IL136051A0 - Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol - Google Patents
Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprolInfo
- Publication number
- IL136051A0 IL136051A0 IL13605198A IL13605198A IL136051A0 IL 136051 A0 IL136051 A0 IL 136051A0 IL 13605198 A IL13605198 A IL 13605198A IL 13605198 A IL13605198 A IL 13605198A IL 136051 A0 IL136051 A0 IL 136051A0
- Authority
- IL
- Israel
- Prior art keywords
- arsenic trioxide
- melarsoprol
- methods
- treating cancer
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/285—Arsenic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/36—Arsenic; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6465597P | 1997-11-10 | 1997-11-10 | |
PCT/US1998/024024 WO1999024029A1 (en) | 1997-11-10 | 1998-11-10 | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
Publications (1)
Publication Number | Publication Date |
---|---|
IL136051A0 true IL136051A0 (en) | 2001-05-20 |
Family
ID=22057410
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13605198A IL136051A0 (en) | 1997-11-10 | 1998-11-10 | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
Country Status (20)
Country | Link |
---|---|
US (22) | US6770304B2 (el) |
EP (3) | EP1964557B1 (el) |
JP (2) | JP2001522799A (el) |
KR (1) | KR20010031938A (el) |
CN (1) | CN1285743A (el) |
AU (1) | AU747474C (el) |
BR (1) | BR9814857A (el) |
CA (1) | CA2309652C (el) |
CY (1) | CY1113856T1 (el) |
DK (1) | DK2255800T3 (el) |
ES (2) | ES2395515T3 (el) |
HK (1) | HK1150762A1 (el) |
ID (1) | ID25622A (el) |
IL (1) | IL136051A0 (el) |
NO (1) | NO20002409L (el) |
NZ (1) | NZ504585A (el) |
PL (1) | PL343868A1 (el) |
PT (2) | PT1964557E (el) |
TR (1) | TR200002243T2 (el) |
WO (1) | WO1999024029A1 (el) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1044559C (zh) * | 1995-08-23 | 1999-08-11 | 哈尔滨医科大学附属第一医院 | 抗白血病、肝癌、淋巴瘤注射液 |
EP1419778A1 (en) | 1997-10-15 | 2004-05-19 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
DK2255800T3 (da) * | 1997-11-10 | 2013-02-04 | Sloan Kettering Inst Cancer | Arsentrioxid til anvendelse ved behandling af leukæmi |
CN1233476A (zh) * | 1998-04-24 | 1999-11-03 | 陆道培 | 治疗急性白血病的药物及其制备方法 |
KR100272835B1 (ko) * | 1998-05-08 | 2000-11-15 | 배일주 | 천연 화학물질 육산화사비소의 신규한 항종양 치료제로서의 용도 및 그 약학적 조성물 |
KR100399657B1 (ko) | 2000-06-29 | 2003-09-29 | 배일주 | 혈관신생 억제제 |
DE60140063D1 (de) * | 2000-08-08 | 2009-11-12 | Immunomedics Inc | Immuntherapie für kronische myelozytische leukämie mit nacktem anti-nca-90 antikörper |
CN1332672C (zh) * | 2001-03-15 | 2007-08-22 | 张鹏 | 一种三氧化二砷注射粉剂 |
KR20020083678A (ko) * | 2001-04-28 | 2002-11-04 | 주식회사 한국미생물연구소 | 아르세닉산나트륨 염, 소디움 메타아르세나이트 또는 이의혼합물을 함유한 항암제 조성물 |
US20040110691A1 (en) * | 2001-11-13 | 2004-06-10 | Stamler Jonathan S. | Thiol reactive agents as a therapeutic modality |
KR20030058019A (ko) * | 2001-12-29 | 2003-07-07 | 한국원자력연구소 | 삼산화비소(As₂O₃)를 유효 성분으로 포함하는 방사선치료증진제 |
EP2462932A1 (en) | 2002-01-07 | 2012-06-13 | Board Of Regents, The University Of Texas System | S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer |
KR20030075017A (ko) * | 2002-03-15 | 2003-09-22 | 한국원자력연구소 | 삼산화비소를 포함하는 혈관신생억제제 |
FR2838965B1 (fr) | 2002-04-26 | 2004-06-25 | Centre Nat Rech Scient | Therapie par l'arsenic du syndrome autoimmunlymphoproliferatif de type apls chez la souris comme chez l'homme |
EP1356820A1 (en) * | 2002-04-26 | 2003-10-29 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | DNA vaccine combined with an inducer of tumor cell apoptosis |
US8394422B2 (en) | 2002-04-26 | 2013-03-12 | Centre National De La Recherche Scientifique (Cnrs) | Arsenic therapy for autoimmune and/or inflammatory diseases in mice and humans |
US20080166425A1 (en) * | 2002-10-09 | 2008-07-10 | The University Of Hong Kong | Method for inhibiting cancer using arsenic trioxide |
US7521071B2 (en) * | 2002-10-09 | 2009-04-21 | Versitech Limited | Formulation of oral compositions comprising arsenic trioxide and methods of use thereof |
US20080089949A1 (en) * | 2006-10-13 | 2008-04-17 | Yok-Lam Kwong | Method for treating cancer using oral arsenic trioxide |
US8906422B2 (en) * | 2002-10-09 | 2014-12-09 | The University Of Hong Kong | Method for inhibiting cancer using arsenic trioxide |
TWI296527B (en) * | 2003-04-23 | 2008-05-11 | Inst Of Nuclear Energy Res Rocaec | Radioactive aesenic-containing compounds and their uses in the treatment of tumors |
GB0317020D0 (en) * | 2003-07-21 | 2003-08-27 | Sahajanand Biotech Private Ltd | Herbo-mineral formulation for refractory leukemias and lymphomas |
CN1304053C (zh) * | 2003-08-13 | 2007-03-14 | 上海第二医科大学附属瑞金医院 | 一种可治愈急性早幼粒细胞白血病的组合药物 |
FR2860719B1 (fr) * | 2003-10-10 | 2006-04-28 | Assist Publ Hopitaux De Paris | Utilisation de derives organoarsenies ou organostibiques pour leurs proprietes anticancereuses |
KR100632250B1 (ko) | 2004-02-16 | 2006-10-11 | 정태호 | 비소 화합물을 유효성분으로 하는 항암제 |
US20050196464A1 (en) * | 2004-03-03 | 2005-09-08 | Tty Biopharm Company Limited | Method and pharmaceutical composition for treatment of skin neoplasm |
TW201440760A (zh) * | 2004-07-16 | 2014-11-01 | Texas A & M Univ Sys | 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物 |
EP1721615A1 (en) | 2005-05-09 | 2006-11-15 | Komipharm International Co., Ltd. | Pharmaceutical compositions comprising sodium or potassium arsenite for the treatment of urogenital cancer and its metastasis |
US20060292243A1 (en) * | 2005-06-24 | 2006-12-28 | Shao-Chi Hsin | Arsenic compounds for the treatment of the arsenic-sensitive blast-cell related diseases |
ES2531159T3 (es) | 2005-07-29 | 2015-03-11 | Solasia Pharma K K | Compuestos y métodos para el tratamiento del cáncer |
WO2007035755A2 (en) * | 2005-09-19 | 2007-03-29 | Duke University | Methods of treating hematological malignancies |
US20080233207A1 (en) * | 2006-01-04 | 2008-09-25 | Sheptovitsky Yelena G | Injectable and Infusable Mercury Compositions and Methods for Treating Cancer |
CN104109177A (zh) | 2006-01-13 | 2014-10-22 | 得克萨斯州A&M大学系统 | 用于治疗癌症的化合物和方法 |
TW200829261A (en) | 2006-09-29 | 2008-07-16 | Ziopharm Oncology Inc | Method for controlling angiogenesis in animals |
US20080089951A1 (en) * | 2006-10-11 | 2008-04-17 | The University Of Hong Kong | Method for Inhibiting Cancer Using Arsenic Trioxide |
KR101009893B1 (ko) * | 2007-04-06 | 2011-01-20 | 주식회사 엘지화학 | 고순도 헤테로폴리산의 신규한 제조방법 |
AU2008325243B2 (en) | 2007-11-02 | 2014-07-03 | Solasia Pharma K.K. | Combination therapy with organic arsenicals |
AU2008335705A1 (en) * | 2007-12-12 | 2009-06-18 | Solasia Pharma K.K. | Compounds and methods for the treatment of cancer |
US8650648B2 (en) | 2008-03-26 | 2014-02-11 | Sophos Limited | Method and system for detecting restricted content associated with retrieved content |
US20090246291A1 (en) * | 2008-03-27 | 2009-10-01 | Angelika Burger | Method and compositions for treatment of cancer |
KR20180103194A (ko) | 2008-08-20 | 2018-09-18 | 솔레이지아 파마 가부시키가이샤 | 암 치료를 위한 유기 비소 화합물 및 방법 |
EP2475362B1 (en) * | 2009-09-10 | 2019-03-27 | Kominox, Inc. | Cancer stem cell-targeted and drug resistant cancer therapy |
US8795738B2 (en) | 2009-11-12 | 2014-08-05 | Board Of Regents Of The University Of Texas System | Use of arsenic for cancer therapy protection |
