IL129358A0 - Novel heterocyclically substituted benzamides and their use in fighting diseases - Google Patents

Novel heterocyclically substituted benzamides and their use in fighting diseases

Info

Publication number
IL129358A0
IL129358A0 IL12935897A IL12935897A IL129358A0 IL 129358 A0 IL129358 A0 IL 129358A0 IL 12935897 A IL12935897 A IL 12935897A IL 12935897 A IL12935897 A IL 12935897A IL 129358 A0 IL129358 A0 IL 129358A0
Authority
IL
Israel
Prior art keywords
substituted benzamides
heterocyclically substituted
fighting diseases
novel
novel heterocyclically
Prior art date
Application number
IL12935897A
Other languages
English (en)
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of IL129358A0 publication Critical patent/IL129358A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
IL12935897A 1996-12-09 1997-11-28 Novel heterocyclically substituted benzamides and their use in fighting diseases IL129358A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19650975A DE19650975A1 (de) 1996-12-09 1996-12-09 Neue heterocyclisch substituierte Benzamide und deren Anwendung
PCT/EP1997/006653 WO1998025899A1 (de) 1996-12-09 1997-11-28 Neue heterocyclisch substituierte benzamide und deren anwendung bei der bekämpfung von krankheiten

Publications (1)

Publication Number Publication Date
IL129358A0 true IL129358A0 (en) 2000-02-17

Family

ID=7814035

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12935897A IL129358A0 (en) 1996-12-09 1997-11-28 Novel heterocyclically substituted benzamides and their use in fighting diseases

Country Status (24)

Country Link
US (2) US6172072B1 (de)
EP (1) EP0946509A1 (de)
JP (1) JP2001505889A (de)
KR (1) KR20000057445A (de)
CN (1) CN1239949A (de)
AR (1) AR010339A1 (de)
AU (1) AU742732B2 (de)
BG (1) BG63388B1 (de)
BR (1) BR9713884A (de)
CA (1) CA2273988A1 (de)
CO (1) CO4910161A1 (de)
CZ (1) CZ292391B6 (de)
DE (1) DE19650975A1 (de)
HR (1) HRP970671A2 (de)
HU (1) HUP0000496A3 (de)
ID (1) ID22490A (de)
IL (1) IL129358A0 (de)
NO (1) NO992770L (de)
NZ (1) NZ335066A (de)
SK (1) SK56699A3 (de)
TR (1) TR199901282T2 (de)
TW (1) TW420666B (de)
WO (1) WO1998025899A1 (de)
ZA (1) ZA9710979B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010042839A (ko) * 1998-04-20 2001-05-25 스타르크, 카르크 시스테인 프로테아제를 억제하는 효과를 나타내고헤테로시클릭 치환체가 있는 신규 아미드
RU2260009C2 (ru) * 1999-11-05 2005-09-10 Сосьете Де Консей Де Решерш Э Д'Аппликасьон Сьентифик (С.К.Р.А.С.) Новые гетероциклические соединения и их применение в качестве лекарственных средств
FR2800737B1 (fr) * 1999-11-05 2006-06-30 Sod Conseils Rech Applic Nouveaux composes heterocycliques et leur application a titre de medicaments
GB0031302D0 (en) * 2000-12-21 2001-01-31 Glaxo Group Ltd Napthalene derivatives
KR100962972B1 (ko) 2002-07-26 2010-06-09 주식회사유한양행 1-페닐피페리딘-3-온 유도체 및 그의 제조방법
EP1562897B1 (de) 2002-11-12 2009-09-16 Merck & Co., Inc. Phenylcarboxamide als beta-sekretase-hemmer zur behandlung von alzheimer
WO2005019188A1 (ja) * 2003-08-22 2005-03-03 Takeda Pharmaceutical Company Limited 縮合ピリミジン誘導体およびその用途
US7320992B2 (en) * 2003-08-25 2008-01-22 Amgen Inc. Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use
FR2863268B1 (fr) * 2003-12-09 2006-02-24 Sod Conseils Rech Applic Nouveaux derives du 2-hydroxytetrahydrofuranne et leur application a titre de medicaments
EP1700850B1 (de) * 2003-12-22 2015-07-15 Ajinomoto Co., Inc. Phenylalaninderivat
GB0416730D0 (en) 2004-07-27 2004-09-01 Novartis Ag Organic compounds
US20070010537A1 (en) * 2004-08-20 2007-01-11 Kazumasa Hamamura Fused pyramidine derivative and use thereof
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
US7834023B2 (en) * 2006-09-20 2010-11-16 Portola Pharmaceuticals, Inc. Substituted dihydroquinazolines as platelet ADP receptor inhibitors
PT2439205E (pt) 2006-12-29 2015-07-16 Abbvie Deutschland Compostos de carboxamida e seus usos como inibidores de calpaína
CN101686680B (zh) 2007-03-09 2015-12-09 伊沃泰克美国股份有限公司 作为p2x7调节剂的双环杂芳基化合物及其用途
TWI453019B (zh) 2007-12-28 2014-09-21 Abbvie Deutschland 甲醯胺化合物
TWI519530B (zh) 2009-02-20 2016-02-01 艾伯維德國有限及兩合公司 羰醯胺化合物及其作為鈣蛋白酶（ｃａｌｐａｉｎ）抑制劑之用途
US8236798B2 (en) 2009-05-07 2012-08-07 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors
US9051304B2 (en) 2009-12-22 2015-06-09 AbbVie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors V
US8598211B2 (en) 2009-12-22 2013-12-03 Abbvie Inc. Carboxamide compounds and their use as calpain inhibitors IV
CN102939126B (zh) 2010-04-30 2015-09-16 雅培心脏血管系统股份有限公司 呈现迅速膨胀和收缩的改进型球囊导管
US9062027B2 (en) 2010-12-09 2015-06-23 AbbVie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors V
SG11201406345XA (en) 2012-04-03 2014-11-27 Abbvie Deutschland Carboxamide compounds and their use as calpain inhibitors v
EP3426674A4 (de) 2016-03-09 2019-08-14 Blade Therapeutics, Inc. Cyclische keto-amid-verbindungen als calpain-modulatoren sowie verfahren zur herstellung und verwendung davon
EP3481835A4 (de) 2016-07-05 2020-02-26 Blade Therapeutics, Inc. Calpain-modulatoren und therapeutische verwendungen davon
SG10201912574WA (en) 2016-09-28 2020-02-27 Blade Therapeutics Inc Calpain modulators and therapeutic uses thereof
EP3886854A4 (de) 2018-11-30 2022-07-06 Nuvation Bio Inc. Pyrrol- und pyrazolverbindungen und verfahren zu deren verwendung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524663D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinazoline derivatives
DE3717828A1 (de) * 1987-05-27 1988-12-15 Hoechst Ag Siliziumhaltige benzoesaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz
DE4000204A1 (de) 1990-01-05 1991-07-11 Steag Ag Vorrichtung zum dosierten austragen von schuettfaehigem feststoff
EP0473551A1 (de) * 1990-08-31 1992-03-04 Ciba-Geigy Ag 3-Aryluracil-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Unkrautbekämpfungsmittel
EP0564650B1 (de) 1990-12-28 1995-09-20 Kyowa Hakko Kogyo Co., Ltd. Chinolinderivat
WO1992011850A2 (en) 1990-12-28 1992-07-23 Cortex Pharmaceuticals, Inc. Use of calpain inhibitors in the inhibition and treatment of neurodegeneration
CA2071621C (en) * 1991-06-19 1996-08-06 Ahihiko Hosoda Aldehyde derivatives
EP0650368A1 (de) 1992-06-24 1995-05-03 Cortex Pharmaceuticals, Inc. Verwendung von calpain inhibitoren in der inhibition und behandlung von medizinischen zuständen die mit einer erhöhten calpainaktivität assoziiert sind
US5541290A (en) 1993-06-24 1996-07-30 Harbeson; Scott L. Optically pure calpain inhibitor compounds

