IL149995A0 - Depsipeptides and pharmaceutical compositions containing the same - Google Patents
Depsipeptides and pharmaceutical compositions containing the sameInfo
- Publication number
- IL149995A0 IL149995A0 IL14999500A IL14999500A IL149995A0 IL 149995 A0 IL149995 A0 IL 149995A0 IL 14999500 A IL14999500 A IL 14999500A IL 14999500 A IL14999500 A IL 14999500A IL 149995 A0 IL149995 A0 IL 149995A0
- Authority
- IL
- Israel
- Prior art keywords
- depsipeptides
- same
- pharmaceutical compositions
- compositions containing
- grant
- Prior art date
Links
- 108010002156 Depsipeptides Proteins 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- -1 FR901228 Chemical class 0.000 abstract 1
- 102000000588 Interleukin-2 Human genes 0.000 abstract 1
- 108010002350 Interleukin-2 Proteins 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000039 congener Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16973199P | 1999-12-08 | 1999-12-08 | |
US19358200P | 2000-03-30 | 2000-03-30 | |
PCT/US2000/033169 WO2001042282A1 (fr) | 1999-12-08 | 2000-12-06 | Depsipeptide et ses congeneres destines a etre utilises en tant qu'immunodepresseurs |
Publications (1)
Publication Number | Publication Date |
---|---|
IL149995A0 true IL149995A0 (en) | 2002-12-01 |
Family
ID=26865325
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14999500A IL149995A0 (en) | 1999-12-08 | 2000-12-06 | Depsipeptides and pharmaceutical compositions containing the same |
IL149995A IL149995A (en) | 1999-12-08 | 2002-06-03 | Depsipeptides and pharmaceutical compositions containing the same |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL149995A IL149995A (en) | 1999-12-08 | 2002-06-03 | Depsipeptides and pharmaceutical compositions containing the same |
Country Status (16)
Country | Link |
---|---|
US (2) | US6403555B1 (fr) |
EP (3) | EP1438966B1 (fr) |
JP (4) | JP4824890B2 (fr) |
KR (1) | KR20020062956A (fr) |
CN (1) | CN1414971A (fr) |
AT (3) | ATE470447T1 (fr) |
AU (1) | AU762525B2 (fr) |
BR (1) | BR0016154A (fr) |
CA (1) | CA2393682C (fr) |
DE (3) | DE60033453T2 (fr) |
DK (1) | DK1438966T3 (fr) |
ES (3) | ES2282751T3 (fr) |
HK (2) | HK1049849B (fr) |
IL (2) | IL149995A0 (fr) |
PT (1) | PT1438966E (fr) |
WO (1) | WO2001042282A1 (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6822267B1 (en) * | 1997-08-20 | 2004-11-23 | Advantest Corporation | Signal transmission circuit, CMOS semiconductor device, and circuit board |
US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US8119159B2 (en) | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
EP1313872A1 (fr) * | 2000-09-01 | 2003-05-28 | Fujisawa Pharmaceutical Co., Ltd. | Procede de preparation de fr901228 |
AU2002243231A1 (en) * | 2000-11-21 | 2002-07-24 | Wake Forest University | Method of treating autoimmune diseases |
US6632553B2 (en) * | 2001-03-27 | 2003-10-14 | Mti Microfuel Cells, Inc. | Methods and apparatuses for managing effluent products in a fuel cell system |
JP4238728B2 (ja) * | 2001-08-21 | 2009-03-18 | アステラス製薬株式会社 | ヒストンデアセチラーゼ阻害剤の医薬用途ならびにその抗腫瘍効果の評価方法 |
