AU2001247357A1 - Novel cyclobutene derivatives useful as antagonists of the motilin receptor - Google Patents
Novel cyclobutene derivatives useful as antagonists of the motilin receptorInfo
- Publication number
- AU2001247357A1 AU2001247357A1 AU2001247357A AU4735701A AU2001247357A1 AU 2001247357 A1 AU2001247357 A1 AU 2001247357A1 AU 2001247357 A AU2001247357 A AU 2001247357A AU 4735701 A AU4735701 A AU 4735701A AU 2001247357 A1 AU2001247357 A1 AU 2001247357A1
- Authority
- AU
- Australia
- Prior art keywords
- antagonists
- novel
- derivatives useful
- motilin receptor
- cyclobutene derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18891900P | 2000-03-13 | 2000-03-13 | |
US60188919 | 2000-03-13 | ||
PCT/US2001/007704 WO2001068622A1 (en) | 2000-03-13 | 2001-03-09 | Novel cyclobutene derivatives useful as antagonists of the motilin receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001247357A1 true AU2001247357A1 (en) | 2001-09-24 |
Family
ID=22695097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001247357A Abandoned AU2001247357A1 (en) | 2000-03-13 | 2001-03-09 | Novel cyclobutene derivatives useful as antagonists of the motilin receptor |
Country Status (4)
Country | Link |
---|---|
US (2) | US6384031B2 (en) |
AR (1) | AR029897A1 (en) |
AU (1) | AU2001247357A1 (en) |
WO (1) | WO2001068622A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002016404A1 (en) * | 2000-08-24 | 2002-02-28 | Chugai Seiyaku Kabushiki Kaisha | Cyclic peptide derivative |
ES2338789T3 (en) | 2003-06-18 | 2010-05-12 | Tranzyme Pharma Inc. | MACROCICLIC ANTAGONISTS OF THE MOTILINA RECEPTOR. |
GB0611907D0 (en) | 2006-06-15 | 2006-07-26 | Glaxo Group Ltd | Compounds |
JP2009501199A (en) | 2005-07-12 | 2009-01-15 | グラクソ グループ リミテッド | Piperazine heteroaryl derivatives as GPR38 agonists |
BRPI0613987A2 (en) | 2005-07-26 | 2011-03-01 | Glaxo Group Ltd | benzylpiperazine derivatives and their medical use |
WO2008000729A1 (en) * | 2006-06-28 | 2008-01-03 | Glaxo Group Limited | Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases |
WO2008033328A2 (en) | 2006-09-11 | 2008-03-20 | Tranzyme Pharma, Inc. | Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders |
US20080287371A1 (en) * | 2007-05-17 | 2008-11-20 | Tranzyme Pharma Inc. | Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex |
US8697877B2 (en) | 2009-02-27 | 2014-04-15 | Raqualia Pharma Inc. | Oxyindole derivatives with motilin receptor agonistic activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2636628B1 (en) | 1988-08-25 | 1990-12-28 | Sanofi Sa | THIADIAZOLE-1,3,4 DERIVATIVES, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
PT777659E (en) | 1994-08-15 | 2001-09-28 | Merck Sharp & Dohme | MORPHINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS |
US5972939A (en) | 1997-10-28 | 1999-10-26 | Ortho-Mcneil Pharmaceutical, Inc. | Cyclopentene derivatives useful as antagonists of the motilin receptor |
-
2001
- 2001-03-09 US US09/803,565 patent/US6384031B2/en not_active Expired - Lifetime
- 2001-03-09 AU AU2001247357A patent/AU2001247357A1/en not_active Abandoned
- 2001-03-09 WO PCT/US2001/007704 patent/WO2001068622A1/en active Application Filing
- 2001-03-13 AR ARP010101168A patent/AR029897A1/en unknown
-
2002
- 2002-03-12 US US10/095,981 patent/US6667309B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AR029897A1 (en) | 2003-07-23 |
US20010056106A1 (en) | 2001-12-27 |
US6667309B2 (en) | 2003-12-23 |
WO2001068622A1 (en) | 2001-09-20 |
US20020103238A1 (en) | 2002-08-01 |
US6384031B2 (en) | 2002-05-07 |
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