US8834938B2 (en) | 2011-05-18 | 2014-09-16 | Board Of Regents Of The University Of Texas System | Use of arsenic for cancer therapy protection |
JP5512057B2 (ja) | 2012-03-30 | 2014-06-04 | パナソニック株式会社 | 円筒型電池 |
KR20150056848A (ko) | 2012-09-20 | 2015-05-27 | 요게시 나라얀 벤데일 | 나노 삼산화비소의 생합성 방법 및 이의 암을 포함한 질환의 치료 용도 |
BR112015006656A8 (pt) * | 2012-10-08 | 2020-01-21 | Sensun Shanghai Science & Tech Co Ltd | composições e métodos para o tratamento de insuficiência cardíaca em pacientes diabéticos |
US11077139B2 (en) | 2013-12-30 | 2021-08-03 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Combination of an arsenic compound and at least one retinoid for treating acute myeloid leukemia |
CA2974843C (en) | 2015-01-29 | 2023-08-08 | Eupharma Pty Ltd | Compositions containing arsenic and their use in methods of treatment |
TWI790191B (zh) * | 2015-02-01 | 2023-01-21 | 美商錫羅斯製藥公司 | 用於病患口服之含砷高表面積冷凍乾燥組合物 |
KR102015858B1 (ko) * | 2015-10-23 | 2019-08-30 | 손영태 | 법제된 비상을 함유하는 면역력 증강을 위한 약학적 조성물 |
KR102548836B1 (ko) | 2016-02-25 | 2023-07-03 | 삼성디스플레이 주식회사 | 표시 장치 |
US9700580B1 (en) * | 2016-06-14 | 2017-07-11 | Marguerite Harning | Method for cancer treatment |
DK3548044T3 (en) | 2016-12-01 | 2023-12-11 | Eupharma Pty Ltd | Arsenic compositions |
KR101844050B1 (ko) | 2016-12-09 | 2018-05-14 | 주식회사 케마스 | 육산화사비소의 결정다형을 포함하는 암 예방 또는 치료용 약학 조성물 |
CN113491710A (zh) * | 2017-02-24 | 2021-10-12 | 四川兴科蓉药业有限责任公司 | β-As4S4在制备用于治疗血液系统恶性肿瘤的药物中的用途 |
WO2019109095A1 (en) * | 2017-12-01 | 2019-06-06 | Beth Israel Deaconess Medical Center, Inc. | Arsenic trioxide and retinoic acid compounds for treatment of idh2-associated disorders |
GB201800736D0 (en) * | 2018-01-17 | 2018-02-28 | St Georges Hospital Medical School | Combination therapy for treatment of leukemia |
WO2020117868A1 (en) * | 2018-12-03 | 2020-06-11 | Beth Israel-Deaconess Medical Center, Inc. | Arsenic compounds and retinoic acid compounds for treatment of idh-associated disorders |
WO2020117867A1 (en) * | 2018-12-03 | 2020-06-11 | Beth Israel-Deaconess Medical Center, Inc. | Darinaparsin and retinoic acid compounds for treatment of idh-associated disorders |
CN110101713A (zh) * | 2019-05-16 | 2019-08-09 | 上海交通大学医学院附属第九人民医院 | 一种三氧化二砷组合物的应用 |
EP3972613B1 (en) * | 2019-05-21 | 2023-05-03 | Medsenic | Use of copper ions to potentiate the therapeutic effects of arsenic |
CN112675197A (zh) * | 2021-01-22 | 2021-04-20 | 中山大学孙逸仙纪念医院 | 一种用于儿童Hedgehog信号通路驱动肿瘤的药物组合物 |
US11583552B2 (en) | 2021-02-17 | 2023-02-21 | Manoj Maniar | Pharmaceutical formulation of arsenic trioxide |
CN117137932B (zh) * | 2023-10-18 | 2024-04-19 | 中国中医科学院中药研究所 | 一种用于肿瘤的中药复方制剂及其应用 |
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EP1419778A1 (en) | 1997-10-15 | 2004-05-19 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
AU2002300339B2 (en) | 1997-11-10 | 2006-03-02 | Sloan-Kettering Institute For Cancer Research | Process For Producing Arsenic Trioxide Formulations And Methods For Treating Cancer Using Arsenic Trioxide Or Melarsoprol |
AU2006202364B2 (en) | 1997-11-10 | 2009-05-28 | Sloan-Kettering Institute For Cancer Research | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
DK2255800T3 (da) | 1997-11-10 | 2013-02-04 | Sloan Kettering Inst Cancer | Arsentrioxid til anvendelse ved behandling af leukæmi |
CN1233476A (zh) | 1998-04-24 | 1999-11-03 | 陆道培 | 治疗急性白血病的药物及其制备方法 |
-
1998
- 1998-11-10 DK DK10177319.0T patent/DK2255800T3/da active
- 1998-11-10 BR BR9814857-5A patent/BR9814857A/pt not_active Application Discontinuation
- 1998-11-10 JP JP2000520121A patent/JP2001522799A/ja not_active Withdrawn
- 1998-11-10 US US09/189,965 patent/US6770304B2/en not_active Expired - Lifetime
- 1998-11-10 PT PT80752009T patent/PT1964557E/pt unknown
- 1998-11-10 EP EP08075200A patent/EP1964557B1/en not_active Expired - Lifetime
- 1998-11-10 TR TR2000/02243T patent/TR200002243T2/xx unknown
- 1998-11-10 PL PL98343868A patent/PL343868A1/xx unknown
- 1998-11-10 IL IL13605198A patent/IL136051A0/xx unknown
- 1998-11-10 CA CA2309652A patent/CA2309652C/en not_active Expired - Lifetime
- 1998-11-10 CN CN98813016A patent/CN1285743A/zh active Pending
- 1998-11-10 ES ES10177319T patent/ES2395515T3/es not_active Expired - Lifetime
- 1998-11-10 EP EP10177319A patent/EP2255800B1/en not_active Expired - Lifetime
- 1998-11-10 EP EP98957803A patent/EP1037625A4/en not_active Ceased
- 1998-11-10 ID IDW20001111A patent/ID25622A/id unknown
- 1998-11-10 WO PCT/US1998/024024 patent/WO1999024029A1/en not_active Application Discontinuation
- 1998-11-10 KR KR1020007005045A patent/KR20010031938A/ko not_active Application Discontinuation
- 1998-11-10 AU AU13973/99A patent/AU747474C/en not_active Expired
- 1998-11-10 PT PT101773190T patent/PT2255800E/pt unknown
- 1998-11-10 NZ NZ504585A patent/NZ504585A/en unknown
- 1998-11-10 ES ES08075200T patent/ES2399480T3/es not_active Expired - Lifetime
-
2000
- 2000-05-09 NO NO20002409A patent/NO20002409L/no not_active Application Discontinuation
-
2002
- 2002-09-30 US US10/259,950 patent/US20030099719A1/en not_active Abandoned
-
2003
- 2003-04-30 US US10/425,785 patent/US6723351B2/en not_active Expired - Lifetime
-
2004
- 2004-01-16 US US10/758,994 patent/US6861076B2/en not_active Expired - Lifetime
- 2004-01-16 US US10/759,308 patent/US20040146576A1/en not_active Abandoned
- 2004-01-16 US US10/759,882 patent/US20040146583A1/en not_active Abandoned
- 2004-01-16 US US10/758,800 patent/US20040146568A1/en not_active Abandoned
- 2004-01-16 US US10/758,996 patent/US20040146572A1/en not_active Abandoned
- 2004-01-16 US US10/759,290 patent/US6982096B2/en not_active Expired - Lifetime
- 2004-01-16 US US10/759,716 patent/US20040146581A1/en not_active Abandoned
- 2004-01-16 US US10/759,726 patent/US20040146582A1/en not_active Abandoned
- 2004-01-16 US US10/759,291 patent/US6884439B2/en not_active Expired - Lifetime
- 2004-01-16 US US10/759,314 patent/US20040146578A1/en not_active Abandoned
- 2004-01-16 US US10/758,995 patent/US20040146571A1/en not_active Abandoned
- 2004-01-16 US US10/759,293 patent/US20040146575A1/en not_active Abandoned
- 2004-01-16 US US10/758,993 patent/US20040146569A1/en not_active Abandoned
- 2004-01-16 US US10/759,313 patent/US20040146577A1/en not_active Abandoned
- 2004-01-16 US US10/759,616 patent/US6855339B2/en not_active Expired - Lifetime
- 2004-01-16 US US10/759,439 patent/US20040146579A1/en not_active Abandoned
- 2004-01-16 US US10/759,657 patent/US20040146580A1/en not_active Abandoned
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2005
- 2005-09-30 US US11/239,704 patent/US7879364B2/en not_active Expired - Fee Related
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2010
- 2010-04-21 JP JP2010097879A patent/JP2010184926A/ja active Pending
- 2010-12-21 US US12/974,076 patent/US8273379B2/en not_active Expired - Fee Related
-
2011
- 2011-05-16 HK HK11104793.8A patent/HK1150762A1/xx not_active IP Right Cessation
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2013
- 2013-03-29 CY CY20131100265T patent/CY1113856T1/el unknown
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