ATE264309T1 - Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren - Google Patents

Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren

Info

Publication number
ATE264309T1
ATE264309T1 AT99957309T AT99957309T ATE264309T1 AT E264309 T1 ATE264309 T1 AT E264309T1 AT 99957309 T AT99957309 T AT 99957309T AT 99957309 T AT99957309 T AT 99957309T AT E264309 T1 ATE264309 T1 AT E264309T1
Authority
AT
Austria
Prior art keywords
tumors
treatment
pharmaceutical preparations
preparations containing
containing same
Prior art date
Application number
AT99957309T
Other languages
English (en)
Inventor
Frederick Ray Kinder Jr
Kenneth Walter Bair
Christopher Turchik Jagoe
Richard William Versace
Sompong Wattanasin
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE264309T1 publication Critical patent/ATE264309T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
AT99957309T 1998-11-17 1999-11-15 Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren ATE264309T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19335498A 1998-11-17 1998-11-17
PCT/EP1999/008767 WO2000029382A1 (en) 1998-11-17 1999-11-15 Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors

Publications (1)

Publication Number Publication Date
ATE264309T1 true ATE264309T1 (de) 2004-04-15

Family

ID=22713307

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99957309T ATE264309T1 (de) 1998-11-17 1999-11-15 Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren

Country Status (25)

Country Link
EP (1) EP1131297B1 (de)
JP (1) JP3550545B2 (de)
KR (1) KR20010080461A (de)
CN (1) CN1187333C (de)
AR (1) AR023914A1 (de)
AT (1) ATE264309T1 (de)
AU (1) AU748016B2 (de)
BR (1) BR9915436A (de)
CA (1) CA2347773C (de)
CO (1) CO5140099A1 (de)
CZ (1) CZ20011707A3 (de)
DE (1) DE69916488T2 (de)
ES (1) ES2221463T3 (de)
HU (1) HUP0104224A3 (de)
ID (1) ID28343A (de)
IL (1) IL142701A0 (de)
NO (1) NO20012428L (de)
PE (1) PE20001241A1 (de)
PL (1) PL347633A1 (de)
PT (1) PT1131297E (de)
SK (1) SK6692001A3 (de)
TR (1) TR200101366T2 (de)
UY (2) UY25807A1 (de)
WO (1) WO2000029382A1 (de)
ZA (1) ZA200103419B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE383341T1 (de) * 2000-05-11 2008-01-15 Novartis Pharma Gmbh Substituierte caprolactam carbonate und ether sowie deren verwendung als anti-tumor wirkstoffe
US6545148B2 (en) 2001-03-12 2003-04-08 Novartis Ag Process for preparing certain substituted caprolactams
JP2006528611A (ja) * 2003-07-25 2006-12-21 ノバルティス アクチエンゲゼルシャフト 置換ラクタムおよびそれらの抗がん剤としての使用
US7153846B2 (en) 2003-10-24 2006-12-26 Sanofi-Aventis Deutschland Gmbh Bengamide derivatives, process for preparing them, and their use
DE10349669B3 (de) * 2003-10-24 2005-05-25 Aventis Pharma Deutschland Gmbh Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2878525B1 (fr) * 2004-11-29 2007-02-23 Aventis Pharma Sa Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2878528B1 (fr) * 2004-11-29 2008-05-16 Aventis Pharma Sa 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2901556A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
FR2901554B1 (fr) 2006-05-24 2011-04-01 Sanofi Aventis 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation
FR2901555A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation
US20130085161A1 (en) 2010-06-17 2013-04-04 Novartis Ag Piperidinyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
WO2011157787A1 (en) 2010-06-17 2011-12-22 Novartis Ag Biphenyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9411841D0 (en) * 1994-06-14 1994-08-03 Pharma Mar Sa New antitumoral compounds from jaspis sponge