US8846039B2 (en) * | 2002-04-26 | 2014-09-30 | Asan Laboratories Company (Cayman), Limited | Method for ameliorating pruritus |
US8946295B2 (en) * | 2002-07-25 | 2015-02-03 | Sunny Pharmtech Inc. | Histone hyperacetylating agents for promoting wound healing and preventing scar formation |
US8163764B2 (en) * | 2002-04-26 | 2012-04-24 | Asan Laboratories Company (Cayman) Limited | Skincare methods |
US20060275370A1 (en) * | 2002-07-25 | 2006-12-07 | Yih-Lin Chung | Method and compositions for treatment of epithelial damage |
US8883148B2 (en) * | 2002-04-26 | 2014-11-11 | Asan Laboratories Company (Cayman), Limited | Prevention of joint destruction |
US6809118B2 (en) * | 2002-07-25 | 2004-10-26 | Yih-Lin Chung | Methods for therapy of radiation cutaneous syndrome |
CA2495354A1 (fr) * | 2002-08-20 | 2004-03-04 | Yamanouchi Pharmaceutical Co., Ltd. | Agent inhibant la degradation de la matrice extracellulaire du cartilage articulaire |
US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
CA2518318A1 (fr) | 2003-03-17 | 2004-09-30 | Takeda San Diego, Inc. | Inhibiteurs d'histone deacetylase |
DE602004027244D1 (de) * | 2003-06-27 | 2010-07-01 | Astellas Pharma Inc | Therapeutisches mittel für ein weichteilsarkom |
WO2005007109A2 (fr) * | 2003-07-09 | 2005-01-27 | Henry Ford Health System | Procedes et compositions destines a la cancerotherapie et mettant en oeuvre un nouvel adenovirus |
WO2005030239A2 (fr) * | 2003-09-25 | 2005-04-07 | Astellas Pharma Inc. | Agent antitumoral |
US20050159470A1 (en) * | 2003-12-19 | 2005-07-21 | Syrrx, Inc. | Histone deacetylase inhibitors |
WO2005066151A2 (fr) * | 2003-12-19 | 2005-07-21 | Takeda San Diego, Inc. | Inhibiteurs d'histone desacetylase |
US20050187148A1 (en) * | 2004-02-25 | 2005-08-25 | Yoshinori Naoe | Antitumor agent |
US7951780B2 (en) * | 2004-02-25 | 2011-05-31 | Astellas Pharma Inc. | Antitumor agent |
EP1812036A2 (fr) * | 2004-11-17 | 2007-08-01 | The University Of Chicago | Inhibiteurs de l'histone desacetylase et leurs methodes d'utilisation |
EP1824831A2 (fr) | 2004-12-16 | 2007-08-29 | Takeda San Diego, Inc. | Inhibiteurs d'histone desacetylase |
JP2008540574A (ja) | 2005-05-11 | 2008-11-20 | タケダ サン ディエゴ インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
GB0511266D0 (en) | 2005-06-02 | 2005-07-13 | Trust | Chemical compounds |
CA2615105A1 (fr) * | 2005-07-14 | 2007-01-25 | Takeda San Diego, Inc. | Inhibiteurs de l'histone deacetylase |
JP2009507081A (ja) * | 2005-09-07 | 2009-02-19 | ブレインセルス,インコーポレイティド | HDac阻害による神経発生の調整 |
CA2630216A1 (fr) * | 2005-11-18 | 2007-05-31 | Gloucester Pharmaceuticals, Inc. | Derives de metabolites de l'inhibiteur de hdac fk228 |
EP1976835A2 (fr) * | 2006-01-13 | 2008-10-08 | Takeda San Diego, Inc. | Inhibiteurs des histone desacetylases |
ES2426445T3 (es) | 2006-04-07 | 2013-10-23 | Merrion Research Iii Limited | Forma de dosificación oral sólida que contiene un potenciador |
EP2012801A4 (fr) | 2006-04-24 | 2009-08-05 | Gloucester Pharmaceuticals Inc | Thérapie de combinaison de gemcitabine |
