IL144032A0 - Serine protease inhibitors - Google Patents
Serine protease inhibitorsInfo
- Publication number
- IL144032A0 IL144032A0 IL14403200A IL14403200A IL144032A0 IL 144032 A0 IL144032 A0 IL 144032A0 IL 14403200 A IL14403200 A IL 14403200A IL 14403200 A IL14403200 A IL 14403200A IL 144032 A0 IL144032 A0 IL 144032A0
- Authority
- IL
- Israel
- Prior art keywords
- serine protease
- protease inhibitors
- compounds
- factor
- kallikrein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/05—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/18—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/51—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11577299P | 1999-01-13 | 1999-01-13 | |
US15202999P | 1999-09-01 | 1999-09-01 | |
PCT/US2000/000673 WO2000041531A2 (en) | 1999-01-13 | 2000-01-11 | Serine protease inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IL144032A0 true IL144032A0 (en) | 2002-04-21 |
Family
ID=26813550
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14403200A IL144032A0 (en) | 1999-01-13 | 2000-01-11 | Serine protease inhibitors |
IL144032A IL144032A (en) | 1999-01-13 | 2001-06-27 | Serine protease inhibitors |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL144032A IL144032A (en) | 1999-01-13 | 2001-06-27 | Serine protease inhibitors |
Country Status (19)
Country | Link |
---|---|
US (4) | US6472393B1 (zh) |
EP (1) | EP1144373B1 (zh) |
JP (1) | JP2002534449A (zh) |
KR (1) | KR100838418B1 (zh) |
CN (1) | CN100488947C (zh) |
AT (1) | ATE307111T1 (zh) |
AU (1) | AU771776B2 (zh) |
BR (1) | BR0008755A (zh) |
CA (1) | CA2356934A1 (zh) |
CZ (1) | CZ20012508A3 (zh) |
DE (1) | DE60023266T2 (zh) |
ES (1) | ES2251363T3 (zh) |
HU (1) | HUP0105077A3 (zh) |
IL (2) | IL144032A0 (zh) |
MX (1) | MXPA01007038A (zh) |
NO (1) | NO20013462L (zh) |
NZ (1) | NZ512736A (zh) |
PL (1) | PL350042A1 (zh) |
WO (1) | WO2000041531A2 (zh) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60023266T2 (de) * | 1999-01-13 | 2006-07-13 | Genentech Inc., San Francisco | Serinprotease-inhibitoren |
AU7447500A (en) * | 1999-09-30 | 2001-04-30 | Mitsubishi Chemical Corporation | Acylsulfonamide derivatives |
MXPA03009130A (es) | 2000-10-20 | 2004-02-26 | Biocryst Pharm Inc | Compuestos de biarilo que funcionan como inhibidores de proteasa serina. |
JP4179878B2 (ja) | 2001-02-02 | 2008-11-12 | 中外製薬株式会社 | ペプチド誘導体 |
DE10130374A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Substituierte N-Acyl-anilinderivate, deren Herstellung und deren Verwendung als Arzneimittel |
JP4898091B2 (ja) * | 2002-03-11 | 2012-03-14 | ザ メディシンズ カンパニー (ライプツィヒ) ゲーエムベーハー | ウロキナーゼの阻害剤、それらの製造および使用 |
GB0207637D0 (en) * | 2002-04-02 | 2002-05-15 | Karobio Ab | Novel compound |
WO2003101941A2 (en) * | 2002-05-31 | 2003-12-11 | Genzyme Corporation | Alpha acyloxyacetamides for kallikrein and urokinase inhibition |
DE10301300B4 (de) | 2003-01-15 | 2009-07-16 | Curacyte Chemistry Gmbh | Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein |
EP1594505A4 (en) * | 2003-02-11 | 2008-08-13 | Bristol Myers Squibb Co | PHENYLGLYCIN DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS |
JP2006517589A (ja) * | 2003-02-11 | 2006-07-27 | ブリストル−マイヤーズ スクイブ カンパニー | セリンプロテアーゼ・インヒビターとして有用なベンゼンアセトアミド化合物 |
JP2007505160A (ja) * | 2003-05-20 | 2007-03-08 | ジェネンテック・インコーポレーテッド | 第VIIa因子のアシルスルファミド阻害剤 |
WO2004113316A1 (en) * | 2003-05-20 | 2004-12-29 | Genentech, Inc. | Benzofuran inhibitors of factor viia |
DE10342108A1 (de) * | 2003-09-11 | 2005-04-14 | Curacyte Chemistry Gmbh | Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung |
ATE479676T1 (de) * | 2005-01-10 | 2010-09-15 | Bristol Myers Squibb Co | Als antikoagulanzien verwendbare phenylglycinamid-derivate |
US7514410B2 (en) | 2005-03-29 | 2009-04-07 | Biocryst Pharmaceuticals, Inc. | Hepatitis C therapies |
AU2006202083A1 (en) * | 2005-06-03 | 2006-12-21 | Reto Brun | Linear dicationic terphenyls and their aza analogues as antiparasitic agents |
US7964619B2 (en) | 2005-06-03 | 2011-06-21 | The University Of North Carolina At Chapel Hill | Teraryl components as antiparasitic agents |
DE602006011752D1 (de) * | 2005-06-24 | 2010-03-04 | Bristol Myers Squibb Co | Als antikoagulationsmittel geeignete phenylglycinamid- und pyridylglycinamidderivate |
US7816522B2 (en) | 2006-03-24 | 2010-10-19 | Eisai Co., Ltd. | Triazolone derivatives |
US7776832B2 (en) | 2006-04-21 | 2010-08-17 | Gem Pharmaceuticals, Llc | Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines |
DE102006050672A1 (de) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | Hemmstoffe des Plasmins und des Plasmakallikreins |
TW200831080A (en) * | 2006-12-15 | 2008-08-01 | Irm Llc | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity |
SG177974A1 (en) | 2007-01-12 | 2012-02-28 | Biocryst Pharm Inc | Antiviral nucleoside analogs |
NZ608343A (en) | 2007-04-13 | 2014-09-26 | Southern Res Inst | Anti-angiogenic agents and methods of use |
JP2010535240A (ja) * | 2007-07-31 | 2010-11-18 | マリンクロッド・インコーポレイテッド | 一体化光活性薬剤およびその使用 |
WO2009038157A1 (ja) | 2007-09-21 | 2009-03-26 | Eisai R & D Management Co., Ltd. | 2,3-ジヒドロ-イミノイソインドール誘導体 |
TW200942243A (en) | 2008-03-05 | 2009-10-16 | Biocryst Pharm Inc | Antiviral therapeutic agents |
WO2010036407A2 (en) | 2008-05-15 | 2010-04-01 | Biocryst Pharmaceuticals, Inc. | Antiviral nucleoside analogs |
CA2753282C (en) | 2009-03-10 | 2017-11-28 | Med Discovery Sa | Use of serine protease inhibitors in the treatment of neutropenia |
TW201206905A (en) | 2010-05-20 | 2012-02-16 | Eisai R & Amp D Man Co Ltd | Prodrug of triazolone compound |
EP2590945B1 (en) | 2010-07-07 | 2014-04-30 | The Medicines Company (Leipzig) GmbH | Serine protease inhibitors |
WO2013166276A1 (en) | 2012-05-02 | 2013-11-07 | Southern Research Institute | Triazolopyridazine compounds, use as inhibitors of the kinase lrrk2, and methods for preparation thereof |
US10167286B2 (en) | 2014-02-11 | 2019-01-01 | Mitokinin, Inc. | Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease |
CN108934162A (zh) | 2015-12-16 | 2018-12-04 | 南方研究所 | 吡咯并嘧啶化合物、作为激酶lrrk2抑制剂的用途及其制备方法 |
US11001586B2 (en) | 2016-11-17 | 2021-05-11 | The University Of North Carolina At Chapel Hill | Alkyl pyrrolopyrimidine analogs and methods of making and using same |
US10450263B2 (en) | 2017-02-10 | 2019-10-22 | Southern Research Institute | Benzo annulenes as antiviral agents |
US11160826B1 (en) | 2017-03-03 | 2021-11-02 | United States Government As Represented By The Department Of Veterans Affairs | Cholesterol lowering drugs for the treatment of hepatic encephalopathy |
