IL141212A0 - Process for the synthesis of (1h)-benzo [c] quinolizin-3-one derivatives - Google Patents

Process for the synthesis of (1h)-benzo [c] quinolizin-3-one derivatives

Info

Publication number
IL141212A0
IL141212A0 IL14121299A IL14121299A IL141212A0 IL 141212 A0 IL141212 A0 IL 141212A0 IL 14121299 A IL14121299 A IL 14121299A IL 14121299 A IL14121299 A IL 14121299A IL 141212 A0 IL141212 A0 IL 141212A0
Authority
IL
Israel
Prior art keywords
quinolizin
benzo
derivatives
synthesis
compounds
Prior art date
Application number
IL14121299A
Other languages
English (en)
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of IL141212A0 publication Critical patent/IL141212A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL14121299A 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo [c] quinolizin-3-one derivatives IL141212A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98114524 1998-08-03
PCT/EP1999/005277 WO2000008019A1 (en) 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo[c]quinolizin-3-ones derivatives

Publications (1)

Publication Number Publication Date
IL141212A0 true IL141212A0 (en) 2002-03-10

Family

ID=8232396

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14121299A IL141212A0 (en) 1998-08-03 1999-07-23 Process for the synthesis of (1h)-benzo [c] quinolizin-3-one derivatives
IL141212A IL141212A (en) 1998-08-03 2001-02-01 Process for making a history of (1H) - benzo - [C] - quinolizin - 3 - on

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL141212A IL141212A (en) 1998-08-03 2001-02-01 Process for making a history of (1H) - benzo - [C] - quinolizin - 3 - on

Country Status (29)

Country Link
US (1) US6723850B1 (da)
EP (1) EP1102765B1 (da)
JP (1) JP2002522435A (da)
KR (1) KR100624239B1 (da)
CN (1) CN1128148C (da)
AT (1) ATE250057T1 (da)
AU (1) AU751873B2 (da)
BG (1) BG65062B1 (da)
BR (1) BR9912870A (da)
CA (1) CA2338498C (da)
CZ (1) CZ291648B6 (da)
DE (1) DE69911430T2 (da)
DK (1) DK1102765T3 (da)
EA (1) EA003997B1 (da)
EE (1) EE04642B1 (da)
ES (1) ES2203169T3 (da)
HK (1) HK1037368A1 (da)
HU (1) HUP0103241A3 (da)
IL (2) IL141212A0 (da)
NO (1) NO20010559D0 (da)
NZ (1) NZ509243A (da)
PL (1) PL198963B1 (da)
PT (1) PT1102765E (da)
SI (1) SI1102765T1 (da)
SK (1) SK285438B6 (da)
TR (1) TR200100286T2 (da)
UA (1) UA67787C2 (da)
WO (1) WO2000008019A1 (da)
ZA (1) ZA200100365B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
DK1773816T3 (da) 2004-06-24 2015-01-26 Vertex Pharma Modulatorer af ATP-bindende kassettetransportører
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
US20090105272A1 (en) * 2005-12-24 2009-04-23 Grootenhuis Peter D J Prodrugs of modulators of ABC transporters
JP5409010B2 (ja) 2005-12-28 2014-02-05 バーテックス ファーマシューティカルズ インコーポレイテッド N−[2,4−ビス(1,1−ジメチルエチル)−5−ヒドロキシフェニル]−1,4−ジヒドロ−4−オキソキノリン−3−カルボキサミドの固体形態
NZ624460A (en) 2009-03-20 2015-12-24 Vertex Pharma Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
JP5918256B2 (ja) * 2010-12-14 2016-05-18 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト ストリゴラクタム誘導体および植物成長調節剤としてのこれらの使用
CN104470518A (zh) 2012-02-27 2015-03-25 沃泰克斯药物股份有限公司 药物组合物及其施用
CA2963945C (en) 2014-10-07 2023-01-10 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
CN105001216B (zh) * 2015-07-08 2017-03-01 中国科学院兰州化学物理研究所 一种喹嗪酮的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064961A (en) * 1989-12-18 1991-11-12 E. R. Squibb & Sons, Inc. Process for preparing an optically active cyclobutane nucleoside
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
IT1286545B1 (it) * 1996-02-09 1998-07-15 Antonio Guarna Derivati benzo(c) chinolizinici,loro preparazione ed uso come inibitori delle 5-alfa-riduttasi
JPH09316076A (ja) * 1996-05-24 1997-12-09 Nippon Paper Ind Co Ltd 9−置換プリン誘導体及びその抗ウイルス剤としての用途

Also Published As

Publication number Publication date
ZA200100365B (en) 2001-07-26
WO2000008019A1 (en) 2000-02-17
TR200100286T2 (tr) 2001-07-23
DE69911430D1 (de) 2003-10-23
EP1102765A1 (en) 2001-05-30
CZ2001434A3 (cs) 2001-08-15
UA67787C2 (uk) 2004-07-15
US6723850B1 (en) 2004-04-20
EE200100060A (et) 2002-06-17
AU6312399A (en) 2000-02-28
ATE250057T1 (de) 2003-10-15
JP2002522435A (ja) 2002-07-23
EE04642B1 (et) 2006-06-15
CZ291648B6 (cs) 2003-04-16
BR9912870A (pt) 2001-10-16
DE69911430T2 (de) 2004-07-22
PT1102765E (pt) 2003-12-31
EA200100213A1 (ru) 2001-08-27
HUP0103241A3 (en) 2002-10-28
ES2203169T3 (es) 2004-04-01
CA2338498C (en) 2009-05-19
KR100624239B1 (ko) 2006-09-13
KR20010074684A (ko) 2001-08-09
BG105198A (en) 2001-12-29
EA003997B1 (ru) 2003-12-25
IL141212A (en) 2006-12-31
CN1128148C (zh) 2003-11-19
PL198963B1 (pl) 2008-08-29
NO20010559L (no) 2001-02-01
NZ509243A (en) 2002-11-26
PL345802A1 (en) 2002-01-02
BG65062B1 (bg) 2007-01-31
SK285438B6 (sk) 2007-01-04
SI1102765T1 (en) 2003-12-31
AU751873B2 (en) 2002-08-29
DK1102765T3 (da) 2004-02-02
HUP0103241A2 (hu) 2002-01-28
CN1311788A (zh) 2001-09-05
EP1102765B1 (en) 2003-09-17
HK1037368A1 (en) 2002-02-08
SK1672001A3 (en) 2001-08-06
NO20010559D0 (no) 2001-02-01
CA2338498A1 (en) 2000-02-17

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