WO2007146730A2 (fr) | 2006-06-08 | 2007-12-21 | Gloucester Pharmaceuticals | Thérapie à base d'inhibiteurs de désacétylase (dac) |
CA2654566A1 (fr) * | 2006-06-09 | 2007-12-21 | Merrion Research Iii Limited | Forme posologique solide a administrer par voie orale contenant un activateur |
US7883855B2 (en) | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
CA2670223A1 (fr) * | 2006-11-22 | 2008-05-29 | Karus Therapeutics Limited | Depsipeptides et leur utilisation therapeutique |
GB0623388D0 (en) * | 2006-11-23 | 2007-01-03 | Univ Southampton | Chemical compounds |
US7914999B2 (en) | 2006-12-29 | 2011-03-29 | Abbott Laboratories | Non-denaturing lysis reagent |
EP2450049A1 (fr) * | 2006-12-29 | 2012-05-09 | Gloucester Pharmaceuticals, Inc. | Traitements du cancer a base de romidepsine |
CA2674309A1 (fr) | 2006-12-29 | 2008-07-10 | Gloucester Pharmaceuticals, Inc. | Preparation de la romidepsine |
US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
WO2008151306A1 (fr) * | 2007-06-05 | 2008-12-11 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Synthèse de composés cyclodepsipeptide ayant une activité antinéoplasique et/ou antimicrobienne |
GB0715750D0 (en) * | 2007-08-13 | 2007-09-19 | Karus Therapeutics Ltd | Chemical compounds |
CA2709272C (fr) * | 2007-12-19 | 2015-03-10 | Abbott Laboratories | Reactif d'extraction d'un immunosuppresseur pour dosages immunologiques |
US8999383B2 (en) | 2008-05-07 | 2015-04-07 | Merrion Research Iii Limited | Compositions of GnRH related compounds and processes of preparation |
CA2725278A1 (fr) * | 2008-05-22 | 2009-11-26 | Karus Therapeutics Limited | Depsipeptides et leur utilisation therapeutique |
EP2293845A1 (fr) * | 2008-05-22 | 2011-03-16 | Karus Therapeutics Limited | Depsipeptides et leur utilisation thérapeutique |
CA2763299C (fr) * | 2009-06-26 | 2015-11-24 | Asan Laboratories Co., Ltd. | Methode traitement ou d'amelioration de toxicites mucocutanees ou oculaires |
TWI412359B (zh) * | 2009-07-07 | 2013-10-21 | Asan Lab Co Ltd | 組織蛋白去乙醯酵素抑制劑在製備治療或減緩黏膜/皮膚或眼睛毒性或副作用之藥物的用途 |
US9089484B2 (en) | 2010-03-26 | 2015-07-28 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor Xa inhibitors for oral administration |
CN103108648A (zh) | 2010-07-12 | 2013-05-15 | 细胞基因公司 | 罗米地辛固体形式及其用途 |
US8859502B2 (en) | 2010-09-13 | 2014-10-14 | Celgene Corporation | Therapy for MLL-rearranged leukemia |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
WO2012094598A2 (fr) | 2011-01-07 | 2012-07-12 | Merrion Research Iii Limited | Compositions pharmaceutiques de fer pour administration orale |
JP6214397B2 (ja) * | 2011-09-30 | 2017-10-18 | 国立大学法人東北大学 | 新規ホスファチジルイノシトール3キナーゼ阻害剤及び医薬組成物 |
JP6492003B2 (ja) | 2012-03-30 | 2019-03-27 | ワシントン・ユニバーシティWashington University | 発作を減少させるためおよび神経変性症候群を改質するためにタウ発現を調節する方法 |
AU2013202506B2 (en) | 2012-09-07 | 2015-06-18 | Celgene Corporation | Resistance biomarkers for hdac inhibitors |
AU2013202507B9 (en) | 2012-11-14 | 2015-08-13 | Celgene Corporation | Inhibition of drug resistant cancer cells |
