IL148343A0 - Injectable buprenorphine microparticle compositions and their use - Google Patents

Injectable buprenorphine microparticle compositions and their use

Info

Publication number
IL148343A0
IL148343A0 IL14834300A IL14834300A IL148343A0 IL 148343 A0 IL148343 A0 IL 148343A0 IL 14834300 A IL14834300 A IL 14834300A IL 14834300 A IL14834300 A IL 14834300A IL 148343 A0 IL148343 A0 IL 148343A0
Authority
IL
Israel
Prior art keywords
methadone
partial
opioid antagonist
opioid agonist
opioid
Prior art date
Application number
IL14834300A
Other languages
English (en)
Original Assignee
Southern Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Res Inst filed Critical Southern Res Inst
Publication of IL148343A0 publication Critical patent/IL148343A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14834300A 1999-08-27 2000-08-25 Injectable buprenorphine microparticle compositions and their use IL148343A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15111299P 1999-08-27 1999-08-27
PCT/US2000/023390 WO2001015699A1 (en) 1999-08-27 2000-08-25 Injectable buprenorphine microparticle compositions and their use

Publications (1)

Publication Number Publication Date
IL148343A0 true IL148343A0 (en) 2002-09-12

Family

ID=22537367

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14834300A IL148343A0 (en) 1999-08-27 2000-08-25 Injectable buprenorphine microparticle compositions and their use
IL148343A IL148343A (en) 1999-08-27 2002-02-24 Injection compounds containing tiny buprenorphine particles, and their uses

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL148343A IL148343A (en) 1999-08-27 2002-02-24 Injection compounds containing tiny buprenorphine particles, and their uses

Country Status (24)

Country Link
US (2) US6495155B1 (pt)
EP (1) EP1212061B1 (pt)
JP (1) JP4913298B2 (pt)
KR (1) KR100730440B1 (pt)
CN (2) CN100387228C (pt)
AT (1) ATE280579T1 (pt)
AU (1) AU765496C (pt)
BR (1) BR0013650A (pt)
CA (1) CA2382577C (pt)
CY (1) CY1106043T1 (pt)
CZ (1) CZ2002728A3 (pt)
DE (1) DE60015370T2 (pt)
EA (1) EA009080B1 (pt)
ES (1) ES2230154T3 (pt)
HK (1) HK1046858B (pt)
HU (1) HUP0203613A3 (pt)
IL (2) IL148343A0 (pt)
MX (1) MXPA02002105A (pt)
NO (2) NO322650B1 (pt)
NZ (1) NZ517997A (pt)
PL (1) PL198334B1 (pt)
PT (1) PT1212061E (pt)
RO (1) RO121631B1 (pt)
WO (1) WO2001015699A1 (pt)

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US6495164B1 (en) * 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
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US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
EP1404332A1 (en) * 2001-07-06 2004-04-07 Penwest Pharmaceuticals Company Methods of making sustained release formulations of oxymorphone related applications
US20030091635A1 (en) * 2001-09-26 2003-05-15 Baichwal Anand R. Opioid formulations having reduced potential for abuse
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
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US7041320B1 (en) * 2002-05-31 2006-05-09 Biotek, Inc. High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
US7842377B2 (en) * 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
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WO2004078178A1 (en) * 2003-03-03 2004-09-16 Markus Heilig Buprenorphine compounds for treatment of alcohol dependence and excessive alcohol use
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JP5502751B2 (ja) * 2007-12-20 2014-05-28 エボニック コーポレイション 低残留溶媒濃度を有する微粒子を調製するためのプロセス
PL2326313T3 (pl) 2008-09-24 2015-08-31 Evonik Roehm Gmbh Kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu dla nieopioidów z odpornością przed wpływem etanolu
CA2738078C (en) * 2008-09-24 2015-12-29 Evonik Roehm Gmbh Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
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US20100268191A1 (en) * 2009-04-21 2010-10-21 Medtronic Vascular, Inc. Drug Delivery Catheter using Frangible Microcapsules and Delivery Method
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US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
US9566241B2 (en) 2012-02-21 2017-02-14 Auburn University Buprenorphine nanoparticle composition and methods thereof
WO2013156850A1 (en) 2012-04-17 2013-10-24 Purdue Pharma L.P. Systems and methods for treating an opioid-induced adverse pharmacodynamic response
CN102836131A (zh) * 2012-09-28 2012-12-26 山东大学 丁丙诺啡皮下注射用缓释微球制剂及其制备方法
US9636308B2 (en) 2013-03-15 2017-05-02 Oakwood Laboratories LLC High drug load buprenorphine microspheres and method of producing same
US9393211B2 (en) * 2013-03-15 2016-07-19 Oakwood Laboratories LLC High drug load buprenorphine microspheres and method of producing same
JP6135292B2 (ja) * 2013-05-10 2017-05-31 ニプロ株式会社 マイクロカプセル製剤の製造方法
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
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Also Published As

Publication number Publication date
DE60015370T2 (de) 2006-03-09
CA2382577C (en) 2008-01-22
HUP0203613A3 (en) 2005-01-28
AU765496B2 (en) 2003-09-18
US20030152638A1 (en) 2003-08-14
CY1106043T1 (el) 2011-04-06
RO121631B1 (ro) 2008-01-30
ES2230154T3 (es) 2005-05-01
DE60015370D1 (de) 2004-12-02
AU7075100A (en) 2001-03-26
HUP0203613A2 (hu) 2003-02-28
KR20020053057A (ko) 2002-07-04
PL198334B1 (pl) 2008-06-30
JP2003508439A (ja) 2003-03-04
NZ517997A (en) 2002-11-26
CZ2002728A3 (cs) 2002-08-14
HK1046858A1 (en) 2003-01-30
EP1212061B1 (en) 2004-10-27
CN1248689C (zh) 2006-04-05
EA009080B1 (ru) 2007-10-26
EP1212061A1 (en) 2002-06-12
US6495155B1 (en) 2002-12-17
EA200200295A1 (ru) 2002-08-29
MXPA02002105A (es) 2003-12-11
NO20063239L (no) 2002-04-03
HK1046858B (zh) 2005-03-24
NO322650B1 (no) 2006-11-13
CN1382051A (zh) 2002-11-27
AU765496C (en) 2005-08-25
KR100730440B1 (ko) 2007-06-19
US7473431B2 (en) 2009-01-06
JP4913298B2 (ja) 2012-04-11
CN1788721A (zh) 2006-06-21
NO20020924D0 (no) 2002-02-26
PL354977A1 (en) 2004-03-22
CN100387228C (zh) 2008-05-14
WO2001015699A1 (en) 2001-03-08
NO20020924L (no) 2002-04-03
CA2382577A1 (en) 2001-03-08
ATE280579T1 (de) 2004-11-15
PT1212061E (pt) 2005-01-31
IL148343A (en) 2008-03-20
BR0013650A (pt) 2002-05-07

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