NO20063239L - Injiserbare mikropartikkelpreparater - Google Patents

Injiserbare mikropartikkelpreparater

Info

Publication number
NO20063239L
NO20063239L NO20063239A NO20063239A NO20063239L NO 20063239 L NO20063239 L NO 20063239L NO 20063239 A NO20063239 A NO 20063239A NO 20063239 A NO20063239 A NO 20063239A NO 20063239 L NO20063239 L NO 20063239L
Authority
NO
Norway
Prior art keywords
partially
opioid
drug
opioid antagonist
opioid agonist
Prior art date
Application number
NO20063239A
Other languages
English (en)
Inventor
Thomas R Tice
Jay K Staas
Teresa M Ferrell
Peter Markland
Original Assignee
Brookwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20063239L publication Critical patent/NO20063239L/no
Application filed by Brookwood Pharmaceuticals Inc filed Critical Brookwood Pharmaceuticals Inc

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det tilveiebringes en injiserbar saktefiigjørende, delvis opioid agonist- eller opioid antagonistformulering omfattende en delvis opioid agonist eller opioid antagonist i en poly(D,L-laktid)-eksipiens med en liten mengde gjenværende etylacetat. Ved inttamuskulær injeksjon av preparatet fi-igjøres en delvis opioid agonist eller opioid antagonist på en konttollert måte over et utvidet tidsrom. Preparatet kan anvendes ved behandling av heroinavhengige og alkoholikere for å redusere forbruket av det misbrukte stoffet. Av spesieU interesse er medikamentene buprenorfin, metadon og nalttekson.
NO20063239A 1999-08-27 2006-07-12 Injiserbare mikropartikkelpreparater NO20063239L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15111299P 1999-08-27 1999-08-27
PCT/US2000/023390 WO2001015699A1 (en) 1999-08-27 2000-08-25 Injectable buprenorphine microparticle compositions and their use

Publications (1)

Publication Number Publication Date
NO20063239L true NO20063239L (no) 2002-04-03

Family

ID=22537367

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20020924A NO322650B1 (no) 1999-08-27 2002-02-26 Injiserbare buprenorfinmikropartikkelpreparater og deres anvendelse
NO20063239A NO20063239L (no) 1999-08-27 2006-07-12 Injiserbare mikropartikkelpreparater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20020924A NO322650B1 (no) 1999-08-27 2002-02-26 Injiserbare buprenorfinmikropartikkelpreparater og deres anvendelse

Country Status (24)

Country Link
US (2) US6495155B1 (no)
EP (1) EP1212061B1 (no)
JP (1) JP4913298B2 (no)
KR (1) KR100730440B1 (no)
CN (2) CN1248689C (no)
AT (1) ATE280579T1 (no)
AU (1) AU765496C (no)
BR (1) BR0013650A (no)
CA (1) CA2382577C (no)
CY (1) CY1106043T1 (no)
CZ (1) CZ2002728A3 (no)
DE (1) DE60015370T2 (no)
EA (1) EA009080B1 (no)
ES (1) ES2230154T3 (no)
HK (1) HK1046858B (no)
HU (1) HUP0203613A3 (no)
IL (2) IL148343A0 (no)
MX (1) MXPA02002105A (no)
NO (2) NO322650B1 (no)
NZ (1) NZ517997A (no)
PL (1) PL198334B1 (no)
PT (1) PT1212061E (no)
RO (1) RO121631B1 (no)
WO (1) WO2001015699A1 (no)

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CN104984343B (zh) * 2008-09-24 2019-04-02 赢创罗姆有限公司 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物
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Also Published As

Publication number Publication date
CZ2002728A3 (cs) 2002-08-14
EA009080B1 (ru) 2007-10-26
AU765496B2 (en) 2003-09-18
MXPA02002105A (es) 2003-12-11
EP1212061A1 (en) 2002-06-12
PT1212061E (pt) 2005-01-31
NZ517997A (en) 2002-11-26
NO20020924L (no) 2002-04-03
CN100387228C (zh) 2008-05-14
JP4913298B2 (ja) 2012-04-11
AU7075100A (en) 2001-03-26
HK1046858B (zh) 2005-03-24
US6495155B1 (en) 2002-12-17
US20030152638A1 (en) 2003-08-14
CN1382051A (zh) 2002-11-27
CN1248689C (zh) 2006-04-05
CA2382577A1 (en) 2001-03-08
JP2003508439A (ja) 2003-03-04
IL148343A0 (en) 2002-09-12
NO20020924D0 (no) 2002-02-26
ES2230154T3 (es) 2005-05-01
CN1788721A (zh) 2006-06-21
WO2001015699A1 (en) 2001-03-08
PL198334B1 (pl) 2008-06-30
EA200200295A1 (ru) 2002-08-29
US7473431B2 (en) 2009-01-06
NO322650B1 (no) 2006-11-13
IL148343A (en) 2008-03-20
HK1046858A1 (en) 2003-01-30
PL354977A1 (en) 2004-03-22
HUP0203613A3 (en) 2005-01-28
ATE280579T1 (de) 2004-11-15
HUP0203613A2 (hu) 2003-02-28
BR0013650A (pt) 2002-05-07
DE60015370T2 (de) 2006-03-09
DE60015370D1 (de) 2004-12-02
CA2382577C (en) 2008-01-22
KR20020053057A (ko) 2002-07-04
EP1212061B1 (en) 2004-10-27
CY1106043T1 (el) 2011-04-06
KR100730440B1 (ko) 2007-06-19
AU765496C (en) 2005-08-25
RO121631B1 (ro) 2008-01-30

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