IL145046A0 - Use of casb616 polypeptides and polynucleotides for cancer treatment - Google Patents
Use of casb616 polypeptides and polynucleotides for cancer treatmentInfo
- Publication number
- IL145046A0 IL145046A0 IL14504600A IL14504600A IL145046A0 IL 145046 A0 IL145046 A0 IL 145046A0 IL 14504600 A IL14504600 A IL 14504600A IL 14504600 A IL14504600 A IL 14504600A IL 145046 A0 IL145046 A0 IL 145046A0
- Authority
- IL
- Israel
- Prior art keywords
- polynucleotides
- cancer treatment
- casb616
- polypeptides
- casb616 polypeptides
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/82—Colon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Catalysts (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9905124.5A GB9905124D0 (en) | 1999-03-05 | 1999-03-05 | Novel compounds |
PCT/EP2000/001587 WO2000053216A2 (en) | 1999-03-05 | 2000-02-28 | Use of casb616 polypeptides and polynucleotides for cancer treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
IL145046A0 true IL145046A0 (en) | 2002-06-30 |
Family
ID=10849064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14504600A IL145046A0 (en) | 1999-03-05 | 2000-02-28 | Use of casb616 polypeptides and polynucleotides for cancer treatment |
Country Status (23)
Country | Link |
---|---|
US (1) | US20050129717A1 (cs) |
EP (2) | EP1162993B1 (cs) |
JP (1) | JP2002538218A (cs) |
KR (1) | KR20010102507A (cs) |
CN (1) | CN1374869A (cs) |
AT (1) | ATE292472T1 (cs) |
AU (1) | AU766789B2 (cs) |
BR (1) | BR0008784A (cs) |
CA (1) | CA2362370A1 (cs) |
CY (1) | CY1105585T1 (cs) |
CZ (1) | CZ20013189A3 (cs) |
DE (1) | DE60019273T2 (cs) |
ES (1) | ES2238026T3 (cs) |
GB (1) | GB9905124D0 (cs) |
HK (1) | HK1043729B (cs) |
HU (1) | HUP0200186A2 (cs) |
IL (1) | IL145046A0 (cs) |
NO (1) | NO20014292L (cs) |
NZ (1) | NZ513837A (cs) |
PL (1) | PL354143A1 (cs) |
PT (1) | PT1162993E (cs) |
TR (1) | TR200102577T2 (cs) |
WO (1) | WO2000053216A2 (cs) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001271621A1 (en) * | 2000-06-28 | 2002-01-08 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating colon cancer |
US20050019340A1 (en) * | 2000-10-18 | 2005-01-27 | Nathalie Garcon | Vaccines |
CN1446583A (zh) * | 2002-11-29 | 2003-10-08 | 帕弗瑞生物技术(北京)有限公司 | 一种肿瘤免疫治疗及预防性疫苗的组成、制备、应用方案 |
NZ583292A (en) | 2003-11-06 | 2012-03-30 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugation to ligands |
CN102973947A (zh) | 2004-06-01 | 2013-03-20 | 健泰科生物技术公司 | 抗体-药物偶联物和方法 |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
BRPI0516284A (pt) | 2004-09-23 | 2008-09-02 | Genentech Inc | anticorpo construìdo com cisteìna, método de selecionar anticorpos, compostos conjugados de droga-anticorpo, composição farmacêutica, método para matar ou inibir a proliferação de células de tumor, métodos de inibir a proliferação celular e o crescimento de células de tumor, artigo manufaturado e método para produzir um composto |
EP2475391B1 (en) | 2009-09-09 | 2018-09-12 | Centrose, LLC | Extracellular targeted drug conjugates |
EA024730B1 (ru) | 2010-04-15 | 2016-10-31 | Медимьюн Лимитед | Пирролбензодиазепиновые соединения, их конъюгаты, фармацевтические композиции, содержащие указанные конъюгаты, и применение указанных конъюгатов |
KR101839163B1 (ko) | 2010-06-08 | 2018-03-15 | 제넨테크, 인크. | 시스테인 조작된 항체 및 접합체 |
EP2640727B1 (en) | 2010-11-17 | 2015-05-13 | Genentech, Inc. | Alaninyl maytansinol antibody conjugates |
ES2567276T3 (es) | 2011-05-12 | 2016-04-21 | Genentech, Inc. | Método de LC-MS/MS de monitoreo de múltiples reacciones para detectar anticuerpos terapéuticos en muestras de animales usando péptidos de cambio de marco |
PT2750713E (pt) | 2011-10-14 | 2016-01-20 | Genentech Inc | Pirrolobenzodiazepinas e conjugados das mesmas |
WO2013130093A1 (en) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarkers for treatment with anti-tubulin chemotherapeutic compounds |
