IL138078A - Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants - Google Patents

Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants

Info

Publication number
IL138078A
IL138078A IL13807899A IL13807899A IL138078A IL 138078 A IL138078 A IL 138078A IL 13807899 A IL13807899 A IL 13807899A IL 13807899 A IL13807899 A IL 13807899A IL 138078 A IL138078 A IL 138078A
Authority
IL
Israel
Prior art keywords
disintegrants
tablets
super
formulation
fast
Prior art date
Application number
IL13807899A
Other languages
English (en)
Other versions
IL138078A0 (en
Original Assignee
Bristom Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22160544&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL138078(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristom Myers Squibb Pharma Co filed Critical Bristom Myers Squibb Pharma Co
Publication of IL138078A0 publication Critical patent/IL138078A0/xx
Publication of IL138078A publication Critical patent/IL138078A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL13807899A 1998-04-07 1999-04-01 Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants IL138078A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8092598P 1998-04-07 1998-04-07
PCT/US1999/007228 WO1999051239A1 (en) 1998-04-07 1999-04-01 Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants

Publications (2)

Publication Number Publication Date
IL138078A0 IL138078A0 (en) 2001-10-31
IL138078A true IL138078A (en) 2005-12-18

Family

ID=22160544

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13807899A IL138078A (en) 1998-04-07 1999-04-01 Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants

Country Status (27)

