IL144405A0 - Process for producing hmg-coa reductase inhibitors - Google Patents

Process for producing hmg-coa reductase inhibitors

Info

Publication number
IL144405A0
IL144405A0 IL14440500A IL14440500A IL144405A0 IL 144405 A0 IL144405 A0 IL 144405A0 IL 14440500 A IL14440500 A IL 14440500A IL 14440500 A IL14440500 A IL 14440500A IL 144405 A0 IL144405 A0 IL 144405A0
Authority
IL
Israel
Prior art keywords
compound
substituted
coa reductase
reductase inhibitors
culture
Prior art date
Application number
IL14440500A
Other languages
English (en)
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of IL144405A0 publication Critical patent/IL144405A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL14440500A 1999-01-20 2000-01-20 Process for producing hmg-coa reductase inhibitors IL144405A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1239299 1999-01-20
PCT/JP2000/000245 WO2000043533A1 (fr) 1999-01-20 2000-01-20 Procede de production d'inhibiteurs de la hmg coa-reducatase

Publications (1)

Publication Number Publication Date
IL144405A0 true IL144405A0 (en) 2002-05-23

Family

ID=11804010

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14440500A IL144405A0 (en) 1999-01-20 2000-01-20 Process for producing hmg-coa reductase inhibitors

Country Status (14)

Country Link
US (1) US6946270B1 (ja)
EP (1) EP1146126B1 (ja)
JP (1) JP4428866B2 (ja)
KR (1) KR100633867B1 (ja)
CN (1) CN1240844C (ja)
AT (1) ATE360703T1 (ja)
AU (1) AU3074300A (ja)
CA (1) CA2358927A1 (ja)
CZ (1) CZ20012622A3 (ja)
DE (1) DE60034547T8 (ja)
HK (1) HK1040419B (ja)
HU (1) HUP0105000A3 (ja)
IL (1) IL144405A0 (ja)
WO (1) WO2000043533A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329508C (zh) * 1999-01-29 2007-08-01 协和发酵工业株式会社 HMG－CoA还原酶抑制剂的制备方法
CN101351551A (zh) * 2005-11-29 2009-01-21 协和发酵工业株式会社 新型蛋白质和编码该蛋白质的dna
JP2010512733A (ja) * 2006-12-13 2010-04-30 ディーエスエム アイピー アセッツ ビー．ブイ． プラバスタチンを調製するための方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750894A (en) 1980-09-08 1982-03-25 Sankyo Co Ltd Preparation of ml-236b derivative
MX7065E (es) 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b
JPS5889191A (ja) * 1981-11-20 1983-05-27 Sankyo Co Ltd ３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
JP2672551B2 (ja) 1987-03-02 1997-11-05 三共株式会社 チトクロームｐ−４５０遺伝子を含有するｄｎａ
US6043064A (en) 1993-10-22 2000-03-28 Bristol-Myers Squibb Company Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
US5942423A (en) 1995-06-07 1999-08-24 Massachusetts Institute Of Technology Conversion of compactin to pravastatin by actinomadura
KR100433888B1 (ko) 1997-08-07 2004-06-04 교와 핫꼬 고교 가부시끼가이샤 ＨＭＧ-ＣｏＡ 환원효소 저해제의 제조법
WO1999010499A1 (en) 1997-08-22 1999-03-04 Dsm N.V. Statin production by fermentation
SI9800144A (sl) * 1998-05-21 1999-12-31 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Nov biotehnološki postopek pridobivanja 3-hidroksi-ML-236B derivatov poznanih kot M-4 in M-4'
CN1329508C (zh) 1999-01-29 2007-08-01 协和发酵工业株式会社 HMG－CoA还原酶抑制剂的制备方法

Also Published As

Publication number Publication date
DE60034547T8 (de) 2008-04-30
CA2358927A1 (en) 2000-07-27
HUP0105000A3 (en) 2004-03-01
EP1146126A1 (en) 2001-10-17
WO2000043533A1 (fr) 2000-07-27
CN1240844C (zh) 2006-02-08
KR100633867B1 (ko) 2006-10-16
JP4428866B2 (ja) 2010-03-10
CN1344328A (zh) 2002-04-10
EP1146126B1 (en) 2007-04-25
EP1146126A4 (en) 2004-05-19
AU3074300A (en) 2000-08-07
ATE360703T1 (de) 2007-05-15
US6946270B1 (en) 2005-09-20
KR20020002375A (ko) 2002-01-09
HUP0105000A2 (hu) 2002-04-29
DE60034547D1 (de) 2007-06-06
HK1040419A1 (en) 2002-06-07
CZ20012622A3 (cs) 2002-01-16
DE60034547T2 (de) 2008-01-10
HK1040419B (zh) 2007-12-14

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