PT2906251T (pt) | 2012-10-12 | 2017-12-04 | Medimmune Ltd | Conjugados de pirrolobenzodiazepina-anticorpo anti-cd22 |
US10736903B2 (en) | 2012-10-12 | 2020-08-11 | Medimmune Limited | Pyrrolobenzodiazepine-anti-PSMA antibody conjugates |
JP5993093B2 (ja) | 2012-10-12 | 2016-09-14 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン類およびその複合体 |
MX364329B (es) | 2012-10-12 | 2019-04-23 | Medimmune Ltd | Conjugados del anticuerpo pirrolobenzodiazepina. |
WO2014057120A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-antibody conjugates |
SI2906296T1 (en) | 2012-10-12 | 2018-06-29 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
MX364326B (es) | 2012-10-12 | 2019-04-23 | Medimmune Ltd | Conjugados del anticuerpo pirrolobenzodiazepina - anti-psma. |
US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
EA031585B1 (ru) | 2012-12-21 | 2019-01-31 | Медимьюн Лимитед | Пирролобензодиазепины и их конъюгаты |
CA2904044C (en) | 2013-03-13 | 2020-03-31 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
SG11201507214SA (en) | 2013-03-13 | 2015-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
NZ712035A (en) | 2013-03-13 | 2019-06-28 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
KR20160042080A (ko) | 2013-08-12 | 2016-04-18 | 제넨테크, 인크. | 1-(클로로메틸)-2,3-디히드로-1H-벤조[e]인돌 이량체 항체-약물 접합체 화합물, 및 사용 및 치료 방법 |
EP3054985B1 (en) | 2013-10-11 | 2018-12-26 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
US10010624B2 (en) | 2013-10-11 | 2018-07-03 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
US9956299B2 (en) | 2013-10-11 | 2018-05-01 | Medimmune Limited | Pyrrolobenzodiazepine—antibody conjugates |
PE20161394A1 (es) | 2013-12-16 | 2017-01-06 | Genentech Inc | Compuestos peptidomimeticos y sus conjugados de anticuerpo-farmaco |
EP3082874A2 (en) | 2013-12-16 | 2016-10-26 | Genentech, Inc. | Peptidomimetic compounds and antibody-drug conjugates thereof |
WO2015095212A1 (en) | 2013-12-16 | 2015-06-25 | Genentech, Inc. | 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment |
WO2016037644A1 (en) | 2014-09-10 | 2016-03-17 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
CN107108724A (zh) | 2014-09-12 | 2017-08-29 | 豪夫迈·罗氏有限公司 | 半胱氨酸改造抗体和缀合物 |
EP3191134B1 (en) | 2014-09-12 | 2019-11-20 | Genentech, Inc. | Anthracycline disulfide intermediates, antibody-drug conjugates and methods |
GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
US20160074527A1 (en) | 2014-09-17 | 2016-03-17 | Genentech, Inc. | Pyrrolobenzodiazepines and antibody disulfide conjugates thereof |
CA2968447A1 (en) | 2014-11-25 | 2016-06-02 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates and their use to treat neoplasms |
WO2016090050A1 (en) | 2014-12-03 | 2016-06-09 | Genentech, Inc. | Quaternary amine compounds and antibody-drug conjugates thereof |
GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
JP6943872B2 (ja) | 2016-03-25 | 2021-10-06 | ジェネンテック, インコーポレイテッド | 多重全抗体及び抗体複合体化薬物定量化アッセイ |
GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
CN109152843A (zh) | 2016-05-20 | 2019-01-04 | 豪夫迈·罗氏有限公司 | Protac抗体缀合物及其使用方法 |
WO2017205741A1 (en) | 2016-05-27 | 2017-11-30 | Genentech, Inc. | Bioanalytical method for the characterization of site-specific antibody-drug conjugates |
EP3464280B1 (en) | 2016-06-06 | 2021-10-06 | F. Hoffmann-La Roche AG | Silvestrol antibody-drug conjugates and methods of use |
WO2018031662A1 (en) | 2016-08-11 | 2018-02-15 | Genentech, Inc. | Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof |
EP3522933B1 (en) | 2016-10-05 | 2021-12-15 | F. Hoffmann-La Roche AG | Methods for preparing antibody drug conjugates |
GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
DK3544636T3 (da) | 2017-02-08 | 2021-05-10 | Adc Therapeutics Sa | Pyrrolobenzodiazepin-antistof-konjugater |
RS63502B1 (sr) | 2017-04-18 | 2022-09-30 | Medimmune Ltd | Konjugati pirolobenzodiazepina |
CA3057748A1 (en) | 2017-04-20 | 2018-10-25 | Adc Therapeutics Sa | Combination therapy with an anti-axl antibody-drug conjugate |
UA127900C2 (uk) | 2017-06-14 | 2024-02-07 | Ейдісі Терапьютікс Са | Схема дозування для введення adc до cd19 |
WO2019034764A1 (en) | 2017-08-18 | 2019-02-21 | Medimmune Limited | CONJUGATES OF PYRROLOBENZODIAZEPINE |
US10301319B2 (en) | 2017-09-20 | 2019-05-28 | Ph Pharma Co., Ltd. | Thailanstatin analogs |
US11068545B2 (en) | 2017-11-17 | 2021-07-20 | Battelle Memorial Institute | Spatial identification of assets using n-dimensional asset identifiers |
GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
JP2022505450A (ja) | 2018-10-24 | 2022-01-14 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | コンジュゲート化された化学的分解誘導物質および使用方法 |
CN113227119A (zh) | 2018-12-10 | 2021-08-06 | 基因泰克公司 | 用于与含Fc的蛋白质进行位点特异性缀合的光交联肽 |
GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU766077C (en) * | 1998-11-20 | 2004-10-07 | Genentech Inc. | Uses for Eph receptor antagonists and agonists to treat vascular disorders |
-
1999
- 1999-03-05 GB GBGB9905124.5A patent/GB9905124D0/en not_active Ceased
-
2000
- 2000-02-28 ES ES00907633T patent/ES2238026T3/es not_active Expired - Lifetime
- 2000-02-28 CN CN00807172A patent/CN1374869A/zh active Pending
- 2000-02-28 PL PL00354143A patent/PL354143A1/xx not_active Application Discontinuation
- 2000-02-28 DE DE60019273T patent/DE60019273T2/de not_active Expired - Fee Related
- 2000-02-28 TR TR2001/02577T patent/TR200102577T2/xx unknown
- 2000-02-28 HU HU0200186A patent/HUP0200186A2/hu unknown
- 2000-02-28 CZ CZ20013189A patent/CZ20013189A3/cs unknown
- 2000-02-28 CA CA002362370A patent/CA2362370A1/en not_active Abandoned
- 2000-02-28 BR BR0008784-0A patent/BR0008784A/pt not_active IP Right Cessation
- 2000-02-28 AU AU29153/00A patent/AU766789B2/en not_active Ceased
- 2000-02-28 WO PCT/EP2000/001587 patent/WO2000053216A2/en not_active Application Discontinuation
- 2000-02-28 AT AT00907633T patent/ATE292472T1/de not_active IP Right Cessation
- 2000-02-28 EP EP00907633A patent/EP1162993B1/en not_active Expired - Lifetime
- 2000-02-28 NZ NZ513837A patent/NZ513837A/xx unknown
- 2000-02-28 KR KR1020017011300A patent/KR20010102507A/ko not_active Application Discontinuation
- 2000-02-28 PT PT00907633T patent/PT1162993E/pt unknown
- 2000-02-28 EP EP04076929A patent/EP1466616A3/en not_active Withdrawn
- 2000-02-28 JP JP2000603705A patent/JP2002538218A/ja active Pending
- 2000-02-28 IL IL14504600A patent/IL145046A0/xx unknown
-
2001
- 2001-09-04 NO NO20014292A patent/NO20014292L/no not_active Application Discontinuation
-
2002
- 2002-05-21 HK HK02103796.8A patent/HK1043729B/zh not_active IP Right Cessation
-
2004
- 2004-11-09 US US10/984,521 patent/US20050129717A1/en not_active Abandoned
-
2005
- 2005-05-18 CY CY20051100614T patent/CY1105585T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU2915300A (en) | 2000-09-28 |
HK1043729B (zh) | 2005-11-04 |
EP1466616A2 (en) | 2004-10-13 |
DE60019273T2 (de) | 2006-01-19 |
TR200102577T2 (tr) | 2004-09-21 |
NO20014292L (no) | 2001-10-29 |
CZ20013189A3 (cs) | 2002-02-13 |
EP1466616A3 (en) | 2004-12-01 |
AU766789B2 (en) | 2003-10-23 |
ES2238026T3 (es) | 2005-08-16 |
CA2362370A1 (en) | 2000-09-14 |
US20050129717A1 (en) | 2005-06-16 |
CN1374869A (zh) | 2002-10-16 |
HK1043729A1 (en) | 2002-09-27 |
GB9905124D0 (en) | 1999-04-28 |
NO20014292D0 (no) | 2001-09-04 |
PT1162993E (pt) | 2005-06-30 |
BR0008784A (pt) | 2001-12-26 |
JP2002538218A (ja) | 2002-11-12 |
CY1105585T1 (el) | 2010-07-28 |
NZ513837A (en) | 2003-02-28 |
PL354143A1 (en) | 2003-12-29 |
WO2000053216A3 (en) | 2001-01-11 |
EP1162993B1 (en) | 2005-04-06 |
DE60019273D1 (de) | 2005-05-12 |
ATE292472T1 (de) | 2005-04-15 |
EP1162993A2 (en) | 2001-12-19 |
KR20010102507A (ko) | 2001-11-15 |
WO2000053216A2 (en) | 2000-09-14 |
HUP0200186A2 (en) | 2002-05-29 |
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