TW202246503A (zh) | 2013-07-19 | 2022-12-01 | 美商百健Ma公司 | 用於調節τ蛋白表現之組合物 |
NZ630311A (en) | 2013-12-27 | 2016-03-31 | Celgene Corp | Romidepsin formulations and uses thereof |
KR20150140177A (ko) * | 2014-06-05 | 2015-12-15 | 한미약품 주식회사 | 단백질 및 펩타이드의 면역원성을 감소시키는 방법 |
US10265384B2 (en) | 2015-01-29 | 2019-04-23 | Novo Nordisk A/S | Tablets comprising GLP-1 agonist and enteric coating |
CN110760564A (zh) * | 2019-10-16 | 2020-02-07 | 菲诺克生物科技(上海)有限公司 | 细胞周期检测方法及其所用试剂与试剂盒 |
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US4268516A (en) | 1978-10-11 | 1981-05-19 | Pfizer Inc. | [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents |
US4950649A (en) * | 1980-09-12 | 1990-08-21 | University Of Illinois | Didemnins and nordidemnins |
GB8817743D0 (en) * | 1988-07-26 | 1988-09-01 | Fujisawa Pharmaceutical Co | Fr901228 substance & preparation thereof |
AU3972193A (en) | 1992-04-07 | 1993-11-08 | Scripps Research Institute, The | Method for inducing tolerance to an antigen using butyrate |
ZA946765B (en) | 1993-09-02 | 1996-02-15 | Dartmouth College | Methods of prolonged suppression of humoral immunity |
US5591717A (en) | 1994-04-06 | 1997-01-07 | Rojko; Jennifer L. | Branched apogenic peptide for inducing apoptosis |
WO1995033823A1 (fr) | 1994-06-03 | 1995-12-14 | The United States Of America, Represented By The Secretary Of The Navy | Procedes de stimulation selective de la proliferation des cellules t |
US5843943A (en) | 1994-12-29 | 1998-12-01 | The Regents Of The University Of California | Compounds for inhibition of ceramide-mediated signal transduction |
US5962019A (en) | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5891653A (en) | 1995-12-29 | 1999-04-06 | Attfield; Derrick Cecil | Method of suppressing graft rejection by means of stress proteins |
US6777217B1 (en) * | 1996-03-26 | 2004-08-17 | President And Fellows Of Harvard College | Histone deacetylases, and uses related thereto |
EP0972012A4 (fr) | 1997-03-03 | 2004-09-29 | Univ Duke | Immunodepression |
DE19713626A1 (de) * | 1997-04-02 | 1998-10-08 | Bayer Ag | Neue Thiodepsipeptide zur Bekämpfung von Endoparasiten und ein einfaches Verfahren zu ihrer Herstellung |
WO1998046640A2 (fr) | 1997-04-15 | 1998-10-22 | Coulter International Corp. | Procedes et compositions permettant d'induire l'immunosuppression |
EP1010705A4 (fr) | 1997-09-02 | 2004-09-15 | Sumitomo Pharma | Derives tetrapeptides cycliques et leur utilisation medicinale |
AU9395998A (en) | 1997-09-17 | 1999-04-05 | Genentech Inc. | Compositions and methods for the treatment of immune related diseases |
AU9398398A (en) | 1997-09-22 | 1999-04-12 | Sloan-Kettering Institute For Cancer Research | Reverse prenyl compounds as immunosuppressants |
WO1999025703A1 (fr) | 1997-11-14 | 1999-05-27 | Merck & Co., Inc. | Triterpenes tetracycliques immunodepresseurs |
AU1864999A (en) | 1997-12-15 | 1999-07-05 | Universite Laval | Methods and compositions for improving the success of cell transplantation in a host |
JPH11180873A (ja) | 1997-12-22 | 1999-07-06 | Kaken Shoyaku Kk | NF−κB活性阻害剤 |