Also Published As

Publication number Publication date
CN1326445A (zh) 2001-12-12
DE69916488D1 (de) 2004-05-19
NO20012428D0 (no) 2001-05-16
ZA200103419B (en) 2002-06-26
AR023914A1 (es) 2002-09-04
AU1506000A (en) 2000-06-05
AU748016B2 (en) 2002-05-30
ES2221463T3 (es) 2004-12-16
TR200101366T2 (tr) 2001-10-22
PL347633A1 (en) 2002-04-22
CA2347773A1 (en) 2000-05-25
PT1131297E (pt) 2004-08-31
EP1131297B1 (de) 2004-04-14
IL142701A0 (en) 2002-03-10
HUP0104224A3 (en) 2002-04-29
KR20010080461A (ko) 2001-08-22
JP2002529536A (ja) 2002-09-10
DE69916488T2 (de) 2005-03-24
UY25807A1 (es) 2001-08-27
ID28343A (id) 2001-05-17
NO20012428L (no) 2001-07-17
WO2000029382A1 (en) 2000-05-25
UY26036A1 (es) 2001-06-29
SK6692001A3 (en) 2001-10-08
PE20001241A1 (es) 2000-11-24
CA2347773C (en) 2009-03-10
EP1131297A1 (de) 2001-09-12
CZ20011707A3 (cs) 2001-08-15
HUP0104224A2 (hu) 2002-03-28
JP3550545B2 (ja) 2004-08-04
CN1187333C (zh) 2005-02-02
CO5140099A1 (es) 2002-03-22
BR9915436A (pt) 2001-08-07

Similar Documents

Publication Publication Date Title
ATE447947T1 (de) Pharmazeutische zubereitungen zur behandlung von insulinresitenz
DE69710095D1 (de) Pharmazeutische zubereitung zur behandlung von diabetes
ATE256463T1 (de) Pharmazeutische zubereitung zur verwendung in der behandlung von diabetes
ATE204754T1 (de) Pharmazeutische zusammensetzung von metformin und fibrat, und ihre verwendung zur behandlung von hyperglykämie
ATE235481T1 (de) Substituierte benzopyranderivate zur behandlung von entzündungen
DE60019556D1 (de) 2-amino-benzoxazinonderivate zur behandlung von fettleibigkeit
ATE527022T1 (de) Verwendung von cyclooxygenase-2-inhibitoren zur behandlung und vorbeugung von tumoren, von tumor- abhängigen erkrankungen und kachexie
DE69836752D1 (de) Prostaglandinagoniste und deren verwendung zur behandlung von knochenerkrankungen
ATE318138T1 (de) Pharmazeutisches mittel zur behandlung von diabetes
DE60019555D1 (de) 2-oxy-benzoxazinonderivate zur behandlung von fettleibigkeit
ATE350030T1 (de) Nordihydroguaiaretinsäurederivate zur behandlung von tumoren
DE69804659D1 (de) 21-hydro-6,19-oxidoprogesterone (21oh-60p) und deren verwendung als arzneimittel zur behandlung von glukokortikoidüberschuss
ATE295174T1 (de) Arzneimittel zur behandlung von bluthochdruck
DE69833297D1 (de) Substituierte Pyridylmethylpiperazin- und piperidinderivate, deren Herstellung und deren Verwendung in der Behandlung von Erkrankungen des Zentralnervensystems (ZNS)
ATE264309T1 (de) Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren
EE03771B1 (et) Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine
DE69914951D1 (de) Substituierte tricyclische Verbindungen und deren Verwendung zur Behandlung von sPLA2-bedingten Erkrankungen
DE69420229T2 (de) Pharmazeutische Zusammensetzung zur Behandlung von AIDS
ATE418552T1 (de) Substituierte amino-furan-2-yl-essigsaure- und amino-thien-2-yl-essigsaure-derivate und ihre verwendung zur behandlung von migraine bzw. schmerz
DE69925578D1 (de) Pharmazeutische zusammenstellung zur vorbeugung und behandlung von mit zellkrankheiten des augenhintergrundes zusammenhängenden krankheiten
DE69738320D1 (de) Verwendung von pyrolidin-derivaten zur herstellung von arzneimitteln zur behandlung von drogenmissbrauch
DE59708511D1 (de) Verwendung von 7-(1-aminomethyl-2-oxa-7-aza-bicyclo 3.3.0]oct-7-yl)-chinoloncarbonsäure- und -naphthyridoncarbonsäure-derivaten zur therapie von helicobacter-pylori-infektionen und den damit assoziierten gastroduodenalen erkrankungen
ATE204167T1 (de) Antikonvulsive derivate zur behandlung von psoriasis
ATE288279T1 (de) Arzneimittel zur vermeidung oder behandlung von papillomavirus-spezifischem tumor
ATE261965T1 (de) Bispidin-derivate zur behandlung von herzarrhythmien

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1131297

Country of ref document: EP

REN Ceased due to non-payment of the annual fee