KR20200019228A (ko) | 2017-06-21 | 2020-02-21 | 미토키닌, 인크. | 신경퇴행성 및 미토콘드리아 질환의 치료를 위한 조성물 및 이를 사용하는 방법 |
US11046729B2 (en) | 2017-10-26 | 2021-06-29 | Southern Research Institute | Dipeptide analogs as TGF-beta inhibitors |
EP3551188B1 (en) | 2017-10-31 | 2023-10-18 | Southern Research Institute | Substituted quinazoline sulfonamides as thioredoxin interacting protein (txnip) inhibitors |
TW202010742A (zh) | 2018-04-06 | 2020-03-16 | 美商百歐克斯製藥公司 | 取代的苯并呋喃、苯并吡咯、苯并噻吩及結構相關的補體抑制劑 |
EP4209498A1 (en) | 2018-04-19 | 2023-07-12 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
CA3115075A1 (en) | 2018-10-02 | 2020-04-09 | The United States Government As Represented By The Department Of Veterans Affairs | Spak kinase inhibitors as neuroprotective agents |
CN114502174A (zh) | 2019-06-14 | 2022-05-13 | 南方研究院 | 2,4,7取代的-7-脱氮-2′-脱氧-2′-氟阿拉伯糖基核苷和核苷酸前药及其用途 |
EP4125845A4 (en) | 2020-04-02 | 2024-05-15 | Southern Research Institute | NEW ANALOGS OF 2-PYRIMIDONE USED AS POWERFUL ANTIVIRAL AGENTS AGAINST ALPHAVIRUS |
CA3199427A1 (en) | 2020-11-18 | 2022-05-27 | Mark J. Suto | Compounds for the treatment of acute and chronic kidney disease |
US11753374B2 (en) | 2020-11-18 | 2023-09-12 | Southern Reserach Institute | Compounds for the treatment of acute and chronic kidney disease |
US11905306B2 (en) | 2021-12-21 | 2024-02-20 | Southern Research Institute | Substituted phenyl ethynyl pyridine carboxamides as potent inhibitors of SARS virus |
WO2023147352A1 (en) | 2022-01-27 | 2023-08-03 | Trilink Biotechnologies, Llc | Trinucleotide cap analogs and methods of use thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA928276B (en) | 1991-10-31 | 1993-05-06 | Daiichi Seiyaku Co | Aromatic amidine derivates and salts thereof. |
DE4342154A1 (de) | 1993-12-10 | 1995-06-14 | Behringwerke Ag | Amidinophenylalaninderivate, Verfahren zu deren Herstellung, deren Verwendung und diese enthaltende Mittel als Antikoagulantien |
WO1996016940A1 (fr) | 1994-12-02 | 1996-06-06 | Yamanouchi Pharmaceutical Co., Ltd. | Nouveau derive d'amidinonaphtyle ou sel de celui-ci |
ATE251141T1 (de) * | 1995-03-10 | 2003-10-15 | Berlex Lab | Benzamidin-derivate, deren herstellung und deren verwendung als anti-koagulantien |
US5863929A (en) * | 1996-06-25 | 1999-01-26 | Eli Lilly And Company | Anticoagulant agents |
US6020357A (en) * | 1996-12-23 | 2000-02-01 | Dupont Pharmaceuticals Company | Nitrogen containing heteroaromatics as factor Xa inhibitors |
TW542822B (en) * | 1997-01-17 | 2003-07-21 | Ajinomoto Kk | Benzamidine derivatives |
EP0975625A1 (en) * | 1997-04-14 | 2000-02-02 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
CA2285659A1 (en) * | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | Selective factor xa inhibitors |
WO1998046626A1 (en) * | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
JP2001521524A (ja) * | 1997-04-14 | 2001-11-06 | シーオーアール セラピューティクス インコーポレイテッド | 選択的Xa因子阻害剤 |
DE19718181A1 (de) * | 1997-04-30 | 1998-11-05 | Boehringer Ingelheim Pharma | Disubstituierte bicyclische Heterocyclen, ihre Herstellung und ihre Verwendung als Arzneimittel |
US5998424A (en) * | 1997-06-19 | 1999-12-07 | Dupont Pharmaceuticals Company | Inhibitors of factor Xa with a neutral P1 specificity group |
