IL145166A0 - Biphenyl derivatives as antagonists of the neurokinine-1 receptor - Google Patents
Biphenyl derivatives as antagonists of the neurokinine-1 receptorInfo
- Publication number
- IL145166A0 IL145166A0 IL14516600A IL14516600A IL145166A0 IL 145166 A0 IL145166 A0 IL 145166A0 IL 14516600 A IL14516600 A IL 14516600A IL 14516600 A IL14516600 A IL 14516600A IL 145166 A0 IL145166 A0 IL 145166A0
- Authority
- IL
- Israel
- Prior art keywords
- neurokinine
- antagonists
- receptor
- biphenyl derivatives
- biphenyl
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/44—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/66—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99104626 | 1999-03-09 | ||
PCT/EP2000/001668 WO2000053572A1 (en) | 1999-03-09 | 2000-02-28 | Biphenyl derivatives as antagonists of the neurokinine-1 receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
IL145166A0 true IL145166A0 (en) | 2002-06-30 |
Family
ID=8237723
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14516600A IL145166A0 (en) | 1999-03-09 | 2000-02-28 | Biphenyl derivatives as antagonists of the neurokinine-1 receptor |
IL145166A IL145166A (en) | 1999-03-09 | 2001-08-28 | History of biphenyl used as neurokinin-1 receptor antagonists |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL145166A IL145166A (en) | 1999-03-09 | 2001-08-28 | History of biphenyl used as neurokinin-1 receptor antagonists |
Country Status (33)
Country | Link |
---|---|
US (2) | US6291465B1 (pt) |
EP (1) | EP1171419B1 (pt) |
JP (1) | JP3839668B2 (pt) |
KR (1) | KR100473247B1 (pt) |
CN (1) | CN1152006C (pt) |
AR (1) | AR043273A1 (pt) |
AT (1) | ATE286018T1 (pt) |
AU (1) | AU767449B2 (pt) |
BR (1) | BR0008862A (pt) |
CA (1) | CA2366205C (pt) |
CO (1) | CO5160261A1 (pt) |
CZ (1) | CZ20013190A3 (pt) |
DE (1) | DE60017110T2 (pt) |
ES (1) | ES2233338T3 (pt) |
HK (1) | HK1045684B (pt) |
HR (1) | HRP20010629A2 (pt) |
HU (1) | HUP0201710A3 (pt) |
IL (2) | IL145166A0 (pt) |
JO (1) | JO2235B1 (pt) |
MA (1) | MA26778A1 (pt) |
MY (1) | MY121145A (pt) |
NO (1) | NO20014356D0 (pt) |
NZ (1) | NZ513824A (pt) |
PE (1) | PE20001549A1 (pt) |
PL (1) | PL201681B1 (pt) |
PT (1) | PT1171419E (pt) |
RU (1) | RU2238266C2 (pt) |
SI (1) | SI1171419T1 (pt) |
TR (1) | TR200102585T2 (pt) |
UY (1) | UY26051A1 (pt) |
WO (1) | WO2000053572A1 (pt) |
YU (1) | YU64901A (pt) |
ZA (1) | ZA200107259B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000050398A2 (en) | 1999-02-24 | 2000-08-31 | F. Hoffmann-La Roche Ag | Phenyl- and pyridinyl derivatives as neurokinin 1 antagonists |
AUPQ514600A0 (en) | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
TWI287003B (en) * | 2000-07-24 | 2007-09-21 | Hoffmann La Roche | 4-phenyl-pyridine derivatives |
US6642226B2 (en) | 2001-02-06 | 2003-11-04 | Hoffman-La Roche Inc. | Substituted phenyl-piperidine methanone compounds |
US6531597B2 (en) * | 2001-02-13 | 2003-03-11 | Hoffmann-La Roche Inc. | Process for preparation of 2-phenyl acetic acid derivatives |
WO2003077874A2 (en) | 2002-03-13 | 2003-09-25 | The University Of Tennessee Research Foundation | Substituted tetrahydroisoquinoline compounds, methods of making, and their use |
US7705002B2 (en) | 2005-05-19 | 2010-04-27 | Vertex Pharmaceuticals Incorporated | Biaryls useful as modulators of ion channels |