Country Link
US (2) US6238695B1 (cs)
EP (1) EP1067936B1 (cs)
JP (1) JP2002510634A (cs)
KR (1) KR100634253B1 (cs)
CN (1) CN1146419C (cs)
AR (1) AR019031A1 (cs)
AT (1) ATE223719T1 (cs)
AU (1) AU756422B2 (cs)
BR (1) BR9908810A (cs)
CA (1) CA2321523C (cs)
CZ (1) CZ300850B6 (cs)
DE (1) DE69902893T2 (cs)
DK (1) DK1067936T3 (cs)
EA (1) EA003217B1 (cs)
EE (1) EE04391B1 (cs)
ES (1) ES2181417T3 (cs)
HU (1) HU228498B1 (cs)
IL (1) IL138078A (cs)
NO (1) NO325824B1 (cs)
NZ (1) NZ507566A (cs)
PL (1) PL194309B1 (cs)
PT (1) PT1067936E (cs)
SK (1) SK284655B6 (cs)
TW (1) TW576741B (cs)
UA (1) UA72207C2 (cs)
WO (1) WO1999051239A1 (cs)
ZA (1) ZA200004313B (cs)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72207C2 (uk) * 1998-04-07 2005-02-15 Брістол- Майєрс Сквібб Фарма Компані Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
US20010014352A1 (en) 1998-05-27 2001-08-16 Udit Batra Compressed tablet formulation
EP1332757B1 (en) * 1998-05-27 2012-06-13 Merck Sharp & Dohme Corp. Efavirenz compressed tablet formulation
DK1083885T3 (da) * 1998-06-11 2007-02-26 Pharmacia & Upjohn Co Llc Delavirdintabletformulering
US7037524B2 (en) * 2001-10-03 2006-05-02 Herbalscience, Llc Oral delivery of a botanical
US20050069596A1 (en) * 2001-10-03 2005-03-31 Gow Robert T. Compositions and methods comprising kava and anti-anxiety compounds
US20050053678A1 (en) * 2001-10-03 2005-03-10 Gow Robert T. Methods and compositions for betel nut chewing gum
US7291352B2 (en) 2001-10-03 2007-11-06 Herbalscience Llc Methods and compositions for oral delivery of Areca and mate' or theobromine
AU2002359518A1 (en) * 2001-11-27 2003-06-10 Bristol-Myers Squibb Company Efavirenz tablet formulation having unique biopharmaceutical characteristics
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20050037025A1 (en) * 2002-10-03 2005-02-17 Gow Robert T. Methods and compositions comprising kava and mate' or theobromine
EA015145B1 (ru) 2003-01-14 2011-06-30 Джилид Сайэнс, Инк. Фармацевтическая композиция и пероральная фармацевтическая дозированная форма (варианты), проявляющие активность в отношении вич-инфекций, лечебный набор и таблетка и способ лечения или предотвращения симптомов или эффектов вич-инфекции
WO2006020962A2 (en) 2004-08-13 2006-02-23 Gallipot, Inc. Palatable suspending vehicle for pharmaceutical ingredients
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
CN101272848B (zh) * 2005-07-28 2013-03-13 Isp投资有限公司 改进喷雾干燥的粉末和颗粒材料性质的方法，以及由此生产的产品
WO2007013047A2 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited Water-dispersible anti-retroviral pharmaceutical compositions
US20080317852A1 (en) * 2005-12-14 2008-12-25 Amar Lulla Pharmaceutical Combination
WO2008008120A1 (en) * 2006-07-14 2008-01-17 Fmc Corporation Solid form
WO2008033487A2 (en) * 2006-09-14 2008-03-20 Chemlink Laboratories Llc Method for preparing solid dosage forms that form a paste, cream or gel when diluted for final use
US20080152717A1 (en) * 2006-12-14 2008-06-26 Isp Investments, Inc. Amorphous valsartan and the production thereof
US8613946B2 (en) * 2006-12-21 2013-12-24 Isp Investment Inc. Carotenoids of enhanced bioavailability
US20080181961A1 (en) * 2007-01-26 2008-07-31 Isp Investments, Inc. Amorphous oxcarbazepine and the production thereof
US10189957B2 (en) * 2007-01-26 2019-01-29 Isp Investments Llc Formulation process method to produce spray dried products
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
JP2010536798A (ja) * 2007-08-17 2010-12-02 テバ ファーマシューティカル インダストリーズ リミティド 難溶性薬物の生体利用率を制御するための方法及び組成物
WO2010008719A2 (en) * 2008-06-16 2010-01-21 Schering Corporation Oral pharmaceutical formulations of vla-4 antagonists
WO2010125572A1 (en) * 2009-04-29 2010-11-04 Hetero Research Foundation Compressed tablets and capsules containing efavirenz
UA105556C2 (uk) 2010-01-27 2014-05-26 Віів Гелскер Компані Комбінація сполук, що містить інгібітори віл інтегрази з іншими терапевтичними агентами
BR112012026843A2 (pt) * 2010-04-20 2016-07-12 Cipla Ltd composição, composição farmacêutica, processo para preparar uma composição farmacêutica, uso de uma composição e método para tratamento de hiv
CN104203275A (zh) 2010-06-09 2014-12-10 疫苗技术股份有限公司 用于增强抗逆转录病毒治疗的hiv感染者的治疗性免疫
CN102872019A (zh) * 2012-09-17 2013-01-16 北京阜康仁生物制药科技有限公司 一种采用微粉化技术的依非韦伦制剂
WO2015059466A1 (en) 2013-10-25 2015-04-30 Cipla Limited Pharmaceutical compositions comprising efavirenz
PE20180690A1 (es) 2015-04-27 2018-04-23 Intercept Pharmaceuticals Inc Composiciones de acido obeticolico y metodos de uso
WO2017029225A1 (en) 2015-08-14 2017-02-23 Sandoz Ag Solid pharmaceutical composition of abacavir, lamivudine, and efavirenz
CN114404377B (zh) * 2022-01-10 2023-07-25 安徽贝克生物制药有限公司 一种阿巴卡韦、拉米夫定、依非韦伦复方片及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7084587A (en) 1986-04-01 1987-10-20 Upjohn Company, The Methylprednisolone/sodium carboxymethyl starch tablet composition
HU205717B (en) * 1989-04-28 1992-06-29 Daiichi Seiyaku Co Process for producing pharmaceutical composition against human immunodeficiency, comprising pyridionecarboxylic acid derivative
ES2106852T3 (es) * 1992-07-08 1997-11-16 Santen Oy Composicion oftalmica que contiene hemihidrato de timolol.
US5663169A (en) 1992-08-07 1997-09-02 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
WO1995020389A1 (en) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
US5663467A (en) * 1995-01-23 1997-09-02 Merck & Co., Inc. Synthesis of cyclopropylacetylene
IT1281502B1 (it) * 1995-06-13 1998-02-18 Sardinian Antiviral Research C Impiego di un inibitore non nucleosidico della trascrittasi inversa in associazione con inibitori nucleosidici per il trattamento della
UA72207C2 (uk) * 1998-04-07 2005-02-15 Брістол- Майєрс Сквібб Фарма Компані Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
PE20000559A1 (es) 1998-05-27 2000-07-05 Merck & Co Inc Formulacion de tabletas comprimidas de efavirenz

Also Published As

Publication number Publication date
EE200000589A (et) 2002-04-15
ATE223719T1 (de) 2002-09-15
US6238695B1 (en) 2001-05-29
EP1067936B1 (en) 2002-09-11
US6555133B2 (en) 2003-04-29
HUP0101517A2 (hu) 2001-11-28
AR019031A1 (es) 2001-12-26
HUP0101517A3 (en) 2002-11-28
PL194309B1 (pl) 2007-05-31
CZ20003571A3 (cs) 2001-01-17
ZA200004313B (en) 2002-01-30
KR100634253B1 (ko) 2006-10-16
EA003217B1 (ru) 2003-02-27
AU3463799A (en) 1999-10-25
EP1067936A1 (en) 2001-01-17
DK1067936T3 (da) 2003-02-17
DE69902893D1 (de) 2002-10-17
CN1296412A (zh) 2001-05-23
UA72207C2 (uk) 2005-02-15
DE69902893T2 (de) 2003-04-30
NZ507566A (en) 2002-11-26
CN1146419C (zh) 2004-04-21
SK14612000A3 (sk) 2001-07-10
US20010012518A1 (en) 2001-08-09
CA2321523A1 (en) 1999-10-14
NO20005043L (no) 2000-10-06
ES2181417T3 (es) 2003-02-16
KR20010042473A (ko) 2001-05-25
JP2002510634A (ja) 2002-04-09
NO325824B1 (no) 2008-07-21
CZ300850B6 (cs) 2009-08-26
WO1999051239A1 (en) 1999-10-14
CA2321523C (en) 2008-10-07
EE04391B1 (et) 2004-12-15
IL138078A0 (en) 2001-10-31
PL343421A1 (en) 2001-08-13
TW576741B (en) 2004-02-21
SK284655B6 (sk) 2005-08-04
HU228498B1 (en) 2013-03-28
BR9908810A (pt) 2000-12-19
NO20005043D0 (no) 2000-10-06
PT1067936E (pt) 2002-12-31
EA200001030A1 (ru) 2001-04-23
AU756422B2 (en) 2003-01-09

Similar Documents

Publication Publication Date Title
IL138078A0 (en) Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants
PL343491A1 (en) Pharmaceutical aerosol formulation
HUP0004534A3 (en) Pharmaceutical formulation containing olanzapine
PT1052974E (pt) Formulação farmacêutica contendo epotilona
IL146632A0 (en) Pharmaceutical tablets
PL360885A1 (en) 10-aryl-11h-benzo [b]fluorene derivatives and analogs for medicinal use
IL134521A (en) Pharmaceutical composition for enhancing the bioavailability of fexofenadine and its derivatives
PL337799A1 (en) Sertralin dosage forms of retarded release
GB9818927D0 (en) Pharmaceutical formulation
NO20002114D0 (no) Bicykliske forbindelser, fremgangsmÕte for deres fremstilling og farmasøytiske sammensetninger inneholdende dem
SI1067936T1 (en) Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants
GB9909154D0 (en) Pharmaceutical formulation
GB9817470D0 (en) Pharmaceutical formulation
GB9822333D0 (en) Pharmaceutical formulation
GB9926251D0 (en) Pharmaceutical formulation
GB9802617D0 (en) Pharmaceutical formulation
GB9811622D0 (en) Drug formulation
GB9824502D0 (en) Pharmaceutical formulation
GB9826767D0 (en) Pharmaceutical formulation
GB9817217D0 (en) Pharmaceutical formulation
GB9808152D0 (en) Pharmaceutical aerosol formulation
GB9814709D0 (en) Pharmaceutical aerosol formulation
SI1073417T1 (en) Pharmaceutical aerosol formulation
GB9917774D0 (en) Pharmaceutical formulation
GB9921396D0 (en) Pharmaceutical formulation

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired