of tubulin inhibitors
EP1697373A1 (fr) * 2003-12-17 2006-09-06 Basf Aktiengesellschaft 6-(2,4,6-trihalogenophenyl)-triazolopyrimidines, procede pour leur production et leur utilisation pour lutter contre des champignons nuisibles, ainsi qu'agents les contenant
BRPI0417637A (pt) * 2003-12-17 2007-03-27 Basf Ag compostos, processo para preparar os mesmos, agente, semente, e, processo para combater fungos nocivos fitopatogênicos
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WO2005113555A1 (fr) * 2004-05-17 2005-12-01 Basf Aktiengesellschaft Composes triazolopyrimidine et leur utilisation pour reguler des champignons pathogenes
WO2005120233A1 (fr) * 2004-06-09 2005-12-22 Basf Aktiengesellschaft Composes de triazolopyrimidine et leur utilisation pour lutter contre des champignons nocifs
JP2008503538A (ja) * 2004-06-25 2008-02-07 ビーエーエスエフ　アクチェンゲゼルシャフト トリアゾロピリミジン化合物およびそれらの病原性菌類を防除するための使用
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
US20060293345A1 (en) * 2005-05-20 2006-12-28 Christoph Steeneck Heterobicyclic metalloprotease inhibitors
WO2007011759A2 (fr) * 2005-07-15 2007-01-25 Kalypsys, Inc. Inhibiteurs de la kinesine mitotique
CN101370813A (zh) * 2005-12-16 2009-02-18 惠氏公司 用作抗癌药物的6-[(取代的)苯基]三唑并嘧啶类的二聚体和加合物
TW200800026A (en) * 2006-02-28 2008-01-01 Basf Ag Substituted 6-phenyl-7-amino-[1,2,4]-triazolo[1,5-a] pyrimidines and their use for controlling harmful fungi
WO2007116011A2 (fr) * 2006-04-10 2007-10-18 Basf Se Triazolopyrimidines substituées, procédé de fabrication, utilisation dans la lutte contre des champignons parasites et agent contenant ces composés
JP5231829B2 (ja) 2007-02-15 2013-07-10 石原産業株式会社 ピリジル−トリアゾロピリミジン誘導体又はその塩、それらを含有する有害生物防除剤並びにそれらの製造方法
US7776864B2 (en) 2007-08-14 2010-08-17 Bayer Schering Pharma Ag Fused bicyclic pyrimidines
WO2012047856A2 (fr) * 2010-10-04 2012-04-12 Institute For Hepatitis And Virus Research Nouveaux inhibiteurs de la sécrétion d'antigènes du virus de l'hépatite b
WO2013191112A1 (fr) * 2012-06-22 2013-12-27 住友化学株式会社 Composé hétérocyclique fusionné
CN103360398B (zh) * 2013-07-22 2015-03-25 山东大学 一种三唑并嘧啶类hiv-1逆转录酶抑制剂及其制备方法与应用
GB201504565D0 (en) 2015-03-18 2015-05-06 Takeda Pharmaceutical Novel compounds
KR101995533B1 (ko) * 2017-03-21 2019-07-02 한국화학연구원 [1,2,4]트리아졸로[4,3-a]퀴노잘린 아미노 페닐 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 BET 단백질 관련 질환의 예방 또는 치료용 약학적 조성물
WO2020159942A1 (fr) * 2019-01-29 2020-08-06 Tosk, Inc. Modulateurs de pyrazolopyrimidine de ras gtpase
EP4136089A1 (fr) * 2020-04-14 2023-02-22 The Trustees of The University of Pennsylvania Composés de {1,2,4,} triazolo{1,5-a} pyrimidine substitués et leur utilisation dans la stabilisation de microtubules
AU2021264550A1 (en) * 2020-05-01 2022-11-17 Gilead Sciences, Inc. CD73 inhibiting 2,4-dioxopyrimidine compounds
WO2022011171A1 (fr) * 2020-07-08 2022-01-13 Klotho Therapeutics, Inc. Nouveaux composés et méthodes permettant d'augmenter l'expression du gène klotho
WO2023077030A1 (fr) 2021-10-29 2023-05-04 Gilead Sciences, Inc. Composés cd73
WO2023143194A1 (fr) * 2022-01-25 2023-08-03 瑞石生物医药有限公司 Petite molécule antagoniste du ccr4 et son utilisation

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DE55956C (de) CH. GROOMBRIDGE und W. A. SOUTH in London, 40 New Bond Street Bremskurbel für Pferdebahn- und andere Wagen
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Also Published As

Publication number Publication date
HK1052646A1 (zh) 2003-09-26
AU7306201A (en) 2002-01-14
NO20026195L (no) 2003-02-27
WO2002002563A3 (fr) 2003-01-03
EA200300091A1 (ru) 2003-08-28
CA2413802A1 (fr) 2002-01-10
CN1592624A (zh) 2005-03-09
US7329663B2 (en) 2008-02-12
EA006483B1 (ru) 2005-12-29
BG107277A (bg) 2004-01-30
MXPA02011913A (es) 2003-04-22
KR20030013475A (ko) 2003-02-14
HUP0300798A2 (hu) 2003-07-28
NZ523807A (en) 2004-09-24
GEP20053688B (en) 2005-12-12
AU2001273062B2 (en) 2005-11-24
EP1307200A2 (fr) 2003-05-07
IN2003KO00001A (fr) 2005-12-02
ZA200300793B (en) 2004-07-20
BR0112038A (pt) 2003-04-01
WO2002002563A2 (fr) 2002-01-10
US20020068744A1 (en) 2002-06-06
AR034553A1 (es) 2004-03-03
HUP0300798A3 (en) 2006-02-28
NO20026195D0 (no) 2002-12-23
SK18412002A3 (sk) 2003-06-03
PL360027A1 (en) 2004-09-06
CZ20024150A3 (cs) 2003-09-17
JP2004502691A (ja) 2004-01-29

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