EP0987274A1 (en) * | 1998-09-15 | 2000-03-22 | Hoechst Marion Roussel Deutschland GmbH | Factor VIIa Inhibitors |
DE60023266T2 (de) * | 1999-01-13 | 2006-07-13 | Genentech Inc., San Francisco | Serinprotease-inhibitoren |
-
2000
- 2000-01-11 DE DE60023266T patent/DE60023266T2/de not_active Expired - Lifetime
- 2000-01-11 KR KR1020017008804A patent/KR100838418B1/ko not_active IP Right Cessation
- 2000-01-11 ES ES00911572T patent/ES2251363T3/es not_active Expired - Lifetime
- 2000-01-11 CN CNB008044228A patent/CN100488947C/zh not_active Expired - Fee Related
- 2000-01-11 NZ NZ512736A patent/NZ512736A/en not_active IP Right Cessation
- 2000-01-11 JP JP2000593153A patent/JP2002534449A/ja active Pending
- 2000-01-11 CZ CZ20012508A patent/CZ20012508A3/cs unknown
- 2000-01-11 AU AU33451/00A patent/AU771776B2/en not_active Ceased
- 2000-01-11 CA CA002356934A patent/CA2356934A1/en not_active Abandoned
- 2000-01-11 WO PCT/US2000/000673 patent/WO2000041531A2/en active IP Right Grant
- 2000-01-11 MX MXPA01007038A patent/MXPA01007038A/es active IP Right Grant
- 2000-01-11 AT AT00911572T patent/ATE307111T1/de not_active IP Right Cessation
- 2000-01-11 BR BRPI0008755-6A patent/BR0008755A/pt not_active Application Discontinuation
- 2000-01-11 PL PL00350042A patent/PL350042A1/xx not_active Application Discontinuation
- 2000-01-11 HU HU0105077A patent/HUP0105077A3/hu not_active Application Discontinuation
- 2000-01-11 EP EP00911572A patent/EP1144373B1/en not_active Expired - Lifetime
- 2000-01-11 US US09/509,104 patent/US6472393B1/en not_active Expired - Fee Related
- 2000-01-11 IL IL14403200A patent/IL144032A0/xx active IP Right Grant
-
2001
- 2001-06-27 IL IL144032A patent/IL144032A/en not_active IP Right Cessation
- 2001-07-12 NO NO20013462A patent/NO20013462L/no not_active Application Discontinuation
-
2002
- 2002-08-19 US US10/224,114 patent/US6919369B2/en not_active Expired - Fee Related
-
2005
- 2005-03-24 US US11/088,511 patent/US20050186198A1/en not_active Abandoned
-
2006
- 2006-09-29 US US11/537,482 patent/US20070037813A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60023266D1 (de) | 2005-11-24 |
ES2251363T3 (es) | 2006-05-01 |
WO2000041531A3 (en) | 2001-08-16 |
KR20010101852A (ko) | 2001-11-15 |
WO2000041531A2 (en) | 2000-07-20 |
US20050186198A1 (en) | 2005-08-25 |
US6472393B1 (en) | 2002-10-29 |
US6919369B2 (en) | 2005-07-19 |
US20070037813A1 (en) | 2007-02-15 |
AU771776B2 (en) | 2004-04-01 |
DE60023266T2 (de) | 2006-07-13 |
HUP0105077A3 (en) | 2005-04-28 |
EP1144373B1 (en) | 2005-10-19 |
IL144032A (en) | 2006-06-11 |
CN100488947C (zh) | 2009-05-20 |
NZ512736A (en) | 2003-11-28 |
EP1144373A2 (en) | 2001-10-17 |
NO20013462L (no) | 2001-09-12 |
NO20013462D0 (no) | 2001-07-12 |
US20030212071A1 (en) | 2003-11-13 |
PL350042A1 (en) | 2002-10-21 |
ATE307111T1 (de) | 2005-11-15 |
AU3345100A (en) | 2000-08-01 |
HUP0105077A2 (hu) | 2002-05-29 |
BR0008755A (pt) | 2007-05-29 |
CN1342139A (zh) | 2002-03-27 |
MXPA01007038A (es) | 2002-07-30 |
KR100838418B1 (ko) | 2008-06-13 |
CZ20012508A3 (cs) | 2002-02-13 |
EP1144373A3 (en) | 2002-01-02 |
CA2356934A1 (en) | 2000-07-20 |
JP2002534449A (ja) | 2002-10-15 |
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