IL144405A0 - Process for producing hmg-coa reductase inhibitors - Google Patents
Process for producing hmg-coa reductase inhibitorsInfo
- Publication number
- IL144405A0 IL144405A0 IL14440500A IL14440500A IL144405A0 IL 144405 A0 IL144405 A0 IL 144405A0 IL 14440500 A IL14440500 A IL 14440500A IL 14440500 A IL14440500 A IL 14440500A IL 144405 A0 IL144405 A0 IL 144405A0
- Authority
- IL
- Israel
- Prior art keywords
- compound
- substituted
- coa reductase
- reductase inhibitors
- culture
- Prior art date
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000028644 hyphal growth Effects 0.000 abstract 1
- 125000000686 lactone group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1239299 | 1999-01-20 | ||
| PCT/JP2000/000245 WO2000043533A1 (fr) | 1999-01-20 | 2000-01-20 | Procede de production d'inhibiteurs de la hmg coa-reducatase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL144405A0 true IL144405A0 (en) | 2002-05-23 |
Family
ID=11804010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14440500A IL144405A0 (en) | 1999-01-20 | 2000-01-20 | Process for producing hmg-coa reductase inhibitors |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6946270B1 (cs) |
| EP (1) | EP1146126B1 (cs) |
| JP (1) | JP4428866B2 (cs) |
| KR (1) | KR100633867B1 (cs) |
| CN (1) | CN1240844C (cs) |
| AT (1) | ATE360703T1 (cs) |
| AU (1) | AU3074300A (cs) |
| CA (1) | CA2358927A1 (cs) |
| CZ (1) | CZ20012622A3 (cs) |
| DE (1) | DE60034547T8 (cs) |
| HK (1) | HK1040419B (cs) |
| HU (1) | HUP0105000A3 (cs) |
| IL (1) | IL144405A0 (cs) |
| WO (1) | WO2000043533A1 (cs) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2360080A1 (en) | 1999-01-29 | 2000-08-03 | Kyowa Hakko Kogyo Co. Ltd. | Process for producing hmg-coa reductase inhibitor |
| CN101351551A (zh) | 2005-11-29 | 2009-01-21 | 协和发酵工业株式会社 | 新型蛋白质和编码该蛋白质的dna |
| US20100217032A1 (en) * | 2006-12-13 | 2010-08-26 | Paul Klaassen | Process for preparing pravastatin |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX7065E (es) | 1980-06-06 | 1987-04-10 | Sankyo Co | Un procedimiento microbiologico para preparar derivados de ml-236b |
| JPS5750894A (en) | 1980-09-08 | 1982-03-25 | Sankyo Co Ltd | Preparation of ml-236b derivative |
| JPS5889191A (ja) * | 1981-11-20 | 1983-05-27 | Sankyo Co Ltd | ３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法 |
| JP2672551B2 (ja) | 1987-03-02 | 1997-11-05 | 三共株式会社 | チトクロームｐ−４５０遺伝子を含有するｄｎａ |
| US6043064A (en) * | 1993-10-22 | 2000-03-28 | Bristol-Myers Squibb Company | Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof |
| US5942423A (en) | 1995-06-07 | 1999-08-24 | Massachusetts Institute Of Technology | Conversion of compactin to pravastatin by actinomadura |
| ATE389026T1 (de) | 1997-08-07 | 2008-03-15 | Kyowa Hakko Kogyo Kk | Verfahren für die herstellung von inhibitoren der hmg-coa-reduktase. |
| EP1015600A1 (en) | 1997-08-22 | 2000-07-05 | Dsm N.V. | Statin production by fermentation |
| SI9800144A (sl) * | 1998-05-21 | 1999-12-31 | LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. | Nov biotehnološki postopek pridobivanja 3-hidroksi-ML-236B derivatov poznanih kot M-4 in M-4' |
| CA2360080A1 (en) | 1999-01-29 | 2000-08-03 | Kyowa Hakko Kogyo Co. Ltd. | Process for producing hmg-coa reductase inhibitor |
-
2000
- 2000-01-20 IL IL14440500A patent/IL144405A0/xx unknown
- 2000-01-20 HU HU0105000A patent/HUP0105000A3/hu not_active Application Discontinuation
- 2000-01-20 DE DE60034547T patent/DE60034547T8/de active Active
- 2000-01-20 EP EP00900832A patent/EP1146126B1/en not_active Expired - Lifetime
- 2000-01-20 KR KR1020017009115A patent/KR100633867B1/ko not_active Expired - Fee Related
- 2000-01-20 JP JP2000594941A patent/JP4428866B2/ja not_active Expired - Lifetime
- 2000-01-20 CN CNB008052123A patent/CN1240844C/zh not_active Expired - Fee Related
- 2000-01-20 CZ CZ20012622A patent/CZ20012622A3/cs unknown
- 2000-01-20 AT AT00900832T patent/ATE360703T1/de not_active IP Right Cessation
- 2000-01-20 WO PCT/JP2000/000245 patent/WO2000043533A1/ja active Search and Examination
- 2000-01-20 US US09/868,924 patent/US6946270B1/en not_active Expired - Fee Related
- 2000-01-20 CA CA002358927A patent/CA2358927A1/en not_active Abandoned
- 2000-01-20 AU AU30743/00A patent/AU3074300A/en not_active Abandoned
- 2000-01-20 HK HK02101719.6A patent/HK1040419B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60034547T2 (de) | 2008-01-10 |
| KR100633867B1 (ko) | 2006-10-16 |
| CA2358927A1 (en) | 2000-07-27 |
| DE60034547D1 (de) | 2007-06-06 |
| ATE360703T1 (de) | 2007-05-15 |
| HK1040419B (en) | 2007-12-14 |
| KR20020002375A (ko) | 2002-01-09 |
| US6946270B1 (en) | 2005-09-20 |
| HUP0105000A2 (hu) | 2002-04-29 |
| EP1146126A1 (en) | 2001-10-17 |
| EP1146126B1 (en) | 2007-04-25 |
| CN1240844C (zh) | 2006-02-08 |
| HUP0105000A3 (en) | 2004-03-01 |
| WO2000043533A1 (fr) | 2000-07-27 |
| AU3074300A (en) | 2000-08-07 |
| EP1146126A4 (en) | 2004-05-19 |
| CN1344328A (zh) | 2002-04-10 |
| CZ20012622A3 (cs) | 2002-01-16 |
| JP4428866B2 (ja) | 2010-03-10 |
| DE60034547T8 (de) | 2008-04-30 |
| HK1040419A1 (en) | 2002-06-07 |
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