IL138221A0 - Formulations for protection of peg-interferon alpha conjugates - Google Patents

Formulations for protection of peg-interferon alpha conjugates

Info

Publication number
IL138221A0
IL138221A0 IL13822199A IL13822199A IL138221A0 IL 138221 A0 IL138221 A0 IL 138221A0 IL 13822199 A IL13822199 A IL 13822199A IL 13822199 A IL13822199 A IL 13822199A IL 138221 A0 IL138221 A0 IL 138221A0
Authority
IL
Israel
Prior art keywords
peg
formulations
protection
interferon alpha
alpha conjugates
Prior art date
Application number
IL13822199A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21957085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL138221(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL138221A0 publication Critical patent/IL138221A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
IL13822199A 1998-03-26 1999-03-24 Formulations for protection of peg-interferon alpha conjugates IL138221A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4890798A 1998-03-26 1998-03-26
PCT/US1999/004268 WO1999048535A1 (en) 1998-03-26 1999-03-24 Formulations for protection of peg-interferon alpha conjugates

Publications (1)

Publication Number Publication Date
IL138221A0 true IL138221A0 (en) 2001-10-31

Family

ID=21957085

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13822199A IL138221A0 (en) 1998-03-26 1999-03-24 Formulations for protection of peg-interferon alpha conjugates
IL138221A IL138221A (en) 1998-03-26 2000-09-03 Formulations for preserving PEG conjugates - interferon alpha

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL138221A IL138221A (en) 1998-03-26 2000-09-03 Formulations for preserving PEG conjugates - interferon alpha

Country Status (26)

Country Link
EP (1) EP1066059B1 (zh)
JP (3) JP3643034B2 (zh)
KR (1) KR100420642B1 (zh)
CN (1) CN1191863C (zh)
AR (1) AR014772A1 (zh)
AT (1) ATE297761T1 (zh)
AU (1) AU754002B2 (zh)
BR (1) BR9909087A (zh)
CA (1) CA2324467C (zh)
CO (1) CO5080738A1 (zh)
CZ (1) CZ302005B6 (zh)
DE (1) DE69925820T2 (zh)
ES (1) ES2241272T3 (zh)
HK (1) HK1029754A1 (zh)
HU (1) HU228877B1 (zh)
ID (1) ID28470A (zh)
IL (2) IL138221A0 (zh)
MY (1) MY119227A (zh)
NO (1) NO329916B1 (zh)
NZ (1) NZ506631A (zh)
PE (1) PE20000338A1 (zh)
PL (1) PL193286B1 (zh)
PT (1) PT1066059E (zh)
SK (1) SK285284B6 (zh)
TW (2) TWI243057B (zh)
WO (1) WO1999048535A1 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9909087A (pt) * 1998-03-26 2000-12-05 Schering Corp Formulações para proteção de conjugados peg-alfa interferon
US6362162B1 (en) 1999-04-08 2002-03-26 Schering Corporation CML Therapy
JP3712914B2 (ja) * 1999-04-08 2005-11-02 シェーリング コーポレイション 腎細胞ガン処置
US6605273B2 (en) 1999-04-08 2003-08-12 Schering Corporation Renal cell carcinoma treatment
US6923966B2 (en) 1999-04-08 2005-08-02 Schering Corporation Melanoma therapy
EP1908477A3 (en) * 2000-01-24 2008-06-11 Schering Corporation Combination of temozolomide and pegylated interferon-alpha for treating cancer
CA2397793A1 (en) * 2000-01-24 2001-07-26 Schering Corporation Combination of temozolomide and pegylated interferon-alpha for treating cancer
KR100353392B1 (ko) * 2000-03-13 2002-09-18 선바이오(주) 높은 생체 활성도를 갖는 생체 활성 단백질과 ｐｅｇ의결합체 제조방법
AU2001244713A1 (en) 2000-04-03 2001-10-15 Santen Pharmaceutical Co. Ltd. Transporters and drug delivery system by using the same
PL205936B1 (pl) 2002-02-22 2010-06-30 Schering Corp Farmaceutyczny preparat zawierający termozolomid oraz sposób jego wytwarzania
AU2008201682B2 (en) * 2004-02-02 2011-02-24 Ambrx, Inc. Modified human interferon polypeptides and their uses
CN101039660B (zh) * 2004-08-12 2010-10-06 先灵公司 稳定的聚乙二醇化干扰素制剂
RS52417B (en) 2007-12-20 2013-02-28 Merck Serono S.A. PEG-INTERFERON-BETA FORMULATIONS
KR101303388B1 (ko) * 2010-10-26 2013-09-03 한미사이언스 주식회사 지속형 인터페론 알파 결합체의 액상 제제
KR20150074167A (ko) * 2012-10-26 2015-07-01 루핀 리미티드 Ｐｅｇ 인터페론 알파-2ｂ의 안정한 약학 조성물
KR101736870B1 (ko) * 2014-08-20 2017-05-18 한국코러스 주식회사 인터페론 접합체를 포함하는 복합체 및 이의 제조방법
SI3463308T1 (sl) 2016-06-01 2022-04-29 Servier IP UK Limited Formulacije polialkilenoksidne asparaginaze in postopki za pripravo in uporabo le-teh
CN112358541B (zh) * 2020-11-25 2022-04-01 广州迪澳医疗科技有限公司 一种重组人γ-干扰素的冻干保护剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2024046A1 (en) * 1989-09-28 1991-03-29 Alberto Ferro Stabilized leukocyte-interferons
US5382657A (en) * 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
ES2174915T3 (es) * 1993-11-10 2002-11-16 Enzon Inc Productos de conjugacion mejorados de un interferon con un polimero.
US5766582A (en) * 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
US5738846A (en) * 1994-11-10 1998-04-14 Enzon, Inc. Interferon polymer conjugates and process for preparing the same
AU695129B2 (en) * 1995-02-06 1998-08-06 Genetics Institute, Llc Formulations for IL-12
JP2758154B2 (ja) * 1995-04-06 1998-05-28 エフ・ホフマン−ラ ロシユ アーゲー インターフェロンを含む液体製剤
CN1151842C (zh) * 1995-07-27 2004-06-02 基因技术股份有限公司 稳定等渗的冻干蛋白制剂
EP0858343B1 (en) * 1995-11-02 2004-03-31 Schering Corporation Continuous low-dose cytokine infusion therapy
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
TW517067B (en) * 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
BR9909087A (pt) * 1998-03-26 2000-12-05 Schering Corp Formulações para proteção de conjugados peg-alfa interferon

Also Published As

Publication number Publication date
JP2002507583A (ja) 2002-03-12
JP2003221345A (ja) 2003-08-05
JP4580744B2 (ja) 2010-11-17
IL138221A (en) 2007-12-03
ATE297761T1 (de) 2005-07-15
ES2241272T3 (es) 2005-10-16
HUP0101749A2 (hu) 2001-11-28
BR9909087A (pt) 2000-12-05
MY119227A (en) 2005-04-30
NO20004785D0 (no) 2000-09-25
CZ302005B6 (cs) 2010-09-01
TWI243057B (en) 2005-11-11
AU3181299A (en) 1999-10-18
HUP0101749A3 (en) 2001-12-28
EP1066059B1 (en) 2005-06-15
NZ506631A (en) 2003-03-28
NO329916B1 (no) 2011-01-24
TWI250024B (en) 2006-03-01
PL193286B1 (pl) 2007-01-31
CA2324467A1 (en) 1999-09-30
NO20004785L (no) 2000-09-25
PE20000338A1 (es) 2000-05-16
ID28470A (id) 2001-05-24
TW200536557A (en) 2005-11-16
HK1029754A1 (en) 2001-04-12
PL345568A1 (en) 2001-12-17
SK14262000A3 (sk) 2001-04-09
PT1066059E (pt) 2005-10-31
CN1191863C (zh) 2005-03-09
KR20010034654A (ko) 2001-04-25
CA2324467C (en) 2002-11-05
DE69925820T2 (de) 2006-05-18
HU228877B1 (en) 2013-06-28
DE69925820D1 (de) 2005-07-21
JP2005104985A (ja) 2005-04-21
JP3643034B2 (ja) 2005-04-27
KR100420642B1 (ko) 2004-03-02
CZ20003315A3 (cs) 2001-04-11
CN1295484A (zh) 2001-05-16
WO1999048535A1 (en) 1999-09-30
SK285284B6 (sk) 2006-10-05
CO5080738A1 (es) 2001-09-25
AR014772A1 (es) 2001-03-28
AU754002B2 (en) 2002-10-31
EP1066059A1 (en) 2001-01-10

Similar Documents

Publication Publication Date Title
SG79255A1 (en) Pharmaceutical formulations
IL223035A0 (en) Extended release formulations of clarithromycin
IS2325B (is) Örgerðar samsetningar epleróns
PL343021A1 (en) Formulations
IL138221A0 (en) Formulations for protection of peg-interferon alpha conjugates
PL343429A1 (en) Combined vaccine compositions
IL137999A0 (en) Vaccine compositions
HUP0103507A3 (en) Pharmaceutical compositions comprising 2-quinolones
PL343627A1 (en) Medicinal compositions
HK1046109A1 (zh) Usmanov的保護殼體
TW388280U (en) Improved structure of protection pad for goggles
GB9809213D0 (en) Pharmaceutical compositions
GB9806312D0 (en) Novel formulations
GB9802472D0 (en) Pharmaceutical compositions
GB9815001D0 (en) Formulations
GB9815002D0 (en) Formulations
GB9806487D0 (en) Pharmaceutical compositions
GB9810181D0 (en) Novel formulations
TW468496U (en) Improved structure of protective kneecap
TW364362U (en) Improvement on structure of protection mouth-muffle
GB2341552B (en) Protective compositions
PL326575A1 (en) Agent for all-aspect protection of wood
GB9828205D0 (en) Pharmaceutical formulations
GB9807556D0 (en) Pharmaceutical formulations
GB9813452D0 (en) Pharmaceutical formulations

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed