FR2800737B1 - Nouveaux composes heterocycliques et leur application a titre de medicaments - Google Patents

Nouveaux composes heterocycliques et leur application a titre de medicaments

Info

Publication number
FR2800737B1
FR2800737B1 FR9913858A FR9913858A FR2800737B1 FR 2800737 B1 FR2800737 B1 FR 2800737B1 FR 9913858 A FR9913858 A FR 9913858A FR 9913858 A FR9913858 A FR 9913858A FR 2800737 B1 FR2800737 B1 FR 2800737B1
Authority
FR
France
Prior art keywords
medicaments
heterocyclic compounds
novel heterocyclic
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9913858A
Other languages
English (en)
Other versions
FR2800737A1 (fr
Inventor
Serge Auvin
De Lassauniere Pierre Chabrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9913858A priority Critical patent/FR2800737B1/fr
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority to PCT/FR2000/003067 priority patent/WO2001032654A2/fr
Priority to PT00974646T priority patent/PT1233962E/pt
Priority to KR1020027005798A priority patent/KR100725198B1/ko
Priority to EP05077194A priority patent/EP1661564A1/fr
Priority to HU0203183A priority patent/HUP0203183A3/hu
Priority to MXPA02004442A priority patent/MXPA02004442A/es
Priority to CZ20021548A priority patent/CZ20021548A3/cs
Priority to IL14917700A priority patent/IL149177A0/xx
Priority to CNB008159262A priority patent/CN1317278C/zh
Priority to EP00974646A priority patent/EP1233962B1/fr
Priority to BR0015315-0A priority patent/BR0015315A/pt
Priority to DE60026348T priority patent/DE60026348T2/de
Priority to NZ518420A priority patent/NZ518420A/en
Priority to US10/111,994 priority patent/US6747024B1/en
Priority to PL355286A priority patent/PL200167B1/pl
Priority to JP2001534805A priority patent/JP2003513092A/ja
Priority to CA2389685A priority patent/CA2389685C/fr
Priority to AU12871/01A priority patent/AU781551B2/en
Priority to ES00974646T priority patent/ES2259617T3/es
Priority to RU2002114696/04A priority patent/RU2260009C2/ru
Priority to AT00974646T priority patent/ATE318809T1/de
Publication of FR2800737A1 publication Critical patent/FR2800737A1/fr
Priority to IL149177A priority patent/IL149177A/en
Priority to NO20022088A priority patent/NO20022088L/no
Priority to IS6371A priority patent/IS2297B/is
Priority to HK03105058.5A priority patent/HK1052706B/zh
Priority to US10/803,387 priority patent/US20040180936A1/en
Priority to AU2005203713A priority patent/AU2005203713A1/en
Publication of FR2800737B1 publication Critical patent/FR2800737B1/fr
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9913858A 1999-11-05 1999-11-05 Nouveaux composes heterocycliques et leur application a titre de medicaments Expired - Fee Related FR2800737B1 (fr)

Priority Applications (28)

Application Number Priority Date Filing Date Title
FR9913858A FR2800737B1 (fr) 1999-11-05 1999-11-05 Nouveaux composes heterocycliques et leur application a titre de medicaments
DE60026348T DE60026348T2 (de) 1999-11-05 2000-11-03 Heterocyclische verbindungen und ihre verwendung als medikamente
KR1020027005798A KR100725198B1 (ko) 1999-11-05 2000-11-03 신규 헤테로시클릭 화합물 및 의약으로서의 용도
EP05077194A EP1661564A1 (fr) 1999-11-05 2000-11-03 Nouveaux composés hétérocycliques et leur application à titre de médicaments
HU0203183A HUP0203183A3 (en) 1999-11-05 2000-11-03 Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use
MXPA02004442A MXPA02004442A (es) 1999-11-05 2000-11-03 Nuevos compuestos heterociclicos y su uso como medicamentos.
CA2389685A CA2389685C (fr) 1999-11-05 2000-11-03 Nouveaux composes heterocycliques et leur application a titre de medicaments
IL14917700A IL149177A0 (en) 1999-11-05 2000-11-03 Novel heterocyclic compounds and their use as medicines
CNB008159262A CN1317278C (zh) 1999-11-05 2000-11-03 新杂环化合物及它们作为药物的用途
EP00974646A EP1233962B1 (fr) 1999-11-05 2000-11-03 Composes heterocycliques et leur application a titre de medicaments
BR0015315-0A BR0015315A (pt) 1999-11-05 2000-11-03 Compostos, medicamentos, composições farmacêuticas, utilização de compostos e produtos industriais
PT00974646T PT1233962E (pt) 1999-11-05 2000-11-03 Compostos heterociclicos e a sua utilizacao como medicamentos
NZ518420A NZ518420A (en) 1999-11-05 2000-11-03 Heterocyclic compounds having an inhibitory activity on calpains or a trapping activity on reactive oxygen species (ROS's) and their use as medicines
US10/111,994 US6747024B1 (en) 1999-11-05 2000-11-03 Heterocyclic compounds and their use as medicines
PCT/FR2000/003067 WO2001032654A2 (fr) 1999-11-05 2000-11-03 Nouveaux composes heterocycliques et leur application a titre de medicaments
PL355286A PL200167B1 (pl) 1999-11-05 2000-11-03 Związki heterocykliczne o aktywności hamowania kalpain i/lub pułapkowania ROS, ich zastosowanie i kompozycje farmaceutyczne je zawierające oraz związki pośrednie
CZ20021548A CZ20021548A3 (cs) 1999-11-05 2000-11-03 Nové heterocyklické sloučeniny a jejich pouľití jako léků
AU12871/01A AU781551B2 (en) 1999-11-05 2000-11-03 Novel heterocyclic compounds and their use as medicines
ES00974646T ES2259617T3 (es) 1999-11-05 2000-11-03 Compuestos heterociclicos y su aplicacion como medicamentos.
RU2002114696/04A RU2260009C2 (ru) 1999-11-05 2000-11-03 Новые гетероциклические соединения и их применение в качестве лекарственных средств
AT00974646T ATE318809T1 (de) 1999-11-05 2000-11-03 Heterocyclische verbindungen und ihre verwendung als medikamente
JP2001534805A JP2003513092A (ja) 1999-11-05 2000-11-03 新規複素環化合物及びその医薬としての使用
IL149177A IL149177A (en) 1999-11-05 2002-04-16 Heterocyclic compounds and their use as drugs
NO20022088A NO20022088L (no) 1999-11-05 2002-05-02 Nye heterocykliske forbindelser og deres anvendelse som medisiner
IS6371A IS2297B (is) 1999-11-05 2002-05-03 Nýjar fenóþíasínafleiður og notkun þeirra sem lyfja
HK03105058.5A HK1052706B (zh) 1999-11-05 2003-07-14 新雜環化合物及它們作為藥物的用途
US10/803,387 US20040180936A1 (en) 1999-11-05 2004-03-16 Heterocyclic compounds and their use as medicaments
AU2005203713A AU2005203713A1 (en) 1999-11-05 2005-08-18 New heterocyclic compounds and their use as medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9913858A FR2800737B1 (fr) 1999-11-05 1999-11-05 Nouveaux composes heterocycliques et leur application a titre de medicaments

Publications (2)

Publication Number Publication Date
FR2800737A1 FR2800737A1 (fr) 2001-05-11
FR2800737B1 true FR2800737B1 (fr) 2006-06-30

Family

ID=9551743

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9913858A Expired - Fee Related FR2800737B1 (fr) 1999-11-05 1999-11-05 Nouveaux composes heterocycliques et leur application a titre de medicaments

Country Status (1)

Country Link
FR (1) FR2800737B1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2111930A1 (fr) * 1992-12-25 1994-06-26 Ryoichi Ando Derives d'aminocetones
NO943210L (no) * 1993-09-03 1995-03-06 Takeda Chemical Industries Ltd Laktolderivater, deres fremstilling og anvendelse
US5691368A (en) * 1995-01-11 1997-11-25 Hoechst Marion Roussel, Inc. Substituted oxazolidine calpain and/or cathepsin B inhibitors
EP0925786A4 (fr) * 1996-07-10 2000-08-16 Mitsubishi Chem Corp Agents de traitement des maladies ischemiques
DE19650975A1 (de) * 1996-12-09 1998-06-10 Basf Ag Neue heterocyclisch substituierte Benzamide und deren Anwendung

Also Published As

Publication number Publication date
FR2800737A1 (fr) 2001-05-11

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Legal Events

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ST Notification of lapse

Effective date: 20140731