IL150822A0 - PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA - Google Patents
PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhAInfo
- Publication number
- IL150822A0 IL150822A0 IL15082201A IL15082201A IL150822A0 IL 150822 A0 IL150822 A0 IL 150822A0 IL 15082201 A IL15082201 A IL 15082201A IL 15082201 A IL15082201 A IL 15082201A IL 150822 A0 IL150822 A0 IL 150822A0
- Authority
- IL
- Israel
- Prior art keywords
- nhha
- proteins
- surface antigen
- neisseria meningitidis
- conserved regions
- Prior art date
Links
Classifications
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
 
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| US17791700P | 2000-01-25 | 2000-01-25 | |
| PCT/AU2001/000069 WO2001055182A1 (en) | 2000-01-25 | 2001-01-25 | PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA | 
Publications (1)
| Publication Number | Publication Date | 
|---|---|
| IL150822A0 true IL150822A0 (en) | 2003-02-12 | 
Family
ID=22650445
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| IL15082201A IL150822A0 (en) | 2000-01-25 | 2001-01-25 | PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA | 
| IL150822A IL150822A (en) | 2000-01-25 | 2002-07-18 | Proteins Containing Preserved Areas of Meningitis Nisaria NhhA Area Antigens for Use as a Vaccine Against Multiple Strains of Meningitis Nisaria | 
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| IL150822A IL150822A (en) | 2000-01-25 | 2002-07-18 | Proteins Containing Preserved Areas of Meningitis Nisaria NhhA Area Antigens for Use as a Vaccine Against Multiple Strains of Meningitis Nisaria | 
Country Status (18)
| Country | Link | 
|---|---|
| US (4) | US7947291B2 (cs) | 
| EP (2) | EP2395013A3 (cs) | 
| JP (3) | JP2003523208A (cs) | 
| KR (1) | KR100698561B1 (cs) | 
| CN (2) | CN1419564A (cs) | 
| AU (1) | AU2818101A (cs) | 
| BR (1) | BR0107857A (cs) | 
| CA (1) | CA2398139A1 (cs) | 
| CZ (1) | CZ304379B6 (cs) | 
| ES (1) | ES2389719T3 (cs) | 
| HU (1) | HUP0300696A3 (cs) | 
| IL (2) | IL150822A0 (cs) | 
| MX (1) | MXPA02007184A (cs) | 
| NO (1) | NO332229B1 (cs) | 
| NZ (1) | NZ520445A (cs) | 
| PL (1) | PL216780B1 (cs) | 
| WO (1) | WO2001055182A1 (cs) | 
| ZA (1) | ZA200206153B (cs) | 
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| AU1979599A (en) * | 1998-01-14 | 1999-08-02 | Chiron S.P.A. | (neisseria meningitidis) antigens | 
| BR9910089A (pt) | 1998-05-01 | 2004-06-08 | Chiron Corp | Composições e antìgenos de neisseria meningitidis | 
| ES2397918T3 (es) * | 1999-04-30 | 2013-03-12 | Novartis Vaccines And Diagnostics S.R.L. | Antígenos Neisseriales conservados | 
| DK2270173T3 (en) * | 1999-05-19 | 2016-03-07 | Glaxosmithkline Biolog Sa | Neisserial combination compositions | 
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens | 
| JP2003523208A (ja) * | 2000-01-25 | 2003-08-05 | ザ ユニバーシティ オブ クイーンズランド | 髄膜炎菌表面抗原NhhAの保存領域を含むタンパク質 | 
| CN1201011C (zh) * | 2000-02-28 | 2005-05-11 | 启龙股份公司 | 奈瑟球菌蛋白质的异源表达 | 
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins | 
| GB0220199D0 (en) * | 2002-08-30 | 2002-10-09 | Univ Utrecht | Mutant protein and refolding method | 
| SI1524993T1 (sl) | 2002-08-02 | 2013-07-31 | Glaxosmithkline Biologicals S.A. | Neisserijski vakcinski sestavki, ki obsegajo kombinacijo antigenov | 
| CN1809380B (zh) | 2002-10-11 | 2010-05-12 | 启龙有限公司 | 广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗 | 
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins | 
| WO2007042326A2 (en) * | 2005-10-14 | 2007-04-19 | Intercell Ag | Neisseria meningitidis antigens | 
| CA2654706A1 (en) | 2006-06-12 | 2007-12-21 | Nathalie Devos | Neisseria meningitidis lipooligosaccharide vaccine | 
| EP2367568A2 (en) | 2008-12-17 | 2011-09-28 | Novartis AG | Meningococcal vaccines including hemoglobin receptor | 
| AU2010227219B2 (en) | 2009-03-24 | 2014-02-27 | Glaxosmithkline Biologicals S.A. | Adjuvanting meningococcal factor H binding protein | 
| US20120064103A1 (en) | 2009-03-24 | 2012-03-15 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates | 
| CA2772103A1 (en) | 2009-08-27 | 2011-03-03 | Novartis Ag | Adjuvant comprising aluminium, oligonucleotide and polycation | 
| BR112012004275A2 (pt) | 2009-08-27 | 2016-11-16 | Novartis Ag | polipeptídios híbridos incluindo sequências meningocócicas de fhbp | 
| AU2010302344A1 (en) | 2009-09-30 | 2012-04-26 | Novartis Ag | Expression of meningococcal fhbp polypeptides | 
| BR112012010531A2 (pt) | 2009-10-27 | 2019-09-24 | Novartis Ag | "polipeptídeos de modificação meningocócica fhbp" | 
| CA2792683A1 (en) | 2010-03-10 | 2011-09-15 | Glaxosmithkline Biologicals S.A. | Neisserial fhbp vaccine composition | 
| BR112012022800A2 (pt) | 2010-03-11 | 2018-05-15 | Glaxosmithkline Biologicals Sa | composição imunogênica ou vacina, cepa bacteriana gram-negativa geneticamente engenheirada, métodos para o tratamento ou prevenção de infecção ou doença, para produzir uma composição imunogênica ou uma vacina, e para preparar uma imunoglobulina, preparação da imunoglobulina, e, preparação farmacêutica | 
| WO2012020326A1 (en) | 2010-03-18 | 2012-02-16 | Novartis Ag | Adjuvanted vaccines for serogroup b meningococcus | 
| WO2011161653A1 (en) | 2010-06-25 | 2011-12-29 | Novartis Ag | Combinations of meningococcal factor h binding proteins | 
| RU2013108881A (ru) * | 2010-07-30 | 2014-09-10 | Гриффит Юниверсити | РЕКОМБИНАНТНЫЕ ПОРИНОВЫЕ БЕЛКИ Por A Neisseria meningitidis | 
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition | 
| AU2011300418B2 (en) | 2010-09-10 | 2016-05-12 | Glaxosmithkline Biologicals Sa | Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom | 
| WO2012054879A1 (en) * | 2010-10-22 | 2012-04-26 | Duke University | Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia | 
| US20150147356A1 (en) | 2011-05-12 | 2015-05-28 | Alan Kimura | Antipyretics to enhance tolerability of vesicle-based vaccines | 
| EP2797624A1 (en) | 2011-12-29 | 2014-11-05 | Novartis AG | Adjuvanted combinations of meningococcal factor h binding proteins | 
| US9657297B2 (en) | 2012-02-02 | 2017-05-23 | Glaxosmithkline Biologicals Sa | Promoters for increased protein expression in meningococcus | 
| EP2823312B1 (en) | 2012-03-08 | 2019-08-07 | GlaxoSmithKline Biologicals SA | In vitro potency assay for protein-based meningococcal vaccines | 
| CA2876138C (en) | 2012-06-14 | 2023-09-19 | Novartis Ag | Vaccines for serogroup x meningococcus | 
| MX2015002717A (es) | 2012-09-06 | 2015-05-15 | Novartis Ag | Vacunas combinadas con meningococo del serogrupo b y toxoides de difteria/tetanos/tosferina. | 
| LT3110442T (lt) | 2014-02-28 | 2020-12-28 | Glaxosmithkline Biologicals Sa | Modifikuoti meningokokinio fhbp polipeptidai | 
| PL3544637T3 (pl) | 2016-11-25 | 2021-06-14 | Glaxosmithkline Biologicals S.A. | Konjugaty natywnego omv-antygenu i ich zastosowanie | 
| EP3544625A2 (en) | 2016-11-25 | 2019-10-02 | GlaxoSmithKline Biologicals S.A. | Immunogenic conjugates and use thereof | 
| WO2024178355A1 (en) * | 2023-02-24 | 2024-08-29 | BioNTech SE | Systems and methods for engineering synthetic antigens to promote tailored immune responses | 
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| US4843000A (en) | 1979-12-26 | 1989-06-27 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay | 
| US4849338A (en) | 1982-07-16 | 1989-07-18 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay | 
| US4550081A (en) | 1980-05-19 | 1985-10-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Non-reverting salmonella | 
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays | 
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus | 
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus | 
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product | 
| EP0273116A3 (en) * | 1986-10-09 | 1990-05-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Gonococcal and meningococcal polypeptides, vaccines and diagnostics | 
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites | 
| US5785973A (en) | 1988-02-01 | 1998-07-28 | Praxis Biologics, Inc. | Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines | 
| EP0407413B1 (de) | 1988-03-24 | 1992-06-03 | ZACH, Johann | Druck- oder kraftmessvorrichtung | 
