IL127365A0 - Insulin preparations containing carbohydrates - Google Patents

Insulin preparations containing carbohydrates

Info

Publication number
IL127365A0
IL127365A0 IL12736597A IL12736597A IL127365A0 IL 127365 A0 IL127365 A0 IL 127365A0 IL 12736597 A IL12736597 A IL 12736597A IL 12736597 A IL12736597 A IL 12736597A IL 127365 A0 IL127365 A0 IL 127365A0
Authority
IL
Israel
Prior art keywords
carbohydrate
insulin preparations
preparations containing
containing carbohydrates
carbon atoms
Prior art date
Application number
IL12736597A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL127365A0 publication Critical patent/IL127365A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
IL12736597A 1996-06-20 1997-06-19 Insulin preparations containing carbohydrates IL127365A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK68496 1996-06-20
DK89996 1996-08-27
PCT/DK1997/000267 WO1997048413A1 (en) 1996-06-20 1997-06-19 Insulin preparations containing carbohydrates

Publications (1)

Publication Number Publication Date
IL127365A0 true IL127365A0 (en) 1999-10-28

Family

ID=26064448

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12736597A IL127365A0 (en) 1996-06-20 1997-06-19 Insulin preparations containing carbohydrates

Country Status (16)

Country Link
EP (1) EP0910402B1 (zh)
JP (2) JP4472027B2 (zh)
KR (1) KR20000022030A (zh)
CN (1) CN1198643C (zh)
AT (1) ATE369146T1 (zh)
AU (1) AU719361B2 (zh)
BR (1) BR9709844A (zh)
CA (1) CA2258099A1 (zh)
CZ (1) CZ297682B6 (zh)
DE (1) DE69737995T2 (zh)
ES (1) ES2292189T3 (zh)
HU (1) HUP9904156A3 (zh)
IL (1) IL127365A0 (zh)
NO (1) NO324276B1 (zh)
PL (1) PL188736B1 (zh)
WO (1) WO1997048413A1 (zh)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1276731A (zh) 1997-10-24 2000-12-13 伊莱利利公司 不溶性胰岛素组合物
ZA989644B (en) * 1997-10-24 2000-04-25 Lilly Co Eli Insoluble insulen compositions.
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
EP1396272A1 (en) * 1997-12-23 2004-03-10 Eli Lilly & Company Insoluble Insulin Compositions for Controlling Blood Glucose
WO1999048520A1 (en) * 1998-03-24 1999-09-30 Joergensen Klavs Holger Novel preparation of protracted acting human insulin
GB9806462D0 (en) * 1998-03-26 1998-05-27 Glaxo Group Ltd Improved compositions for inhalation
US6211144B1 (en) 1998-10-16 2001-04-03 Novo Nordisk A/S Stable concentrated insulin preparations for pulmonary delivery
CN1210058C (zh) * 1998-10-16 2005-07-13 诺沃挪第克公司 用于肺送递的稳定的浓缩胰岛素制剂
US6635617B1 (en) 1998-10-16 2003-10-21 Novo Nordisk A/S Insulin preparations for pulmonary delivery containing menthol
EP1121145B1 (en) * 1998-10-16 2002-04-17 Novo Nordisk A/S Insulin preparations for pulmonary delivery containing menthol
DE602004012731T2 (de) * 2003-05-01 2009-04-09 Ltt Bio-Pharma Co., Ltd. Zubereitungen mit verzögerter freigabe enthaltend zink, und herstellung derselben
PL2918286T3 (pl) * 2004-10-05 2020-06-29 Novo Nordisk A/S Preparat farmaceutyczny zawierający insulinę w postaci krystalicznej, jak również w formie rozpuszczonej
CN101060856B (zh) * 2004-11-22 2011-01-19 诺和诺德公司 可溶、稳定的含胰岛素制剂
CN1931360B (zh) * 2006-09-22 2013-02-13 江苏万邦生化医药股份有限公司 双时相精蛋白锌胰岛素注射液(30%)及其制备方法
CA2711749A1 (en) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
RS56632B1 (sr) 2008-10-17 2018-03-30 Sanofi Aventis Deutschland Kombinacija insulina i glp-1-agonista
CN102711804B (zh) 2009-11-13 2015-09-16 赛诺菲-安万特德国有限公司 包含glp-1激动剂和甲硫氨酸的药物组合物
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
JP6199186B2 (ja) 2010-08-30 2017-09-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 2型糖尿病の治療用の医薬の製造のためのave0010の使用
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
JP6367115B2 (ja) 2011-08-29 2018-08-01 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 2型糖尿病患者の血糖コントロールに使用する組合せ医薬
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TWI780236B (zh) 2013-02-04 2022-10-11 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
JP2020143105A (ja) * 2014-01-09 2020-09-10 サノフイSanofi インスリンアスパルトの安定化された医薬製剤
MX2016008978A (es) * 2014-01-09 2016-10-04 Sanofi Sa Formulaciones farmaceuticas de analogos de insulina y/o derivados de insulina estabilizadas y que estan libres de glicerol.
JP2020114861A (ja) * 2014-01-09 2020-07-30 サノフイSanofi インスリンアナログおよび/またはインスリン誘導体の、グリセリンを含まない安定化された医薬製剤
JP7173953B2 (ja) * 2014-01-09 2022-11-16 サノフイ インスリンアナログおよび/またはインスリン誘導体の安定化された医薬製剤
CN105899190B (zh) * 2014-01-09 2022-06-14 赛诺菲 门冬胰岛素的稳定化药物制剂
CN112957455A (zh) * 2014-01-09 2021-06-15 赛诺菲 胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂
MX2017007699A (es) 2014-12-12 2017-09-18 Sanofi Aventis Deutschland Formulacion de proporcion fija de insulina glargina/lixisenatida.
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
WO2017163159A1 (en) * 2016-03-21 2017-09-28 Wockhardt Limited Biphasic pharmaceutical composition of insulin human

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439181A (en) * 1981-01-26 1984-03-27 Regents Of The University Of Minnesota Polyol-hormone mixture for use in chronic parenteral hormone administration
US4839341A (en) * 1984-05-29 1989-06-13 Eli Lilly And Company Stabilized insulin formulations
US4876241A (en) * 1987-05-22 1989-10-24 Armour Pharmaceutical Company Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
DK0705275T3 (da) * 1993-06-21 1999-09-20 Novo Nordisk As AspB28-insulin-krystaller

Also Published As

Publication number Publication date
BR9709844A (pt) 1999-08-10
JP4472027B2 (ja) 2010-06-02
PL330828A1 (en) 1999-06-07
AU3166597A (en) 1998-01-07
DE69737995D1 (de) 2007-09-20
JP2000513343A (ja) 2000-10-10
CA2258099A1 (en) 1997-12-24
CZ395798A3 (cs) 1999-05-12
EP0910402A1 (en) 1999-04-28
CN1198643C (zh) 2005-04-27
ES2292189T3 (es) 2008-03-01
JP2009242400A (ja) 2009-10-22
NO985978D0 (no) 1998-12-18
HUP9904156A2 (hu) 2000-06-28
WO1997048413A1 (en) 1997-12-24
ATE369146T1 (de) 2007-08-15
PL188736B1 (pl) 2005-04-29
CN1222084A (zh) 1999-07-07
AU719361B2 (en) 2000-05-04
EP0910402B1 (en) 2007-08-08
HUP9904156A3 (en) 2000-07-28
KR20000022030A (ko) 2000-04-25
NO985978L (no) 1999-02-19
DE69737995T2 (de) 2008-04-24
CZ297682B6 (cs) 2007-03-07
NO324276B1 (no) 2007-09-17

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