IL142701A0 - Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors - Google Patents

Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors

Info

Publication number
IL142701A0
IL142701A0 IL14270199A IL14270199A IL142701A0 IL 142701 A0 IL142701 A0 IL 142701A0 IL 14270199 A IL14270199 A IL 14270199A IL 14270199 A IL14270199 A IL 14270199A IL 142701 A0 IL142701 A0 IL 142701A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
treating tumors
certain substituted
substituted caprolactams
Prior art date
Application number
IL14270199A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL142701A0 publication Critical patent/IL142701A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14270199A 1998-11-17 1999-11-15 Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors IL142701A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19335498A 1998-11-17 1998-11-17
PCT/EP1999/008767 WO2000029382A1 (en) 1998-11-17 1999-11-15 Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors

Publications (1)

Publication Number Publication Date
IL142701A0 true IL142701A0 (en) 2002-03-10

Family

ID=22713307

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14270199A IL142701A0 (en) 1998-11-17 1999-11-15 Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors

Country Status (25)

Country Link
EP (1) EP1131297B1 (de)
JP (1) JP3550545B2 (de)
KR (1) KR20010080461A (de)
CN (1) CN1187333C (de)
AR (1) AR023914A1 (de)
AT (1) ATE264309T1 (de)
AU (1) AU748016B2 (de)
BR (1) BR9915436A (de)
CA (1) CA2347773C (de)
CO (1) CO5140099A1 (de)
CZ (1) CZ20011707A3 (de)
DE (1) DE69916488T2 (de)
ES (1) ES2221463T3 (de)
HU (1) HUP0104224A3 (de)
ID (1) ID28343A (de)
IL (1) IL142701A0 (de)
NO (1) NO20012428L (de)
PE (1) PE20001241A1 (de)
PL (1) PL347633A1 (de)
PT (1) PT1131297E (de)
SK (1) SK6692001A3 (de)
TR (1) TR200101366T2 (de)
UY (2) UY25807A1 (de)
WO (1) WO2000029382A1 (de)
ZA (1) ZA200103419B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003532711A (ja) * 2000-05-11 2003-11-05 ノバルティス アクチエンゲゼルシャフト 置換カプロラクタム炭酸エステルおよびカプロラクタムエーテル、およびそれらの抗腫瘍薬としての使用
WO2002072555A1 (en) * 2001-03-12 2002-09-19 Novartis Ag Process for preparing certain substituted caprolactams
CN1856486A (zh) * 2003-07-25 2006-11-01 诺瓦提斯公司 取代的内酰胺和它们作为抗癌剂的用途
DE10349669B3 (de) * 2003-10-24 2005-05-25 Aventis Pharma Deutschland Gmbh Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US7153846B2 (en) 2003-10-24 2006-12-26 Sanofi-Aventis Deutschland Gmbh Bengamide derivatives, process for preparing them, and their use
FR2878525B1 (fr) 2004-11-29 2007-02-23 Aventis Pharma Sa Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2878528B1 (fr) 2004-11-29 2008-05-16 Aventis Pharma Sa 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2901555A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation
FR2901556A1 (fr) * 2006-05-24 2007-11-30 Sanofi Aventis Sa Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
FR2901554B1 (fr) 2006-05-24 2011-04-01 Sanofi Aventis 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation
EP2582680A1 (de) 2010-06-17 2013-04-24 Novartis AG Biphenyl-substituierte 1,3-dihydro-benzoimidazol-2-ylidenamidderivate
JP2013532149A (ja) 2010-06-17 2013-08-15 ノバルティス アーゲー ピペリジニル置換１，３−ジヒドロ−ベンゾイミダゾール−２−イリデンアミン誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9411841D0 (en) * 1994-06-14 1994-08-03 Pharma Mar Sa New antitumoral compounds from jaspis sponge

Also Published As

Publication number Publication date
PT1131297E (pt) 2004-08-31
BR9915436A (pt) 2001-08-07
CA2347773A1 (en) 2000-05-25
PL347633A1 (en) 2002-04-22
NO20012428L (no) 2001-07-17
CO5140099A1 (es) 2002-03-22
EP1131297B1 (de) 2004-04-14
DE69916488D1 (de) 2004-05-19
CZ20011707A3 (cs) 2001-08-15
PE20001241A1 (es) 2000-11-24
AU1506000A (en) 2000-06-05
CN1187333C (zh) 2005-02-02
AR023914A1 (es) 2002-09-04
NO20012428D0 (no) 2001-05-16
UY25807A1 (es) 2001-08-27
SK6692001A3 (en) 2001-10-08
JP2002529536A (ja) 2002-09-10
ES2221463T3 (es) 2004-12-16
JP3550545B2 (ja) 2004-08-04
WO2000029382A1 (en) 2000-05-25
KR20010080461A (ko) 2001-08-22
TR200101366T2 (tr) 2001-10-22
ATE264309T1 (de) 2004-04-15
ZA200103419B (en) 2002-06-26
ID28343A (id) 2001-05-17
DE69916488T2 (de) 2005-03-24
AU748016B2 (en) 2002-05-30
UY26036A1 (es) 2001-06-29
CN1326445A (zh) 2001-12-12
EP1131297A1 (de) 2001-09-12
HUP0104224A3 (en) 2002-04-29
CA2347773C (en) 2009-03-10
HUP0104224A2 (hu) 2002-03-28

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