US6001815A (en) * | 1997-12-25 | 1999-12-14 | Nisshin Flour Milling Co., Ltd. | Depsipeptides containing N-substituted glycine residue |
US6211145B1 (en) * | 1997-12-25 | 2001-04-03 | Nisshin Flour Milling Co., Ltd. | Bicyclic depsipeptides |
EP0931792B1 (fr) * | 1998-01-27 | 2004-01-07 | Nisshin Seifun Group Inc. | Depsipeptides comportant des acides aminés non naturelles |
US6287843B1 (en) | 1998-04-03 | 2001-09-11 | Pioneer Hi-Bred International, Inc. | Maize histone deacetylases and their use |
KR100611265B1 (ko) * | 1999-01-13 | 2006-08-10 | 아스텔라스세이야쿠 가부시키가이샤 | 신규 뎁시펩티드 화합물 |
-
2000
- 2000-12-06 ES ES04007814T patent/ES2282751T3/es not_active Expired - Lifetime
- 2000-12-06 JP JP2001543579A patent/JP4824890B2/ja not_active Expired - Fee Related
- 2000-12-06 ES ES00983997T patent/ES2225282T3/es not_active Expired - Lifetime
- 2000-12-06 BR BR0016154-3A patent/BR0016154A/pt not_active Application Discontinuation
- 2000-12-06 PT PT04007814T patent/PT1438966E/pt unknown
- 2000-12-06 DE DE60033453T patent/DE60033453T2/de not_active Expired - Lifetime
- 2000-12-06 AT AT07002930T patent/ATE470447T1/de not_active IP Right Cessation
- 2000-12-06 IL IL14999500A patent/IL149995A0/xx unknown
- 2000-12-06 EP EP04007814A patent/EP1438966B1/fr not_active Expired - Lifetime
- 2000-12-06 AT AT00983997T patent/ATE269354T1/de not_active IP Right Cessation
- 2000-12-06 EP EP07002930A patent/EP1779859B1/fr not_active Expired - Lifetime
- 2000-12-06 CA CA2393682A patent/CA2393682C/fr not_active Expired - Fee Related
- 2000-12-06 CN CN00817856A patent/CN1414971A/zh active Pending
- 2000-12-06 ES ES07002930T patent/ES2347284T3/es not_active Expired - Lifetime
- 2000-12-06 AT AT04007814T patent/ATE353663T1/de not_active IP Right Cessation
- 2000-12-06 WO PCT/US2000/033169 patent/WO2001042282A1/fr active IP Right Grant
- 2000-12-06 KR KR1020027007258A patent/KR20020062956A/ko not_active Application Discontinuation
- 2000-12-06 US US09/732,183 patent/US6403555B1/en not_active Expired - Lifetime
- 2000-12-06 AU AU20680/01A patent/AU762525B2/en not_active Ceased
- 2000-12-06 DE DE60044542T patent/DE60044542D1/de not_active Expired - Lifetime
- 2000-12-06 DE DE60011678T patent/DE60011678T2/de not_active Expired - Lifetime
- 2000-12-06 DK DK04007814T patent/DK1438966T3/da active
- 2000-12-06 EP EP00983997A patent/EP1246839B1/fr not_active Revoked
-
2002
- 2002-04-02 US US10/115,576 patent/US6548479B1/en not_active Expired - Lifetime
- 2002-06-03 IL IL149995A patent/IL149995A/en not_active IP Right Cessation
-
2003
- 2003-03-18 HK HK03101982.5A patent/HK1049849B/zh not_active IP Right Cessation
-
2005
- 2005-01-21 HK HK05100599A patent/HK1070268A1/xx not_active IP Right Cessation
-
2011
- 2011-01-28 JP JP2011017260A patent/JP2011084585A/ja not_active Withdrawn
-
2013
- 2013-03-06 JP JP2013043969A patent/JP2013107902A/ja not_active Withdrawn
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2014
- 2014-07-31 JP JP2014155914A patent/JP2014205714A/ja not_active Withdrawn
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