| ES2070312T5 (es) * | 1988-12-19 | 2003-05-16 | American Cyanamid Co | Vacuna de proteina de membrana exterior meningococica de clase 1. | 
| AU649066B2 (en) | 1990-07-25 | 1994-05-12 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements | 
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets | 
| US5646259A (en) | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins | 
| US6143495A (en) | 1995-11-21 | 2000-11-07 | Yale University | Unimolecular segment amplification and sequencing | 
| GB9611673D0 (en) * | 1996-06-05 | 1996-08-07 | Peptide Therapeutics Ltd | Meningococcal vaccine | 
| JP4472866B2 (ja) | 1997-11-06 | 2010-06-02 | カイロン ソチエタ ア レスポンサビリタ リミタータ | ナイセリア抗原 | 
| GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences | 
| AU1979599A (en) | 1998-01-14 | 1999-08-02 | Chiron S.P.A. | (neisseria meningitidis) antigens | 
| BR9910089A (pt) | 1998-05-01 | 2004-06-08 | Chiron Corp | Composições e antìgenos de neisseria meningitidis | 
| GB9810276D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds | 
| WO2000061165A1 (en) * | 1999-04-13 | 2000-10-19 | Smithkline Beecham Corporation | Conserved adhesin motif and methods of use thereof | 
| ES2397918T3 (es) | 1999-04-30 | 2013-03-12 | Novartis Vaccines And Diagnostics S.R.L. | Antígenos Neisseriales conservados | 
| DK1185691T3 (da) | 1999-04-30 | 2009-06-22 | Novartis Vaccines & Diagnostic | Genomiske neisseriasekvenser og fremgangmåder til anvendelse deraf | 
| GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides | 
| JP2003523208A (ja) | 2000-01-25 | 2003-08-05 | ザ ユニバーシティ オブ クイーンズランド | 髄膜炎菌表面抗原NhhAの保存領域を含むタンパク質 | 
| SI1524993T1 (sl) * | 2002-08-02 | 2013-07-31 | Glaxosmithkline Biologicals S.A. | Neisserijski vakcinski sestavki, ki obsegajo kombinacijo antigenov | 
| CA2550927A1 (en) * | 2003-12-23 | 2005-07-14 | Glaxosmithkline Biologicals S.A. | A gram negative bacterium with reduced lps level in the outer membrane and use thereof for treating gram negative bacterial infection | 
- 
        2001
        - 2001-01-25 JP JP2001561034A patent/JP2003523208A/ja active Pending
- 2001-01-25 CZ CZ2002-2482A patent/CZ304379B6/cs not_active IP Right Cessation
- 2001-01-25 CN CN01807183A patent/CN1419564A/zh active Pending
- 2001-01-25 AU AU28181/01A patent/AU2818101A/en not_active Abandoned
- 2001-01-25 BR BR0107857-7A patent/BR0107857A/pt active Search and Examination
- 2001-01-25 IL IL15082201A patent/IL150822A0/xx unknown
- 2001-01-25 KR KR1020027009512A patent/KR100698561B1/ko not_active Expired - Fee Related
- 2001-01-25 US US09/771,382 patent/US7947291B2/en not_active Expired - Fee Related
- 2001-01-25 CN CN2011102811093A patent/CN102417537A/zh active Pending
- 2001-01-25 EP EP10184045A patent/EP2395013A3/en not_active Withdrawn
- 2001-01-25 EP EP01946868A patent/EP1252182B1/en not_active Expired - Lifetime
- 2001-01-25 PL PL356819A patent/PL216780B1/pl not_active IP Right Cessation
- 2001-01-25 WO PCT/AU2001/000069 patent/WO2001055182A1/en active IP Right Grant
- 2001-01-25 CA CA002398139A patent/CA2398139A1/en not_active Abandoned
- 2001-01-25 HU HU0300696A patent/HUP0300696A3/hu unknown
- 2001-01-25 NZ NZ520445A patent/NZ520445A/en not_active IP Right Cessation
- 2001-01-25 ES ES01946868T patent/ES2389719T3/es not_active Expired - Lifetime
- 2001-01-25 MX MXPA02007184A patent/MXPA02007184A/es active IP Right Grant
 
- 
        2002
        - 2002-07-18 IL IL150822A patent/IL150822A/en not_active IP Right Cessation
- 2002-07-22 NO NO20023487A patent/NO332229B1/no not_active IP Right Cessation
- 2002-08-01 ZA ZA200206153A patent/ZA200206153B/xx unknown
 
- 
        2007
        - 2007-10-31 US US11/933,245 patent/US8367070B2/en not_active Expired - Fee Related
- 2007-10-31 US US11/933,411 patent/US8383790B2/en not_active Expired - Fee Related
 
- 
        2011
        - 2011-09-30 JP JP2011218296A patent/JP2012051902A/ja active Pending
 
- 
        2013
        - 2013-02-01 US US13/757,124 patent/US20130136762A1/en not_active Abandoned
- 2013-09-11 JP JP2013188798A patent/JP2014024849A/ja active Pending
 
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