Also Published As

Publication number Publication date
SK56699A3 (en) 1999-10-08
BG63388B1 (bg) 2001-12-29
TR199901282T2 (xx) 1999-10-21
CA2273988A1 (en) 1998-06-18
CN1239949A (zh) 1999-12-29
ZA9710979B (en) 1999-06-18
NO992770D0 (no) 1999-06-08
CZ174399A3 (cs) 1999-08-11
HRP970671A2 (en) 1998-10-31
AU742732B2 (en) 2002-01-10
CO4910161A1 (es) 2000-04-24
EP0946509A1 (de) 1999-10-06
KR20000057445A (ko) 2000-09-15
TW420666B (en) 2001-02-01
AR010339A1 (es) 2000-06-07
NZ335066A (en) 2000-03-27
AU5558098A (en) 1998-07-03
DE19650975A1 (de) 1998-06-10
US6172072B1 (en) 2001-01-09
BR9713884A (pt) 2000-02-29
WO1998025899A1 (de) 1998-06-18
CZ292391B6 (cs) 2003-09-17
NO992770L (no) 1999-06-08
HUP0000496A3 (en) 2002-11-28
HUP0000496A2 (hu) 2000-09-28
JP2001505889A (ja) 2001-05-08
BG103399A (en) 2000-01-31
ID22490A (id) 1999-10-21
US6436949B1 (en) 2002-08-20

Similar Documents

Publication Publication Date Title
HUP0000496A3 (en) Heterocyclically substituted benzamides and their use in fighting diseases
IL116325A0 (en) Substituted 1h-imidazoles their preparation and use
IL126900A0 (en) Spiro-piperidine derivatives and their use as therapeutic agents
GB9518115D0 (en) Triazole derivatives and their use as therapeutic agents
GB9515775D0 (en) Piperidine derivatives and their use as therapeutic agents
IL120124A0 (en) Heteroaryl-oxazolidinones their preparation and use
CY2508B1 (en) Benzopyrans and their use as therapeutic agents
GB9712761D0 (en) Quinolines and their therapeutic use
IL116014A0 (en) Iminooxymethyleneanilides their preparation and their use
IL120970A0 (en) N-acetonylbenzamides their preparation and their use as fungicides
HU9603575D0 (en) Amino-acid-derivatives and their use as pesticide
IL116134A0 (en) Iminooxybenzylcrotonate esters their preparation and their use
ZA976547B (en) Lipid-binding proteins and their therapeutic and diagnostic use
AU1801297A (en) Spiro-ketal derivatives and their use as therapeutic agents
ZA954732B (en) Benzopyrans and their use as therapeutic agents
GB9616504D0 (en) Therapeutic product and its use
HU9602567D0 (en) N-aryl and n-alkylsulphonylaminals as pesticides
ZA9710000B (en) Quinolines and their therapeutic use
GB9416404D0 (en) New use and formulations
GB9406858D0 (en) New use and formulations
ZA958760B (en) Tropane-derivatives their preparation and use
ZA951726B (en) Carbamoylcarboxamides their preparation and their use
GB9616505D0 (en) Therapeutic product and its use
GB9616506D0 (en) Therapeutic product and its use
GB9616823D0 (en) Therapeutic product and its use