US7880008B2 (en) | 2005-05-31 | 2011-02-01 | Vertex Pharmaceuticals Incorporated | Heterocycles useful as modulators of ion channels |
WO2013004766A1 (en) | 2011-07-04 | 2013-01-10 | Ferrari Giulio | Nk-1 receptor antagonists for treating corneal neovascularisation |
CN114853634A (zh) * | 2016-05-23 | 2022-08-05 | 中国医学科学院药物研究所 | 烟醇醚类衍生物、及其制法和药物组合物与用途 |
EP4371613A3 (en) | 2018-02-26 | 2024-07-24 | Ospedale San Raffaele S.r.l. | Compounds for use in the treatment of ocular pain |
WO2021180885A1 (en) | 2020-03-11 | 2021-09-16 | Ospedale San Raffaele S.R.L. | Treatment of stem cell deficiency |
CN115466195B (zh) * | 2022-09-15 | 2024-04-19 | 中国科学院成都生物研究所 | 一类联苯类酰胺化合物及其制备方法和应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06227913A (ja) * | 1993-02-03 | 1994-08-16 | Sumitomo Chem Co Ltd | 安息香酸誘導体を有効成分とする植物病害防除剤 |
IL111960A (en) | 1993-12-17 | 1999-12-22 | Merck & Co Inc | Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them |
SG52217A1 (en) | 1993-12-29 | 1998-09-28 | Merck Sharp & Dohme | Substituted morpholine derivatives and their use as therapeutic agents |
IL112778A0 (en) | 1994-03-04 | 1995-05-26 | Merck & Co Inc | Substituted heterocycles, their preparation and pharmaceutical compositions containing them |
JP3839518B2 (ja) * | 1996-03-27 | 2006-11-01 | ポーラ化成工業株式会社 | 抗真菌剤 |
EP0975598A1 (en) | 1997-04-18 | 2000-02-02 | Pfizer Inc. | Process and intermediates for the preparation of 4'-trifluoromethyl-biphenyl-2-carboxylic acid (1,2,3,4-tetrahydro-isoquinolin-6-yl)-amide |
US5972938A (en) | 1997-12-01 | 1999-10-26 | Merck & Co., Inc. | Method for treating or preventing psychoimmunological disorders |
EP1035115B1 (en) * | 1999-02-24 | 2004-09-29 | F. Hoffmann-La Roche Ag | 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists |
-
2000
- 2000-02-25 US US09/513,147 patent/US6291465B1/en not_active Expired - Fee Related
- 2000-02-28 SI SI200030598T patent/SI1171419T1/xx unknown
- 2000-02-28 WO PCT/EP2000/001668 patent/WO2000053572A1/en active IP Right Grant
- 2000-02-28 IL IL14516600A patent/IL145166A0/xx active IP Right Grant
- 2000-02-28 CZ CZ20013190A patent/CZ20013190A3/cs unknown
- 2000-02-28 AT AT00909264T patent/ATE286018T1/de not_active IP Right Cessation
- 2000-02-28 BR BR0008862-5A patent/BR0008862A/pt not_active Application Discontinuation
- 2000-02-28 KR KR10-2001-7011407A patent/KR100473247B1/ko not_active IP Right Cessation
- 2000-02-28 NZ NZ513824A patent/NZ513824A/xx unknown
- 2000-02-28 CA CA002366205A patent/CA2366205C/en not_active Expired - Fee Related
- 2000-02-28 DE DE60017110T patent/DE60017110T2/de not_active Expired - Lifetime
- 2000-02-28 AU AU31612/00A patent/AU767449B2/en not_active Ceased
- 2000-02-28 PT PT00909264T patent/PT1171419E/pt unknown
- 2000-02-28 ES ES00909264T patent/ES2233338T3/es not_active Expired - Lifetime
- 2000-02-28 CN CNB008047812A patent/CN1152006C/zh not_active Expired - Fee Related
- 2000-02-28 YU YU64901A patent/YU64901A/sh unknown
- 2000-02-28 HU HU0201710A patent/HUP0201710A3/hu unknown
- 2000-02-28 RU RU2001126547A patent/RU2238266C2/ru not_active IP Right Cessation
- 2000-02-28 EP EP00909264A patent/EP1171419B1/en not_active Expired - Lifetime
- 2000-02-28 TR TR2001/02585T patent/TR200102585T2/xx unknown
- 2000-02-28 PL PL350536A patent/PL201681B1/pl not_active IP Right Cessation
- 2000-02-28 JP JP2000604013A patent/JP3839668B2/ja not_active Expired - Fee Related
- 2000-03-02 JO JO200017A patent/JO2235B1/en active
- 2000-03-03 PE PE2000000177A patent/PE20001549A1/es not_active Application Discontinuation
- 2000-03-06 MY MYPI20000864A patent/MY121145A/en unknown
- 2000-03-06 CO CO00016011A patent/CO5160261A1/es unknown
- 2000-03-07 AR ARP000101001A patent/AR043273A1/es not_active Application Discontinuation
- 2000-03-08 UY UY26051A patent/UY26051A1/es unknown
-
2001
- 2001-06-21 US US09/886,669 patent/US6552088B2/en not_active Expired - Fee Related
- 2001-08-28 HR HR20010629A patent/HRP20010629A2/hr not_active Application Discontinuation
- 2001-08-28 IL IL145166A patent/IL145166A/en not_active IP Right Cessation
- 2001-08-31 ZA ZA200107259A patent/ZA200107259B/en unknown
- 2001-09-07 MA MA26322A patent/MA26778A1/fr unknown
- 2001-09-07 NO NO20014356A patent/NO20014356D0/no not_active Application Discontinuation
-
2002
- 2002-09-26 HK HK02107102.8A patent/HK1045684B/zh not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP2001002223A0 (en) | Substituted bicyclic derivatives useful as anticancer agents | |
SI1224175T1 (en) | Benzodiazepine derivatives as metabotropic glutamate receptor antagonists | |
SI1224174T1 (en) | Benzodiazepine derivatives as metabotropic glutamate receptor antagonists | |
HK1076459A1 (en) | 4-Phenyl-pyridine derivatives as neurokinin-1 receptor antagonists | |
PL356990A1 (en) | Isoxazolecarboxamide derivatives as alpha1-adrenergic receptor antagonists | |
IL152700A0 (en) | Substituted 1-aminoalkyl-lactams and their use as muscarinc receptor antagonists | |
IL153837A0 (en) | 4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists | |
IL135863A0 (en) | Cyclopentene derivatives useful as antagonists of the motilin receptor | |
IL145166A0 (en) | Biphenyl derivatives as antagonists of the neurokinine-1 receptor | |
IL148623A0 (en) | Thienoisoxazolyl-and thienylpyrazolyl-phenoxy substituted propyl derivatives useful as d4 antagonists | |
PL370799A1 (en) | Aminotetralin derivatives as muscarinic receptor antagonists | |
IL146151A0 (en) | Human-g-protein receptor | |
PL352213A1 (en) | Antagonistic compounds of the il-8 receptor | |
IL144299A0 (en) | N-triazolymethyl-piperazine derivatives as neurokinin receptor antagonists | |
PL330708A1 (en) | Derivatives of indolydine useful as antagonists of 5-ht-2c receptor | |
AU2001250820A1 (en) | Novel cyclohexene derivatives useful as antagonists of the motilin receptor | |
PL338453A1 (en) | 2-acylaminopropanoamines as antagonists of the tachykinin receptor | |
AU2001247357A1 (en) | Novel cyclobutene derivatives useful as antagonists of the motilin receptor | |
AU2001249144A1 (en) | Novel cyclopentene derivatives useful as antagonists of the motilin receptor | |
AU1100300A (en) | Piperidyloxadiazoles as dopamine receptor antagonists | |
PL338456A1 (en) | 2-acylaminopropanoamines as antagonists of the tachykinin receptor | |
AU2574801A (en) | Selective iGLUR5 receptor antagonists | |
EP1169042A4 (en) | DIBENZO-AZEPINE DERIVATIVES AS ANTAGONISTS OF THE ALPHA V INTEGRIN RECEPTOR | |
PL352222A1 (en) | Antagonists of the il-8 receptor | |
AU2512800A (en) | Alpha1-adrenergic receptor antagonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed |