IL131713A - Dosage forms comprising separate portions of r- and s-enantiomers - Google Patents

Dosage forms comprising separate portions of r- and s-enantiomers

Info

Publication number
IL131713A
IL131713A IL13171398A IL13171398A IL131713A IL 131713 A IL131713 A IL 131713A IL 13171398 A IL13171398 A IL 13171398A IL 13171398 A IL13171398 A IL 13171398A IL 131713 A IL131713 A IL 131713A
Authority
IL
Israel
Prior art keywords
enantiomer
dosage form
form according
enantiomers
different
Prior art date
Application number
IL13171398A
Other languages
English (en)
Other versions
IL131713A0 (en
Original Assignee
Arakis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9704978.7A external-priority patent/GB9704978D0/en
Priority claimed from GBGB9719261.1A external-priority patent/GB9719261D0/en
Application filed by Arakis Ltd filed Critical Arakis Ltd
Publication of IL131713A0 publication Critical patent/IL131713A0/xx
Publication of IL131713A publication Critical patent/IL131713A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
IL13171398A 1997-03-11 1998-03-11 Dosage forms comprising separate portions of r- and s-enantiomers IL131713A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9704978.7A GB9704978D0 (en) 1997-03-11 1997-03-11 Dosage forms
GBGB9719261.1A GB9719261D0 (en) 1997-09-10 1997-09-10 Dosage forms
PCT/GB1998/000726 WO1998040053A1 (en) 1997-03-11 1998-03-11 Dosage forms comprising separate portions of r- and s-enantiomers
US09/038,873 US6056968A (en) 1997-03-11 1998-03-11 Pharmaceutical drug dosage forms providing different release rates

Publications (2)

Publication Number Publication Date
IL131713A0 IL131713A0 (en) 2001-03-19
IL131713A true IL131713A (en) 2004-08-31

Family

ID=27268767

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13171398A IL131713A (en) 1997-03-11 1998-03-11 Dosage forms comprising separate portions of r- and s-enantiomers

Country Status (15)

Country Link
US (2) US6056968A (es)
EP (1) EP0969818B1 (es)
JP (1) JP2001514651A (es)
CN (1) CN1251987A (es)
AT (1) ATE275394T1 (es)
AU (1) AU741821B2 (es)
BR (1) BR9808325A (es)
CA (1) CA2285407C (es)
DE (1) DE69826113T2 (es)
ES (1) ES2227814T3 (es)
HU (1) HUP0000759A3 (es)
IL (1) IL131713A (es)
NO (1) NO994412L (es)
PL (1) PL335619A1 (es)
WO (1) WO1998040053A1 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
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US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
JP2002531431A (ja) * 1998-12-02 2002-09-24 ダーウィン・ディスカバリー・リミテッド 治療用製品およびその使用
WO2000043003A1 (en) * 1999-01-21 2000-07-27 Darwin Discovery Limited The therapeutic use of r-warfarin as anticoagulant
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
PE20010623A1 (es) * 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
EP1313460A2 (en) * 1999-11-09 2003-05-28 Darwin Discovery Limited Therapeutic use and formulation of (-)-tramadol
DE10004926A1 (de) 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
DE60107393T2 (de) 2000-03-01 2005-12-01 Euro-Celtique S.A. Verwendung von tramadol zur herstellung eines arzneimittels zur behandlung von funktionelle gastrointestinale krankenheiten
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
JP2004513091A (ja) * 2000-10-03 2004-04-30 ペンウェスト ファーマシューティカルズ カンパニー 異なる速度の複数の医薬活性成分の送達系
CA2426811A1 (en) * 2000-10-24 2002-08-29 Smithkline Beecham Corporation Novel formulations of carvedilol
US6562871B1 (en) * 2000-11-06 2003-05-13 Boehringer Ingelheim Pharmaceuticals, Inc. Dry granulation of pharmaceutical formulation comprising mexiletine
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
IN191028B (es) * 2001-05-17 2003-09-13 Sun Pharmaceutical Ind Ltd
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
AU2002364517A1 (en) 2001-11-30 2003-06-17 Sepracor Inc. Tramadol analogs and uses thereof
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
WO2004041252A1 (en) * 2002-11-08 2004-05-21 Egalet A/S Controlled release carvedilol compositions
AU2003288608A1 (en) * 2002-12-20 2004-07-14 Ranbaxy Laboratories Limited Controlled release, multiple unit drug delivery systems
ES2293223T3 (es) * 2003-02-10 2008-03-16 Shire Canada Inc. Composiciones enantiomericas de anfetamina para el tratamiento de adhd.
WO2004103361A2 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited A pharmaceutical dosage form of citalopram
CA2528249C (fr) * 2003-06-06 2013-03-05 Ethypharm Comprime orodispersible multicouche
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
JP2007512350A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール組成物の治療および送達方法
US20050175695A1 (en) * 2003-11-25 2005-08-11 Catherine Castan Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
JP5254616B2 (ja) 2004-09-13 2013-08-07 クロノ セラピューティクス、インコーポレイテッド 生物学的同調性(biosynchronous)経皮的薬物送達
US20080038344A1 (en) * 2004-10-01 2008-02-14 Nippon Zoki Pharmaceutical Co., Ltd. Solid Pharmaceutical Preparation
CA2616204C (en) 2005-09-09 2015-12-01 Labopharm Inc. Sustained drug release composition
EP1976488A4 (en) * 2006-01-12 2010-02-10 Wockhardt Ltd ALFUZOSIN PROLONGED RELEASE PREPARATIONS
WO2007114376A1 (ja) * 2006-03-30 2007-10-11 Nippon Zoki Pharmaceutical Co., Ltd. 固形医薬製剤
CA2677691C (en) 2007-02-12 2012-07-31 David Bar-Or Reducing side effects of tramadol
KR20140054312A (ko) * 2007-02-12 2014-05-08 디엠아이 바이오사이언시스 인코포레이티드 조루 및 발기부전을 동시에 치료하는 방법
WO2008122049A2 (en) 2007-04-02 2008-10-09 Parkinson's Institute Methods and compositions for reduction of side effects of therapeutic treatments
EP3250258A4 (en) 2015-01-28 2018-09-05 Chrono Therapeutics, Inc. Drug delivery methods and systems
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 経皮薬剤送達の装置及び方法
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818541A (en) * 1987-08-19 1989-04-04 Schering Corporation Transdermal delivery of enantiomers of phenylpropanolamine
US5145866A (en) * 1991-04-22 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated Method of treating anxiety with the aid of r(+)-3-amino-1-hydroxy-pyrrolidin-2-one
US5204116A (en) * 1991-05-01 1993-04-20 Alza Corporation Dosage form providing immediate therapy followed by prolonged therapy
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
GB9412689D0 (en) * 1994-06-23 1994-08-10 Chiroscience Ltd Cytotoxic agent and its use

Also Published As

Publication number Publication date
HUP0000759A3 (en) 2000-11-28
CN1251987A (zh) 2000-05-03
AU741821B2 (en) 2001-12-13
NO994412D0 (no) 1999-09-10
ATE275394T1 (de) 2004-09-15
WO1998040053A1 (en) 1998-09-17
US6056968A (en) 2000-05-02
DE69826113D1 (de) 2004-10-14
JP2001514651A (ja) 2001-09-11
IL131713A0 (en) 2001-03-19
ES2227814T3 (es) 2005-04-01
US6221394B1 (en) 2001-04-24
AU6508998A (en) 1998-09-29
PL335619A1 (en) 2000-05-08
BR9808325A (pt) 2000-05-16
NO994412L (no) 1999-10-20
HUP0000759A2 (hu) 2000-10-28
EP0969818A1 (en) 2000-01-12
CA2285407A1 (en) 1998-09-17
CA2285407C (en) 2006-08-01
DE69826113T2 (de) 2005-01-20
EP0969818B1 (en) 2004-09-08

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees